The main focus of my research is to develop novel optical and ultrasonic imaging techniques to meet needs in cancer and neurological research. In my lab, students will have the opportunities to be trained in optical and ultrasonic engineering, be involved with preclinical and clinical imaging studies, and be collaborating with chemists, physicians and neurologists in Western New York and Ontario Canada.
Education and Training:
PhD, Mechanical Engineering, University of Toronto (2010)
BS, Applied Physics, University of Science and Technology of China (2004)
Associate Professor, Biomedical Engineering, University at Buffalo School of Engineering and Applied Sciences (2020-present)
Assistant Professor, University at Buffalo School of Engineering and Applied Sciences (2014–2020)
Post Doctoral Fellow, Biomedical Engineering, Washington University in St. Louis School of Engineering and Applied Sciences (2010–2014)
Grants and Sponsored Research:
May 2021–February 2025 Development of photoacoustic tomography for non-invasive, label-free imaging of tissue perfusion in chronic wounds NIH Role: Principal Investigator $1,640,000
May 2020–December 2023 Multiparametric photoacoustic and ultrasonic imaging of the breast in cranial-caudal view NIH Role: Principal Investigator $1,420,000
July 2017–January 2021 Breast cancer screening through the combination of light and ultrasound Susan G. Komen Foundation Role: Principal Investigator $450,000
September 2015–August 2017 Potentiometric photoacoustic imaging of brain activity enabled by near infrared to visible light converting nanoparticles NIH Role: Principal Investigator $447,197
February 2016–March 2017 Development of a Multisensory System for Continuous Monitoring of Blood Glucose Level University at Buffalo Innovative Micro-Programs Accelerating Collaboration in Themes (IMPACT) Role: Principal Investigator $35,000
September 2015–October 2016 Brain Network: Nanomaterials Enabled Functional Imaging The Research Foundation for SUNY Role: Co-Investigator $450,000
Liu B, C Li, G Chen, B Liu, X Deng, Y Wei, J Xia, B Xing, Pa Ma, and J Lin. (2016) Synthesis and Optimization of MoS2@ Fe3O4‐ICG/Pt (IV) Nanoflowers for MR/IR/PA Bioimaging and Combined PTT/PDT/Chemotherapy Triggered by 808 nm Laser. Advanced Science (Jul), 4: 4884-4894.
L. Lei, J. Xia, G. Li, A. Garcia-Uribe, Q. Sheng, M.A. Anastasio, and L.V. Wang. (2016) Label-free photoacoustic tomography of whole mouse brain structures ex vivo. Neurophotonics (Jul), 3(3): 1-8.
Wan H. Zhou Y. Ying L. Meng J. Song L. Xia J. . (2016) Enabling high-speed wide-field dynamic imaging in multifocal photoacoustic computed microscopy: a simulation study. Applied Optics (Apr), 55(14): 3724-3729.
Xia J, Mandelis, A. (2010) Direct-search deep level photothermal spectroscopy: An enhanced reliability method for overlapped semiconductor defect state characterization. Applied Physics Letters (Jun), 96(26).
Xia J, Mandelis, A. (2009) Radiative defect state identification in semi-insulating GaAs using photo-carrier Radiometry. Semiconductor Science and Technology (Dec).
Xia J, Mandelis, A. (2009) Broadening effects and ergodicity in deep level photothermal spectroscopy of defect states in semi-insulating GaAs: A combined temperature-, pulse-rate-, and time-domain study of defect state kinetics. Journal of Applied Physics (May), 105(10).
Xia J, Mandelis, A. (2008) Deep level photothermal spectroscopy: Physical principles and applications to semi-insulating GaAs band-gap multiple trap states. Journal of Applied Physics (Feb), 103: 43704.
Xia J, Mandelis, A. (2007) Noncontact deep level photo-thermal spectroscopy: Technique and application to semi-insulating GaAs Wafers. Applied physics letters (Feb), 90(6): 62119.