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Core Facilities

Maldi-Tof apparatus.

Proteomics/Maldi-Tof

We provide access to mass spectrometric fingerprinting of unknown proteins.

Maldi-Tof (Matrix-assisted, Laser-Desorption-Ionization/Time of flight) mass spectrometry is the method of choice to identify unknown proteins via mass analysis of proteolytic peptides and for characterization of post-translational modifications.

This technique is rapid, highly sensitive and applicable to a wide variety of research problems, including:

  • characterization of mutated proteins
  • estimating the extent of protein derivatization (e.g., biotinylation)
  • identification of unknown proteins isolated from polyacrylamide gels

Depending on the specific application and complexity of the system, you can obtain reliable data in the fmol-pmol range.

Location

118 Farber Hall

Reservations

Contact Information

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Kenneth Blumenthal

Director

Maldi-Tof Proteomics Facility

140 Farber Hall, University at Buffalo, Buffalo, NY 14214

Phone: (716) 829-2727; Fax: (716) 829-2725

Email: kblumen@buffalo.edu