University at Buffalo (UB)
Jennifer Hand M.D.
Jennifer Hand
M.D.
Contact Information
Patient Care
Patient Care
This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.
View this physician on UBMDProfessional Summary:
Dr. Hand is Medical Director, Pediatric Dermatology, Oishei Children’s Hospital. She holds the rank of Associate Professor, Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo. Prior to her work in Buffalo, she was section head of genetic skin disorders at Mayo Clinic in Rochester, MN where she is an emeritus Associate Professor of Dermatology, Pediatrics and Clinical Genomics. She specializes in rare genetic disorders of the skin. A strong advocate for rare disease patients, she serves on the medical and scientific advisory board for F.I.R.S.T., a national support organization for patients with Ichthyosis. She is also a Consulting Editor for GeneReviews, an on-line, free resource sponsored by the National Institute of Health. She has been a principal investigator in clinical trials including a phase 3 trial of gene therapy to treat the rare genetic skin disorder, epidermolysis bullosa.
Dr. Hand is an experienced medical educator at all levels and has been a course director for Mayo Medical School in Rochester, MN. She has given over 170 CME lectures at national and international meetings and has mentored over 60 medical students, residents, and fellows to successful careers.
She is co-author of the 3rd and latest edition of the textbook "Spitz's Genodermatoses: A full color guide to genetic skin disorders."
Education and Training:
- MD, Mayo Medical School
Employment:
- Associate Professor Emeritus, Clinical Genomics, Mayo Clinic Rochester (2022-present)
- Associate Professor Emeritus, Dermatology, Mayo Clinic Rochester (2022-present)
- Associate Professor Emeritus, Pediatrics, Mayo Clinic Rochester (2022-present)
- Clinical Associate Professor, Pediatrics, Jacobs School of Medicine and Biomedical Sciences (2022-present)
Awards and Honors:
- Top Doctors 2024 (2024)
- 2022 Top Doctors (2022)
- 2021 Top Doctors (2021)
- 2020 Top Doctors (2020)
- 2019 Top Doctors (2019)
Journal Articles:
- Miller K, McKean A, Hand J, Rackley S, Leung JG, LeMahieu A, Geske J, Bostwick JM. (2024) The occurrence of mental health symptoms in isotretinoin-treated adolescents. Pediatric dermatology (Mar).
- Maredia H, Hand JL, Tollefson MM. (2023) Pathogenesis-directed treatment of linear porokeratosis with topical cholesterol-lovastatin. Pediatric dermatology (Sep).
- Turbeville JG, Hand JL. (2023) Pediatric Cutaneous Oncology: Genodermatoses and Cancer Syndromes. Dermatologic clinics (Jan), 41(1): 175-185.
- Schlaht KM, Sas DJ, Davis DMR, Hand JL. (2022) An investigation of metabolic disturbances, including urinary stone disease, hypothyroidism, and osteoporosis in basal cell nevus syndrome. Pediatric dermatology (Sep), 39(5): 713-717.
- Boyd KP, Asumda FZ, Hand JL. (2022) Update on Clinically Relevant Genetic Testing in Pediatric Dermatology. Dermatologic clinics (Jan), 40(1): 1-8.
- Wentworth AB, Hand JL, Davis DM, Tollefson MM. (2021) Skin concerns in patients with trisomy 21 (Down syndrome): A Mayo Clinic 22-year retrospective review. Pediatric dermatology (Nov), 38 Suppl 2: 73-78.
- Afarideh M, Rodriguez Baisi KE, Davis DMR, Hand JL, Tollefson MM. (2021) Trends in utilization of non-first-line topical acne medications among children, adolescents, and adults in the United States, 2012-2016. Pediatric dermatology (Sep), 38(5): 1066-1073.
- Hines L, Lang ME, Johnson KL, Ruiz-Maldonado TM, Feldman KW, Graff AH, Hand JL. (2021) Parental neurotic excoriation injury of children: A case series of hidden physical abuse. Pediatric dermatology (Jul), 38(4): 859-863.
- Asch S, Swink SM, Vivar KL, Pickford J, Breuning L, Wassel C, Hand JL, Milstone L, Castelo-Soccio L. (2021) Use of telemedicine for ichthyosis: Patient advocacy group as conduit to expert physician advice. Pediatric dermatology (Jan), 38(1): 137-142.
- Elias AJ, Hand JL, Tollefson MM, Davis DMR. (2021) The anatomic distribution of isolated and syndrome-associated port-wine stain. Pediatric dermatology (Jan), 38(1): 77-82.
