Event

An important goal in molecular biology is to understand at a molecular level how protein molecules perform their native functions. On the one hand, understanding the mechanism of protein function can help model how living organisms operate at a molecular level. On the other hand, understanding structure-function relationship can help develop novel reagents for use in biotechnology, research, and medicine. We apply computational (homology modeling, molecular dynamics simulation, bioinformatics) and experimental tools (biochemistry, yeast display, directed evolution, high throughput screening) to design proteins with novel molecular properties.
The current projects in the group are:
1. Engineering and application of monomeric streptavidin
2. Epitope specific binders for vaccine development
3. Novel intein mutants for in vivo and in vitro applications
4. Therapeutic peptides for the treatment of Crohn’s disease

Carol Fritsch
Email: cfritsch@buffalo.edu
Phone: 645-2842