Anurag K. Singh MD

Anurag Singh

Anurag K. Singh
MD

Professor, Director of Radiation Research

Department of Radiation Oncology

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Cancer Treatment and Prevention; Immunology; Radiation Medicine; Radiation Oncology

Contact Information
Roswell Park Cancer Institute
Dept. of Radiation Medicine
Elm and Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-3218
Fax: (716) 845-8254
as277@buffalo.edu


Patient Care

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Education and Training:

  • Residency, Radiation Oncology, Washington University in Saint Louis School of Medicine, Mallinckrodt Institute of Radiology (2004)
  • Internship, Internal Medicine, Washington University in Saint Louis School of Medicine, Barnes-Jewish Hospital (2000)
  • MD, Medicine, Washington University in Saint Louis School of Medicine (1999)
  • BS, Molecular Biophysics and Biochemistry, Yale University (1995)

Employment:

  • Professor, Roswell Park Cancer Institute, University at Buffalo (2012-present)
  • Associate Professor, Roswell Park Cancer Institute, University at Buffalo (2007–2012)
  • Attending Physician, Radiation Oncology Branch, National Cancer Institute (2004–2007)

Awards and Honors:

  • ASTRO Basic/Translational Science Abstract Award (2017)
  • Walter T. Murphy Educator of the Year Award (2016)
  • Top Doctors of Western New York (2016)
  • Top Doctors of Western New York (2015)
  • Top Doctors of Western New York (2014)
  • Top Doctors of Western New York (2013)
  • Outstanding Accreditation Award from University at Buffalo (2011)
  • Educator of the Year (2010)
  • Educator of the Year (2009)
  • CaPSure Mentor (for Nicole SImone) (2006)
  • Magna Cum Laude Graduate (1995)

Research Expertise:

  • Imaging Cancer: Use of imaging for improved staging and/or delineation of tumors.
  • Novel Radiation Enhancers: Novel agents used in combination with radiation therapy.
  • Radiation Protectors, Quality of Life: Novel Agents
  • Stereotactic Body Radiation Therapy (SBRT): SBRT is a novel method of delivering extremely high radiation doses to very small areas. I have designed, implemented, and run several clinical SBRT trials.

Grants and Sponsored Research:

  • April 2016–March 2021
    Large heat shock proteins and their role in cancer therapy
    National Cancer Institute
    Role: Co-Investigator
    $1,125,000
  • April 2016–March 2020
    Non-invasive assessment of salivary gland function: translational studies
    National Cancer Institute
    Role: Co-Investigator
    $1,569,224
  • May 2014–April 2019
    Cancer Center Support Grant
    National Cancer Institute
    Role: Co-Investigator
    $19,000,000
  • May 2014–February 2019
    NCI National Clinical Trials Network- Network Lead Academic Participating Site Grant
    National Cancer Institute
    Role: Co-Investigator
    $1,813,900
  • September 2017–August 2018
    Low-cost Mobile Oral Cancer Screening for Low Resource Setting
    Liang, Univeristy of Arizona
    Role: Co-Investigator
    $1,125,000
  • April 2016–April 2017
    Utilizing Radiation to Enhance the Immune Response in SCCHN
    Roswell Park Alliance Foundation
    Role: Principal Investigator
    $50,000
  • April 2016–April 2017
    Utilizing Radiation to Enhance the Immune Response in Lung Cancer
    Roswell Park Alliance Foundation
    Role: Principal Investigator
    $25,000
  • December 2010–December 2015
    A Phase 2 Placebo-Controlled Randomized Study of the Effect of Samital on Incidence, Duration and Severity of Oropharyngeal Mucositis Induced by Chemoradiation for Squamous Cell Carcinoma of the Head and Neck (SCCHN)
    Indena SPA
    Role: Principal Investigator
    $1,600,478
  • October 2011–September 2014
    Louis Sklarow Memorial Trust
    Louis Sklarow Memorial Trust
    Role: Co-Investigator
    $40,000
  • April 2008–June 2012
    A Phase II Randomized Study of 2 Sterotactic Body Radiation Therapy (SBRT) Regimens for Medically Inoperable Patients with Node Negative, Peripheral Non-Small Cell Lung Cancer
    Roswell Park Alliance Foundation
    Role: Co-Investigator
    $97,963
  • July 2009–December 2011
    Hybrid Imaging Technique (HIT) Guided Biopsy to Map Prostatic Adenocarcinoma in Patients Undergoing Prostatectomy
    Roswell Park Alliance Foundation
    Role: Co-Investigator
    $99,956
  • July 2005–July 2007
    Development of Prostate and Breast Cancer magnetic Resonance Imaging and Image Guided Therapy
    Center for Clinical Research, NCI Intramural Grant
    Role: Principal Investigator
    $280,000
  • April 2012
    Body Warming to Alter (thermo) Regulation and the Microenvironment (B-WARM) Therapy: A Pilot Study
    Braun Foundation
    Role: Principal Investigator
    $75,000
  • September 2007
    MR Imaging to Stratify Prostate Cancer Progression Risk in Patients on Active Surveillance
    Roswell Park Alliance Foundation
    Role: Principal Investigator
    $100,000
See all (4 more)

