Norma J. Nowak PhD
Norma J. Nowak
PhD
Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Bioinformatics; Genomics and proteomics; Molecular genetics
Research Centers:
- Center of Excellence in Bioinformatics and Life Sciences
UB 2020 Strategic Strengths:
- Molecular Recognition in Biological Systems and Bioinformatics
Grants and Sponsored Research:
- April 2006–March 2010
Biomarkers for the Progression of Head and Neck Squamous Cell Carcinoma
NCI
Role: Principal Investigator
$1,270,914 - December 2005–December 2009
Genomic and Bioinformatic Approaches to Understanding Animal Development
NASA
Role: Co-Investigator
$330,667 - November 2005–October 2009
NYS Center of Excellence in Bioinformatics & Life Sciences: Structural Biology
NASA
Role: Co-Investigator
$3,968,000 - September 2005–September 2009
Systems Biology and Bioinformatics in Medical Applications
Army
Role: Co-Investigator
$4,872,680 - July 2004–June 2009
Center of Excellence in Bioinformatics
DOE
Role: Co-Investigator
$2,655,000 - March 2007–February 2009
Empirical Assessment of Analysis Methods for DNA Microarrays
NIH/NLM
Role: Co-Investigator
$79,250 - July 2003–June 2008
Restriction landmark genomic analysis of cancer
NIH/NCI
Role: Co-Investigator
$250,000 - January 2004–May 2007
Buffalo Center of Excellence in Bioinformatics: Astrobiology
NASA
Role: Co-Investigator
$4,471,000 - December 2005–December 2006
Genomic and Bioinformatic approaches to understanding animal development
NASA
Role: Co-Investigator
$992,000 - May 2003–April 2006
Pilot and Feasibility Program Related to the Kidney Array Based CGH for Genome Wide Analysis of Wilm's Tumor
NCI/NIH
Role: Principal Investigator
$200,000 - April 2005–March 2006
Determination of copy number changes using BAC array-CGH and RLS Technology
Invitrogen, Inc.
Role: Principal Investigator
$120,000 - April 2003–March 2006
Pharmacogenetics: Breast Cancer Treatment and Prognosis
NCI
Role: Co-Investigator
$225,000 - February 1998–March 2006
Genomic Instability in Human Colorectal Cancer
NCI
Role: Co-Investigator
$166,250 - March 2005–February 2006
Biomarkers for the Progression of Head and Neck Squamous Cell Carcinoma
The Charlotte Geyer Foundation
Role: Principal Investigator
$83,000 - October 2000–February 2004
High Throughput Analysis of Gene Expression Patterns in the Nervous System
Rochefeller University - Subcontract NINDS
Role: Co-Investigator
$1,854,259 - September 1998–September 2003
A Resource of arrayed BAC Clones for FISH Mapping of the Human Genome
NCI
Role: Principal Investigator
$1,084,188 - April 2002–April 2003
Affymetrix 437 Arrayer
NCI - National Center for Research Resources
Role: Principal Investigator
$125,000 - April 2000–March 2001
DNA Microarray Infrastructure for Model Organism Research
Roswell Park Alliance Foundation
Role: Principal Investigator
$98,000 - Traffic Air Pollution, Genetic Variation and Autism Spectrum Disorder
RENEW Institute and the Office of the Vice President for Research and Economic Development
Role: Co-Investigator
$32,990
Journal Articles:
- Buck MJ, Raaijmakers LM, Ramakrishnan S, Wang D, Valiyaparambil S, Liu S, Nowak NJ, Pili R. Alterations in chromatin accessibility and DNA methylation in clear cell renal cell carcinoma. Oncogene. 2014; 33(41).
- Chitta KS, Paulus A, Ailawadhi S, Foster BA, Moser MT, Starostik P, Masood A, Sher T, Miller KC, Iancu DM, Conroy J, Nowak NJ, Sait SN, Personett DA, Coleman M, Furman RR, Martin P, Ansell SM, Lee K, Chanan-Khan AA. Development and characterization of a novel human Waldenström macroglobulinemia cell line: RPCI-WM1, Roswell Park Cancer Institute - Waldenström Macroglobulinemia 1. Leuk Lymphoma. 2013; 54(2).