- Roberts EE, Nowsheen S, Davis DMR, Hand JL, Tollefson MM, Wetter DA. (2021) Use of spironolactone to treat acne in adolescent females. Pediatric dermatology (Jan), 38(1): 72-76.
- Kim GY, Anderson KR, Davis DMR, Hand JL, Tollefson MM. (2020) Drug reaction with eosinophilia and systemic symptoms (DRESS) in the pediatric population: A systematic review of the literature. Journal of the American Academy of Dermatology (Nov), 83(5): 1323-1330.
- Singh K, Crum OM, Davis DMR, Moran SL, Hand JL. (2020) Surgical management of pseudoainhum in loricrin keratoderma. JAAD case reports (Oct), 6(10): 1012-1015. doi:10.1016/j.jdcr.2020.07.029
- Muthusamy K, Macke EL, Klee EW, Tebben PJ, Hand JL, Hasadsri L, Marcou CA, Schimmenti LA. (2020) Congenital ichthyosis in Prader-Willi syndrome associated with maternal chromosome 15 uniparental disomy: Case report and review of autosomal recessive conditions unmasked by UPD. American journal of medical genetics. Part A (Oct), 182(10): 2442-2449.
- Ali NS, Billings ML, Tollefson MM, Davis DMR, Hand JL. (2020) Oral erosions associated with surreptitious marijuana vaping in an adolescent boy. Pediatric dermatology (Mar), 37(2): 347-349.
- Nowsheen S, Hand JL, Gibson LE, El-Azhary RA. (2019) Melanoma in a patient with previously unrecognized Birt-Hogg-Dubé syndrome. JAAD case reports (Nov), 5(11): 947-952. doi:10.1016/j.jdcr.2019.08.018
- Rolfes MC, Deyle DR, King KS, Hand JL, Graff AH, Derauf C. (2019) Fracture incidence in Ehlers-Danlos syndrome - A population-based case-control study. Child abuse & neglect (May), 91: 95-101. doi:10.1016/j.chiabu.2019.03.008
- Schoch JJ, Hunjan MK, Anderson KR, Lohse CM, Hand JL, Davis DMR, Tollefson MM. (2018) Temporal trends in prenatal risk factors for the development of infantile hemangiomas. Pediatric dermatology (Nov), 35(6): 787-791. doi:10.1111/pde.13659
- Larkin S, Blixt EK, Kumar N, Watson RE, Comfere NI, Hand JL. (2018) Lipoid proteinosis: Unfamiliar skin findings delay diagnosis. JAAD case reports (Jul), 4(6): 609-611. doi:10.1016/j.jdcr.2018.03.010
- Ma JE, Hand JL. (2017) What's new with common genetic skin disorders?. Minerva pediatrica (Aug), 69(4): 288-297.
- Eickstaedt JB, Killpack L, Tung J, Davis D, Hand JL, Tollefson MM. (2017) Psoriasis and Psoriasiform Eruptions in Pediatric Patients with Inflammatory Bowel Disease Treated with Anti-Tumor Necrosis Factor Alpha Agents. Pediatric dermatology (May), 34(3): 253-260.
- Watson KD, Schoch JJ, Beek GJ, Hand JL. (2017) Compound Heterozygosity of Dominant and Recessive COL7A Alleles in a Severely Affected Patient with a Family History of Dystrophic Epidermolysis Bullosa: Clinical Findings, Genetic Testing, and Treatment Implications. Pediatric dermatology (Mar), 34(2): 166-171.
- Johnson EF, Wetter DA, Lehman JS, Hand JL, Davis DM, Tollefson MM. (2017) Leukocytoclastic vasculitis in children: clinical characteristics, subtypes, causes and direct immunofluorescence findings of 56 biopsy-confirmed cases. Journal of the European Academy of Dermatology and Venereology : JEADV (Mar), 31(3): 544-549.
- Youssef MJ, Wolz MM, Harris MN, Richard G, Bridges AG, Wieland CN, Hand JL. (2016) Ichthyosis prematurity syndrome mimics keratitis-ichthyosis-deafness syndrome at birth: Use of electron microscopy and genetic testing. International journal of dermatology (Aug), 55(8): e454-7.
- Lazaridis KN, Schahl KA, Cousin MA, Babovic-Vuksanovic D, Riegert-Johnson DL, Gavrilova RH, McAllister TM, Lindor NM, Abraham RS, Ackerman MJ, Pichurin PN, Deyle DR, Gavrilov DK, Hand JL, Klee EW, Stephens MC, Wick MJ, Atkinson EJ, Linden DR, Ferber MJ, Wieben ED, Farrugia G, . (2016) Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience. Mayo Clinic proceedings (Mar), 91(3): 297-307.
