Karl O. A. Yu MD, PhD, FAAP

Karl O. Yu

Karl O. A. Yu
MD, PhD, FAAP

Clinical Assistant Professor

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Immunology; Infectious Disease; Pediatric Infectious Diseases; Pediatrics

Contact Information
UBMD Pediatrics
Division of Infectious Diseases
1001 Main Street
Buffalo, NY 14203
Phone: (716) 323-0150
Fax: (716) 323-0296
kyu10@buffalo.edu


Patient Care

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Education and Training:

  • Fellowship, Pediatric Infectious Diseases, University of Chicago Medical Center (2014)
  • Residency, Pediatrics, Cohen Children‘s Medical Center of New York, Hofstra/Northwell Health (formerly North Shore LIJ Health System) (2011)
  • Internship, Pediatrics, Cohen Children‘s Medical Center of New York, Hofstra/Northwell Health (formerly North Shore LIJ Health System) (2009)
  • MD, Medicine, Albert Einstein College of Medicine of Yeshiva University (2008)
  • PhD, Microbiology and Immunology, Albert Einstein College of Medicine of Yeshiva University (2008)
  • MS, Microbiology and Immunology, Albert Einstein College of Medicine of Yeshiva University (2002)
  • BA, Biochemistry, Hiram College, Summa Cum Laude (2000)

Employment:

  • Consultant, Pediatric Infectious Diseases, Sisters of Charity Hospital (2019-present)
  • Clinical Assistant Professor, Pediatrics, University at Buffalo (2018-present)
  • Infection Prevention Officer, Oishei Children‘s Hospital (2018-present)
  • Attending Physician, Infectious Diseases, UBMD Pediatrics, Oishei Children's Hospital (2018-present)
  • Assistant Director, Center for Infectious Diseases and Immunology, Rochester General Hospital, Rochester General Hospital Research Institute (2017–2018)
  • Clinical Associate, Pediatrics, University of Chicago, Pritzker School of Medicine (2017)
  • Instructor, Pediatrics, University of Chicago, Pritzker School of Medicine (2015–2017)
  • Inpatient Consultant, Edward Hospital (2015–2017)
  • Clinical Instructor, Pediatrics, University of Chicago, Pritzker School of Medicine (2014–2015)

Awards and Honors:

  • Castle Connolly Medical Ltd: America‘s Top Doctors (2020)
  • University of Chicago Pediatric Research Day: Research Poster Award for Junior Faculty (Translational Research) (2016)
  • Clinical Immunology Society Annual Meeting: Travel Grant (2015)
  • ID Week: Travel Grant (2014)
  • Pediatric Infectious Diseases Society: Pediatric Fellow Poster Award (2014)
  • St. Jude Children‘s Research Hospital/Pediatric Infectious Diseases Society Research Conference: Travel Grant (2014)
  • Clinical Immunology Society School of Primary Immunodeficiencies: Travel Grant (2013)
  • Midwest AIDS Training and Education Center: MATEC Clinical Scholar (2012-2013) (2012)
  • Hiram College Department of Biology: J.J. Turner Society Member (2000)
  • Hiram College Department of Mathematics: Kenneth M. Hiney Mathematics Award (2000)
  • Albert Einstein College of Medicine Summer Undergraduate Research Program: Stipend (1999)
  • Hampshire College: Visiting Jerome K. Lemelson Fellowship (1998)
  • Hiram College: Vencl-Carr Research Assistantship (1998)
  • Hiram College Department of Biology: Paul Smey Award (1998-2000) (1998)
  • Hiram College: Dean‘s List (1997-2000) (1997)
  • Hiram College: Alpha Society (1997-2000) (1997)
  • Consortium for Mathematics and Its Applications/Mathematical Association of America: Mathematical Competition on Modeling - Honorable Mention (1997, 2000) (1997)
  • Hiram College: Trustees Global Scholar (1996-2000) (1996)
  • 37th International Mathematical Olympiad: National Delegate (1996)
  • Philippine Mathematical Olympiad: First Place (1995)

Grants and Sponsored Research:

  • April 2020–March 2021
    Immunologic and clinical studies on perinatal hepatitis C viral infection
    Wildermuth Foundation
    Role: Principal Investigator
    $35,000
  • December 2017–December 2019
    Microbiome and Virome in Children
    Merck
    Role: Co-Principal Investigator

Journal Articles:

See all (12 more)

Books and Book Chapters:

  • Yu KO, Burns JL. "Fever, a rash, and a ... ‘bug bite‘?". The Infectious Disease Diagnosis: A Case Approach. 2018.