Journal Articles:

See all (55 more)

Evaluative Studies and Case Reports:


Presentations:

  • "A Pilot Study of Stereotactic Body Radiation Therapy Combined with Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma" ASTRO Annual Meeting, ASTRO, Oral Presentation, Radiation Oncologist (2017)
  • "Advances in Conformal Radiation Therapy" International Association of Oral Oncology (2017)
  • "Management of Radaition Induced Xerostomia" International Association of Oral Oncology (2017)
  • "Reirradiation in Head and Neck Cancer Workshop: Cumulative Toxicity Assessment and Management" International Association of Oral Oncology (2017)
  • "Tobacco Cessation and Oral Leukoplakia" International Association of Oral Oncology (2017)
  • "Plenary Session: A Phase 2 Randomized Study of 2 Stereotactic Body Radiation Therapy (SBRT) Regimens for Medically Inoperable Patients with Node-Negative, Peripheral Non-Small Cell Lung Cancer" Multidisciplinary Thoracic Cancers Symposium (2017)
  • "How does SBRT work? Review of new clinical trials" Therapists and Dosimetrists Conference, Roswell Park Cancer Institute, Radiation Therapists/Medical Dosimetrist (2016)
  • "Stereotactic Body Radiation Therapy, Immunity & Toxicity" Visiting Professor, University of Rochester, Radiation Oncology Residents (2015)
  • "IMRT, VMAT, IGRT & SBRT: An Inroduction To the Alphabet Soup of Radiation Oncology" NRG Oncology Semi-Annual Meeting, NRG Oncology, Oncologist (2015)
  • "SBRT and Immunity: Waiting for the Abscopal Effect" Visiting Professor, University of California, Radiation Oncology Residents (2015)
  • "Oral Mucositis in Head and Neck Cancer Oral Cancer: Early Detection, Management, and Rehabilitation." , Roswell Park Cancer Institute (2014)
  • "New Hope After 40 Years of Futility In Lung Cancer: Advances in Surgery, Targeted Therapy, and Role for SBRT" Therapists and Dosimetrists Conf., Roswell Park Cancer Institute, Radiation Therapists/Medical Dosimetrist (2013)
  • "Lung Cancer Management: Radiation Medicine" RPCI- Lung Cancer 2011 Update, Roswell Park Cancer Institute (2011)
  • "New directions in SBRT: Can we move beyond just peripheral, early stage lung tumors?" Therapists and Dosimetrists Conference, Roswell Park Cancer Institute, Radiation Medicine (2010)
  • "Panel Discussant: Localized and Locally Advanced Lung Cancer" Second Niagara Lung Cancer Symposium, Roswell Park Cancer Institute (2010)
  • "Beyond Perfexion: Extra-cranial SBRT at RPCI" Upstate New York Society for Therapeutic Radiation Oncology (UNYSTRO) Annual Conference, UNYSTRO (2010)
  • "Review of Lung, H&N, and Renal SBRT: Possibilities and Pitfalls" National Cancer Institute Visiting Professor Series, National Cancer Institute, National Cancer Institute (2010)
  • "Improving Radiation Therapy Outcomes, The Biologic Rationale fors: protectors, sensitizers, and SBRT" Therapists and Dosimetrists Conference, Roswell Park Cancer Institute, Radiation Medicine (2009)
  • "Alphabet Soup: IMRT, SBRT and other Advances in Radiation Therapy" Women's Christian Association Hospital, WCA Hospital (2009)
  • "Adjusting radiation therapy to improve outcomes: protectors, sensitizers, and/or mega-doses?" Research Division of the Department of Radiation Oncology, University of Pennsylvania, School of Medicine, Invited Speaker Seminar (2009)
  • "Following prostate cancer, increasing age and treatment modality (irradiation, surgery, surgery and adjuvant radiation) are highly significant predictors of developing bladder cancer, a SEER analysis" ASTRO Annual Meeting, ASTRO (2008)
