Faculty Profiles

Daniel, Bednarek
Bednarek, Daniel, PhD, FAAPMProfessor: Radiology; Neurosurgery; Physiology & Biophysics
Email: bednarek@buffalo.edu
Phone: 716-898-4193

Specialty/Research Focus:
Radiological Physics

Research Summary:
A specialist in radiological imaging physics & radiation safety, Dr. Bednarek is board certified in Diagnostic, Therapeutic & Medical Nuclear Physics. He was a charter member of the AAPM Commission on Accreditation of Educational Programs for Medical Physicists and has served the ABR as oral examiner & as a member & chair of the diagnostic radiology physics written examination committee for over 17 years. He has served as Associate Editor & Reviewer for the Journal Medical Physics & is a member of the ACR Mammography Interpretive Skills Assessment Committee. He is a fellow of the AAPM & has received the Lifetime Service Award from the ABR. Dr. Bednarek is a research faculty member of the Toshiba Stroke and Vascular Research Center & Clinical Medical Physicist at the Erie County Medical Center. He has taught medical imaging physics & radiation safety for over 30 years to radiology residents, graduate students, medical students, and hospital staff. He has been engaged in research in region-of-interest imaging including development & evaluation of limited-field-of-view, high resolution real-time imaging detectors with specific application to neuroimaging. Recent work has focused on methods for determination of patient radiation dose and development of a real-time dose-tracking system for interventional fluoroscopic procedures.

Steven, de Boer
de Boer, Steven, MSSenior Medical Physicist, Research Assistant Professor
Email: sdeboer@buffalo.edu
Phone: (716) 845-8212

Specialty/Research Focus:
Radiological Physics

Research Summary:
Provides medical physicist services to Institute departments using radiation beams for therapy of disease; maintains quality assurance and calibration of radiotherapy equipment; provides consultation in radiation safety matters; participates in treatment design and delivery. Enhances professional growth and development by conducting and participating in educational programs, distributing and reading current literature, conducting and participating in in-service meetings and workshops.

Ciprian, Ionita
Ionita, Ciprian, PhDAssistant Professor
Email: cnionita@buffalo.edu
Phone: (716) 400-4283

Specialty/Research Focus:
Cardiovascular Disease; Diagnostic Radiology; Neuroradiology - Radiology; Radiological Physics; Vascular and Interventional Radiology; Vision science

Research Summary:
I am an Assistant Professor with a dual appointment in the Biomedical Engineering Department and Neurosurgery. I am the director of the Endovascular Devices and Imaging lab at Canon (former Toshiba) Stroke and Vascular Research Center. My research career focuses on improvement of endovascular image guided interventions and encompasses three major components: medical imaging, computer programming and endovascular device development. The greatest breakthrough of my team in the last three years is the development of complex 3D printed (3DP) vascular patient specific phantoms based on 3D imaging. Using my previous experience in developing CT reconstruction algorithms and 3D data analysis, this step came naturally. We are using these phantoms to test devices and validate software such as CT-FRR, parametric imaging and material decomposition using spectral CT. The 3DP phantoms we develop are probably some of the most complex reported in literature. We created new tools for 3D mesh manipulation and workflow to build complex vascular trees, which maintain vessel down to 400 microns diameter. My team collaborates directly with 3D printing industry and engineers in academy, to optimize the 3DP materials and match tissue mechanical properties. As center of excellence for 3D printing, we contribute to identification of new clinical applications for the 3DP technology, 3DP material development, and testing, and software development. One of the challenges my team is tackling, is the 3D printing material and 3D design optimization to build structures with controlled mechanical properties. In the last two years, my research focused on how to use the 3D printing technology to create digital structures which can simulate mechanical properties of vascular tissue, vascular networks and arterial disease. My effort is directed toward developing methods to warp 3D structures and embed them within the arterial wall. The embedded structures could be printed with different materials to different mechanical properties. This approach will allow optimization of phantom physical properties which match those of the arteries. Thus, by combining the 3D design with the new polymers used for the 3D printing while maintaining the patient specific geometry, I plan to develop a vascular model which will behave and react identical as a human vessel, both healthy and diseased. On a secondary effort on 3DP, my team is involved in developing implantable devices; we are collaborating with metal printing industries in testing methods to develop 3DP patient specific devices. We are able to reproduce coronary stents, which match the physical size/geometry of those used in current practice. However, mechanical and corrosion aspects need more investigations. In this context, I believe that additive manufacturing can be another path towards personalized medicine, by allowing manufacturing of patient specific devices rather than one size fits all kind of approach used by current device manufacturers. Concerning my involvement in the scientific community, in the last two years, I became deeply involved with the effort to implement the new advances of 3D printing into a clinical setting. I have given presentations and symposiums at conferences such as RSNA where I emphasized the new additive manufacturing advances and the close relation with the 3D medical imaging. The new digital material technologies, the improved resolution and fast building time make this technology practical for the high pace workflow in the hospitals. As of now I am involved with Special Interest Group from RSNA for standardization of 3DP printing operations in hospitals and development of a DICOM standard associated with the workflow and manufacturing of 3D printed medical objects.