- Liao S, Desouki MM, Gaile DP, Shepherd L, Nowak NJ, Conroy J, Barry WT, Geradts J. Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast. Genes Chromosomes Cancer. 2012; 51(12).
- Liu C, Morishima M, Yu T, Matsui S, Zhang L, Fu D, Pao A, Costa AC, Gardiner KJ, Cowell JK, Nowak NJ, Nowak NJ, Parmacek MS, Liang P, Baldini A, Yu YE. Genetic analysis of Down syndrome-associated heart defects in mice. Hum Genet. 2011; 130(5).
- Liu C, Morishima M, Yu T, Matsui S, Zhang L, Fu D, Pao A, Costa AC, Gardiner KJ, Cowell JK, Nowak NJ, Nowak NJ, Parmacek MS, Liang P, Baldini A, Yu YE. Genetic analysis of Down syndrome-associated heart defects in mice. Hum Genet. 2011; 130(5).
- Yao S, Sucheston LE, Smiley SL, Davis W, Conroy JM, Nowak NJ, Ambrosone CB, McCarthy PL, Hahn T. Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation. PLoS One. 2011; 6(10).
- Slovak ML, Bedell V, Hsu YH, Estrine DB, Nowak NJ, Delioukina ML, Weiss LM, Smith DD, Forman SJ. Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma. Clin Cancer Res. 2011; 17(10).
- Desouki MM, Liao S, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J. The genomic relationship between primary breast carcinomas and their nodal metastases. Cancer Invest. 2011; 29(4).
- Desouki MM, Liao S, Huang H, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J. Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach. J Cancer Res Clin Oncol. 2011; 137(5).
- Yu T, Li Z, Jia Z, Clapcote SJ, Liu C, Li S, Asrar S, Pao A, Chen R, Fan N, Carattini-Rivera S, Bechard AR, Spring S, Henkelman RM, Stoica G, Matsui S, Nowak NJ, Roder JC, Chen C, Bradley A, Yu YE. A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Hum Mol Genet. 2010; 19(14).
- Pavone P, Ruggieri M, Lombardo I, Sudi J, Biancheri R, Castellano-Chiodo D, Rossi A, Incorpora G, Nowak NJ, Christian SL, Pavone L, Dobyns WB. Microcephaly, sensorineural deafness and Currarino triad with duplication-deletion of distal 7q. Eur J Pediatr. 2010; 169(4).
- Kumar RA, Sudi J, Babatz TD, Brune CW, Oswald D, Yen M, Nowak NJ, Cook EH, Christian SL, Dobyns WB. A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism. J Med Genet. 2010; 47(2).
- Nemajerova A, Palacios G, Nowak NJ, Matsui S, Petrenko O. Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesis. PLoS One. 2009; 4(11).
- Williams SR, Girirajan S, Tegay D, Nowak NJ, Hatchwell E, Elsea SH. Array comparative genomic hybridization of 52 subjects with a Smith-Magenis-like phenotype: identification of dosage-sensitive loci also associated with schizophrenia, autism, and developmental delay. J Med Genet. 2009.
- Horst B, Gruvberger-Saal SK, Hopkins BD, Bordone L, Yang Y, Chernoff KA, Uzoma I, Schwipper V, Liebau J, Nowak NJ, Brunner G, Owens D, Rimm DL, Parsons R, Celebi JT. Gab2-mediated signaling promotes melanoma metastasis. Am J Pathol. 2009; 174(4).
- Bruce HA, Sachs N, Rudnicki DD, Lin SG, Willour VL, Cowell JK, Conroy J, McQuaid DE, Rossi M, Gaile DP, Nowak NJ, Holmes SE, Sklar P, Ross CA, Delisi LE, Margolis RL. Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations. Psychiatr Genet. 2009; 19(2).
