Addictions; Internal Medicine
I work full- time in Addiction Medicine. My patient clientele are those with Addiction related issues (Alcohol, opiates, benzodiazepines, etc) that need Medically Assisted Treatment. I am a Buprenorphine prescriber, and I also work at a Methadone clinic. For patients requesting help, please call the 716 – 247 -5281 number.
Internal Medicine; Infectious Disease
I am an attending physician on the Infectious Diseases service at Roswell Park Cancer Institute (RPCI). My clinical duties include inpatient and outpatient consultations at RPCI and on-call duties at Buffalo General Medical Center. In addition to providing clinical care, I teach medical students, residents and fellows in daily rounds and through formal didactic lectures. My primary research interest focuses on the epidemiology, pathogenesis, prevention and treatment of opportunistic infections in patients with hematologic malignancies and recipients of hematopoietic stem cell transplantation. In addition, I study the epidemiology, pathogenesis and transmission of colonization and infection by vancomycin resistant Enterococcus in patients with hematologic malignancies. My long-term goal is to define strategies to prevent transmission, determine virulence and decrease the mortality associated with these infections. Finally, I participate as a site principal investigator in several multicenter clinical trials.
Internal Medicine; Nephrology
I am the acting chief of nephrology services at the Buffalo VA Medical Center (VAMC). My clinical work includes caring for both inpatients and outpatients diagnosed with a variety of kidney diseases. I have expertise in caring for patients with chronic kidney disease (CKD) and acute kidney injury. I also direct dialysis services at the VAMC. In this role, I care for dialysis patients and oversee quality improvement activities to ensure the best possible care for our VAMC dialysis patients. I have a broad background in nephrology and specific training and expertise in key research areas such as CKD and acute kidney injury. My main research interest is to determine reversible factors to prevent acute kidney injury. I am also studying preventable causes of CKD and have expanded my research to include the care of elderly patients who have been diagnosed with CKD. I am committed to education, and I teach medical students, residents and fellows, primarily at the VAMC. I am one of the key faculty in the “renal module” for first-year medical students: I give four lectures and participate in six small-group sessions each year. During my inpatient consult service, I teach residents and fellows.
Internal Medicine; Pediatrics; Internal Medicine - General; Internal Medicine - Pediatrics
Francis W Peabody said: “… the secret of the care of the patient is in caring for the patient” I am a primary care physician to adults and children, forging long-term relationships with my patients and their families, as their doctor from birth to death. I am board-certified in internal medicine and pediatrics. My mission in medicine is four-fold: to provide empathetic and expert patient care, to teach and train the next generation of physicians, research and global health. I practice in UBMD’s Division of Internal Medicine at Conventus-- part of the Buffalo Niagara medical campus. I therefore offer easy access primary care to all staff and students in the medical campus, and their families. I have a Ph.D. in biochemistry and worked for a decade as a scientist and professor. I therefore have an interest in genetic and metabolic disorders. I led adult cystic fibrosis care for five years at the Marshfield Clinic in Wisconsin. I continue to provide care to patients with these congenital diseases. I have a decade of experience in training different learners in the outpatient setting, on international medical mission trips and in the hospital. My research is on bacteriophages -- their role in the microbiome of the respiratory tract and in genomic predictors of pathogenicity in bacteria. I also do research on problems I have seen in my patient population – suicidal ideation and risk in high school students and obesity in children. I believe a good history and physical exam can reduce needless testing in the search for a diagnosis. My skills have been honed by practice in Africa and Latin America. I was a short-term Ebola Clinician in Sierra Leone during the 2014-2015 outbreak and remain committed to delivering healthcare internationally. I offer primary care support to specialty services and welcome learners and collaborators in our mission to provide excellent healthcare to populations locally and globally.