Lalith, Kumaraswamy
Kumaraswamy, Lalith, PhDSenior Medical Physicist, Research Assistant Professor
Email: lk9@buffalo.edu
Phone: 716-845-1105

Specialty/Research Focus:
Radiological Physics

Research Summary:
Provides medical physicist services to Institute departments using radiation beams for therapy of disease; maintains quality assurance and calibration of radiotherapy equipment; provides consultation in radiation safety matters; participates in treatment design and delivery. Enhances professional growth and development by conducting and participating in educational programs, distributing and reading current literature, conducting and participating in in-service meetings and workshops.

Anh, Le
Le, Anh, PhDMedical Physicist, Research Assistant Professor
Email: ahle2@buffalo.edu
Phone: 716-845-1536

Specialty/Research Focus:
Radiological Physics

Research Summary:
Individual provides physics services to hospital departments using radiation beams for therapy of disease. These services include Quality Assurance and calibration of radiotherapy equipment, consultation in radiation safety matters and contribution to advances in treatment design and delivery.

Harish, Malhotra
Malhotra, Harish, PhD, DABRSenior Medical Physicist, Research Associate Professor
Email: hm22@buffalo.edu
Phone: (716) 845-1475

Specialty/Research Focus:
Radiological Physics

Daryl, Nazareth
Nazareth, Daryl, PhDSenior Medical Physicist, Research Assistant Professor
Email: dpn2@buffalo.edu
Phone: 716-845-4990

Specialty/Research Focus:
Radiological Physics

Research Summary:
Provides medical physicist services to Institute departments using radiation beams for therapy of disease; maintains quality assurance and calibration of radiotherapy equipment; provides consultation in radiation safety matters; participates in treatment design and delivery. Enhances professional growth and development by conducting and participating in educational programs, distributing and reading current literature, conducting and participating in in-service meetings and workshops.

Matthew, Podgorsak
Podgorsak, Matthew, PhD, FAAPM, DABMP, DABRChief Medical Physicist, Research Associate Professor
Email: podgorsa@buffalo.edu
Phone: 845-8054

Specialty/Research Focus:
Radiological Physics

Research Summary:
Research within the physics section of the department of Radiation Medicine at Roswell Park Cancer Institute deals with clinical applications of physics in the treatment of both malignant and benign disease. The Department of Radiation Medicine is undergoing expansion in both its Clinical programs and in its research activities. Currently, we have ongoing projects involving the most recently acquired piece of equipment, known as the gamma knife, used for the treatment of intracranial lesions. We are attempting to characterize the scatter radiation dose distribution within the environs of the gamma knife. Other projects include studies of the properties of electron beams used at extended treatment distances and evaluations of different types of in vivo dosimeters. Students who perform research under the auspices of the department of Radiation Medicine can expect to gain both theoretical knowledge of medical physics and the practical experience necessary to practice within the field.

Sanjay, Raina
Raina, Sanjay, PhDSenior Medical Physicist, Research Assistant Professor
Email: raina@buffalo.edu
Phone: 716-845-1562

Specialty/Research Focus:
Radiological Physics

Research Summary:
Provides medical physicist services to Institute departments using radiation beams for therapy of disease; maintains quality assurance and calibration of radiotherapy equipment; provides consultation in radiation safety matters; participates in treatment design and delivery.

