Provides transgenic approaches for the systematic dissection of the genetic, molecular, cellular and physiological mechanisms underlying complex biological processes.

Hosts analytical fluorescence-activated flow cytometers/cell sorters (FACS) and a state-of-the art high-speed cell sorter.

Identifies proteins in cell or tissue extracts using several different liquid chromotography/mass spectrometry based approaches.

Supplies the school and affiliated research programs with biochemical reagents.

Offers high-throughput, next-generation sequencing and gene-expression analysis services, including 3’-expression, miRNA, exon and gene arrays.

Houses a transmission electron microscope as well as light microscopes; consults with investigators and assists with equipment operation.

Carries out Sanger sequencing on a fee-for-service basis on instrumentation that typically provides reads of >600bp.

Allows investigators to analyze the kinetics of protein-protein and protein-ligand interactions.

Fabricates custom equipment and repairs and modifies instruments to researchers’ needs.

Characterizes and identifies epigenetic and transcription signatures of stem cells and their derived progeny using Next-Gen sequencing.

Analyzes xenobiotics and other metabolites, and supports OSHA-sponsored educational activities.

Engrafts stem cells into mice and other model systems; quantifies cell engraftment, migration and differentiation, and analyzes the behavior consequences of neural engraftment.

Helps investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors.

Contains a Zeiss LSM-510 Meta NLO laser scanning confocal microscope attached to a Zeiss-inverted microscope upgraded to multiphoton capability.

Provides multiparameter flow cytometry services for clinical diagnosis and follow-up, and to basic and clinical researchers.

Utilizes advanced PET radiopharmaceuticals/tracers and the latest PET/CT imaging technology to explore a wide variety of clinical and research questions.

Supports automated crystallization trials in a 1,536-well format, providing a key step in determining atomic scale molecular structures.

Provides facilities and technical assistance for processing and analyzing samples using electron microscopy.

Performs all procedures related to tissue preservation and histological analysis, including training on cryostat use and other protocols.

Maintains and banks stem cells, and provides stem cells and training to interested researchers.

Allows identification of differentially expressed proteins via peptide mass fingerprinting.