Internal Medicine; Internal Medicine - General
I provide outpatient primary care service at Erie County Medical Center. I treat patients with multiple chronic medical problems such as diabetes, hypertension, obesity and high cholesterol, providing proactive, preventative and compassionate care for these complex cases. My practice emphasizes coordinating care across interdisciplinary teams and helping patients make therapeutic lifestyle changes through diet, exercise and weight loss. I take great pleasure in working with diverse, underserved patients, including patients with mental illnesses, helping them understand their disease, overcome barriers to treatment and address the causes of noncompliance. As a medical director of the Internal Medicine Clinic, I am actively engaged in several ongoing quality improvement projects to improve patient safety and the quality of care we provide. I have led initiatives to design and optimize clinical workflows and to implement Allscript Enterprise Electronic Health Records (EHR) in all outpatient clinics at ECMC, building a framework to provide consistent care throughout our health care system. Through benchmarking evidence-based national quality standards and providing physician leadership in using EHR and Patient-Centered Medical Home (PCMH) programs, I hope to lay the groundwork for a twenty-first century health care system. I am passionate about teaching and education. I provide mentoring, teaching and supervision for medical students and the 33 residents at our clinic. Our quality improvements projects have been presented at various national annual conferences, including American College Of Physicians( ACP) and Society of General Internal Medicine. We have published QI projects in BMJ open quality journal. My goal is to create great leaders and excellent physicians for the future.
Cardiology; Cardiovascular Disease; Internal Medicine
As director of the Division of Cardiology at the Buffalo VA Medical Center (Buffalo VAMC), I oversee cardiac care, education and research. My division is one of the most efficient across similar VA facilities: it provides the full spectrum of cardiovascular diagnostic and therapeutic services while maintaining outcomes that meet or exceed all nationally mandated standards. I see outpatients in my own clinic, and I see inpatients as well, including those admitted to the Intensive Care Unit (ICU). My practice focuses on coronary artery disease (CAD), congestive heart failure, atrial fibrillation and valvular abnormalities. I approach my patients by practicing both the art and science of medicine and spend ample time getting to know my patients and the social structures that surround them. I believe that the care of a patient is much more effective when the patient is treated as a person rather than a diagnosis. I truly enjoy my clinical sessions at the Buffalo VAMC where I meet new and returning veterans who share their stories with me. It is a privilege to care for each of these amazing individuals. The abundance of complex cases at the Buffalo VAMC, along with extensive longitudinal electronic health data, allows us to conduct clinical research to improve patient care. We physician-scientists at the Buffalo VAMC are increasing our focus on clinical research to complement the bench research performed at UB. My current research is studying the role of post-traumatic stress disorder (PTSD) in heart disease. While longitudinal studies indicate a role of PTSD on CAD prevalence and outcomes, its causative mechanism has been debated. My colleagues and I are looking at mental stress-induced myocardial ischemia (MSIMI) and how this differs in patients with PTSD. I am passionate about teaching and feel a strong responsibility to mentor the next generation of physicians. I trained as a Royal College of Physicians educator in order to become a better medical educator. To me, mentorship involves more than just teaching the facts of medicine. I emphasize interpersonal and communication skills with the fellows I train, in addition to traditional bedside teaching, because these patient-centered abilities are essential to being a good physician. I also help trainees navigate increasingly complex hospital and health care environments. The knowledge I share with them about the systems that are part of modern health care is also key to providing the best care to patients.
Cardiology; Cardiovascular Disease; Clinical Cardiac Electrophysiology; Internal Medicine
An internationally recognized cardiovascular physician-scientist, Dr. Cain is a specialist in abnormal heart rhythms. He is board-certified in internal medicine, cardiovascular diseases and clinical cardiac electrophysiology and pacing. He is a fellow of the American College of Cardiology, the American Heart Association and the Heart Rhythm Society. A former associate editor of Circulation, Cain is a member of the editorial boards of the American Journal of Cardiology, the Journal of Cardiovascular Electrophysiology, Nature Clinical Practice Cardiovascular Medicine and Heart Rhythm. His NIH-supported research has focused on determining the mechanisms of life-threatening heart rhythm abnormalities that occur in heart attacks and other conditions that damage heart muscle cells. This information is being used to better characterize and more accurately localize the abnormal heart tissue responsible for these abnormal heart rhythms and to improve the identification of patients at increased risk for sudden cardiac death.