- Anderson KR, Schoch JJ, Lohse CM, Hand JL, Davis DM, Tollefson MM. (2016) Increasing incidence of infantile hemangiomas (IH) over the past 35 years: Correlation with decreasing gestational age at birth and birth weight. Journal of the American Academy of Dermatology (Jan), 74(1): 120-6. doi:10.1016/j.jaad.2015.08.024
- Barrick BJ, Tollefson MM, Schoch JJ, McEvoy MT, Hand JL, Wieland CN, Davis DM. (2016) Penile and Scrotal Swelling: An Underrecognized Presentation of Crohn's Disease. Pediatric dermatology (Jan), 33(2): 172-7.
- Hand JL. (2015) What's new with common genetic skin disorders?. Current opinion in pediatrics (Aug), 27(4): 460-5.
- Hand JL, Runke CK, Hodge JC. (2015) The phenotype spectrum of X-linked ichthyosis identified by chromosomal microarray. Journal of the American Academy of Dermatology (Apr), 72(4): 617-27.
- Kottschade LA, Grotz TE, Dronca RS, Salomao DR, Pulido JS, Wasif N, Jakub JW, Bagaria SP, Kumar R, Kaur JS, Morita SY, Moran SL, Nguyen JT, Nguyen EC, Hand JL, Erickson LA, Brewer JD, Baum CL, Miller RC, Swanson DL, Lowe V, Markovic SN. (2014) Rare presentations of primary melanoma and special populations: a systematic review. American journal of clinical oncology (Dec), 37(6): 635-41. doi:10.1097/COC.0b013e3182868e82
- Ness MJ, Lowe GC, Davis DM, Hand JL. (2014) Narrowband ultraviolet B light in Langerhans cell histiocytosis: a case report. Pediatric dermatology (Jan), 31(1): e10-2.
- Tintle S, Alikhan A, Horner ME, Hand JL, Davis DM. (2014) Cutaneous porphyrias part II: treatment strategies. International journal of dermatology (Jan), 53(1): 3-24.
- Horner ME, Alikhan A, Tintle S, Tortorelli S, Davis DM, Hand JL. (2013) Cutaneous porphyrias part I: epidemiology, pathogenesis, presentation, diagnosis, and histopathology. International journal of dermatology (Dec), 52(12): 1464-80.
- Storan ER, McEvoy MT, Wetter DA, el-Azhary RA, Hand JL, Davis DM, Bridges AG, Camilleri MJ, Davis MD. (2013) Pediatric hospital dermatology: experience with inpatient and consult services at the Mayo Clinic. Pediatric dermatology (Jan), 30(4): 433-7.
- Dabade TS, Davis DM, Wetter DA, Hand JL, McEvoy MT, Pittelkow MR, el-Azhary RA, Davis MD. (2012) Wet dressing therapy in conjunction with topical corticosteroids is effective for rapid control of severe pediatric atopic dermatitis: experience with 218 patients over 30 years at Mayo Clinic. Journal of the American Academy of Dermatology (Jul), 67(1): 100-6.
- Hand JL. (2012) Retinoic acid: a familiar teratogen. Pediatric dermatology (Jan), 29(6): 774-6.
- Brick K, Hand JL, Frankel AS, Siegel DH, Thomas KB, El-Azhary R, Krol A. (2012) Epidermolysis bullosa pruriginosa: further clarification of the phenotype. Pediatric dermatology (Jan), 29(6): 732-7.
- Podjasek JO, Hand JL. (2011) Marie-Unna hereditary hypotrichosis: case report and review of the literature. Pediatric dermatology (Jan), 28(2): 202-4.
- Wetter DA, Davis MD, Hand JL. (2008) Acute paralysis in a 17-year-old man with subtle cutaneous vascular malformations: an unusual case of Cobb syndrome. Journal of the European Academy of Dermatology and Venereology : JEADV (Apr), 22(4): 525-6.
- Ayo DS, Aughenbaugh GL, Yi ES, Hand JL, Ryu JH. (2007) Cystic lung disease in Birt-Hogg-Dube syndrome. Chest (Aug), 132(2): 679-84.
- Markovic SN, Erickson LA, Rao RD, Weenig RH, Pockaj BA, Bardia A, Vachon CM, Schild SE, McWilliams RR, Hand JL, Laman SD, Kottschade LA, Maples WJ, Pittelkow MR, Pulido JS, Cameron JD, Creagan ET, . (2007) Malignant melanoma in the 21st century, part 2: staging, prognosis, and treatment. Mayo Clinic proceedings (Apr), 82(4): 490-513.
