Child Neurology; Epilepsy; Neuromuscular Disorders; Pediatrics
As a pediatric neurologist, my clinical practice focuses on the comprehensive neurologic care of infants, children and adolescents. Having completed fellowship training in clinical neurophysiology, my expertise focuses on the evaluation and management of epileptic and non-epileptic (stress-induced) seizures, as well as neuromuscular disorders, with particular skill in performing electroencephalography (EEG) and electromyography (EMG). I am one of the panel neurologists in the Epilepsy Monitoring Unit at the Women and Children’s Hospital of Buffalo (WCHOB). As a physician for the inpatient and outpatient neurology service, I attend to the needs of patients who present to WCHOB with a variety of neurologic symptoms. In addition to epilepsy and neuromuscular disorders, my clinical interest includes stroke in the young. I am fascinated by the various factors that may predispose infants and children to cerebrovascular ischemia. After an ischemic event, I work closely with the patients and their families to help coordinate long term care and rehabilitation in their road to recovery. I am actively involved in research mentorship and in the teaching of medical students, residents in adult neurology, pediatric neurology, pediatrics, psychiatry and fellows in clinical neurophysiology. I am further interested in autoimmune, demyelinating and infectious processes within the nervous system. After the 2009 influenza A - H1N1 pandemic, I extensively researched the neurologic complications of H1N1 in pediatric patients in Western New York. I compared our results to those of other groups in the global pediatric and neurologic communities. I presented my results at various international medical conferences. I feel fortunate to have participated in and conducted numerous clinical research projects. I have a track record of research, collaboration and publishing in the field of pediatric neurology. I intend to continue blending research with my clinical work, as I feel that both of these are essential for the art of practicing medicine.
General Neurology; Neurology; Neuromuscular Disorders
Edward J. Fine, MD is Associate Professor of Neurology at State University at Buffalo. He is Board-Certified in Neurology with Extra Qualifications in Clinical Neurophysiology. He specializes in the diagnosis and treatment of patients with neuromuscular disorders primarily and with epilepsy secondarily. Dr. Fine was born in Cincinnati, OH. He graduated cum laude from the Ohio University as a President’s Scholar. He was a Roessler Scholar and a graduate of The Ohio State University Medical School. His internship (PGY I training) was at Albert Einstein Medical School, Bronx, NY in Medicine. His PGY II was in neuropathology. He served Active Duty in the US Navy Medical Corps where he rose from Lt-jg to Commander. He served as Medical Officer to Destroyer Squadron 12 at sea and in the Naval Hospital at Newport, RI. He trained in Neurology at the Albany Medical Center in from 1970-2. He returned to Neuropathology as a Teaching Fellow at Brown University Medical School. Then he became Chief Resident in Neurology at the New Jersey University of Medicine and Dentistry in 1973. He joined and served on the faculty of the Rutgers Medical School (now Robert Wood Johnson, Jr., School of Medicine) in 1973-1978. At Brigham and Women’s Hospitals and Harvard Medical School, he mastered Clinical Neurophysiology from 1978-1979. Then he returned to Rutgers serving as Director of Neurological Services at the Robert Wood Johnson, Jr. Institute of Rehabilitation from 1980-1983. He joined the University at Buffalo in 1983. In 1993 and 1994 he received additional training in human physiology at the NIH-NINDS, Bethesda, MD. Dr. Fine has written 130 peer reviewed articles, book chapters and abstracts. He has published articles related to peripheral neuropathy, vitamin B12 deficiency and motor control. Dr Fine has an academic interest in the history of the neurosciences, serving as President of the International Society of the History of the Neurosciences in 2004 and on the editorial board of the Journal of the History of the Neurosciences from 2003 to present and Chair of Section of History of Neurology, American Academy of Neurology.
