Stephen B. Edge MD, FACS, FASCO

Stephen Edge

Stephen B. Edge


Department of Surgery

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus

Oncology; Surgery

Contact Information
Roswell Park Cancer Institute
Elm & Carlton Streets
Department of Surgery
Buffalo, New York 14263
Phone: (716) 845-2918
Fax: (716) 845-1668

Professional Summary:

Research and Professional Goals:
1. Clilnical research program: Our work at Roswell Park Cancer Institute focuses on translational research in breast cancer diagnosis and treatment, including collaborations with other clinicians and scientists in biological markers of cancer and cancer progression.
2. Health Services Research: Using a variety of data sources, we are working on methods to define and improve the quality of cancer care. The models used for this work include administrative claims data from regional payers, and multi institutional databases through national consortiums.
3. Clinical activities: We maintain a high volume, multidisciplinary program in breast cancer diagnosis and treatment at Roswell Park Cancer Institute. Teaching, clinical trials and translational research are integrated into this program at all levels.

Education and Training:

  • Residency, University Hospitals of Cleveland, Case Western Reserve Univ. (1986)
  • Fellowship, National Cancer Institute, Surgery Branch, Bethesda (1984)
  • Internship, University Hospitals of Cleveland, Case Western Reserve University Surgery Program, Cleveland (1980)
  • MD, Case Western Reserve University, Cleveland (1979)
  • BA, Tufts University, Medford (1975)
  • Residency, University Hospitals of Cleveland, Case Western Reserve University Surgery Program, Cleveland

Journal Articles:

See all (258 more)

Books and Book Chapters:

  • Xu Y, Edge SB, Hurd TC, Repasky E, Slocum HK. (1900) Implantation and characterization of human breast carcinomas in SCID mice.


  • Wilkinson NW, Shahryarinejad A, Winston JS, Watroba N, Edge SB. (2003) Concordance with breast cancer pathology reporting practice guidelines: Community-wide practice. Journal of the American College of Surgeons (in press – accepted August, 2002, Elsevier Science Journals Reference Number ACS2106 - anticipated publication December, 2002), (Jan) 38-43
  • Proulx GM, Loree T, Edge S, Hurd T, Stomper P. (2002) Outcome with post mastectomy radiation with TRAM flap breast reconstruction. American Surgeon 2002, (Jan) 410-413
  • Edge SB, Gold K, Berg CD, Meropol NJ, Tsangaris TN, Gray L, Petersen BM, Hwang YT, Mandelblatt JS. (2002) Patient and provider characteristics affecting use of axillary dissection in older women with Stage I/II breast cancer. Cancer 2002, (Jan) 2534-2541
  • McKee M, Cropp M, Hyland A, Watroba N, McKinely B, Edge SB. (2002) Provider case volume and outcome in the evaluation and treatment of mammogram-detected breast cancer. Cancer 2002, (Jan) 704-712
  • Singletary SE, Allred C, Ashley P, Bassett LW, Berry D, Bland KI, Borgen PI, Clark G, Edge SB, Hayes DF, Hughes LL, Hutter RVP, Morrow M, Page DL, Recht A, Theriault RL,Thor A, Weaver DL, Wieand HS, Greene FL. (2002) Revision of the American Joint Committee on Cancer Staging System for Breast Cancer. J Clin Oncol 2002, (Jan) 3628-3636
  • Proulx GM, Hurd T, Lee RJ, Stomper PC, Podgorsak MB, Edge SB. (2001) Intraoperative radiation therapy (IORT) to the tumor bed only for breast cancer: technique and outcome. Radiation Oncology 2001, (Jan) 35-41
  • Yates J, Edge SB. (1999) Evaluating guidelines: an important step in improving cancer care. Oncology (Huntingt) 1999, (Jan) 523-528
  • Edge SB, Fritz A, Clutter GG, Page DL, Watkins S, Blankenship C, Douglas K, Fleming I. (1999) A unified cancer stage data collection system: Preliminary report from the Collaborative Stage Task Force / American Joint Committee on Cancer. Journal of Registry Management 1999, (Jan) 57-61
  • Winer EP, Hudis C, Harold J. Burstein HJ, Chlebowski RT, Ingle JN, Edge SB, Mamounas EP, Gralow J, Goldstein LJ, Pritchard KI, Braun S, Cobleigh MA, Langer AS, Perotti J, Powles, Whelan TJ, Browman GP. (1900) American Society of Clinical Oncology Technology Assessment on the Use of Aromatase Inhibitors as Adjuvant Therapy for Women with Hormone Receptor Positive Breast Cancer: Status Report 2002. J Clin Oncol. 2002, (Jan) 3317-3327
  • Swede H, Moysich KB, Winston JS, Hurd TC, Edge SB, Gutierriz-Romero M, Brooks JSJ, Michalek AM. (1900) Variation of prognostic significance of HER2 expression in breast cancer according to tumor size. The Breast Journal (in press – Manuscript #21124), (Jan)
  • Yarussi A, Sands R, Edge SB, Lema MJ, deLeon-Casasola OA. (1900) Evaluation of peripheral morphine analgesia for lumpectomy and axillary node dissection: A randomized, double-blinded placebo-controlled study. Regional Anesthesia and Pain Medicine. 1999, (Jan) 142-145
  • Edge SB. (1900) Evidence-based breast cancer staging (editorial). Breast Diseases: A Year Book Quarterly 2001, (Jan) 257-258
  • Carlson RW, Anderson BO, Bensinger W, Cox C. Davidson NE, Edge SB, Farrar WB, Goldstein LJ, Gradishar WJ, Lichter AS, McCormick B, Nabell LM, Reed EC, Silver SM, Smith ML, Somlo G, Theriault RL, Winer EP. (1900) National Cancer Center Network Breast Cancer Guidelines. Oncology (Huntington) 1999, (Jan) 41-66
  • Mandelblatt JS, Edge SB, Meropol NJ, Senie R, Tsangaris T, Grey L, Peterson B, Zhong A, Hwang YT, Weeks JC. (1900) Sequelae of axillary node dissection in older women with localized breast cancer. Cancer (in press – accepted June, 2002 – Manuscript #C-0628-02), (Jan)
  • Mandelblatt JS, Hadley J, Kerner JF, Schulman KA, Gold K, Dunmore-Griffeth J, Edge S, Guadagnoli E, Lynch JJ, Meropol NJ, Weeks JC, Winn R. (1900) Patterns of breast cancer treatment in older women - Patient preference and clinical and physician influence. Cancer 2000, (Jan) 561-573
See all (5 more)


  • "3. Hemorrhage Without Tissue Trauma Produces Immunosuppression." Annual Meeting of the Society of University Surgeons,; ; (Residenß' Meeting). (1986)
  • "Parenchymal and Non-Parenchymal Liver Cell Response to Regenerating Liver Cytosol." American College of Surgeons (1985)
  • "In Vitro Liver Regeneration." Grand Rounds; ; Yale University School of Medicine (1984)

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Contact Information

Roswell Park Cancer Institute
Elm & Carlton Streets
Department of Surgery
Buffalo, New York 14263
Phone: (716) 845-2918
Fax: (716) 845-1668