Internal Medicine; Nephrology
I am trained as a general nephrologist and as an epidemiologist. I have interest in kidney stones prevention and in dialysis in general. I did extra training in hemodialysis prior to working as a community nephrologist for 14 years. I have significant experience in caring for dialysis patients including in acute and chronic renal failure and in various settings comprising intensive care unit, emergency department, chronic outpatient and home dialysis (this includes both hemodialysis and peritoneal dialysis). I care for patients in my general nephrology clinics twice a week. In that clinic I see patients with acute kidney injury, chronic kidney disease (hereditary or acquired), complications of chronic kidney disease, hypertension, electrolytes anomalies, glomerulonephritis or kidney stones. I am an attending for the nephrology service provided at Erie County Medical Center and at Roswell Park Comprehensive Cancer Center. I oversee care for chronic outpatient hemodialysis individuals. I also provide care for patients on home hemodialysis and peritoneal dialysis both at Erie County Medical Center and Clevehill Dialysis Unit (DaVita). I am currently the medical director for the home dialysis program at Erie County Medical Center. My research interests are with infection prevention in dialysis patients including vaccination, kidney stone prevention, interventions to delay end stage renal disease in chronic kidney disease population. I am involved with clinical teaching while on inpatients rotation. Teaching is provided to medical students, residents and fellows. I participate also in the renal fellows’ longitudinal clinic.
Internal Medicine; Nephrology; Bioinformatics; Molecular Basis of Disease; Cardiac pharmacology
I have a passion for challenge and an allergy to routine. This has driven my interest for research and clinical medicine, mainly internal medicine. I am currently a nephrologist at UBMD and a Faculty at the University at Buffalo Jacobs School of Medicine and Biomedical Sciences. In my clinical practice, I manage all aspects of kidney disease, renal replacement therapies including dialytic therapies and kidney transplant, hypertension, as well as disorders of fluid and electrolytes. With my group, I also provide nephrology consultations at the Roswell Park Cancer Institute. I particularly favor this part of my clinical activity, considering the very specific and challenging nephrological problems arising in cancer patients. I have a passion for education and never say no for opportunities to teach or learn. At the expense of longer days, I always take opportunities to teach fellows, residents and students. I strongly believe in problem-based learning, in the sense that what is learned is best remembered as a solution to a problem. So far, my research has focused on cardiovascular disease, mainly cardiac and vascular mechanics. In this phase of my career in nephrology, I am moving towards issues interfacing the cardiovascular system and the kidneys.
Internal Medicine; Public Health and General Preventive Medicine
I am a primary care physician specialized in both internal medicine and preventive medicine. As a member of the UBMD Internal Medicine primary care team, I see patients at the Hertel-Elmwood Internal Medicine Center. My clinical work focuses on providing high value care for patients with acute and complex chronic conditions, including diabetes, heart failure, asthma, chronic obstructive pulmonary disease (COPD) and hypertension. I have worked as a physician in both Peru and the United States, and my ability to speak English and Spanish fluently—in addition to my multicultural background--allows me to relate to, and care effectively for a broad patient population. My ability to reach across cultural divides helps build trust in my patients, an essential component in rendering individualized, compassionate care. I have a special interest in translating evidence-based innovations, using quality improvement tools, to enhance the care of patients with multiple chronic diseases. I am interested in research that strives to understand the social determinants of health, i.e., how socioeconomic circumstances, neighborhood environments and psychosocial factors affect the prevention and treatment of chronic conditions. I am specifically interested in how social determinants affect the treatment of patients with Type 2 diabetes. My goal in this research is to understand the multiple factors affecting health and wellness in order to help ameliorate the disparities found in the health care of vulnerable populations. I train medical students and residents as they rotate in the Hertel-Elmwood Internal Medicine Center. I emphasize to trainees that building a healing longitudinal relationship with patients is as important as mastering the science of medicine in delivering effective and compassionate patient care. Furthermore, I encourage trainees to look not only “downstream” for the causes of diseases but “upstream” as well in order to offer holistic approaches for the prevention and treatment of diseases that affect our Buffalo and Western New York community.