  • "Hemoglobin, Treatment Time, and Local Failure Following Definitive Concurrent Chemo-IMRT for H&N Cancer" Therapists and Dosimetrists Conf., Roswell Park Cancer Institute, Radiation Medicine (2008)
  • "Dynamic contrast enhanced, MRI-guided trans-rectal biopsies in a closed 3 Tesla Scanner: Patient selection determines prostate cancer yield" ASCO Prostate Cancer Symposium, ASCO (2007)
  • "Concurrent 95 Gray IMRT Boost of Biopsy Proven, MRI Defined Dominant Intra-prostatic Lesions: Early Results of a Phase I NCI Study" ASTRO, ASTRO (2007)
  • "Imaging Individualization of Therapy & Rational Clinical Trial Design" Grand Rounds of the Eli Lilly Corporation, Eli Lilly Corporation (2007)
  • "Recent NCI Trials in Prostate Cancer: Radioproectors, MR Imaging, and Dose Escalation" , University of Nebraska (2007)
  • "Current and Future Prostate Imaging: Opportunities for Research & Rational Clinical Trial Designs" Center for Prostate Disease Research, Center for Prostate Disease Research (2006)
  • "Integration of MR Imaging into Radiation Oncology" , Washington University (2006)
  • "Optimization of Imaging for Target Volume Specification and Assessment" ASTRO Annual Mtg., ASTRO, Invited panelist (2006)
  • "Imaging, Individualization of Therapy & Rational Clinical Trial Design" , University of Arkansas for Medical Sciences (2006)
  • "Current Standards, Future Directions, and current NCI Clinical Research In Radiation Therapy for Prostate Cancer" NCI Symposium for Practicing Physicians: Focus on Prostate Cancer, National Cancer Institute (2006)
  • "Definition of Target Volumes, Imaging, & Opportunities For Clinical Research" Fourth Annual NCI-RRP Young Investigators Workshop, National Cancer Institute (2005)
  • "Concurrent Chemoradiation & Salvage of Isolated Para-aortic Lymph Node Recurrences" ASTRO Annual Mtg., ASTRO (2004)
  • "Review of Latest Developments in GI Cancers" ASTRO 2003 Review Course, Washington University, Eric P. Newman Center (2003)
  • "IMRT, PET, and Cervical Carcinoma" , National Cancer Institute, Department of Radiation Oncology (2003)
  • "Novel Imaging Methods for Assessment of Organ Motion and Target Delineation" , University of Florida, Department of Radiation Oncology (2003)
  • "Irradiation Dose, Lymph Node Size, and Tumor Control in Carcinoma of the Cervix" ASTRO Annual Mtg.- Poster Discussion, ASTRO (2003)
  • "Imaging Tumor Hypoxia In Vivo. Section WN BB4: Physiological Effects of Hyperthermia on Tumors and Normal Tissues" First International Congress on Stress Responses in Biology and Medicine (2003)
  • "Monitoring the Effect of 41 degree C Hyperthermia on Tumor Hypoxia by Cu-ATSM PET Scanning. Section WN BB2: Molecular Changes to Improve Clinical Responses" First International Congress on Stress Responses in Biology and Medicine (2003)
  • "FDG-PET Lymph Node Staging: Implications for the Treatment of Cervical Carcinoma." , University of Maryland, Department of Radiation Oncology (2003)
  • "FDG-PET Lymph Node Staging and Survival of Patients with FIGO Stage IIIB Cervical Carcinoma" ASTRO Annual Mtg., ASTRO (2002)
  • "Analysis of Clinical and Dosimetric Predictors of Radiation-Induced Esophageal Toxicity in Patients with Non Small Cell Lung Cancer Treated With Three Dimensional Conformal Radiation Therapy" ASTRO Annual Mtg., ASTRO (2001)
  • "Outcome of Patients with Rectal Adenocarcinoma and Localized Pelvic Non Nodal Metastatic Foci" 85th Scientific Assembly of the Radiological Society of North America Mtg., Radiological Society of North America (1999)
See all (33 more)

