Robert D. Baker MD, PhD
Robert D. Baker
MD, PhD
Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Pediatric Gastroenterology; Pediatrics
Education and Training:
- Fellowship, Pediatric Gastroenterology, Boston Children‘s Hospital (1984)
- PhD, Nutritional Biochemistry and Metabolism, Massachusetts Institute of Technology (1984)
- Fellowship, Gastroenterology and Nutrition, Boston Children's Hospital (1982)
- Fellowship, Nutrition, Boston Children‘s Hospital (1982)
- Residency, Pediatrics, University at Buffalo (1975)
- Internship, Pediatrics, University at Buffalo (1973)
- MD, Medicine, Temple University School of Medicine (1972)
- BA, English, Harvard University, Cum Laude (1968)
Employment:
- Professor with Tenure, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2003-present)
- Attending Physician, Digestive Diseases and Nutrition Center, Oishei Children‘s Hospital (2000–2018)
- Division Co-Chief, Gastroenterology, UBMD Pediatrics (2000–2018)
- Medical Director, Variety Four Procedure Area and Tanner Eight Infusion Area, Women and Children‘s Hospital of Buffalo (2000–2011)
- Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2000–2003)
- Director, Cystic Fibrosis Center, Cystic Fibrosis Center, Medical University of South Carolina (1995–2000)
- Associate Professor, Department of Pediatrics and College of Graduate Studies, Medical University of South Carolina (1993–2000)
- Co-Director, Pediatric Gastroenterology and Nutrition, Medical University of South Carolina (1993–2000)
- Assistant Professor, Pediatrics, University of Massachusetts Medical Center (1986–1993)
- Co-Director, Pediatric Gastroenterology and Nutrition, University of Massachusetts Medical Center (1986–1993)
Awards and Honors:
- None (2024)
- American Physiological Society: Distinction in Scholarship - 'Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis' (2018)
- Hepatology (Journal of the American Association for the Study of Liver Diseases): 2nd Most Cited Paper Published in 2013 (2014)
- Best Doctors in America (1998-2012)
- Buffalo Spree Magazine: Top Doctors in Western New York (2013-2019)
- Castle Connolly: America's Top Doctors (2016-2020)
- Daniel James Gasparini Research Fellow in Hepatology (1985-1986)
- none
Research Expertise:
- Cystic fibrosis
- Gastroesophageal reflux
- Hepatitis
- Inflammatory bowel disease
- Liver disease: Non-alcoholic steatohepatitis
- Nutrition
Grants and Sponsored Research:
- January 2012–February 2015
A Multicenter, Open Label Study to Evaluate the Safety of Entocort TM EC for the Maintenance Treatment of Crohn‘s Disease in Pediatric Subjects Aged 5 to 17 Years, Inclusive
AstraZeneca Pharmaceuticals
Role: Principal Investigator
$16,199 - January 2012–February 2015
A Multicenter, Open Label Study to Evaluate the Safety of Entocort TM EC for the Treatment of Crohn‘s Disease in Pediatric Subjects Aged 5 to 17 Years, Inclusive
AstraZeneca Pharmaceuticals
Role: Principal Investigator
$38,547
Journal Articles:
- Zhu L, Baker SS, Liu W, Tao MH, Patel R, Nowak NJ, Baker RD. (2011) Lipid in the livers of adolescents with nonalcoholic steatohepatitis: combined effects of pathways on steatosis. Metabolism (Jul), 60(7): 1001-1011.
- Sayej WN, Alkhouri RH, Baker RD, Patel R, Baker SS. (2011) Esophagitis in children with celiac disease. ISRN Gastroenterol (Jan), 2011.
- Wanzer MB, Wojtasczyk AM, Schimert J, Missert L, Baker SS, Baker RD, Dunkle B. (2010) Enhancing the "informed" in informed consent: a pilot test of a multimedia presentation. Health Commun (Jun), 25(4): 365-374.
- Lin H, Zhu L, Baker SS, Baker RD, Lee T. (2020) Secreted phosphoglucose isomerase is a novel biomarker of nonalcoholic fatty liver in mice and humans. Biochem Biophys Res Commun (Sep), 529(4): 1101-1105.
