Xiuqian Mu researches genes involved in retinal
development.
Over the past decade, UB’s stem cell research has brought
together investigators to explore and translate the promise of stem
cells into effective clinical therapies and treatments for diseases
from Parkinson’s to muscular dystrophy to diabetes.
Add glaucoma to the mix in the work of Xiuqian
Mu. The soft-spoken scientist worked on retinal development at
the M.D. Anderson Cancer Center in Houston before arriving at UB in
2008. Of the offers he fielded, the opening at UB proved the most
attractive. “I felt the environment was right for me: the
people, the facilities, this brand new center and the other
institutes around here,” he says.
A member of the Developmental Genomics Group at UB’s Center of Excellence in Bioinformatics and Life Sciences, Mu researches genes involved in the development of the retina and how they might repair retinal damage. “The hope is that if we understand how retinal ganglion cells are formed and maintained, we may be able to understand the causes of their deaths,” he says. “We eventually may be able to make these cells for therapeutic purposes.”
Mu’s research interest developed from his curiosity as a child growing up in a small village of Shandong province in eastern China. Fascinated by chemistry and how things react, he would take apart household gadgets to see what made them work. Despite their humble means, his parents encouraged him to study to become a doctor.
After graduating from medical school, Mu pursued a PhD in
molecular biology at Beijing’s prestigious Peking Union
Medical College. In the early 1990s he received a fellowship with
the National Institutes of Health.
Mu seems to have found a home at the Center of Excellence and
values its interdisciplinary mission. “My research involves a
lot of genomics as well as bioinformatics, and I need collaborators
in those fields. It’s very, very easy to collaborate with
people here and that’s a big advantage,” he says.
“I’ve also made friends with people from different
departments. The support of people here has been very
helpful.”
Mu is enthusiastic about the development of UB’s Downtown
Campus. He enjoys playing basketball on weekends with a group of
Chinese postdocs and students in UB’s Alumni Arena. And he
has developed an appreciation for the area.
“Buffalo has a great history and there is so much around,
particularly the architecture. People are very, very friendly. I
think with the environment and people, it’s all here for me
to do what I want to do.”