- Markovic SN, Erickson LA, Rao RD, Weenig RH, Pockaj BA, Bardia A, Vachon CM, Schild SE, McWilliams RR, Hand JL, Laman SD, Kottschade LA, Maples WJ, Pittelkow MR, Pulido JS, Cameron JD, Creagan ET, . (2007) Malignant melanoma in the 21st century, part 1: epidemiology, risk factors, screening, prevention, and diagnosis. Mayo Clinic proceedings (Mar), 82(3): 364-80.
- Mensink KA, Hand JL. (2006) Autosomal recessive inheritance: an updated review. Pediatric dermatology (Jan), 23(4): 404-9.
- Kuhl J, Davis MD, Kalaaji AN, Kamath PS, Hand JL, Peine CJ. (2004) Skin signs as the presenting manifestation of severe nutritional deficiency: report of 2 cases. Archives of dermatology (May), 140(5): 521-4.
- Hand JL, Rogers RS. (2003) Oral manifestations of genodermatoses. Dermatologic clinics (Jan), 21(1): 183-94.
Books and Book Chapters:
- Hand JL, Spitz JL, Turbeville, JG. (2024) Spitz’s Genodermatoses. A full color guide. Wolters-Klewer.
- Torrelo A. Hernandez-Martin A, Lucky A, Pope E, Siegfried EC, Silverman RA, Wiss K. (2022) 4.7 Chromosomal Disorders. In: Schachner and Hansen’s Pediatric Dermatology 5th Edition. Jaypee Brothers Medical Publication
- Bolognia JL, Schaffer JV, Cerroni L. Callen JP, Cowen EW, Duncan KO, Hruza GJ et al. (1900) 54. Basic Principles of Genetics. In: Dermatology, Fifth Edition. Elsevier
Professional Memberships:
- Pediatric Dermatology Research Alliance (PeDRA) Vascular Anomlies Group; National working group for study of vascular anomalies (2024)
- American Medical Association
- American College of Medical Genetics
Presentations:
- "Back to Basics-The Physical Exam is the Cornerstone of Precision Medicine: Visual Exam of the Hair & Nails: High Yield Clues for a Unifying Diagnosis" American College of Medical Genetics Annual Meeting 2024 (2024)
- "Genodermatoses 101: Update on Genetic Testing for the Dermatologist" American Academy of Dermatology Annual Meeting 2024 (2024)
- "Think like an Expert about Ichthyosis: Case Presentation" American Academy of Dermatology Annual Meeting 2024 (2024)
- "Genodermatoses" Northwestern University Department of Dermatology; Annual Genodermatoses Conference (2024)
- "Hair and Nails: High Yield Clues for a Unifying Diagnosis" University at Buffalo Pediatrics Grand Rounds (2024)
- "Rare Disease Resources for Pediatric Dermatology Investigators" 2022 Pediatric Dermatology Research Alliance (2023)
- "Genetic Testing: What the Dermatologist Needs to Know" American Academy of Dermatology Annual Meeting 2023 (2023)
- "Genodermatoses: Disorders of the Dermis" Genodermatoses 2023 presented by Northwestern University (2023)
- "Neonatal Rashes" University at Buffalo Pediatrics Grand Rounds (2023)
- "Dermatology Stories: (Life) Lessons Learned" 33rd Biennial Dermatology Symposium: The O’Leary Meeting 2022 hosted by Mayo Clinic (2022)
- "Vascular Anomalies: Presentation from Buffalo Site" 2022 Oncology Thruway Collaboration Meeting (2022)
- "Genetic Disorders: Presentations from Infancy to Adulthood" American Academy of Dermatology 72nd Annual Meeting (2014)
Service Activities:
- Case Presentation faculty mentor: Olmsted syndrome; Linear porokeratosis; Minnesota Dermatological Society (2022)
- 33rd Biennial Dermatology Symposium: The O’Leary Meeting hosted by Mayo Clinic; Introduction of Paul A. O’Leary Lecturer (2022)
- Medical Director, Oishei Children’s Hospital Outpatient Dermatology; Medical Director (2022–present)
- National Organization of Rare Disease (NORD), Centers of Excellence Medical Professional Education Working Group; Rare Disease Centers of Excellence Medical Professional Education Working Group (2022–present)
- Journal of Pediatric Dermatology; Editorial Board Member (2018–present)
- Society for Pediatric Dermatology/ Awards and Grants Committee; Committee Chair (2018–2021)
- New England Journal of Medicine; Reviewer (2014–present)