Robert S. Miletich MD PhD
Robert S. Miletich
MD PhD
Interim Chair and Professor
Department of Nuclear Medicine
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Neurodegenerative disorders; Neurology; Nuclear Medicine
Education and Training:
- Residency, Nuclear Medicine, NIH (1993)
- Fellowship, NINDS (NIH) (1986)
- Residency, Neurology, UCLA (1986)
- PhD, Neuropharmacology, University of Illinois Health Sciences Center (1985)
- MD, Nuclear Medicine, University of Illinois Health Sciences Center (1981)
- BS, General Science and Sociology, University of Iowa (1976)
Employment:
- Medical Director, Nuclear Medicine Technology Program, University at Buffalo (2010-present)
- Program Director, Nuclear Medicine Residency Program, University at Buffalo (2010-present)
- CME Program Director, Department of Nuclear Medicine, University at Buffalo (2008-present)
- Professor, Nuclear Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2006-present)
- Associate Professor, Nuclear Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2004–2006)
- Associate Professor, Department of Neurology, University at Buffalo School of Medicine and Biomedical Sciences (2004–2006)
Awards and Honors:
- Outstanding Accreditation Award, Nuclear Medicine Residency (2011)
- Collimator Award for teaching excellence (1998,2000,2008) (2008)
- Fellow of the American Association for the Advancement of Science (1991)
- Medical Scientist Scholarship (1985)
- Alpha Omega Alpha Honor Medical Society (1980)
- Phi Beta Kappa Honor Society (1975)
Research Expertise:
- Editorial Consultant: Archives of Neurology. Journal of Neuroimaging. Journal of Computed Assisted Tomography. Neuropharmacology. Pharmacopeial Forum
Grants and Sponsored Research:
- January 2013–December 2017
Advancing Schizophrenia Treatment Breakthroughs, Education and Outreach in Western New York
Patrick E. Lee Foundation
Role: Co-Investigator
$660,000
Journal Articles:
- Baker JG, Williams AJ, Wack DS, Miletich RS. (2013) Correlation of cognition and SPECT perfusion: easy Z score and SPM analysis of a pilot sample with cerebral small vessel disease. Dement Geriatr Cogn Disord (Aug), 36(5-6): 290-299.
- Farooq O, Lincoff NS, Saikali N, Prasad D, Miletich RS, Mechtler LL. (2012) Novel Treatment for Radiation Optic Neuropathy With Intravenous Bevacizumab. J Neuroophthalmol (Aug).
- Baker JG, Williams AJ, Ionita CC, Lee-Kwen P, Ching M, Miletich RS, Ching MI. (2012) Cerebral small vessel disease: cognition, mood, daily functioning, and imaging findings from a small pilot sample. Dement Geriatr Cogn Dis Extra (Jan), 2: 169-179.
- Klejbor I, Kucinski A, Wersinger SR, Corso T, Spodnik JH, Dziewiatkowski J, Morys J, Hesse RA, Rice KC, Miletich R, Stachowiak EK, Stachowiak MK, Miletich RS. (2009) Serotonergic hyperinnervation and effective serotonin blockade in an FGF receptor developmental model of psychosis. Schizophr Res (Sep), 113(2-3): 308-321.
- Miletich RS. (2009) Positron emission tomography for neurologists. Neurol Clin (Feb), 27(1): 61-88.
- Taheri SA, Ashraf H, Merhige M, Miletich RS, Satchidanand S, Malik C, Naughton J, Zhao Q. (2005) Myoangiogenesis after cell patch cardiomyoplasty and omentopexy in a patient with ischemic cardiomyopathy. Tex Heart Inst J (Jan), 32(4): 598-601.
- Dubey N, Miletich RS, Wasay M, Mechtler LL, Bakshi R. (2002) Role of fluorodeoxyglucose positron emission tomography in the diagnosis of neurosarcoidosis. J Neurol Sci (Dec), 205(1): 77-81.
- Meyer-Lindenberg A, Miletich RS, Kohn PD, Esposito G, Carson RE, Quarantelli M, Weinberger DR, Berman KF. (2002) Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia. Nat Neurosci (Mar), 5(3): 267-271.
- Kamran S, Bates V, Bakshi R, Wright P, Kinkel W, Miletich R, Miletich RS. (2000) Significance of hyperintense vessels on FLAIR MRI in acute stroke. Neurology (Jul), 55(2): 265-269.
