Panayotis Thanos PhD
Panayotis Thanos
PhD
Professional Summary:
Research in my laboratory is focused upon distinct projects in the fields of Behavioral Neuropharmacology and Neuroimaging of Addiction and Substance Abuse. Our research is based on the notion that there are specific genetic and epigenetic vulnerabilities that significantly contribute to Reward Deficiency Syndrome (RDS) of which addiction is a part of.
My lab utilizes molecular, behavioral, and imaging (Positron Emission Tomography, MRI, CT, Autoradiograpjy) methods in animal models as well as how these models contribute to clinical data as part of several ongoing clinical translational studies.
Education and Training:
- Fellowship, Neuroscience and Neuroimaging of Drug Addiction, SUNY Stony Brook University (2000)
- PhD, Biomedical Sciences / Neuroscience, Eastern Virginia Medical School / Old Dominion Unversity (1997)
- MA, Biological Psychology, American University (1993)
- BS, Psychology, Queen's University (1990)
Employment:
- Senior Research Scientist, Department of Pharmacology & Toxicology, Jacobs School of Medicine and Biomedical Sciences, Department of Psychology, Clinical Research Institute on Addictions, University at Buffalo Jacobs School of Medicine & Biomedical Sciences
Awards and Honors:
- Investigator Travel Award (2015)
- Investigator Travel Award, RDS (2015)
- Investigator Travel Award, Imaging of Alcoholism. NIAAA (2006)
- US Department of Energy Science Mentor Award (2003)
- PSA Investigator Scholarship Award (1996)
- The Ralph D. Millard, M.D. Investigator Award. (1995)
- PSA Investigator Scholarship Award (1994)
- Massey Foundation Award
Research Expertise:
- Behavioral Neuropharmacology and Neuroimaging of Addiction: Dr. Thanos’ current research includes five major areas: (1) human and animal models to study the underlying genetic and neural mechanisms of increased vulnerability to alcohol abuse after bariatric surgery; (2) determining the chronic effects of methylphenidate on skeletal development and brain function, behavior (3) dissection of the role of Fatty Acid Binding Proteins on endocannabinoid signaling and function on addiction. (4) Role of exercise on molecular markers of addiction and interaction with genetics. (5) Biomarkers of prenatal exposure to nicotine and cannabis.
Grants and Sponsored Research:
- February 2022–August 2024
Prenatal Tobacco and Cannabis Exposure: A Translational Study
NIH
Role: Principal Investigator - October 2018–September 2023
Prenatal Tobacco and Cannabis Exposure: A Translational Study
NIDA
Role: Co-Principal Investigator
$690,000 - February 2022–January 2023
Response to cocaine following treatment with methylphenidate and fluoxetine.
NIH
Role: Co-Investigator
$60,000 - February 2022–February 2022
Iterative Learning and Automated Modular Platform for Optimum Nonaddictive Analgesic Discovery
NCATS
Role: Co-Investigator
$50,000 - February 2022–February 2022
Genetic and Psychosocial Risks of recidivism and alcohol abuse following bariatric surgery
Blue Sky
Role: Co-Principal Investigator
$30,000 - March 2018–March 2020
Fatty Acid Binding Protein - Mediated Control of Endocannabinoid Signaling and Drug Addiction
NIDA
Role: Co-Principal Investigator
$250,000 - September 2018–August 2019
Gastric Bypass, Brain Activity
NY Research Foundation
Role: Principal Investigator
$30,000 - February 2012–February 2019
Skeletal Effects of Methylphenidate
NICHD
Role: Co-Investigator
$440,000 - January 2016–January 2019
Increased Vulnerability to alcohol abuse after gastric bypass: Neural mechanisms
NIAAA
Role: Principal Investigator
$250,000 - June 2014–May 2018
Combined Cocaine and HIV Vaccine
NIDA
Role: Co-Investigator
$163,300 - July 2013–July 2015
The Dopamine Reward Circuit Activation Similarities between Food and Addiction
SUNYProvost
Role: Principal Investigator
$264,000
Journal Articles:
- Richer K, Hamilton J, Delis F, Martin C, Fricke D, Yao R, Sajjad M, Blum K, Hadjiargyrou M, Komatsu D, Thanos PK. (2022) Chronic treatment and abstinence from methylphenidate exposure dose-dependently changes glucose metabolism in the rat brain. Brain research (Apr), 1780: 147799.
- Rapp C, Hamilton J, Blum K, Thanos PK. (2022) The long-term interaction of diet and dopamine D2 gene expression on brain microglial activation. Psychiatry research. Neuroimaging (Mar), 320: 111430.
- Richardson B, Swenson S, Hamilton J, Leonard K, Delis F, Gold M, Blum K, Thanos PK. (2022) Chronic neuroleptic treatment combined with a high fat diet elevated [3H] flunitrazepam binding in the cerebellum. Progress in neuro-psychopharmacology & biological psychiatry (Jan), 112: 110407.