Abstracts:

  • Yu KO, Nash CB, Nassin ML, Carlos CA, Van Slambrouck CV, Cheng JX, McNeer J, Rosebush JC. Disseminated Histoplasmosis Presenting with a Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome Phenotype in a Child with Pre-B Cell Acute Lymphoblastic Leukemia. J Clin Immunol. 2016; 36(3).
  • Yu KO, Bartlett AH. Invasive Aspergillosis and Chronic Granulomatous Disease Presenting in Early Infancy. J Clin Immunol. 2015; 35(3).
  • Yu KO, Randolph A, Bubeck Wardenburg J. Evidence for Staphylococcus aureus α-toxin as a Dominant Antigen in Severe Pediatric Influenza-staphylococcal Co-infection — Implications for Therapy. Open Forum Infect Dis. 2014; 1(S1).
  • Meyer-Bahlburg A, Andrews SF, Yu KO, Porcelli S, Rawlings DJ. Evidence for B Cell Antigen Receptor (BCR)-Driven, BAFF-Facilitated Positive Selection within a Unique Population of Late Transitional B Cells. Eur J Ped. 2009; 168.
  • Meyer-Bahlburg A, Andrews SF, Yu KO, Porcelli S, Rawlings DJ. Evidence for B Cell Antigen Receptor (BCR)-Driven, BAFF-Facilitated Positive Selection within a Unique Population of Late Transitional B Cells. FASEB J. 2008; 22(S1).
  • Yu KO, Wang C, Diamond B. Lupus: 1) Estrogen‘s Role in Autoimmune Induction and 2) An in vitro Glomerular Binding Assay for Autoantibody Pathogenicity. Ohio J Sci. 2000; 100(1).

Professional Memberships:

  • American Society for Microbiology: Western New York Branch (2019–present)
  • Clinical Immunology Society (2013–present)
  • Pediatric Infectious Diseases Society (2012–present)
  • American Academy of Pediatrics: Fellow (FAAP) (2011–present)
  • American Academy of Pediatrics (2008–present)
  • American Association of Immunologists (2007–2015)
  • American Association for the Advancement of Science (2007)
  • Ohio Academy of Science (2000)

Presentations:

  • "Lyme Disease vs. Lime Disease: A Rash Review" Education Day, WellNow Urgent Care (2020)
  • "Multiple Opportunistic Infections in a Hematopoietic Cell Transplant Patient Immunosuppressed with JAK and Complement Inhibitors" Annual Meeting, Clinical Immunology Society (2020)
  • "Lytic Bacteriophage Against an Emergent Biofilm-Forming Enteroinvasive Escherichia coli" Pediatric Infectious Diseases Research Conference, St. Jude Children‘s Research Hospital/Pediatric Infectious Diseases Society (2020)
  • "Antibiotics Boot Camp" Pediatrics Teaching Conference, University at Buffalo (2019)
  • "Not MRSA...Not MSSA...but Somewhere in Between" Fall Symposium, Western New York American Society for Microbiology (2019)
  • "Fifty Shades of M.R.S.A." Pediatric Infectious Diseases Clinical Conference, University at Buffalo (2019)
  • "Brincidofovir (CMX001) in dsDNA Viral Infections" Pediatric Hematology/Oncology Clinical Conference, University at Buffalo (2019)
  • "A Green Strep in the NICU" Pediatric Infectious Diseases Clinical Conference, University at Buffalo (2019)
  • "Hedging on Handling Hepatitis C" Pediatric Infectious Diseases Clinical Conference, University at Buffalo (2019)
  • "Evaluation for Primary Immunodeficiencies: A Peds ID Perspective" Pediatric Grand Rounds, St. Barnabas Medical Center (2019)
  • "Evaluation for Primary Immunodeficiencies: A Peds ID Perspective" Pediatric Grand Rounds, Children‘s Hospital of New Jersey (2019)
  • "A Series of Salmonella Syndromes" Pediatric Infectious Diseases Clinical Conference, University at Buffalo (2019)
  • "Epidemiology of Respiratory Infections" MPH Program, Daemen College (2019)
  • "Viruses and Antiviral Therapy" Pediatric Hematology/Oncology Clinical Conference, University at Buffalo (2019)
  • "A Peds ID View on Primary Immunodeficiencies" Pediatrics Teaching Conference, University at Buffalo (2018)
  • "Pneumovirus and Metapneumovirus" Pediatrics Teaching Conference, University at Buffalo (2018)
  • "When the M.R.S.A. Won‘t Go Away" Pediatric Infectious Diseases Clinical Conference, University at Buffalo (2018)
  • "Antibiotics Review" Pediatrics Teaching Conference, University at Buffalo (2018)
  • "A Translational View of Staphylococcus aureus α-toxin in Influenza-MRSA Co-Infection" Pediatric Infectious Diseases Seminar, University of Rochester Medical Center (2018)
  • "Kikuchi-Fujimoto Disease: An Important Diagnostic Consideration for Cervical Lymphadenitis in the Pediatric Population" Pediatric Infectious Diseases Research Conference, St. Jude Children‘s Research Hospital/Pediatric Infectious Diseases Society (2018)
  • "Case Series: Potential Infectious Etiologies for Kikuchi Fujimoto Disease in Children" Pediatric Research Day, University of Chicago (2017)
  • "Evaluation of Primary Immunodeficiencies (AKA...What I Learned in the Clinical Immunology Society's Summer School)" Pediatric Infectious Diseases Teaching Conference, University of Chicago (2017)
  • "Diagnosis and Treatment of Disseminated Toxoplasmosis Following Stem Cell Transplantation" Pediatric Infectious Diseases Research Conference, St. Jude Children's Research Hospital/Pediatric Infectious Diseases Society (2017)
  • "Translational Approaches in the Study of the Role of S. aureus α-toxin in Pediatric Influenza-Staphylococcal Co-Infection" Pediatric Grand Rounds, University at Buffalo (2017)
  • "Viruses and Antiviral Therapy" Pediatric Hematology/Oncology Teaching Conference, University of Chicago (2016)
  • "Translational Approaches in the Study of the Role of S. aureus α-toxin in Pediatric Influenza-Staphylococcal Co-Infection" Pediatric Grand Rounds, Comer Children‘s Hospital (2016)
  • "Translational Approaches in the Study of the Role of S. aureus α-toxin in Pediatric Influenza-Staphylococcal Co-Infection" Pediatric Research Day, University of Chicago (2016)
  • "Disseminated Histoplasmosis Presenting with a Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome Phenotype in a Child with Pre-B Cell Acute Lymphoblastic Leukemia" Annual Meeting, Clinical Immunology Society (2016)
  • "A Pediatric Infectious Disease/Primary Immunodeficiency Case" Pediatric Grand Rounds, Edward Hospital (2016)
  • "Peas in a Pod? Pneumovirus (RSV) and Human Metapneumovirus" Pediatric Grand Rounds, Community Hospital (2016)
  • "Influenza: Challenges and Updates" Pediatric Grand Rounds, Community Hospital (2015)
  • "Invasive Aspergillosis and Chronic Granulomatous Disease Presenting in Early Infancy" Annual Meeting, Clinical Immunology Society (2015)
  • "Evidence for Staphylococcus aureus α-toxin as a Dominant Antigen in Severe Pediatric Influenza-staphylococcal Co-Infection — Implications for Therapy" Annual Meeting, Pediatric Infectious Diseases Society (2014)
  • "Evidence for Staphylococcus aureus α-toxin as a Dominant Antigen in Severe Pediatric Influenza-staphylococcal Co-infection — Implications for Therapy" ID Week, Infectious Diseases Society of America (2014)
  • "A Translational Approach to the Investigation of Influenza-Staphylococcus aureus Co-Infection" Pediatric Infectious Diseases Research Conference, St. Jude Children's Research Hospital/Pediatric Infectious Diseases Society (2014)
  • "A Translational Approach to the Investigation of Influenza-Staphylococcus aureus Co-Infection" Pediatric Fellows Research Symposium, Comer Children's Hospital (2013)
  • "An Interesting Case of Pneumonia" School on Primary Immunodeficiencies, Clinical Immunology Society (2013)
  • "Pediatric Pneumonia" Pediatric Teaching Conference, Comer Children‘s Hospital (2013)
  • "Antibiotic Restriction - The Experience from a Medium-Sized Pediatric Tertiary Care Center" Pediatric Research Day, University of Chicago (2013)
  • "What is the Best Treatment for Complicated Pneumonias?" Pediatric Evidence-Based Learning Conference, North Shore-Long Island Jewish Medical Center (2011)
  • "Pediatric Pneumonia" Pediatric Teaching Conference, South Nassau Communities Hospital (2011)
  • "Monoclonal Antibodies Against Complexes of the NKT Cell Ligand α-galactosylceramide and Mouse CD1d" Frontiers in Basic Immunology Conference, National Cancer Institute (2009)
  • "Modulation of CD1d-Restricted NKT Cell Responses by Using N-acyl Variants of α-galactosylceramides" Summer Research Conference: Lymphocytes and the Immune System - Molecular, Cellular and Integrative Mechanisms, Federation of American Societies for Experimental Biology (2005)
  • "Structural Analogues of α-galactosylceramide as Novel Immunotherapeutic Agents" NIH Lupus Grant Site Visit, Albert Einstein College of Medicine (2003)
  • "Regulation of Marginal Zone B Cell Antibody Production by CD1d-Restricted T Cells" 2nd International Workshop on CD1 Antigen Presentation and NKT Cells (2002)
  • "Lupus: 1) Estrogen‘s Role in Autoimmune Induction and 2) An in vitro Glomerular Binding Assay for Autoantibody Pathogenicity" 109th Annual Meeting, Ohio Academy of Science (2000)
  • "Interactions Between Tannic Acid and Raphanus raphanistrum Root Acid Phosphatase" 43rd Annual May Conference, Society for Applied Spectroscopy (1999)
  • "A Study of the Price-Butler Method of Analyzing Tannin Content" Honors Convocation, Hiram College (1998)
  • "A Study of the Price-Butler Method of Analyzing Tannin Content" 2nd Annual Poster Session on Capitol Hill, Council for Undergraduate Research (1998)
See all (39 more)

