PAS 814 Hematologic Pathology and Laboratory Medicine, 4 credits

The elective is designed to provide an overview of diagnostic hematology with a focus on establishing a foundation in concepts of laboratory medicine/clinical pathology.  

The structure of the rotation involves student participation in daily sign-out in combination with supplemental didactic lectures and laboratory directorship activities.  In addition, students will attend all departmental conferences and relevant tumor board/consensus conferences occurring during their rotation.

The hematopathology service involves evaluation of peripheral blood, bone marrows, lymph nodes, other surgical pathology specimens undergoing assessment for hematologic pathology, and body fluids.

Diagnostic modalities include peripheral smear morphologic review, bone marrow aspirate/core biopsy assessment, flow cytometry, coagulation studies including mixing studies and platelet aggregation, hemoglobin electrophoresis, and body fluid morphologic review.  The role of additional ancillary testing such as cytogenetics analysis, fluorescence in situ hybridization, and molecular testing will also be established.  The student will be encouraged to utilize peer reviewed literature to expand their knowledge of key cases encountered during their rotation.

This experience is intended to emphasize practical concepts in laboratory medicine.  The clinical pathologist oversees laboratory operations to ensure appropriate ordering practices, processing of specimens, analysis of these specimens, and how the results are reported.  In addition, the director establishes quality of testing results through the review of quality control data and proficiency testing surveys.  These objectives are accomplished through the combined interaction with clinician staff and laboratory personnel.  The student will be involved in such activities occurring during their rotation.  

In addition, didactic lectures highlight concepts including laboratory accreditation and quality assurance, specimen collection and mechanisms of testing interference, variability in testing between laboratories, reference ranges, and ordering practices/utilization as they pertain to diagnostic testing in hematology.

The student will provide a 30-minute presentation at the end of the rotation, which will be centered around a case/encounter which occurs early enough for adequate preparation time.  The student will be encouraged to highlight an aspect of laboratory medicine such as those described above.  Student evaluations will be performed by the hematopathologists at Buffalo General Medical Center (Dr. Hosking and Dr. Aftab) based on the completion of the goals and objectives outlined.

Prerequisite: MS3 or MS4

Modules: TBD for Spring 2022 Blocks: TBD for Spring 2022

Number of students: 3

Course Director: TBD

Course Coordinator: Lannette Garcia