- Connor C, Hamilton J, Robison L, Hadjiargyrou M, Komatsu D, Thanos P. (2022) Abstinence from Chronic Methylphenidate Exposure Modifies Cannabinoid Receptor 1 Levels in the Brain in a Dose-dependent Manner. Current pharmaceutical design (Jan), 28(4): 331-338.
- Blum K, Bowirrat A, Braverman ER, Baron D, Cadet JL, Kazmi S, Elman I, Thanos PK, Badgaiyan RD, Downs WB, Bagchi D, Llanos-Gomez L, Gold MS. (2021) Reward Deficiency Syndrome (RDS): A Cytoarchitectural Common Neurobiological Trait of All Addictions. International journal of environmental research and public health (Nov), 18(21). doi:10.3390/ijerph182111529
- Moon C, Marion M, Thanos PK, Steiner H. (2021) Fluoxetine Potentiates Oral Methylphenidate-Induced Gene Regulation in the Rat Striatum. Molecular neurobiology (Oct), 58(10): 4856-4870. doi:10.1007/s12035-021-02466-y
- Blum K, Gold MS, Llanos-Gomez L, Jalali R, Thanos PK, Bowirrat A, Downs WB, Bagchi D, Braverman ER, Baron D, Roy AK, Badgaiyan RD. (2021) Hypothesizing Nutrigenomic-Based Precision Anti-Obesity Treatment and Prophylaxis: Should We Be Targeting Sarcopenia Induced Brain Dysfunction?. International journal of environmental research and public health (Sep), 18(18). doi:10.3390/ijerph18189774
- Blum K, Modestino EJ, Baron D, Brewer R, Thanos P, Elman I, Badgaiyan RD, Downs BW, Bagchi D, McLaughlin T, Bowirrat A, Roy AK, Gold MS. (2021) Endorphinergic Enhancement Attenuation of Post-traumatic Stress Disorder (PTSD) via Activation of Neuro-immunological Function in the Face of a Viral Pandemic. Current psychopharmacology (Aug), 10(2): 86-97. doi:10.2174/2211556009999210104221215
- Moran M, Blum K, Ponce JV, Lott L, Gondré-Lewis MC, Badgaiyan S, Brewer R, Downs BW, Fynman P, Weingarten A, Cadet JL, Smith DE, Baron D, Thanos PK, Modestino EJ, Badgaiyan RD, Elman I, Gold MS. (2021) High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial. Molecular neurobiology (Jul), 58(7): 3335-3346. doi:10.1007/s12035-021-02312-1
- Maredia M, Hamilton J, Thanos PK. (2021) A high-fat diet, but not haloperidol or olanzapine administration, increases activated microglial expression in the rat brain. Neuroscience letters (Jul), 757: 135976.
- Blum K, Kazmi S, Modestino EJ, Downs BW, Bagchi D, Baron D, McLaughlin T, Green R, Jalali R, Thanos PK, Elman I, Badgaiyan RD, Bowirrat A, Gold MS. (2021) A Novel Precision Approach to Overcome the "Addiction Pandemic" by Incorporating Genetic Addiction Risk Severity (GARS) and Dopamine Homeostasis Restoration. Journal of personalized medicine (Mar), 11(3). doi:10.3390/jpm11030212
- Blum K, Bowirrat A, Gondre Lewis MC, Simpatico TA, Ceccanti M, Steinberg B, Modestino EJ, Thanos PK, Baron D, McLaughlin T, Brewer R, Badgaiyan RD, Ponce JV, Lott L, Gold MS. (2021) Exploration of Epigenetic State Hyperdopaminergia (Surfeit) and Genetic Trait Hypodopaminergia (Deficit) During Adolescent Brain Development. Current psychopharmacology (Feb), 10. doi:10.2174/2211556010666210215155509
- Blum K, Raza A, Schultz T, Jalali R, Green R, Brewer R, Thanos PK, McLaughlin T, Baron D, Bowirrat A, Elman I, Downs BW, Bagchi D, Badgaiyan RD. (2021) Should We Embrace the Incorporation of Genetically Guided "Dopamine Homeostasis" in the Treatment of Reward Deficiency Syndrome (RSD) as a Frontline Therapeutic Modality?. Acta scientific neurology (Feb), 4(2): 17-24.
- Jalloh K, Roeder N, Hamilton J, Delis F, Hadjiargyrou M, Komatsu D, Thanos PK. (2021) Chronic oral methylphenidate treatment in adolescent rats promotes dose-dependent effects on NMDA receptor binding. Life sciences (Jan), 264: 118708.
- McGregor M, Hamilton J, Hajnal A, Thanos PK. (2020) Roux-en-Y gastric bypass increases GABA-A receptor levels in regions of the rat brain involved in object recognition memory and perceptual acuity. Physiology & behavior (Oct), 224: 113053.
- Rahman N, Mihalkovic A, Geary O, Haffey R, Hamilton J, Thanos PK. (2020) Chronic aerobic exercise: Autoradiographic assessment of GABA(a) and mu-opioid receptor binding in adult rats. Pharmacology, biochemistry, and behavior (Sep), 196: 172980.