Internal Medicine; Nephrology
My breadth of clinical practice is broad; I care for patients with a wide range of both acute and chronic renal diseases. This includes patients with electrolyte abnormalities, autoimmune and/or secondary glomerulonephritides and polycystic kidney disease as well as those who have undergone kidney transplantation. My training at the Weill Cornell Hypertension Center has provided me with focused training in the management of refractory, secondary and perinatal hypertension. Therefore, I also see patients with refractory or difficult-to-control hypertension even though they may not have kidney dysfunction. As medical director of the Erie County Medical Center (ECMC) Living Donor Kidney Transplant Program, I see many prospective living donor kidney candidates during their donor evaluation process, and I follow them in the post-operative period. I see patients in a variety of inpatient and outpatient settings. I serve as the nephrology attending physician on the inpatient Renal Medicine and Renal Consultation services at ECMC as well as the Renal Consult service at the Buffalo Niagara Medical Campus (BNMC). My outpatient clinics include my weekly general UBMD Nephrology and Transplant clinics at ECMC and my weekly general UBMD Nephrology clinic at the Niagara Falls Renal Office. I care for both in-center and home hemodialysis as well as peritoneal dialysis (PD) patients receiving services at numerous dialysis centers located throughout Erie and Niagara Counties. I work with national and global kidney care groups such as Fresenius and DaVita to provide care for my patients, and I serve as medical director for several of their Western New York dialysis centers. My clinical research interests are also wide-ranging. I have particular interests in medication, chemotherapy and toxin-induced kidney injury. I have worked on a project that investigated the long-term renal impacts of the chemotherapy agent ifosfamide in adult cancer patients. I also have a research interest in autosomal dominant adult polycystic kidney disease (AD-PKD). I am involved in a multicenter clinical trial to compare the efficacy and safety of the drug Tolvaptan to determine if it can help to slow, or even halt the progression of renal cysts and thereby delay or prevent progression of end-stage kidney disease in people with AD-PKD. I supervise and teach physicians at all stages of their training, including interns and residents from UB’s internal medicine residency program as well as fellows in UB’s nephrology training program. I supervise trainees on both the inpatient Renal Medicine and Renal Consult services and in the outpatient Renal and Hypertension Clinic and the outpatient Transplant Clinic. In addition to bedside teaching, I sometimes teach small group nephrology seminars for third-and fourth-year medical students rotating on their medicine clerkships. I also provide lectures for the internal medicine resident teaching program and for the nephrology fellowship teaching program.
Internal Medicine; Internal Medicine - General
I graduated from the University of Buffalo School of Medicine and completed a residency in Internal Medicine at UB as well. I was a Chief Resident in 1990 and subsequently joined the Department of Medicine as a faculty member in the Division of General Internal Medicine. I served as an Associate Program Director for the Internal Medicine resident training program until 2008. From 2002 until 2008 I became involved in hospital administration and served as the Chief Medical Officer for the Erie County Medical Center. From 2008 until 2011 I served as the Chief Medical Officer for the Seneca Nation Health Department. During that time I completed a Masters of Public Health at the Mailman School of Public Health at Columbia University. In 2011 I returned full time to the Department of Medicine as Division Chief of General Internal Medicine and to ECMCC as an Associate Medical Director. Throughout my career I have been very interested in medical education, quality improvement and patient safety. In my role at ECMC I have been charged with improving the patient experience and have focused on patient and physician communication. We are currently assessing barriers to effective communication and developing interventions to improve the quality of physician and patient interactions.