Stephen, Rudin
Rudin, Stephen, PhD, FAAPM, DABR, CHPSUNY Distinguished Professor; Director, Division of Radiation Physics
Email: srudin@buffalo.edu
Phone: (716) 829-5408

Specialty/Research Focus:
Diagnostic Radiology; Neurological Surgery; Neuroradiology - Diagnostic Radiology; Neuroradiology - Radiology; Pediatric Radiology - Radiological Physics; Radiological Physics; Radiology; Vascular and Interventional Radiology

Research Summary:
A SUNY Distinguished Professor & member of the UB faculty for more than 30 years, Dr. Rudin is a world-renowned expert in the field of medical physics. The quintessential interdisciplinary research scientist, Dr. Rudin is an international force in the development of a host of cutting-edge technology & methodology in the area of medical diagnostic & interventional imaging. He has won multiple awards for scientific excellence as well as awards for excellence in design, and is particularly well-known for his work in developing a high resolution x-ray imaging detectors, dose reduction methods, and endovascular devices such as asymmetric stents, work with major theoretical and clinical implications for medical physics, biomedical engineering, and diagnostic radiology, as well as an immediate impact upon patient diagnosis and care, particularly in case of brain and heart treatment. The caliber, significance, and innovation of his research are demonstrated by the numerous grants he has received from the NIH.

Ferdinand, Schweser
Schweser, Ferdinand, PhDAssistant Professor of Neurology and Biomedical Engineering, Technical Director of MRI
Email: schweser@buffalo.edu
Phone: (716) 888-4718

Specialty/Research Focus:
Multiple Sclerosis; Neurodegenerative disorders; Neuroimaging; Neurology; Neuroradiology - Radiology; Parkinson's; Radiological Physics; Radiology; Bioinformatics

Research Summary:
Magnetic resonance imaging (MRI) is a unique technique for studying the human body since it is non-invasive, does not require ionizing radiation and offers a multiplicity of complementary tissue contrasts. My research seeks to explore the potential of MRI for clinical and pre-clinical imaging and to provide new and improved MRI technology. The goal of this endeavor is twofold: 1.) to contribute deeper insight into the etiology, pathogenesis and potential treatment of neurodegenerative diseases, and 2.) to give clinicians the ability to diagnose diseases earlier and monitor them more accurately. I am currently focusing on understanding MRI contrast mechanisms as well as on developing innovative imaging and reconstruction techniques that improve the sensitivity and specificity of MRI with respect to biophysical properties of brain tissue. Advancements in this field promise to have a substantial impact on our understanding of biophysical and morphological tissue alterations associated with neurological diseases and their treatment. We recently pioneered quantitative susceptibility mapping (QSM), a breakthrough in quantitative MRI. This technique allows for unique assessment of endogenous and exogenous magnetic particles in the human brain such as iron, calcium, myelin or contrast agents. The concept of QSM is fundamentally different from conventional MRI techniques as it involves solving for all imaging voxels simultaneously in large physically motivated equations, a so-called inverse problem. At the Buffalo Neuroimaging Analysis Center (BNAC), we use QSM to explore whether brain iron may serve as an early biomarker for diseases of the central nervous system such as multiple sclerosis and Parkinson’s disease. Other interesting applications of this technique we are investigating include differentiation between hemorrhages and calcifications, detection of demyelination and quantification of tissue oxygenation. I am fascinated by the synergies from combining physical expertise with high-level mathematical, numerical and engineering concepts to advance our understanding of the human brain. Consequently, my research activities are generally interdisciplinary and involve collaboration with clinicians, physicists, computer scientists, technicians and engineers. Student projects typically focus either on the application of techniques or on technical developments. Undergraduate, graduate and doctoral candidates from a variety of disciplines such as neuroscience, physics and mathematics work collaboratively in my lab.

Zhou (Iris), Wang
Wang, Zhou (Iris), PhDSenior Medical Physicist, Assistant Research Professor
Email: iwang@buffalo.edu
Phone: 716-845-3367

Specialty/Research Focus:
Radiological Physics

Research Summary:
Provides medical physicist services to Institute departments using radiation beams for therapy of disease; maintains quality assurance and calibration of radiotherapy equipment; provides consultation in radiation safety matters; participates in treatment design and delivery. Enhances professional growth and development by conducting and participating in educational programs, distributing and reading current literature, conducting and participating in in-service meetings and workshops.