- McGregor M, Richer K, Ananth M, Thanos PK. (2020) The functional networks of a novel environment: Neural activity mapping in awake unrestrained rats using positron emission tomography. Brain and behavior (Aug), 10(8): e01646. doi:10.1002/brb3.1646
- Swenson S, Blum K, McLaughlin T, Gold MS, Thanos PK. (2020) The therapeutic potential of exercise for neuropsychiatric diseases: A review. Journal of the neurological sciences (May), 412: 116763.
- Kalinowski L, Connor C, Somanesan R, Carias E, Richer K, Smith L, Martin C, Mackintosh M, Popoola D, Hadjiargyrou M, Komatsu DE, Thanos PK. (2020) Brief and extended abstinence from chronic oral methylphenidate treatment produces reversible behavioral and physiological effects. Developmental psychobiology (Mar), 62(2): 170-180. doi:10.1002/dev.21902
- Edwards D, Roy AK, Boyett B, Badgaiyan RD, Thanos PK, Baron D, Hauser M, Badgaiyan S, Brewer R, Siwicki DB, Downs W, Smith DE, Blum K. (2020) Addiction by Any Other Name is Still Addiction: Embracing Molecular Neurogenetic/Epigenetic Basis of Reward Deficiency. Journal of addiction science (Jan), 6(1): 1-4.
- Fried L, Modestino EJ, Siwicki D, Lott L, Thanos PK, Baron D, Badgaiyan RD, Ponce JV, Giordano J, Downs WB, Gondré-Lewis MC, Bruce S, Braverman ER, Boyett B, Blum K. (2020) Hypodopaminergia and "Precision Behavioral Management" (PBM): It is a Generational Family Affair. Current pharmaceutical biotechnology (Jan), 21(6): 528-541.
- Blum K, Gondré-Lewis MC, Modestino EJ, Lott L, Baron D, Siwicki D, McLaughlin T, Howeedy A, Krengel MH, Oscar-Berman M, Thanos PK, Elman I, Hauser M, Fried L, Bowirrat A, Badgaiyan RD. (2019) Understanding the Scientific Basis of Post-traumatic Stress Disorder (PTSD): Precision Behavioral Management Overrides Stigmatization. Molecular neurobiology (Nov), 56(11): 7836-7850. doi:10.1007/s12035-019-1600-8
- Blum K, Baron D, Hauser M, Henriksen S, Thanos PK, Black C, Siwicki D, Modestino EJ, Downs BW, Badgaiyan S, Simpatico TA, Boyett B, Badgaiyan RD. (2019) Americas' opioid/psychostimulant epidemic would benefit from general population early identification of genetic addiction risk especially in children of alcoholics (COAs). Journal of systems and integrative neuroscience (Oct), 5(2): 1-3.
- Swenson S, Hamilton J, Robison L, Thanos PK. (2019) Chronic aerobic exercise: Lack of effect on brain CB1 receptor levels in adult rats. Life sciences (Aug), 230: 84-88.
- Ananth M, Hetelekides EM, Hamilton J, Thanos PK. (2019) Dopamine D4 receptor gene expression plays important role in extinction and reinstatement of cocaine-seeking behavior in mice. Behavioural brain research (Jun), 365: 1-6.
- McGregor M, Hamilton J, Hajnal A, Thanos PK. (2019) Roux-en-Y gastric bypass in rat reduces mu-opioid receptor levels in brain regions associated with stress and energy regulation. PloS one (Jan), 14(6): e0218680. doi:10.1371/journal.pone.0218680
- Carias E, Fricke D, Vijayashanthar A, Smith L, Somanesan R, Martin C, Kalinowski L, Popoola D, Hadjiargyrou M, Komatsu DE, Thanos PK, Thanos P. (2019) Weekday-only chronic oral methylphenidate self-administration in male rats: Reversibility of the behavioral and physiological effects. Behav Brain Res (Jan), 356: 189-196.
- Carias E, Hamilton J, Robison LS, Delis F, Eiden R, Quattrin T, Hadjiargyrou M, Komatsu D, Thanos PK, Thanos P. (2018) Chronic oral methylphenidate treatment increases microglial activation in rats. J Neural Transm (Vienna) (Dec), 125(12): 1867-1875.
- Robison LS, Alessi L, Thanos PK, Thanos P. (2018) Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference. Behav Brain Res (Nov), 353: 176-184.
- Blum K, Jacobs W, Modestino EJ, DiNubile N, Baron D, McLaughlin T, Siwicki D, Elman I, Moran M, Braverman ER, Thanos PK, Badgaiyan RD, Thanos P. (2018) Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic. SEJ Surg Pain (Oct), 1(1): 1-11.
- Martin C, Fricke D, Vijayashanthar A, Lowinger C, Koutsomitis D, Popoola D, Hadjiargyrou M, Komatsu DE, Thanos PK, Thanos P. (2018) Recovery from behavior and developmental effects of chronic oral methylphenidate following an abstinence period. Pharmacol Biochem Behav (Sep), 172: 22-32.