- Fessler RD, Lanzino G, Guterman LR, Miletich RS, Lopes DK, Hopkins LN. (1999) Improved cerebral perfusion after stenting of a petrous carotid stenosis: technical case report. Neurosurgery (Sep), 45(3): 638-642.
- Bakshi R, Miletich RS, Henschel K, Shaikh ZA, Janardhan V, Wasay M, Stengel LM, Ekes R, Kinkel PR. (1999) Fatigue in multiple sclerosis: cross-sectional correlation with brain MRI findings in 71 patients. Neurology (Sep), 53(5): 1151-1153.
- Lanzino G, Fessler RD, Miletich RS, Guterman LR, Hopkins LN. (1999) Angioplasty and stenting of basilar artery stenosis: technical case report. Neurosurgery (Aug), 45(2): 404-407.
- Bakshi R, Miletich RS, Kinkel PR, Emmet ML, Kinkel WR. (1998) High-resolution fluorodeoxyglucose positron emission tomography shows both global and regional cerebral hypometabolism in multiple sclerosis. J Neuroimaging (Oct), 8(4): 228-234.
- Blesa R, Mohr E, Miletich RS, Hildebrand K, Sampson M, Chase TN. (1996) Cerebral metabolic changes in Alzheimer's disease: neurobehavioral patterns. Dementia (Sep), 7(5): 239-245.
- Nichelli P, Grafman J, Pietrini P, Clark K, Lee KY, Miletich R, Miletich RS. (1995) Where the brain appreciates the moral of a story. Neuroreport (Nov), 6(17): 2309-2313.
- Hiramatsu Y, Eckelman WC, Carrasquillo JA, Miletich RS, Valdez IH, Kurrasch RH, Macynski AA, Paik CH, Neumann RD, Baum BJ. (1995) Kinetic analysis of muscarinic receptors in human brain and salivary gland in vivo. Am J Physiol (Jun), 268(6 Pt): 1491-1499.
- Miletich RS, Bankiewicz KS, Quarantelli M, Plunkett RJ, Frank J, Kopin IJ, Di Chiro G. (1994) MRI detects acute degeneration of the nigrostriatal dopamine system after MPTP exposure in hemiparkinsonian monkeys. Ann Neurol (Jun), 35(6): 689-697.
- Miletich RS, Quarantelli M, Di Chiro G. (1994) Regional cerebral blood flow imaging with 99mTc-bicisate SPECT in asymmetric Parkinson's disease: studies with and without chronic drug therapy. J Cereb Blood Flow Metab (Jan), 14 Su: 106-114.
- Miletich RS, Comi G, Bankiewicz K, Plunkett R, Adams R, Di Chiro G, Kopin IJ. (1993) 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism and positron emission tomography after catechol-O-methyltransferase inhibition in normal and hemiparkinsonian monkeys. Brain Res (Oct), 626(1-2): 1-13.
- Mohr E, Mann UM, Miletich RS, Sampson M, Goldberg TE, Grimes JD, Chase TN. (1992) Neuropsychological and glucose metabolic profiles in asymmetric Parkinson's disease. Can J Neurol Sci (May), 19(2): 163-169.
- Ferrarese C, Guidotti A, Costa E, Miletich RS, Rice KC, de Costa BR, Fulham MJ, Di Chiro G. (1991) In vivo study of NMDA-sensitive glutamate receptor by fluorothienylcyclohexylpiperidine [correction of fluorothienylcycloexylpiperidine], a possible ligand for positron emission tomography. Neuropharmacology (Aug), 30(8): 899-905.
- Francavilla TL, Miletich RS, DeMichele D, Patronas NJ, Oldfield EH, Weintraub BD, Di Chiro G. (1991) Positron emission tomography of pituitary macroadenomas: hormone production and effects of therapies. Neurosurgery (Jun), 28(6): 826-833.
- Plunkett RJ, Bankiewicz KS, Cummins AC, Miletich RS, Schwartz JP, Oldfield EH. (1990) Long-term evaluation of hemiparkinsonian monkeys after adrenal autografting or cavitation alone. J Neurosurg (Dec), 73(6): 918-926.
- Bizzi A, Brooks RA, Brunetti A, Hill JM, Alger JR, Miletich RS, Francavilla TL, Di Chiro G. (1990) Role of iron and ferritin in MR imaging of the brain: a study in primates at different field strengths. Radiology (Oct), 177(1): 59-65.
