Ciprian N. Ionita PhD

Ciprian Ionita

Ciprian N. Ionita
PhD

Assistant Professor

Department of Biomedical Engineering

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Artificial Intelligence; Biomedical Imaging; Cardiovascular Disease; Diagnostic Radiology; Image Processing and Analysis; Imaging Informatics; Neurosurgery; Radiological Physics; Vascular and Interventional Radiology; Vision science

Contact Information
8052 Clinical Translational Research Center
875 Ellicott Street
N/A
Buffalo, New York 14203
Phone: 716-400-4283
cnionita@buffalo.edu



Professional Summary:

Ciprian N. Ionita, PhD, is Associate Professor in the Department of Biomedical Engineering at the University at Buffalo, with adjunct appointments in Radiology and Neurosurgery. He directs the Endovascular Device and Imaging Lab at the Canon Stroke and Vascular Research Center. His research focuses on quantitative imaging and image-guided treatment of neurovascular disease, with particular emphasis on angiographic analysis, computed tomography, patient-specific vascular models, and AI-based decision support for endovascular procedures.
His group develops methods to improve intraoperative assessment of intracranial aneurysm treatment, stroke severity, and cerebrovascular hemodynamics. This work integrates medical imaging, computational modeling, additive manufacturing, and device evaluation to build and validate quantitative tools that can be used in the angiography suite. The lab has also developed patient-specific neurovascular and cardiovascular phantoms for software validation, procedural simulation, and testing of endovascular devices.
A major current focus is translation of quantitative angiography and machine learning into clinically relevant tools for real-time procedural guidance. This includes NSF-supported work connected to QAS.AI on AI-enhanced angiographic systems for intracranial aneurysm treatment planning and outcome prediction. Dr. Ionita has also contributed to national efforts in standardization of medical 3D printing through the RSNA 3D Printing Special Interest Group.

Education and Training:

  • PhD, Medical Physics, SUNY at Buffalo (2005)
  • BS, Applied Nuclear Physics, University of Bucharest

Employment:

  • Faculty, Biomedical Engineering, SUNY at Buffalo School of Engineering and Applied Sciences (2014-present)

Awards and Honors:

  • Betas 2025 award for AI and emerging technology innovation excellence award (2025)
  • Poster Cum Laude Award E (2025)
  • AI Fund for Surgery for Data-Driven Healthcare (2025)
  • Investigator award (2024)
  • Poster Cum Laude (2022)
  • Poster Cum Laude (2019)
  • Honorable Mention (2018)
  • Cum Laude (2015)
  • Honorable Mention (2009)
  • Educational Poster Award (2002)

Research Expertise:

  • 3D Printing
  • Computed Tomography and Micro-Computed Tomography
  • Endovascular Devices
  • Vascular Disease Diagnosis and Modeling

Grants and Sponsored Research:

  • October 2022–September 2024
    Hemodynamically induced molecules regulating the initiation of intracranial aneurysms
    Role: Co-Investigator
    $438,835
  • April 2020–March 2024
    High Speed Angiography at 1000 frames per second
    NIH
    Role: Co-Investigator
    $3,000,000
  • August 2021–July 2023
    Data-driven models to predict delayed cerebral ischemia after subarachnoid hemorrhage
    NIH
    Role: Co-Principal Investigator
    $448,500
  • July 2021–June 2023
    STTR: An AI-Enhanced Angiographic System to Guide Endovascular Treatment of Intracranial Aneurysms
    NSF
    Role: Co-Investigator
    $275,000
  • January 2021–September 2022
    Artificial Intelligence Quantitative Angiographic System to Guide Endovascular Procedures
    NSF
    Role: Principal Investigator
    $50,000
  • June 2020–May 2021
    Quantitative angiography for real time neuro-interventional guidance
    NYS
    Role: Principal Investigator
    $100,000
  • January 2017–January 2019
    Validation of a CT based FFR software using the 640 Slices Aquilion Scanner
    Jacobs Institute
    Role: Co-Investigator
    $81,115
  • August 2016–August 2017
    In-Vivo feasibility testing of an Asymmetric Flow Diverter based on Solitaire AB platform for treatment of intracranial aneurysms
    Medtronic-Jacobe Institute industry collaboration
    Role: Principal Investigator
    $93,501
  • August 2012–July 2016
    Microangiographic guidance of flow modifying stents - renewal
    NIH
    Role: Co-Investigator
    $2,526,475

Patents:

  • METHODS AND SYSTEMS FOR ASSESSING A VASCULATURE Methods and systems are provided for assessing a vasculature of an individual. In an embodiment of a method, one or more angiographic parametric imaging (API) maps of the vasculature are obtained, wherein each API map of the one or more API maps encodes a hemodynamic parameter. A state of the vasculature is determined using a machine-learning classifier applied to the one or more API maps. (2021)
  • X-ray diagnostic apparatus and medical image processing method An X ray diagnostic apparatus includes an X ray tube generating X rays, a first detector detecting the X rays, at least one second detector arranged in front of a first detection surface of the first detector and including a second detection surface narrower than the first detection surface and indicator points provided on a rear surface of the second detection surface, a projection data generation unit generating first projection data based on an output from the first detector, and a positional shift detection unit detecting a positional shift of the second detector relative to the first detector in accordance with an imaging direction by using the first projection data and a predetermined positional relationship between the points and detection elements in the second detector. (2017)

Journal Articles:

See all (126 more)

Abstracts:

See all (57 more)

Professional Memberships:

  • American Association of Phycists in Medicine (2003–present)
  • SPIE (2003–present)
  • Radiology Society of North America; Member

Service Activities:

  • Past President: Upstate New York Association of Physicist in Medicine 01/2013- 12/2013 President Elect: Upstate New York Association of Physicist in Medicine (UNYAPM) a chapter of the American Association of Physicist in Medicine; Past President (2015)
  • NIH; Neuroscience and Ophthalmic Imaging Technologies;; Grant Reviewer (2014)
  • President: Upstate New York Association of Physicist in Medicine President: Upstate New York Association of Physicist in Medicine; President (2013–2014)
  • Reviewer: American Association of Physicists in Medicine meetings Reviewer: Medical Physics,AAPM meetings , Physics in Medicine and Biology (PMB), Biomechanics and Modeling in Mechanobiology, American Journal of Neuroradiology (AJNR).; Peer Reviewer (2010–present)
  • Treasurer: Upstate New York Association of Physicist in Medicine 01/2009-12/2011 Treasurer: Upstate New York Association of Physicist in Medicine (UNYAPM) a chapter of the American Association of Physicist in Medicine.; Treasurer (2009–2011)
  • Reviewer: Medical Physics; Peer Reviewer (2004–present)
  • Reviewer: Physics in Medicine and Biology Reviewer: Medical Physics,AAPM meetings , Physics in Medicine and Biology (PMB), Biomechanics and Modeling in Mechanobiology, American Journal of Neuroradiology (AJNR).; Peer Reviewer (2004–present)

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Contact Information

8052 Clinical Translational Research Center
875 Ellicott Street
N/A
Buffalo, New York 14203
Phone: 716-400-4283
cnionita@buffalo.edu