- Hamilton J, Koumas C, Clavin BH, Marion M, Figueiredo A, Gonzalez S, O'Rourke JR, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK. (2018) Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time. Behavioural pharmacology (Sep), 29(6): 503-508. doi:10.1097/FBP.0000000000000402
- Robison LS, Swenson S, Hamilton J, Thanos PK, Thanos P. (2018) Exercise Reduces Dopamine D1R and Increases D2R in Rats: Implications for Addiction. Med Sci Sports Exerc (Aug), 50(8): 1596-1602.
- Blum K, Modestino EJ, Badgaiyan RD, Baron D, Thanos PK, Elman I, Siwicki D, Febo M, Gold MS, Thanos P. (2018) Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse. EC Psychol Psychiatr (Aug), 7(8): 564-579.
- Hamilton J, Swenson S, Hajnal A, Thanos PK, Thanos P. (2018) Roux-en-Y gastric bypass surgery normalizes dopamine D1, D2, and DAT levels. Synapse (Jul).
- Hamilton J, Marion M, Figueiredo A, Clavin BH, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK. (2018) Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels. Synapse (New York, N.Y.) (Jun), 72(6): e22031. doi:10.1002/syn.22031
- Michaelides M, Miller ML, Egervari G, Primeaux SD, Gomez JL, Ellis RJ, Landry JA, Szutorisz H, Hoffman AF, Lupica CR, Loos RJF, Thanos PK, Bray GA, Neumaier JF, Zachariou V, Wang GJ, Volkow ND, Hurd YL, Thanos P. (2018) Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity. Mol Psychiatry (Jun).
- Haj-Dahmane S, Shen RY, Elmes MW, Studholme K, Kanjiya MP, Bogdan D, Thanos PK, Miyauchi JT, Tsirka SE, Deutsch DG, Kaczocha M. (2018) Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses. Proceedings of the National Academy of Sciences of the United States of America (Mar), 115(13): 3482-3487. doi:10.1073/pnas.1721339115
- Thanos PK, Zhuo J, Robison L, Kim R, Ananth M, Choai I, Grunseich A, Grissom NM, George R, Delis F, Reyes TM, Thanos P. (2018) Suboptimal maternal diets alter mu opioid receptor and dopamine type 1 receptor binding but exert no effect on dopamine transporters in the offspring brain. Int J Dev Neurosci (Feb), 64: 21-28.
- Blum K, Thanos PK, Wang GJ, Febo M, Demetrovics Z, Modestino EJ, Braverman ER, Baron D, Badgaiyan RD, Gold MS, Thanos P. (2018) The Food and Drug Addiction Epidemic: Targeting Dopamine Homeostasis. Curr Pharm Des (Feb), 23(39): 6050-6061.
- Blum K, Modestino EJ, Gondre-Lewis M, Chapman EJ, Neary J, Siwicki D, Baron D, Hauser M, Smith DE, Roy AK, Thanos PK, Steinberg B, McLaughlin T, Fried L, Barh D, Dunston GA, Badgaiyan RD, Thanos P. (2018) The Benefits of Genetic Addiction Risk Score (GARSâ„¢) Testing in Substance Use Disorder (SUD). Int J Genom Data Min (Jan), 2018(1).
- Blum K, Gondré-Lewis MC, Baron D, Thanos PK, Braverman ER, Neary J, Elman I, Badgaiyan RD. (2018) Introducing Precision Addiction Management of Reward Deficiency Syndrome, the Construct That Underpins All Addictive Behaviors. Frontiers in psychiatry (Jan), 9: 548. doi:10.3389/fpsyt.2018.00548
- Uddin SMZ, Robison LS, Fricke D, Chernoff E, Hadjiargyrou M, Thanos PK, Komatsu DE, Thanos P. (2018) Methylphenidate regulation of osteoclasts in a dose- and sex-dependent manner adversely affects skeletal mechanical integrity. Sci Rep (Jan), 8(1): 1515-1515.
- Blum K, Chen ALC, Thanos PK, Febo M, Demetrovics Z, Dushaj K, Kovoor A, Baron D, Smith DE, Roy AK, Fried L, Chen TJH, Chapman E, Modestino EJ, Steinberg B, Badgaiyan RD, Thanos P. (2018) Genetic addiction risk score (GARS) â„¢, a predictor of vulnerability to opioid dependence. Front Biosci (Elite Ed) (Jan), 10: 175-196.
- McLaughlin T, Blum K, Steinberg B, Siwicki D, Campione J, Badgaiyan RD, Braverman ER, Modestino EJ, Gondré-Lewis MC, Baron D, Mash DC, Giordano J, Thanos PK, Thanos P. (2017) Hypothesizing Las Vegas and Sutherland Springs Mass Shooters Suffer from Reward Deficiency Syndrome: "Born Bad". J Reward Defic Syndr Addict Sci (Dec), 3(2): 28-31.
- Delis F, Rosko L, Shroff A, Leonard KE, Thanos PK, Thanos P. (2017) Oral haloperidol or olanzapine intake produces distinct and region-specific increase in cannabinoid receptor levels that is prevented by high fat diet. Prog Neuropsychopharmacol Biol Psychiatry (Oct), 79(Pt B): 268-280.
