Imaging Physics

The goal of research in imaging sciences is to advance functional imaging technologies to non-invasively image and quantify the spatiotemporal distribution of physiological, cellular and molecular events and processes for biomedical, biological, diagnostic, therapeutic, and pharmaceutical applications.

Research Areas

Instrumentation Development

  • Radiation detector and signal processing
  • Imaging systems, including PET, SPECT, and Gamma Camera
  • Multi-modality imaging, e.g. PET/CT and PET/SPECT

Data Analysis and Algorithm Development (PET/SPECT, CT, and MRI)

  • Three dimensional image reconstruction for PET, SPECT and CT
  • Query by image search of medical imaging databases
  • Medical Imaging Informatics
  • Physiological Parameter Estimates, (i.e. Blood Flow, Binding Potentials, etc.)
  • Noise Reduction Methods
  • Statistical Analysis of imaging studies.
  • Radiopharmaceutical Development
  • Small Animal Imaging (In vivo Biodistribution)


  • Combined PET/CT applications
  • PET & SPECT methodology, data processing and analysis
  • Computer aided diagnostics


Wack, David

David Wack, PhD

Associate Professor

133 Parker Hall 3435 Main St. Buffalo, NY 14214

Phone: (716) 838-5889


Yao, Rutao

Rutao Yao, PhD


105 Parker Hall 3435 Main St. Buffalo, NY 14214

Phone: (716) 829-2585