As the Clerkship Director for 3rd and 4th year required Medicine Clerkships, my main interest is student education. My goal is for every student, regardless of their future career goals, to acquire the knowledge, skills and attitudes to provide basic medical care to their patients. For the 3rd year students, I have developed a practical examination to assess interpretation of commonly encountered problems on chest radiographs, ECGs, hematologic smears, microbiologic samples and electrolyte disorders. The 4th year in-house exam requires students to manage 2 patients initial presentation to discharge in a step wise manner. As a management attending on the inpatient teaching service at Buffalo General Medical Center, my focus is to serve as a role model for providing effective and empathetic care to all patients.
Cardiovascular Disease; Internal Medicine; Nephrology; Pathophysiology; Vascular and Interventional Radiology; Cardiac pharmacology
(1) Role of the sympathoadrenal system in hypertension, postural adaptation, and long-term cardiovascular adaptation (2) Control of regional and systemic blood flow during acute stress responses (3) Mechanisms of stress responses and vasoreactivity, both in vivo and in vitro, including metabolic interactions (4) Cardiovascular drug effects (5) Outcomes of drug therapies
Addictions; Gastroenterology; Internal Medicine; Liver (Hepatology); Infectious Disease
I care for patients with liver disease and addiction disorders, including opiate dependency, viral hepatitis, alcoholic and fatty liver disease, in an outpatient setting at Erie County Medical Center where I am the medical director of hepatology. In collaboration with the division of infectious diseases, I also evaluate and treat patients with hepatitis C virus (HCV) and HIV co-infection. I also treat veterans with opiate dependency at the Buffalo VA Medical Center, in the addiction medicine unit. My patient-care efforts include digital outreach: I co-authored an article for the inaugural issue of the patient-oriented online magazine “HCV Next.” My research involves improving hepatitis C treatments in populations disproportionately affected by HCV but with limited access to health care (including many American veterans, ethnic minority groups, injection drug users, and patients with psychological disorders) as well as developing novel modalities to deliver care. The goal of my research is to expand HCV treatment services to a wide-ranging group of patients, especially those without immediate access to care, in an effort to reduce global disease burden. This may include training primary care or other providers to treat HCV and using telemedicine and co-localization as a way to increase treatment uptake in areas such as rural primary care clinics and methadone clinics. My team is also investigating barriers to hepatitis C screening and treatment. Using the data we collect (e.g., patients’ knowledge of the disease, their perceptions regarding treatment, their willingness to be treated), we can design initiatives to improve patient-based HCV education and work toward the goal of increasing treatment uptake. This component of my research also looks at the same issues on the provider side: provider HCV knowledge and screening, referral and treatment practices. These data will help us understand what the provider-level barriers are to disease control, and we can design provider-based HCV educational initiatives to improve screening and referral for care. I am also a co-investigator on numerous clinical trials related to new therapeutic agents for hepatitis C and fatty liver disease, including a study funded by the Centers for Disease Control and Prevention (CDC) to evaluate the use of telemedicine to treat HCV in methadone maintenance clinics. I present and lecture nationally about hepatitis C with an emphasis on opiate dependence and special populations. I am a member of the New York State Hepatitis C Demonstration Project expert panel. I teach medical students in small group settings in the area of gastroenterology and hepatology. I also precept internal medicine residents and gastroenterology fellows in the outpatient clinics.
I am a primary care physician, board-certified in internal medicine. I see patients at the UBMD Internal Medicine office on Youngs Road in Williamsville. I take a holistic approach to my patients and am part of a “medical home” model of patient care. This means I work as part of a team: I collaborate with other physicians and health care professionals to provide comprehensive and continuous medical care to my patients, with the goal of obtaining the best possible health outcomes. I focus, too, on preventive care and believe that it is important to help patients lead a lifestyle that will maximize their health. I also teach medical students. My goal is to teach students to become compassionate physicians who care for patients holistically and in the context of their families, their cultures and their communities. I have been recognized with numerous teaching awards throughout my career. I serve as well as the senior associate dean for student and academic affairs. As such, I am responsible for medical admissions, multicultural affairs, student services, registrar services, student disciplinary matters and the school’s Clinical Competency Center and simulation centers. I am also the program director for STEP (Science and Technology Entry Program) and director of the post-baccalaureate program. My overall goals are to support strong pipeline programs that help ensure a diverse student body, attract academically talented students who show the potential to become compassionate physicians, provide our students with a variety of hands-on opportunities in research, training and innovative learning experiences--and help our students succeed at every stage in their medical education. My office is structured to support our students throughout the four years of medical school, both with academic advising and personal counselling services.