- Robison LS, Ananth M, Hadjiargyrou M, Komatsu DE, Thanos PK, Thanos P. (2017) Chronic oral methylphenidate treatment reversibly increases striatal dopamine transporter and dopamine type 1 receptor binding in rats. J Neural Transm (Vienna) (May), 124(5): 655-667.
- Febo M, Blum K, Badgaiyan RD, Perez PD, Colon-Perez LM, Thanos PK, Ferris CF, Kulkarni P, Giordano J, Baron D, Gold MS, Thanos P. (2017) Enhanced functional connectivity and volume between cognitive and reward centers of naïve rodent brain produced by pro-dopaminergic agent KB220Z. PLoS One (Apr), 12(4): 0174774-0174774.
- Robison LS, Michaelos M, Gandhi J, Fricke D, Miao E, Lam CY, Mauceri A, Vitale M, Lee J, Paeng S, Komatsu DE, Hadjiargyrou M, Thanos PK, Thanos P. (2017) Sex Differences in the Physiological and Behavioral Effects of Chronic Oral Methylphenidate Treatment in Rats. Front Behav Neurosci (Mar), 11: 53-53.
- Thanos PK, Restif C, O'Rourke JR, Lam CY, Metaxas D, Thanos P. (2017) Mouse Social Interaction Test (MoST): a quantitative computer automated analysis of behavior. J Neural Transm (Vienna) (Jan), 124(1): 3-11.
- Thanos PK, Kim R, Delis F, Rocco MJ, Cho J, Volkow ND, Thanos P. (2017) Effects of chronic methamphetamine on psychomotor and cognitive functions and dopamine signaling in the brain. Behav Brain Res (Jan), 320: 282-290.
- Febo M, Blum K, Badgaiyan RD, Baron D, Thanos PK, Colon-Perez LM, Demortrovics Z, Gold MS, Thanos P. (2017) Dopamine homeostasis: brain functional connectivity in reward deficiency syndrome. Front Biosci (Landmark Ed) (Jan), 22: 669-691.
- Figueiredo A, Hamilton J, Marion M, Blum K, Kaczocha M, Haj-Dahmane S, Deutsch D, Thanos PK. (2017) Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice. Journal of reward deficiency syndrome and addiction science (Jan), 3(2): 21-27.
- Blum K, Gold M, Demetrovics Z, Archer T, Thanos PK, Baron D, Badgaiyan RD, Thanos P. (2017) Substance use disorder a bio-directional subset of reward deficiency syndrome. Front Biosci (Landmark Ed) (Jan), 22: 1534-1548.
- Blum K, Badgaiyan RD, Braverman ER, Dushaj K, Li M, Thanos PK, Demetrovics Z, Febo M, Thanos P. (2016) Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. J Reward Defic Syndr Addict Sci (Jun), 2(1): 14-21.
- Thanos PK, Kim R, Delis F, Ananth M, Chachati G, Rocco MJ, Masad I, Muniz JA, Grant SC, Gold MS, Cadet JL, Volkow ND, Thanos P. (2016) Chronic Methamphetamine Effects on Brain Structure and Function in Rats. PLoS One (Jun), 11(6): 0155457-0155457.
- Thanos PK, Hamilton J, O'Rourke JR, Napoli A, Febo M, Volkow ND, Blum K, Gold M, Thanos P. (2016) Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior. Oncotarget (Apr), 7(15): 19111-19123.
- Roux A, Jackson SN, Muller L, Barbacci D, O'Rourke J, Thanos PK, Volkow ND, Balaban C, Schultz JA, Woods AS, Thanos P. (2016) Ethanol Induced Brain Lipid Changes in Mice Assessed by Mass Spectrometry. ACS Chem Neurosci (Jan), 7(8): 1148-1156.
- Thanos PK, Malave L, Delis F, Mangine P, Kane K, Grunseich A, Vitale M, Greengard P, Volkow ND, Thanos P. (2016) Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice. Synapse (Jan), 70(7): 293-301.
- Thanos PK, Clavin BH, Hamilton J, O'Rourke JR, Maher T, Koumas C, Miao E, Lankop J, Elhage A, Haj-Dahmane S, Deutsch D, Kaczocha M. (2016) Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26. Frontiers in psychiatry (Jan), 7: 54. doi:10.3389/fpsyt.2016.00054
- Blum K, Febo M, Thanos PK, Baron D, Fratantonio J, Gold M, Thanos P. (2015) Clinically Combating Reward Deficiency Syndrome (RDS) with Dopamine Agonist Therapy as a Paradigm Shift: Dopamine for Dinner?. Mol Neurobiol (Dec), 52(3): 1862-1869.
- Kaczocha M, Glaser ST, Maher T, Clavin B, Hamilton J, O'Rourke J, Rebecchi M, Puopolo M, Owada Y, Thanos PK, Thanos P. (2015) Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms. Mol Pain (Aug), 11: 52-52.
- Blum K, Thanos PK, Badgaiyan RD, Febo M, Oscar-Berman M, Fratantonio J, Demotrovics Z, Gold MS, Thanos P. (2015) Neurogenetics and gene therapy for reward deficiency syndrome: are we going to the Promised Land?. Expert Opin Biol Ther (Jul), 15(7): 973-985.