- Moya DA, Nugent CA, Baker RD, Baker SS. (2020) Celiac Disease Nutritional Status and Poor Adherence to Follow-up. Clin Pediatr (Phila) (Jun), 59(7): 649-655.
- Baker SS, Baker RD. (2020) Gut Microbiota and Liver Injury (II): Chronic Liver Injury. Adv Exp Med Biol (Jan), 1238: 39-54.
- Yang L, Tang S, Baker SS, Arijs I, Liu W, Alkhouri R, Lan P, Baker RD, Tang Z, Ji G, Rutgeerts P, Vermeire S, Zhu R, Zhu L. (2019) Corrigendum: Difference in Pathomechanism Between Crohn's Disease and Ulcerative Colitis Revealed by Colon Transcriptome. Inflamm Bowel Dis (Oct), 25(11): 154-154.
- Yang L, Tang S, Baker SS, Arijs I, Liu W, Alkhouri R, Lan P, Baker RD, Tang Z, Ji G, Rutgeerts P, Vermeire S, Zhu R, Zhu L. (2019) Difference in Pathomechanism Between Crohn's Disease and Ulcerative Colitis Revealed by Colon Transcriptome. Inflamm Bowel Dis (Jan), 25(4): 722-731.
- Jiao N, Baker SS, Chapa-Rodriguez A, Liu W, Nugent CA, Tsompana M, Mastrandrea L, Buck MJ, Baker RD, Genco RJ, Zhu R, Zhu L. (2018) Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD. Gut (Oct), 67(10): 1881-1891.
- Aljomah G, Baker SS, Schmidt K, Alkhouri RH, Kozielski R, Zhu L, Baker RD. (2018) Anemia in Pediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr (Sep), 67(3): 351-355.
Books and Book Chapters:
- RD Baker. (2024) Gastroenterology. In: Pediatric Board Study Guide: A Last Minute Review. Springer Nature
- Baker RD, Baker SS. (2015) In: "Infant and Toddler Nutrition". Elsevier
- Baker RD. (2014) In: "Viral Hepatitis". CRC Press, 314-328.
- Baker RD, Baker SS. (2010) In: "Nutrition". McGraw-Hill
- Baker SS, Baker RD. (2009) In: "Infant and Toddler Nutrition". Elsevier Science
- Baker SS, Baker RD, Davis AM. (2006) Pediatric Nutrition Support. Jones and Bartlett Publishers.
- Baker SS, Baker RD. (2006) In: "Macronutrients". Jones and Bartlett
- Baker SS, Baker RD. (2005) In: "Hyperalimentation". Elsevier Mosby, 1890-1895.
- Baker SS, Baker RD. (2005) In: "Infant and Toddler Nutrition". Elsevier Science
- Baker SS, Baker RD. (2004) In: "Parenteral Nutrition". BC Decker, Inc., 1958-1980.
Abstracts:
- Jiao N, Baker SS, Chapa Rodriguez A, Liu W, Nugent CA, Tsompana M, Mastrandrea LD, Buck M, Baker RD, Genco RJ, Zhu R, Zhu L. (2017) Suppressed Hepatic Bile Acid Signaling Despite Elevated Production of Primary and Secondary Bile Acids in NAFLD. Gastroenterology, (Apr) S1068-S1068
- Bhatia T, Baker SS, Liu W, Chapa-Rodriguez A, Baker RD, Lee TC, Zhu L. (2016) Secretory Frizzled Receptor Proteins and Liver Fibrosis in Non-Alcoholic Fatty Liver Disease. Hepatology, (Nov) 146A-147A
- Wang B, Baker SS, Liu W, Wang H, Baker RD, Ross C, Zhu L. (2016) Retinoic Acid as a Factor in the Pathogenesis of NAFLD. Hepatology, (Nov) 805A-805A
- Abdou RM, Baker RD, Moya DA, Baker SS. (2016) Portal Inflammation and Fibrosis are More Advanced in Younger Children with Non-Alcoholic Fatty Liver Disease. Hepatology, (Nov) 277A-277A
- Feng Q, Baker SS, Liu W, Arbizu RA, Aljomah G, Khatib M, Nugent CA, Baker RD, Hu Y, Zhu L. (2014) Combination of Geniposide and Chlorogenic Acid May Reverse NASH Pathogenesis by Improving Gut Barrier Function. Hepatology, (Oct)
- Patel RA, Baker SS, Liu W, Desai S, Alkhouri RH, Kozielski R, Mastrandrea LD, Sarfraz S, Cai W, Vlassara H, Patel MS, Baker RD, Zhu L. (2012) Effect of Dietary Advanced Glycation End Products on Mouse Liver. PLoS ONE, (Apr)
- Nugent CA, Martin P, Ma C, Baker RD, Baker SS. (2012) Impact of Psychological Distress in Relation to the Severity of Inflammatory Bowel Disease in an Adolescent Population. J Pediatr Gastroenterol Nutr, (Jan) 90-90