Critical Care Medicine; Pulmonary & Critical Care Medicine; Internal Medicine; Pulmonary; Sleep Medicine
My clinical responsibilities include serving as an intensivist to patients requiring critical care and participating in the care of hospitalized patients with pulmonary problems at the Buffalo VA Medical Center (Buffalo VAMC). I also diagnose and manage outpatients with sleep problems at the Buffalo VAMC. My clinical research interests include asthma in the elderly and the impact of passive smoke on respiratory health. I also have been exploring novel appreciative assessment approaches to raise resilience and prevent burnout in faculty and medical trainees. In addition, I have a keen interest in working on strategies to enhance faculty mentoring skills. In addition to my clinical and research responsibility, I am passionate about educating future generations of health care professionals, and I help train and mentor medical students from the first to final year of medical school. I am one of the seminar leaders for the Clinical Practice of Medicine course. As such, I help train first-year students in clinical skills. I also play an active role in mentoring medical students, helping them to develop into compassionate and well-rounded physicians who have sound clinical skills as well as the humanistic qualities that are exhibited in the best medical care. As a member of the steering committee for the medical school’s Center for Medical Humanities, I am involved in designing a humanistic curriculum to prepare the next generation of physicians. I facilitate sessions with second- and third-year medical students, with the goal of supporting and fostering humanism. I teach students how to develop their ability to use self-awareness of knowledge, skill and emotional limitations in order to engage in appropriate help-seeking behaviors. As the associate clerkship director in internal medicine, I run “brain teasers” sessions to excite and activate my students as they embark on their clerkship journey into medicine. I conduct lectures and small group sessions in pulmonary and critical care medicine, on topics such as asthma, chest x-ray interpretation, pulmonary function testing and shock--and on topics diverse from my subspecialty such as rheumatology, infectious disease and hematology. In addition, I teach medicine residents and the pulmonary, critical care and sleep medicine fellowship trainees who rotate with me on the inpatient and outpatient services. As a preceptor and member of the Resident Clinical Competency Committee, I provide support and career advice to residents during their training. I believe the ability to think creatively is essential in the medical field, and I strive to help students and physicians-in-training overcome creative barriers. I develop methods to guide students to think “out of the box” and to be inquisitive, and I encourage them to apply these skills to help recognize problems, solve medical cases and design research and clinical treatment.
Adolescent Medicine; Children and Adults; Internal Medicine; Pediatrics
As a specialist in adult and pediatric care, I practice general primary care for both children and adults. I also provide specialized care for adolescents and young adults who have a wide range of health and psychosocial conditions and concerns, including eating disorders, gynecologic issues, sexual health concerns and complex chronic disease. My academic interests focus on adolescent resiliency, i.e., a teenager’s ability to overcome adversity. Those with more resiliency tend to cope better with chronic disease or negative experiences and are less likely to engage in risk-taking behaviors. I am particularly interested in the role resiliency plays in my patients’ quality of life in the face of their chronic health conditions. I am also interested in its role in preventing risk-taking behaviors—specifically, high-risk sexual behaviors that lead to teenage pregnancy. My resident research project focused on the relationship between resiliency and perceived quality of life in adolescent mothers, a research area that I continue to explore. My goal with these research foci is to develop ways to improve resiliency among adolescents in our community, through coursework in our high schools, perhaps, or through after-school programs. As a faculty member in internal medicine and pediatrics, I am involved in resident and medical student education. I teach evidence-based medicine and its clinical application, keeping current with journal articles and reviews, using data to modify my clinical practice, when indicated--and encouraging these practices in residents and medical students. I participate as well in introducing both first- and second-year medical students into the clinical setting via the Clinical Practice of Medicine (CPM) course they are required to take. Students come to my primary care office to shadow me and to practice their history-taking and physical-exam skills. I also lecture at the monthly medicine-pediatrics conferences; recent topics have included contraception and proteinuria in pediatric patients.