- Xiang B, Li A, Valentin D, Nowak NJ, Zhao H, Li P. Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am J Med Genet A. 2008; 146A(15).
- Yi Y, Nowak NJ, Pacchia AL, Morrison C. Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarrays. Genes Chromosomes Cancer. 2008; 47(8).
- Christian SL, Brune CW, Sudi J, Kumar RA, Liu S, Karamohamed S, Badner JA, Matsui S, Conroy J, McQuaid D, Gergel J, Hatchwell E, Gilliam TC, Gershon ES, Nowak NJ, Dobyns WB, Cook EH. Novel submicroscopic chromosomal abnormalities detected in autism spectrum disorder. Biol Psychiatry. 2008; 63(12).
- Kumar RA, KaraMohamed S, Sudi J, Conrad DF, Brune C, Badner JA, Gilliam TC, Nowak NJ, Cook EH, Dobyns WB, Christian SL. Recurrent 16p11.2 microdeletions in autism. Hum Mol Genet. 2008; 17(4).
- Gaile DP, Schifano ED, Miecznikowski JC, Java JJ, Conroy JM, Nowak NJ. Estimating the arm-wise false discovery rate in array comparative genomic hybridization experiments. Stat Appl Genet Mol Biol. 2007; 6.
- Auer H, Newsom DL, Nowak NJ, McHugh KM, Singh S, Yu CY, Yang Y, Wenger GD, Gastier-Foster JM, Kornacker K. Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarrays. BMC Genomics. 2007; 8.
- Chung I, Karpf AR, Muindi JR, Conroy JM, Nowak NJ, Johnson CS, Trump DL. Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. J Biol Chem. 2007; 282(12).
- Bartos JD, Gaile DP, McQuaid DE, Conroy JM, Darbary H, Nowak NJ, Block A, Petrelli NJ, Mittelman A, Stoler DL, Anderson GR. aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including BCR and ABL. Mutat Res. 2007; 615(1-2).
- Alrawi SJ, Carroll RE, Hill HC, Gibbs JF, Tan D, Brenner BM, Nowak NJ, Swede H, Stoler DL, Anderson GR. Genomic instability of human aberrant crypt foci measured by inter-(simple sequence repeat) PCR and array-CGH. Mutat Res. 2006; 601(1-2).
- Smith LT, Mayerson J, Nowak NJ, Suster D, Mohammed N, Long S, Auer H, Jones S, McKeegan C, Young G, Bos G, Plass C, Morrison C. 20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcome. Genes Chromosomes Cancer. 2006; 45(10).
- Swede H, Bartos JD, Chen N, Shaukat A, Dutt SS, McQuaid DA, Natarajan N, Rodriguez-Bigas MA, Nowak NJ, Wiseman SM, Alrawi S, Brenner BM, Petrelli NJ, Cummings KM, Stoler DL, Anderson GR. Genomic profiles of colorectal cancers differ based on patient smoking status. Cancer Genet Cytogenet. 2006; 168(2).
- Rossi MR, Conroy J, McQuaid D, Nowak NJ, Rutka JT, Cowell JK. Array CGH analysis of pediatric medulloblastomas. Genes Chromosomes Cancer. 2006; 45(3).
- Shankar G, Rossi MR, McQuaid DE, Conroy JM, Gaile DG, Cowell JK, Nowak NJ, Liang P. aCGHViewer: A Generic Visualization Tool For aCGH data. Cancer Inform. 2006; 2.
- Cowell JK, LaDuca J, Rossi MR, Burkhardt T, Nowak NJ, Matsui S. Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line. Cancer Genet Cytogenet. 2005; 163(1).
- Rossi MR, Gaile D, Laduca J, Matsui S, Conroy J, McQuaid D, Chervinsky D, Eddy R, Chen HS, Barnett GH, Nowak NJ, Cowell JK. Identification of consistent novel submegabase deletions in low-grade oligodendrogliomas using array-based comparative genomic hybridization. Genes Chromosomes Cancer. 2005; 44(1).