- Thanos PK, Roushdy K, Sarwar Z, Rice O, Ashby CR, Grandy DK, Thanos P. (2015) The effect of dopamine D4 receptor density on novelty seeking, activity, social interaction, and alcohol binge drinking in adult mice. Synapse (Jul), 69(7): 356-364.
- Thanos PK, Michaelides M, Subrize M, Miller ML, Bellezza R, Cooney RN, Leggio L, Wang GJ, Rogers AM, Volkow ND, Hajnal A, Thanos P. (2015) Roux-en-Y Gastric Bypass Alters Brain Activity in Regions that Underlie Reward and Taste Perception. PLoS One (Jun), 10(6): 0125570-0125570.
- Delis F, Rombola C, Bellezza R, Rosko L, Grandy DK, Volkow ND, Thanos PK, Thanos P. (2015) Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters. Front Behav Neurosci (May), 9: 118-118.
- Volkow ND, Wang GJ, Logan J, Alexoff D, Fowler JS, Thanos PK, Wong C, Casado V, Ferre S, Tomasi D, Thanos P. (2015) Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain. Transl Psychiatry (Apr), 5: 549-549.
- Thanos PK, Robison LS, Steier J, Hwang YF, Cooper T, Swanson JM, Komatsu DE, Hadjiargyrou M, Volkow ND, Thanos P. (2015) A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior. Pharmacol Biochem Behav (Apr), 131: 143-153.
- Roux A, Muller L, Jackson SN, Baldwin K, Womack V, Pagiazitis JG, O'Rourke JR, Thanos PK, Balaban C, Schultz JA, Volkow ND, Woods AS, Thanos P. (2015) Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents. ACS Chem Neurosci (Feb), 6(2): 247-259.
- Blum K, Thanos PK, Oscar-Berman M, Febo M, Baron D, Badgaiyan RD, Gardner E, Demetrovics Z, Fahlke C, Haberstick BC, Dushaj K, Gold MS, Thanos P. (2015) Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction. J Reward Defic Syndr (Jan), 1(3): 95-104.
- Blum K, Thanos PK, Gold MS, Thanos P. (2014) Dopamine and glucose, obesity, and reward deficiency syndrome. Front Psychol (Sep), 5: 919-919.
- Cassataro D, Bergfeldt D, Malekian C, Van Snellenberg JX, Thanos PK, Fishell G, Sjulson L. (2014) Reverse pharmacogenetic modulation of the nucleus accumbens reduces ethanol consumption in a limited access paradigm. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (Jan), 39(2): 283-90. doi:10.1038/npp.2013.184
- Michaelides M, Anderson SA, Ananth M, Smirnov D, Thanos PK, Neumaier JF, Wang GJ, Volkow ND, Hurd YL. (2013) Whole-brain circuit dissection in free-moving animals reveals cell-specific mesocorticolimbic networks. The Journal of clinical investigation (Dec), 123(12): 5342-50. doi:10.1172/JCI72117
- Anderson SA, Michaelides M, Zarnegar P, Ren Y, Fagergren P, Thanos PK, Wang GJ, Bannon M, Neumaier JF, Keller E, Volkow ND, Hurd YL. (2013) Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression. The Journal of clinical investigation (Dec), 123(12): 5334-41. doi:10.1172/JCI70395
- Saint-Preux F, Bores LR, Tulloch I, Ladenheim B, Kim R, Thanos PK, Volkow ND, Cadet JL. (2013) Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of rats. Neuroscience (Jul), 243: 89-96. doi:10.1016/j.neuroscience.2013.03.052
- Michaelides M, Miller ML, Subrize M, Kim R, Robison L, Hurd YL, Wang GJ, Volkow ND, Thanos PK. (2013) Limbic activation to novel versus familiar food cues predicts food preference and alcohol intake. Brain research (May), 1512: 37-44. doi:10.1016/j.brainres.2013.03.006
- Thanos P, Delis F, Rosko L, Volkow ND. (2013) Passive Response to Stress in Adolescent Female and Adult Male Mice after Intermittent Nicotine Exposure in Adolescence. J Addict Res Ther (Apr), Suppl: 007-007.
- Thanos PK, Robison LS, Robinson JK, Michaelides M, Wang GJ, Volkow ND, Thanos P. (2013) Obese rats with deficient leptin signaling exhibit heightened sensitivity to olfactory food cues. Synapse (Apr), 67(4): 171-178.
- Thanos PK, Robison L, Nestler EJ, Kim R, Michaelides M, Lobo MK, Volkow ND. (2013) Mapping brain metabolic connectivity in awake rats with µPET and optogenetic stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience (Apr), 33(15): 6343-9. doi:10.1523/JNEUROSCI.4997-12.2013
- Thanos PK, Stamos J, Robison LS, Heyman G, Tucci A, Wang GJ, Robinson JK, Anderson BJ, Volkow ND, Thanos P. (2013) Daily treadmill exercise attenuates cocaine cue-induced reinstatement and cocaine induced locomotor response but increases cocaine-primed reinstatement. Behav Brain Res (Feb), 239: 8-14.
