Neonatal-Perinatal Medicine; Neonatology; Pediatrics
As chief of the Division of Neonatology in the Department of Pediatrics, I oversee and provide delivery of specialized, family-centered, advanced medical care to critically ill preterm and term newborn infants as well as support to their families. My practice is located in Western New York’s most advanced Neonatal Intensive Care Unit (NICU), at the Women and Children’s Hospital of Buffalo. I also practice at the Level II NICU at Millard Fillmore Suburban Hospital. As the director of the Center for Developmental Biology of the Lung, my research focuses on the pathophysiology of the cardiopulmonary transition – how fetal lungs change, at birth, to breathe air – and disorders of this transition, such as birth asphyxia, PPHN, retained lung liquid and respiratory distress syndrome. My laboratory’s translational research aims primarily at preventing and treating these disorders with optimal neonatal resuscitation techniques, steroids, nitric oxide, surfactant and judicious use of oxygen. I have an interest in managing newborn infants with hypoxic respiratory failure and persistent pulmonary hypertension of the newborn (PPHN) and have investigated the role oxygen-free radicals, nitric oxide and antioxidants play in the pathogenesis and management of PPHN. I currently focus on optimal strategies for neonatal resuscitation. My division is part of the Neonatal Research Network of the National Institute of Child Health and Human Development (NICHD), one of the National Institutes of Health (NIH) – a group of 15 academic neonatal centers conducting multicenter trials with the goal of improving outcomes in sick preterm and term neonates. Together, we work to transfer innovative discoveries from our laboratory to the bedside through clinical trials, improving outcomes for this vulnerable population. I am a committed professor and mentor to trainees. I received the “Mentor of the Year 2016” award from the Eastern Society for Pediatric Research ‘in recognition of sustained excellence as an educator and mentor of medical students, pediatricians-in-training, and pediatric faculty.’ I work with medical students, residents from the departments of Pediatrics and Obstetrics and Gynecology and pediatric neurology fellows from neonatal-perinatal medicine -- many of whom do not have prior exposure to research. I welcome them to work with me and introduce them to exciting opportunities in translational and clinical research. As a result, my mentees have won prestigious national and school awards as well as competitive grants from the NIH and national organizations. Seeing my mentees succeed is the most rewarding aspect of my academic career.