- Sayej WN, Patel R, Baker RD, Baker SS. (2009) Terminal Ileal Disease and Positive ASCA IgA and IgG may be Predictors for Development of Phlegmons in Children with Crohn Disease. J Pediatr Gastroenterol Nutr, (Jan) E62-E62
- Sayej WN, Knight PK III, Baker RD, Baker SS. (2009) CLCX-10 is a Potential Maker for Autoimmune Hepatitis. J Pediatr Gastroenterol Nutr, (Jan) E76-E76
- Sayej WN, Patel RA, Baker RD, Tron E, Crawley AM, Baker SS. (2008) High Dose Acid Suppression Distinguishes Severe Reflux Esophagitis from Eosinophilic Esophagitis. Gastroenterol, (Jan) A58-A58
Professional Memberships:
- American Academy of Pediatrics
- American Gastroenterological Association
- American Pediatric Society
- American Society for Parenteral and Enteral Nutrition
- Buffalo Pediatric Society
- Central New York Pediatric Society
- North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
- Western New York GI and Liver Society
Presentations:
- "A Rare Case of Gallbladder and Common Bile Duct Capillary Hemangioma in a Toddler" Annual Meeting; North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (2017)
- "Steatosis, Portal Inflammation and Fibrosis are More Advanced in Younger Children with Non-Alcoholic Fatty Liver Disease" The Liver Meeting; American Association for the Study of Liver Diseases (2017)
- "Hepatic Falvin Monooxygenase 3 (FMO3) is Highly Upregulated in Nonalcoholic Fatty Liver Disease (NAFLD)" Digestive Disease Week; American Gastroenterological Association (2017)
- "High-Fat Diet Increases Clostridium Clusters XIVa in Obese Rodents: A Meta-Analysis" Digestive Disease Week; American Gastroenterological Association (2017)
- "Suppressed Hepatic Bile Acid Signaling Despite Elevated Production of Primary and Secondary Bile Acids in NAFLD" Digestive Disease Week; American Gastroenterological Association (2017)
- "Portal Inflammation and Fibrosis are More Advanced in Younger Children with Non-Alcoholic Fatty Liver Disease" The Liver Meeting; American Association for the Study of Liver Diseases (2016)
- "Retinoic Acid as a Factor in the Pathogenesis of NAFLD" The Liver Meeting; American Association for the Study of Liver Diseases (2016)
- "Secretory Frizzled Receptor Proteins and Liver Fibrosis in Non-Alcoholic Fatty Liver Disease" The Liver Meeting; American Association for the Study of Liver Diseases (2016)
- "A Child with Apnea: Looking Beyond Reflux" Annual Meeting; North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (2016)
- "Colonic Lymphoma Presenting as Abdominal Pain" Annual Meeting; North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (2016)
Service Activities:
- Write and submit potential questions for Pediatric Boards.; Exam Question Writer, American Academy of Pediatrics, EQIPP (2024)
- review manuscript submissions. Suggest and decide on topics for future. Write review papers for publication. Submit blogs.; editor (2014–2022)
- University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Ad Hoc Committee on Promotions, Non-Tenure Track; Committee Member (2011–present)
- Women and Children‘s Hospital of Buffalo: User Group 7 - Infusion Area Planning Group; Member (2011–present)
- Women and Children‘s Hospital of Buffalo: User Group - Ambulatory Surgery Area Planning Group; Member (2011–present)
- PNAS Session (Vancouver, BC); Moderator (2010)
- Women and Children‘s Hospital of Buffalo: PSPC Ambulatory Surgery Center Planning Subcommittee; Committee Member (2010–present)
- Great Lakes Health: Professional Steering Committee - GI Subcommittee; Committee Member (2009–2010)
- American Pediatric Society; Reviewer (2009)
- Belgian Cystic Fibrosis Association; Grant Reviewer (2008)
- Cystic Fibrosis Foundation: Data Safety Monitoring Board; Board Member (2006–2013)