Internal Medicine; Pulmonary Disease; Infectious Disease
My area of expertise is in infectious diseases in adults and I evaluate and treat adults with all infections, without restriction to a special area, and see patients within the Veterans Affairs hospital system. I act as a consultant for other physicians treating patients who have, or are suspected to have, infectious diseases in hospital settings or outside the hospital. Prior to becoming an infectious disease specialist, I had training and work experience in surgery as well as internal medicine. This exposure has helped me in my current clinical practice since infections occur in patients after surgical procedures. Having a firsthand understanding of what surgeons do allows me to understand the patient’s overall situation better. I teach first- and second-year medical students, primarily in pulmonary, in small group sessions. My research is focused on bacterial infections in patients with chronic obstructive pulmonary disease (emphysema and chronic bronchitis, known also as COPD). I am especially interested in how the host (the human body) reacts to the pathogen (the bacteria), and how differences in the host determine the outcome of the encounter between host and pathogen. Recently, we found that airway epithelial cells from patients with COPD respond to pathogenic bacteria in a manner that is different from healthy, non-COPD people. My goal is to further characterize and understand the cellular mechanisms underlying this aberrant behavior in COPD. I expect this research to open new avenues of therapy specially tailored to intervene in the host-pathogen interaction. Students and fellows have the opportunity to conduct research with me. I collaborate with Sanjay Sethi, MD and Charles Berenson, MD from the department of medicine.
Cardiology; Cardiovascular Disease; Internal Medicine; Radiology; Cardiopulmonary physiology; Autoimmunity; Cardiac pharmacology; Gene Expression; Immunology; Stem Cells
I am a cardiologist with specialized training in advanced cardiac imaging. I see outpatients at the Heart and Lung Center of Buffalo General Medicine Center (BGMC), and I care for inpatients through the cardiology consult and inpatient services at BGMC. As an advanced imaging cardiologist, I am responsible for developing and advancing the cardiac computed tomography (CT) and magnetic resonance imaging (MRI) programs at the Gates Vascular Institute (GVI) and providing these services to patients. These advanced, noninvasive imaging techniques allow physicians to perform in-depth, 3-D evaluation of the coronary tree, myocardium, heart valves, pericardium and great vessels. These imaging tools allow for the best possible diagnoses and care of patients. My research spans basic science, translational and clinical fields and combines the cross-discipline expertise on magnetic resonance (MR) technology with molecular biology. My overall goal is to study the consequences of ischemia-induced myocardial injury, with a focus on their therapeutic reversal. My research laboratory at UB’s Clinical and Translational Research Center (CTRC) is devoted to the development of novel time-and-tissue-targeted MRI methods for integrative understanding of cardiovascular pathophysiology in preclinical models. We have several interesting research projects, e.g., we have recently discovered that the presence of high-risk plaques in the carotid arteries predict future incidence of myocardial infarction and stroke. The results emphasize that the nature of atherosclerosis and the use of comprehensive non-invasive computed tomography angiography (CTA) will help identify patients who are at higher risk of developing ischemic stroke. These research results will help physicians employ early therapeutic strategies for these high-risk patients. I mentor medical students, residents and fellows both in clinical and research settings, and I precept cardiology fellows at the Heart and Lung Center at BGMC. In addition, I am deeply engaged in furthering the research and clinical education of our house staff. Our trainees have published their research in highly esteemed peer-reviewed journals, and many have routinely presented their work at national and international scientific conferences. I am committed to facilitating the career goals of my mentees while I continue to advance my own career as a clinician, researcher and mentor.
