Suzanne Laychock, PhD, is investigating the cellular mechanisms regulating insulin secretion in pancreatic cells. Her group has used pancreatic cells in primary culture to develop in vitro systems that mimic aspects of Type 1 and Type 2 diabetes.
Noreen Williams, PhD, studies parasitic protozoans, including Trypanosoma brucei, which causes African sleeping sickness, transmitted by the tse-tse fly; and Trypanosoma cruzi, which causes Chagas’ disease, transmitted by the reduviid bug.
Margarita L. Dubocovich, PhD, works to elucidate melatonin’s mechanism of action and role in modulating circadian rhythms. Her lab develops novel molecules targeting melatonin receptors to treat depression, sleep disorders and cardiovascular disease.
Thomas Russo, MD, is internationally known for his work with strains of E. coli that cause infections outside the intestine and result in morbidity worldwide due to pneumonia, urinary tract infections and meningitis.
David Dietz, PhD, investigates cellular changes by which drugs “hijack” the central nervous system’s reward circuitry, causing addiction. He studies how differences in individuals’ molecular and behavioral plasticity mediate susceptibility to drug abuse and relapse.