- Nowak NJ, Gaile D, Conroy JM, McQuaid D, Cowell J, Carter R, Goggins MG, Hruban RH, Maitra A. Genome-wide aberrations in pancreatic adenocarcinoma. Cancer Genet Cytogenet. 2005; 161(1).
- Nowak NJ, Snijders AM, Conroy JM, Albertson DG. The BAC resource: tools for array CGH and FISH. Curr Protoc Hum Genet. 2005; Chapt.
- Minderman H, Conroy JM, O'Loughlin KL, McQuaid D, Quinn P, Li S, Pendyala L, Nowak NJ, Baer MR. In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells. Mol Cancer Ther. 2005; 4(6).
- Kimura MT, Mori T, Conroy J, Nowak NJ, Satomi S, Tamai K, Nagase H. Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk. Cancer Res. 2005; 65(9).
- Snijders AM, Nowak NJ, Huey B, Fridlyand J, Law S, Conroy J, Tokuyasu T, Demir K, Chiu R, Mao JH, Jain AN, Jones SJ, Balmain A, Pinkel D, Albertson DG. Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res. 2005; 15(2).
- Cowell JK, Matsui S, Wang YD, LaDuca J, Conroy J, McQuaid D, Nowak NJ. Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme. Cancer Genet Cytogenet. 2004; 151(1).
- Cowell JK, Wang YD, Head K, Conroy J, McQuaid D, Nowak NJ. Identification and characterisation of constitutional chromosome abnormalities using arrays of bacterial artificial chromosomes. Br J Cancer. 2004; 90(4).
- Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 2003; 425(6961).
- Hackett CS, Hodgson JG, Law ME, Fridlyand J, Osoegawa K, de Jong PJ, Nowak NJ, Pinkel D, Albertson DG, Jain A, Jenkins R, Gray JW, Weiss WA. Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Res. 2003; 63(17).
- Bruce CK, Howard P, Nowak NJ, Hoban PR. Molecular analysis of region t(5;6)(q21;q21) in Wilms tumor. Cancer Genet Cytogenet. 2003; 141(2).
- Cowell JK, Nowak NJ. High-resolution analysis of genetic events in cancer cells using bacterial artificial chromosome arrays and comparative genome hybridization. Adv Cancer Res. 2003; 90.
- Sait SN, Qadir MU, Conroy JM, Matsui S, Nowak NJ, Baer MR. Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndrome: identification of new amplification regions by fluorescence in situ hybridization and spectral karyotyping. Genes Chromosomes Cancer. 2002; 34(1).
- Anderson GR, Brenner BM, Swede H, Chen N, Henry WM, Conroy JM, Karpenko MJ, Issa JP, Bartos JD, Brunelle JK, Jahreis GP, Kahlenberg MS, Basik M, Sait S, Rodriguez-Bigas MA, Nowak NJ, Petrelli NJ, Shows TB, Stoler DL. Intrachromosomal genomic instability in human sporadic colorectal cancer measured by genome-wide allelotyping and inter-(simple sequence repeat) PCR. Cancer Res. 2001; 61(22).
- Zhang J, Qin S, Sait SN, Haley LL, Henry WM, Higgins MJ, Nowak NJ, Shows TB, Gerhard DS. The pericentromeric region of human chromosome 11: evidence for a chromosome-specific duplication. Cytogenet Cell Genet. 2001; 94(3-4).
- van Schie RC, Marras SA, Conroy JM, Nowak NJ, Catanese JJ, de Jong PJ. Semiautomated clone verification by real-time PCR using molecular beacons. Biotechniques. 2000; 29(6).
- Zaroff JG, Rordorf GA, Titus JS, Newell JB, Nowak NJ, Torchiana DF, Aretz HT, Picard MH, Macdonald RL. Regional myocardial perfusion after experimental subarachnoid hemorrhage. Stroke. 2000; 31(5).