Multiple Sclerosis; Neuromuscular Disorders
I evaluate and care for patients who have neuroimmunological disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD) and other inflammatory- and autoimmune-mediated central and peripheral nervous system disorders. I completed a master‘s of science degree in clinical and translational investigation to better conduct translational research. My research interests focus on immune-mediated nervous system disorders--specifically, on predictive measures and outcomes research. In addition to participation in several clinical trials, I am actively investigating the prevalence and relationship between MS and neuropathy. I also have a particular interest in the pathophysiology of autonomic nervous system dysfunction in MS and the usefulness of autonomic measurements in developing treatment targets and predictive clinical measures in MS. The goal of my research is to better understand MS and to create better treatments that will positively impact patients‘ lives. I teach, train and mentor medical students and residents. I like to explore trainees‘ gaps of knowledge rather than tell them all the answers, a technique that I believe encourages physicians-in-training to think deeply and exhaustively about new areas of learning. I also teach trainees the art of physical exam techniques, which is a special area of interest to me. During medical school, I completed an enrichment program in social medicine and public health that gave me training and research in public health and health disparities. I use what I learned to sensitize medical students and residents to the myriad and complex issues related to the care of patients for whom medical care is often inaccessible.
Neurology; Neuromuscular Disorders
As a neurologist with advanced training in the field of neuromuscular disorders, I care for adults and children with disorders of nerves, muscle and the neuromuscular junction. I have specialized training in clinical neuromuscular medicine, and my expertise is not only in clinical care but also in performing electrodiagnostic studies (nerve conduction and electromyography). I am one of the few physicians in Western New York skilled at performing advanced electrophysiological techniques such as single fiber electromyography. I also perform skin biopsies and chemodenervation (botulinum toxin treatment) at our UBMD Neurology clinic on Main St. in Williamsville. As well, I evaluate and care for patients with general neurologic diseases such as headache and seizures. I see outpatients at Buffalo General Medical Center (BGMC), the UBMD Neurology Clinic and the Muscular Dystrophy Association clinic at BGMC, where I serve as co-director. I frequently attend on service at BGMC. I conduct both clinical research studies and basic science research in collaboration with physician-scientists from multiple disciplines, including neurology. My clinical research is focused on several studies that address illnesses such as Guillain-Barre syndrome, myasthenia gravis and polyneuropathy. These studies include both treatment trials--to find more effective treatments for these diseases--as well as research investigating the impact of the diseases on patients’ quality of life. In my basic science research, I collaborate with investigators at the Hunter James Kelly Research Institute to explore the pathophysiology of inherited neuropathies, which are known collectively as Charcot-Marie-Tooth (CMT) disease. My goal is to better understand the underlying cause or mechanisms of these diseases. My role in this research is performing electrophysiological studies on mice models. I welcome trainees to work with me on research; they should contact me directly to explore collaboration with me. In addition to my research and clinical care, I direct the adult neurology residency training program and train fellows in clinical neurophysiology. I am actively involved in teaching medical students in both the clinical and preclinical years, and I lecture extensively in the medical school and at national and international meetings on topics related to neuromuscular disorders. I serve on medical school committees that focus on improving medical and graduate medical education.
Neurology; Neuromuscular Disorders
I arrived in January 2012 to assume the role of Chair of the Department of Neurology at Univ. at Buffalo School of Medicine and Biomedical Sciences, the State University of New York. Prior to that time, I served as Professor of Neurology at University of Texas Southwestern Medical School in Dallas, Texas. In September 2004, I was named to the Dr. Bob and Jean Smith Foundation Distinguished Chair in Neuromuscular Disease Research. I also served as Co-Director of the Muscular Dystrophy Association Clinics and Director of the Myasthenia Gravis and Peripheral Neuropathy Clinics at UT Southwestern and was the Clinical Vice Chair for the department in Dallas. My interests in neuromuscular medicine are wide but have mainly focused on myasthenia gravis and other disorders of neuromuscular transmission, as well as peripheral neuropathies. I am board certified both in neurology and neuromuscular medicine. I am also board certified in neurophysiology, and I perform electromyography and nerve conduction studies and monitor intraoperative evoked potentials for spine surgeries and other operative cases. My main research interests include idiopathic and immune-mediated peripheral neuropathies and myasthenia gravis. My research has been sponsored by the National Institute of Health/NINDS, Muscular Dystrophy Association, Myasthenia Gravis Foundation of America, and Food and Drug Administration. I remain actively involved in the training of younger physicians, and have directed neuromuscular medicine and clinical neurophysiology fellowships and neurology residency training programs in the past.