I am a member of the Division of General Internal Medicine, which consists of a team of dedicated professionals providing exceptional preventive care, acute care, and chronic disease management for adults across the entire spectrum of health and disease. I work closely with and supervise University at Buffalo students and residents in their care of patients at the Internal Medicine Center at ECMC and in the care of hospitalized patients at ECMC. I am also engaged in research on alcoholism and alcohol-related disease, including the detection and treatment of these commonly encountered conditions in medical settings. Alcohol-related problems are often unrecognized due to a lack of specific diagnostic testing or simply not linking heavy drinking to problems that are not always or not usually alcohol-related (e.g., hypertension). If alcohol is recognized as a problem, tools to treat alcoholism have not typically been adapted for primary care nor have many physicians received specific training in managing alcoholism. With the support of the National Institutes of Health and other organizations, I conduct cutting-edge research on the assessment and treatment of patients with alcohol-related disease using brief counseling methods and medications that are appropriate for primary care practices. I am also heavily involved in studying the use of novel laboratory tests for detecting unhealthy drinking patterns and alcohol-related organ damage. My goal as a clinical researcher is to provide tools that enable physicians to provide care for alcohol-related disorders as they do for other chronic diseases such as diabetes and high cholesterol. This includes the use of laboratory tests to monitor control of the disease, guide the use of medications and brief counseling in busy medical settings, and determine the need for more intensive treatment or referral to addiction specialists.
I am Clinical Faculty in the Division of General Internal Medicine. I see patients and supervise residents in Internal Medicine and medical students at the Primary Medicine Center at Buffalo General Hospital. I am interested in scholarship relating to medical education, quality of care, and helping patients adopt healthy behaviors.
Internal Medicine; Nephrology; Renal Transplantation
My main goal is extending and improving native kidney and renal transplant function. Over the last 15 years, I have focused my efforts on transplant renal management and acute kidney injury. I completed my nephrology and transplant training at Harvard in Massachusetts, and have been part of a busy group at The Ohio State University Transplant Center for the last 13 years as an attending and clinical researcher. I recently assumed the Medical Director of Transplant and Renal Services as part of the Erie County Medical Center/University at Buffalo, NY. Hot areas of clinical research concentrate on antibody-mediated rejection, new immune suppression and recurrent diseases post kidney transplant, and prevention and management of acute kidney injury and delayed transplant renal function. Through studies of immune suppression effects and impact on renal function and disease recurrence, we are hoping to improve early graft function and prevent disease recurrence. I have also been participating in novel pharmaceutical studies for management of transplant related injury and infections as well as artificial organ devices for bridge therapies including stem cells and pre-determined precursor kidney cells. My original PhD studies were in Neuroscience, at the University of Maryland Medical System, where I worked on growth factors for central nervous system (brain and spine) regeneration. Unfortunately, CNS injury repair continues to be under developed. The immune system plays a crucial role in the normal competition between true tissue repair and scarring. This recognition and the large population with renal diseases and transplant led me to transition in to kidney diseases and injury repair and transplant. While treatment and recovery from stroke have languished, chronic kidney disease and dialysis therapy have blossomed during the last 50 years, and renal transplant has become the gold standard for renal replacement therapy and live kidney donation has the best results. My research experience and publications span the fields of renal disease, transplant, and recovery. I contribute to national and international transplant meetings and educational efforts in transplant and nephrology in the American Society for Transplantation and the American Society of Nephrology for the development of new therapies and policies for better renal outcomes. Promoting renal transplant through education, clinical research and outreach are prime targets for transplant success. As an educator, I support nephrology and immunology lectures and conferences in medical school, graduate students and specialty fellowship training; working to develop the leaders of tomorrow in this field. Volunteerism and philanthropy are also important, passionate causes in raising awareness and funding for clinical studies, patient support and organ donation.