- Zhao XF, Nowak NJ, Shows TB, Aplan PD. MAGOH interacts with a novel RNA-binding protein. Genomics. 2000; 63(1).
- Caldwell GM, Kakuk LE, Griesinger IB, Simpson SA, Nowak NJ, Small KW, Maumenee IH, Rosenfeld PJ, Sieving PA, Shows TB, Ayyagari R. Bestrophin gene mutations in patients with Best vitelliform macular dystrophy. Genomics. 1999; 58(1).
- Weber TK, Conroy J, Keitz B, Rodriguez-Bigas M, Petrelli NJ, Stoler DL, Anderson GR, Shows TB, Nowak NJ. Genome-wide allelotyping indicates increased loss of heterozygosity on 9p and 14q in early age of onset colorectal cancer. Cytogenet Cell Genet. 1999; 86(2).
- O'Keefe DS, Su SL, Bacich DJ, Horiguchi Y, Luo Y, Powell CT, Zandvliet D, Russell PJ, Molloy PL, Nowak NJ, Shows TB, Mullins C, Vonder Haar RA, Fair WR, Heston WD. Mapping, genomic organization and promoter analysis of the human prostate-specific membrane antigen gene. Biochim Biophys Acta. 1998; 1443(1-2).
- Varon R, Vissinga C, Platzer M, Cerosaletti KM, Chrzanowska KH, Saar K, Beckmann G, Seemanová E, Cooper PR, Nowak NJ, Stumm M, Weemaes CM, Gatti RA, Wilson RK, Digweed M, Rosenthal A, Sperling K, Concannon P, Reis A. Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell. 1998; 93(3).
- Cooper PR, Nowak NJ, Higgins MJ, Church DM, Shows TB. Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes. Genomics. 1998; 49(3).
- Cooper PR, Smilinich NJ, Day CD, Nowak NJ, Reid LH, Pearsall RS, Reece M, Prawitt D, Landers J, Housman DE, Winterpacht A, Zabel BU, Pelletier J, Weissman BE, Shows TB, Higgins MJ. Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain. Genomics. 1998; 49(1).
- Zhao XF, Colaizzo-Anas T, Nowak NJ, Shows TB, Elliott RW, Aplan PD. The mammalian homologue of mago nashi encodes a serum-inducible protein. Genomics. 1998; 47(2).
- Higgins MJ, Day CD, Smilinich NJ, Ni L, Cooper PR, Nowak NJ, Davies C, de Jong PJ, Hejtmancik F, Evans GA, Smith RJ, Shows TB. Contig maps and genomic sequencing identify candidate genes in the usher 1C locus. Genome Res. 1998; 8(1).
- Stöhr H, Marquardt A, Rivera A, Cooper PR, Nowak NJ, Shows TB, Gerhard DS, Weber BH. A gene map of the Best's vitelliform macular dystrophy region in chromosome 11q12-q13.1. Genome Res. 1998; 8(1).
- Crider-Miller SJ, Reid LH, Higgins MJ, Nowak NJ, Shows TB, Futreal PA, Weissman BE. Novel transcribed sequences within the BWS/WT2 region in 11p15.5: tissue-specific expression correlates with cancer type. Genomics. 1997; 46(3).
- Watson B, Nowak NJ, Myracle AD, Shows TB, Warnock DG. The human angiotensinase C gene (HUMPCP) maps to 11q14 within 700 kb of D11S901: a candidate gene for essential hypertension. Genomics. 1997; 44(3).
- Reid LH, Davies C, Cooper PR, Crider-Miller SJ, Sait SN, Nowak NJ, Evans G, Stanbridge EJ, deJong P, Shows TB, Weissman BE, Higgins MJ. A 1-Mb physical map and PAC contig of the imprinted domain in 11p15.5 that contains TAPA1 and the BWSCR1/WT2 region. Genomics. 1997; 43(3).