- University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Continuing Education Committee; Committee Member (2006–present)
- American Academy of Pediatrics: Executive Committee on Gastroenterology and Nutrition; Committee Member (2005–2015)
- Kaleida Health: Pediatric Gastrointestinal Transplant Committee; Chair (2003–2010)
- Women and Children‘s Hospital of Buffalo: Operating Room Block Booking Committee; Committee Member (2003–present)
- Federal Drug Administration: Contaminants and Natural Toxicants Subcommittee; Committee Member (2003–present)
- Federal Drug Administration: Food Advisory Committee (Infant Formulas); Committee Member (2002–2007)
- American Academy of Pediatrics: Committee on Nutrition/Canadian Pediatric Society: Nutrition Committee; National Liaison (2002–2007)
- University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Faculty Council; Member (2002–2005)
- American Academy of Pediatrics: Committee on Nutrition Sections Representative (2001–2007)
- Cystic Fibrosis Foundation/NASPGHAN: Consensus Conference on Nutrition and Cystic Fibrosis Co-Organizer (2001)
- University at Buffalo Associates: Clinical Practice Committee; Committee Member (2001–present)
- American College of Graduate Medical Education: Pediatric Gastroenterology and Nutrition; Director (2001–present)
- Children‘s Digestive Health and Nutrition Foundation: Committee on Treatment of GERD, Children are Not Small Adults: Current Knowledge/Future Research; Committee Member (2000–2007)
- Kaleida Health: Staff Credentials Committee; Committee Member (2000–2004)
- University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Resident Recruitment Committee; Committee Member (2000–present)
- UBMD Pediatrics: Billing Committee; Committee Member (2000–present)
- University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Resident GI Rotations; Teacher (2000–present)
- Journal of Pediatric Gastroenterology and Nutrition: News and Views, Nutrition; Editor (1998–2004)
- NASPGHAN: Committee to Establish Guidelines for Gastroesophageal Reflux Pediatrics; Committee Member (1997–2000)
- Medical University of South Carolina: Pediatric Resident GI Rotations; Teacher (1996–2000)
- Medical University of South Carolina: Quality Improvement Committee; Committee Member (1995–2000)
- American College of Graduate Medical Education: Pediatric Gastroenterology and Nutrition; Director (1995–2000)
- Medical University of South Carolina; Advisory Board (1995–1998)
- Medical University of South Carolina: Continuing Education Committee; Committee Member (1994–2000)
- Medical University of South Carolina: Children‘s Hospital Executive Committee; Committee Member (1994–2000)
- University of Massachusetts Medical Center: Human Subjects Committee; Committee Member (1989–1993)
- University of Massachusetts Medical Center: Medical Staff Credentials Committee; Committee Member (1988–1992)
- University of Massachusetts Medical School: Pediatric Resident GI Rotations; Teacher (1986–1993)
- Pediatrics (Journal of the American Academy of Pediatrics); Reviewer (1985–present)
- Journal of Pediatrics; Reviewer (1985–present)
- Journal of the National Cancer Institute; Reviewer (1985–present)
- Journal of Biochemical Pharmacology; Reviewer (1985–present)
- Journal of Clinical Nutrition; Reviewer (1985–present)
- Journal of Digestive Diseases in Science; Reviewer (1985–present)
- Journal of Gastroenterology; Reviewer (1985–present)
- Journal of Parenteral and Enteral Nutrition; Reviewer (1985–present)
- Journal of Pediatric Gastroenterology and Nutrition; Reviewer (1985–present)
- Southern Pediatric Gut Club; Co-Founder
- New England Journal of Medicine; Reviewer