- Delis F, Thanos PK, Rombola C, Rosko L, Grandy D, Wang GJ, Volkow ND, Thanos P. (2013) Chronic mild stress increases alcohol intake in mice with low dopamine D2 receptor levels. Behav Neurosci (Feb), 127(1): 95-105.
- Polston JE, Pritchett CE, Tomasko JM, Rogers AM, Leggio L, Thanos PK, Volkow ND, Hajnal A. (2013) Roux-en-Y gastric bypass increases intravenous ethanol self-administration in dietary obese rats. PloS one (Jan), 8(12): e83741. doi:10.1371/journal.pone.0083741
- Grady DL, Thanos PK, Corrada MM, Barnett JC, Ciobanu V, Shustarovich D, Napoli A, Moyzis AG, Grandy D, Rubinstein M, Wang GJ, Kawas CH, Chen C, Dong Q, Wang E, Volkow ND, Moyzis RK. (2013) DRD4 genotype predicts longevity in mouse and human. The Journal of neuroscience : the official journal of the Society for Neuroscience (Jan), 33(1): 286-91. doi:10.1523/JNEUROSCI.3515-12.2013
- Thanos PK, Subrize M, Delis F, Cooney RN, Culnan D, Sun M, Wang GJ, Volkow ND, Hajnal A, Thanos P. (2012) Gastric bypass increases ethanol and water consumption in diet-induced obese rats. Obes Surg (Dec), 22(12): 1884-1892.
- Alzghoul L, Bortolato M, Delis F, Thanos PK, Darling RD, Godar SC, Zhang J, Grant S, Wang GJ, Simpson KL, Chen K, Volkow ND, Lin RC, Shih JC, Thanos P. (2012) Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice. Neuropharmacology (Dec), 63(7): 1208-1217.
- Hajnal A, Zharikov A, Polston JE, Fields MR, Tomasko J, Rogers AM, Volkow ND, Thanos PK, Thanos P. (2012) Alcohol reward is increased after Roux-en-Y gastric bypass in dietary obese rats with differential effects following ghrelin antagonism. PLoS One (Nov), 7(11): 49121-49121.
- Wang GJ, Smith L, Volkow ND, Telang F, Logan J, Tomasi D, Wong CT, Hoffman W, Jayne M, Alia-Klein N, Thanos P, Fowler JS. (2012) Decreased dopamine activity predicts relapse in methamphetamine abusers. Mol Psychiatry (Sep), 17(9): 918-925.
- Michaelides M, Thanos PK, Volkow ND, Wang GJ, Thanos P. (2012) Dopamine-related frontostriatal abnormalities in obesity and binge-eating disorder: emerging evidence for developmental psychopathology. Int Rev Psychiatry (Jun), 24(3): 211-218.
- Komatsu DE, Thanos PK, Mary MN, Janda HA, John CM, Robison L, Ananth M, Swanson JM, Volkow ND, Hadjiargyrou M, Thanos P. (2012) Chronic exposure to methylphenidate impairs appendicular bone quality in young rats. Bone (Jun), 50(6): 1214-1222.
- Volkow ND, Tomasi D, Wang GJ, Telang F, Fowler JS, Logan J, Benveniste H, Kim R, Thanos PK, Ferré S, Thanos P. (2012) Evidence that sleep deprivation downregulates dopamine D2R in ventral striatum in the human brain. J Neurosci (May), 32(19): 6711-6717.
- Delis F, Benveniste H, Xenos M, Grandy D, Wang GJ, Volkow ND, Thanos PK. (2012) Loss of dopamine D2 receptors induces atrophy in the temporal and parietal cortices and the caudal thalamus of ethanol-consuming mice. Alcoholism, clinical and experimental research (May), 36(5): 815-25.
- Michaelides M, Thanos PK, Kim R, Cho J, Ananth M, Wang GJ, Volkow ND. (2012) PET imaging predicts future body weight and cocaine preference. NeuroImage (Jan), 59(2): 1508-13. doi:10.1016/j.neuroimage.2011.08.028
- Michaelides M, Thanos PK, Volkow ND, Wang GJ. (2012) Translational neuroimaging in drug addiction and obesity. ILAR journal (Jan), 53(1): 59-68.
- Thanos PK, Subrize M, Lui W, Puca Z, Ananth M, Michaelides M, Wang GJ, Volkow ND. (2011) D-cycloserine facilitates extinction of cocaine self-administration in C57 mice. Synapse (New York, N.Y.) (Oct), 65(10): 1099-105. doi:10.1002/syn.20944
- Thanos PK, Bermeo C, Wang GJ, Volkow ND. (2011) D-cycloserine facilitates extinction of cocaine self-administration in rats. Synapse (New York, N.Y.) (Sep), 65(9): 938-44. doi:10.1002/syn.20922
- Vakalopoulos I, Thanos P, Gkotsos G, Radopoulos D. (2011) Are vascular disorders a common cause of erectile dysfunction in non hypogonadal, non neuropsychiatric patients?. Hippokratia (Jul), 15(3): 244-246.