- Goldstein DS, Chang PC, Eisenhofer G, Miletich R, Finn R, Bacher J, Kirk KL, Bacharach S, Kopin IJ, Miletich RS. (1990) Positron emission tomographic imaging of cardiac sympathetic innervation and function. Circulation (May), 81(5): 1606-1621.
- Francavilla TL, Miletich RS, Di Chiro G, Patronas NJ, Rizzoli HV, Wright DC. (1989) Positron emission tomography in the detection of malignant degeneration of low-grade gliomas. Neurosurgery (Jan), 24(1): 1-5.
- Eisenhofer G, Hovevey-Sion D, Kopin IJ, Miletich R, Kirk KL, Finn R, Goldstein DS, Miletich RS. (1989) Neuronal uptake and metabolism of 2- and 6-fluorodopamine: false neurotransmitters for positron emission tomographic imaging of sympathetically innervated tissues. J Pharmacol Exp Ther (Jan), 248(1): 419-427.
- Radulovacki M, Miletich RS, Green RD. (1982) N6 (L-phenylisopropyl) adenosine (L-PHA) increases slow-wave sleep (S2) and decreases wakefulness in rats. Brain Res (Aug), 246(1): 178-180.
- Radulovacki M, Wojcik WJ, Fornal C, Miletich R, Miletich RS. (1980) Elimination of REM sleep rebound in rats by alpha-adrenoreceptor blockers, phentolamine and phenoxybenzamine. Pharmacol Biochem Behav (Jul), 13(1): 51-55.
Books and Book Chapters:
- Hartley-McAndrew ME, Miletich RS, Farooq O. (2019) In: "Nuclear neurology of autism spectrum disorder". IOP Publishing Ltd., 6-1-6-13.
Abstracts:
- Miletich RS, Boudreau M, Li P, Li V. (2013) Ictal SPECT Activation in a Case of Gelastic Seizures Caused by a Low Grade Glioma in the Posteriolateral Temporal Lobe. Epilepsia, (Dec)
- Miletich RS, Wack DS. (2013) Alzheimer-like global brain impairment in newly diagnosed lung cancer. Society for Neuroscience, (Jan)
- Jaisani Z, Ramanathan M, Miletich R, Weinstock A. (2011) The Yield of FDG-PET in Patients with Temporal Lobe Epilepsy and Post Surgical Outcome. (Dec)
- Farooq O, Lincoff NS, Saikali, N, Prasad D, Miletich RS, Mechtler L. (2011) Novel Treatment for Radiation Optic Neuropathy with IV Bevacizumab. University of Buffalo 14th Annual Spring Clinical Research Day, (May)
- Farooq O, Lincoff NS, Saikali N, Prasad D, Miletich RS, Mechtler L. (2011) Novel Treatment for Radiation Optic Neuropathy with IV Bevacizumab. American Academy of Neurology, (Apr)
- Farooq O, Lincoff NS, Saikali N, Prasad D, Miletich RS, Mechtler L. (2011) Novel Treatment for Radiation Optic Neuropathy with IV Bevacizumab. North American Neuro-Ophthalmology Society, (Feb)
Professional Memberships:
- Organization for Human Brain Mapping (2003–present)
- Academy for Molecular Imaging (2002–present)
- Society of Nuclear Imaging in Drug Development (1999–2002)
- International Society for Cerebral Blood Flow and Metabolism, (1996–present)
- The Movement Disorder Society (1996–present)
- World Federation of Neurology (1995–present)
- American Society of Neuroimaging (1995–present)
- Institute for Clinical PET (1994–2002)
- Buffalo-Rochester-Syracuse Neuro-Oncology Research Group (1994–2000)
- Society of Nuclear Medicine; Brain Imaging Council (1990–present)
- International Brain Research Organization (1989–present)
- World Federation of Neuroscience (1989–present)
- New York Academy of Science (1988–present)
- American Association for the Advancement of Science (1986–present)
- American Academy of Neurology; Section on Neuroimaging Section on Movement Disorders (1983–present)
- Alpha Omega Alpha Honor Medical Society (1980–present)
- American Medical Association (1978–1991)
- Society for Neuroscience (1978–present)
- Phi Beta Kappa Honor Society, (1971–present)