- Guru SC, Olufemi SE, Manickam P, Cummings C, Gieser LM, Pike BL, Bittner ML, Jiang Y, Chinault AC, Nowak NJ, Brzozowska A, Crabtree JS, Wang Y, Roe BA, Weisemann JM, Boguski MS, Agarwal SK, Burns AL, Spiegel AM, Marx SJ, Flejter WL, de Jong PJ, Collins FS, Chandrasekharappa SC. A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13. Genomics. 1997; 42(3).
- Cooper PR, Nowak NJ, Higgins MJ, Simpson SA, Marquardt A, Stoehr H, Weber BH, Gerhard DS, de Jong PJ, Shows TB. A sequence-ready high-resolution physical map of the best macular dystrophy gene region in 11q12-q13. Genomics. 1997; 41(2).
- Courseaux A, Szepetowski P, Fernandes M, Serizet C, Kawaguchi Y, Grosgeorge J, Perucca-Lostanlen D, Shows TB, Todd JA, Nowak NJ, Gaudray P. Framework YAC contig anchored into a 3.2-Mb high-resolution physical map in proximal 11q13. Genomics. 1997; 40(1).
- Merscher S, Bekri S, de Leeuw B, Pedeutour F, Grosgeorge J, Shows TB, Müllenbach R, Le Paslier D, Nowak NJ, Gaudray P. A 5.5-Mb high-resolution integrated map of distal 11q13. Genomics. 1997; 39(3).
- Bowen MA, Whitney GS, Neubauer M, Starling GC, Palmer D, Zhang J, Nowak NJ, Shows TB, Aruffo A. Structure and chromosomal location of the human CD6 gene: detection of five human CD6 isoforms. J Immunol. 1997; 158(3).
- Wuyts W, Van Hul W, Wauters J, Nemtsova M, Reyniers E, Van Hul EV, De Boulle K, de Vries BB, Hendrickx J, Herrygers I, Bossuyt P, Balemans W, Fransen E, Vits L, Coucke P, Nowak NJ, Shows TB, Mallet L, van den Ouweland AM, McGaughran J, Halley DJ, Willems PJ. Positional cloning of a gene involved in hereditary multiple exostoses. Hum Mol Genet. 1996; 5(10).
- Qin S, Nowak NJ, Zhang J, Sait SN, Mayers PG, Higgins MJ, Cheng Y, Li L, Munroe DJ, Gerhard DS, Weber BH, Bric E, Housman DE, Evans GA, Shows TB. A high-resolution physical map of human chromosome 11. Proc Natl Acad Sci U S A. 1996; 93(7).
- Perlin MW, Duggan DJ, Davis K, Farr JE, Findler RB, Higgins MJ, Nowak NJ, Evans GA, Qin S, Zhang J. Rapid construction of integrated maps using inner product mapping: YAC coverage of human chromosome 11. Genomics. 1995; 28(2).
- Polakiewicz RD, Munroe DJ, Sait SN, Tycowski KT, Nowak NJ, Shows TB, Housman DE, Page DC. Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3-q13.5. Genomics. 1995; 25(2).
- Nowak NJ, Shows TB. Genetics of chromosome 11: loci for pediatric and adult malignancies, developmental disorders, and other diseases. Cancer Invest. 1995; 13(6).
- Rotman G, Savitsky K, Ziv Y, Cole CG, Higgins MJ, Bar-Am I, Dunham I, Bar-Shira A, Vanagaite L, Qin S, Zhang J, Nowak NJ, Chandrasekharappa SC, Lehrach H, Avivi L, Shows TB, Collins FS, Bentley DR, Shiloh Y. A YAC contig spanning the ataxia-telangiectasia locus (groups A and C) at 11q22-q23. Genomics. 1994; 24(2).
- Sait SN, Nowak NJ, Singh-Kahlon P, Weksberg R, Squire J, Shows TB, Higgins MJ. Localization of Beckwith-Wiedemann and rhabdoid tumor chromosome rearrangements to a defined interval in chromosome band 11p15.5. Genes Chromosomes Cancer. 1994; 11(2).