Service Activities:

  • F1000Research; Ad Hoc Reviewer (2019)
  • Pediatric Infectious Diseases Society; Grant Reviewer (2018–present)
  • Pediatric Infectious Diseases Society: Research Affairs Committee; Committee Member (2018–present)
  • Journal of Infection; Ad Hoc Reviewer (2017)
  • Edward Hospital: Pediatric Infectious Diseases Inpatient Service; Consultant (2015–2017)
  • University of Chicago: Health4Chicago (Pediatric Infectious Diseases); Volunteer (2015–2016)
  • Antibodies; Ad Hoc Reviewer (2014)
  • University of Chicago Pritzker School of Medicine: Microbiology - Medical Biology (MICR 35900); Teacher (2013–2016)
  • University of Chicago Medical Center: Pediatric Infectious Diseases Section Conference; Coordinator (2012–2013)
  • Einstein Journal of Biology and Medicine; Editorial Board Member (2000–2006)
  • Frontiers in Immunology (2017, 2019); Ad Hoc Reviewer

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Contact Information

UBMD Pediatrics
Division of Infectious Diseases
1001 Main Street
Buffalo, NY 14203
Phone: (716) 323-0150
Fax: (716) 323-0296
kyu10@buffalo.edu

Looking for a doctor? This faculty member is affiliated with UBMD, the group comprised of practicing physicians who are also professors in the UB Jacobs School of Medicine and Biomedical Sciences.

View this faculty on UBMD