Service Activities:

  • NIH Review grants from Program Announcement PAR10-169; National Institutes of Health (NIH) ZRG1 SBIB-X(57)R Special Emphasis Panel on Academic-Industrial Partnerships for Translation of in vivo Imaging Systems for Cancer Investigations; Panel Member (2012–present)
  • Editorial Board Member; Editorial Board Member for World Journal of Clinical Oncology; Board Member (2010–present)
  • Manuscript Referee; Manuscript Referee for International Journal of Urology; Reviewer (2010–present)
  • Manuscript Referee; Manuscript Referee for Clinical Lung Cancer; Reviewer (2009–present)
  • Manuscript Referee; Manuscript Referee for American Family Physician; Reviewer (2009–present)
  • Manuscript Referee; Manuscript Referee for Journal of Urology; Reviewer (2009–present)
  • Radiation Therapy Oncology Group (RTOG) Membership Committee; Radiation Therapy Oncology Group (RTOG) Membership Committee; Member (2009–present)
  • Radiation Therapy Oncology Group (RTOG) Lung Cancer Steering Committee; Radiation Therapy Oncology Group (RTOG) Lung Cancer Steering Committee; Member (2008–2010)
  • Manuscript Referee; Manuscript Referee for Cancer Research; Reviewer (2008–present)
  • Radiation Therapy Oncology Group (RTOG) Full Member Prinicipal Investigator Committee; Radiation Therapy Oncology Group (RTOG) Full Member Prinicipal Investigator Committee; Member (2008–present)
  • ASTRO Gynecologic Abstract Reviewer; American Society of Therapeutic Radiation Oncology (ASTRO) Gynecologic Abstract Reviewer; Reviewer (2007–2009)
  • Manuscript Referee; Manuscript Referee for Radiation Oncology; Reviewer (2007–present)
  • Manuscript Referee; Manuscript Referee for Breast Cancer Research; Reviewer (2006–present)
  • NCI Panel on Advanced Technologies in Radiation Therapy; NCI Panel on Advanced Technologies in Radiation Therapy; Panel Member (2006–present)
  • Manuscript Referee; Manuscript Referee for International Journal of Radiation Oncology Biology Physics; Reviewer (2005–present)
  • Manuscript Referee; Manuscript Referee for Cancer; Reviewer (2005–present)
  • Manuscript Referee; Manuscript Referee for Clinical Cancer Research; Reviewer (2005–present)
  • Manuscript Referee; Manuscript Referee for American Journal of Clinical Oncology; Reviewer (2005–present)
  • Associate Guest Editor; Associate Guest Editor for Medical Physics; Editor (2004–present)
  • Manuscript Referee; Manuscript Referee for International Journal of Gynecological Cancer; Reviewer (2003–present)
  • AAPM Education of Physicians Subcommittee; AAPM Education of Physicians Subcommittee; Member (2002–2004)
  • ASTRO Refresher Course Committee; ASTRO Refresher Course Committee; Member (2002–2004)
  • ASTRO Education Committee; ASTRO Education Committee; Member (2002–2003)

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Contact Information

Roswell Park Cancer Institute
Dept. of Radiation Medicine
Elm and Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-3218
Fax: (716) 845-8254
as277@buffalo.edu

Looking for a doctor? This faculty member is affiliated with UBMD, the group comprised of practicing physicians who are also professors in the UB Jacobs School of Medicine and Biomedical Sciences.

View this faculty on UBMD