- Sanford JP, Sait SN, Pan L, Nowak NJ, Gill HJ, Le Beau MM, Diaz MO, Zabel B, Shows TB. Characterization of two 11q23.3-11q24 deletions and mapping of associated anonymous DNA markers. Genes Chromosomes Cancer. 1993; 7(2).
- Qin S, Zhang J, Isaacs CM, Nagafuchi S, Jani Sait SN, Abel KJ, Higgins MJ, Nowak NJ, Shows TB. A chromosome 11 YAC library. Genomics. 1993; 16(3).
- Sanford J, Kim BW, Deaven LL, Jones C, Higgins MJ, Nowak NJ, Shows TB. A human chromosome 11 NotI end clone library. Genomics. 1993; 15(3).
- Nakai H, Byers MG, Nowak NJ, Shows TB. Assignment of beta-hexosaminidase A alpha-subunit to human chromosomal region 15q23----q24. Cytogenet Cell Genet. 1991; 56(3-4).
- Fan YS, Eddy RL, Byers MG, Haley LL, Henry WM, Nowak NJ, Shows TB. The human mineralocorticoid receptor gene (MLR) is located on chromosome 4 at q31.2. Cytogenet Cell Genet. 1989; 52(1-2).
- Davis LM, Byers MG, Fukushima Y, Qin SZ, Nowak NJ, Scoggin C, Shows TB. Four new DNA markers are assigned to the WAGR region of 11p13: isolation and regional assignment of 112 chromosome 11 anonymous DNA segments. Genomics. 1988; 3(3).
- Davis LM, Stallard R, Thomas GH, Couillin P, Junien C, Nowak NJ, Shows TB. Two anonymous DNA segments distinguish the Wilms' tumor and aniridia loci. Science. 1988; 241(4867).
- Tan MH, Nowak NJ, Loor R, Ochi H, Sandberg AA, Lopez C, Pickren JW, Berjian R, Douglass HO, Chu TM. Characterization of a new primary human pancreatic tumor line. Cancer Invest. 1986; 4(1).
- Shows TB, Davis LM, Qin S, Nowak NJ. The chromosome 11 gene map: genes for growth and development, Wilms' tumor deletions, and cancer chromosome breakpoints. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt.
- Loor R, Nowak NJ, Manzo ML, Douglass HO, Chu TM. Use of pancreas-specific antigen in immunodiagnosis of pancreatic cancer. Clin Lab Med. 1982; 2(3).
- Pavelic ZP, Slocum HK, Rustum YM, Creaven PJ, Nowak NJ, Karakousis C, Takita H, Mittelman A. Growth of cell colonies in soft agar from biopsies of different human solid tumors. Cancer Res. 1980; 40(11).
Evaluative Studies and Case Reports:
- Sait SN, Claydon MA, Conroy JM, Nowak NJ, Barcos M, Baer MR. Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia. Cancer Genet Cytogenet. 2007; 177(2).
- Girirajan S, Mendoza-Londono R, Vlangos CN, Dupuis L, Nowak NJ, Bunyan DJ, Hatchwell E, Elsea SH. Smith-Magenis syndrome and Moyamoya disease in a patient with del(17)(p11.2p13.1). Am J Med Genet A. 2007; 143A(9).
- Drazinic CM, Ercan-Sencicek AG, Gault LM, Hisama FM, Qumsiyeh MB, Nowak NJ, Cubells JF, State MW. Rapid array-based genomic characterization of a subtle structural abnormality: a patient with psychosis and der(18)t(5;18)(p14.1;p11.23). Am J Med Genet A. 2005; 134(3).
- Chervinsky DS, Sait SN, Nowak NJ, Shows TB, Aplan PD. Complex MLL rearrangement in a patient with T-cell acute lymphoblastic leukemia. Genes Chromosomes Cancer. 1995; 14(1).