- Thanos PK, Cho J, Kim R, Michaelides M, Primeaux S, Bray G, Wang GJ, Volkow ND. (2011) Bromocriptine increased operant responding for high fat food but decreased chow intake in both obesity-prone and resistant rats. Behavioural brain research (Feb), 217(1): 165-70. doi:10.1016/j.bbr.2010.10.027
- Thanos PK, Gopez V, Delis F, Michaelides M, Grandy DK, Wang GJ, Kunos G, Volkow ND. (2011) Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. Alcoholism, clinical and experimental research (Jan), 35(1): 19-27. doi:10.1111/j.1530-0277.2010.01318.x
- Zhang S, Huang J, Uzunbas M, Shen T, Delis F, Huang X, Volkow N, Thanos P, Metaxas DN. (2011) 3D segmentation of rodent brain structures using hierarchical shape priors and deformable models. Med Image Comput Comput Assist Interv (Jan), 14(Pt 3): 611-618.
- Thanos PK, Tucci A, Stamos J, Robison L, Wang GJ, Anderson BJ, Volkow ND, Thanos P. (2010) Chronic forced exercise during adolescence decreases cocaine conditioned place preference in Lewis rats. Behav Brain Res (Dec), 215(1): 77-82.
- Thanos PK, Kim R, Cho J, Michaelides M, Anderson BJ, Primeaux SD, Bray GA, Wang GJ, Robinson JK, Volkow ND, Thanos P. (2010) Obesity-resistant S5B rats showed greater cocaine conditioned place preference than the obesity-prone OM rats. Physiol Behav (Dec), 101(5): 713-718.
- Volkow ND, Fowler JS, Wang GJ, Shumay E, Telang F, Thanos PK, Alexoff D. (2010) Distribution and pharmacokinetics of methamphetamine in the human body: clinical implications. PloS one (Dec), 5(12): e15269. doi:10.1371/journal.pone.0015269
- Michaelides M, Pascau J, Gispert JD, Delis F, Grandy DK, Wang GJ, Desco M, Rubinstein M, Volkow ND, Thanos PK, Thanos P. (2010) Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate. Eur J Neurosci (Aug), 32(4): 668-676.
- Pfaffly J, Michaelides M, Wang GJ, Pessin JE, Volkow ND, Thanos PK, Thanos P. (2010) Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice. Synapse (Jul), 64(7): 503-510.
- Thanos PK, Bermeo C, Rubinstein M, Suchland KL, Wang GJ, Grandy DK, Volkow ND, Thanos P. (2010) Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors. J Psychopharmacol (Jun), 24(6): 897-904.
- Thanos PK, Habibi R, Michaelides M, Patel UB, Suchland K, Anderson BJ, Robinson JK, Wang GJ, Grandy DK, Volkow ND, Thanos P. (2010) Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine. Behav Brain Res (Mar), 207(2): 508-511.
- Thanos PK, Ivanov I, Robinson JK, Michaelides M, Wang GJ, Swanson JM, Newcorn JH, Volkow ND, Thanos P. (2010) Dissociation between spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats in baseline performance and methylphenidate response on measures of attention, impulsivity and hyperactivity in a Visual Stimulus Position Discrimination Task. Pharmacol Biochem Behav (Jan), 94(3): 374-379.
- Thanos PK, Bermeo C, Wang GJ, Volkow ND, Thanos P. (2009) D-cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57bL/c mice. Behav Brain Res (May), 199(2): 345-349.
- Wang GJ, Volkow ND, Thanos PK, Fowler JS, Thanos P. (2009) Imaging of brain dopamine pathways: implications for understanding obesity. J Addict Med (Mar), 3(1): 8-18.
- Wang GJ, Volkow ND, Telang F, Jayne M, Ma Y, Pradhan K, Zhu W, Wong CT, Thanos PK, Geliebter A, Biegon A, Fowler JS, Thanos P. (2009) Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation. Proc Natl Acad Sci U S A (Jan), 106(4): 1249-1254.
- Radopoulos D, Vakalopoulos I, Thanos P. (2009) Preputial graft in penile curvature correction: preliminary results. Int J Impot Res (Jan), 21(1): 82-87.
- Davis LM, Michaelides M, Cheskin LJ, Moran TH, Aja S, Watkins PA, Pei Z, Contoreggi C, McCullough K, Hope B, Wang GJ, Volkow ND, Thanos PK. (2009) Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity. Neuroendocrinology (Jan), 89(2): 152-62. doi:10.1159/000170586
- Volkow ND, Wang GJ, Telang F, Fowler JS, Goldstein RZ, Alia-Klein N, Logan J, Wong C, Thanos PK, Ma Y, Pradhan K. (2009) Inverse association between BMI and prefrontal metabolic activity in healthy adults. Obesity (Silver Spring, Md.) (Jan), 17(1): 60-5. doi:10.1038/oby.2008.469
- Volkow ND, Wang GJ, Telang F, Fowler JS, Thanos PK, Logan J, Alexoff D, Ding YS, Wong C, Ma Y, Pradhan K. (2008) Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors. NeuroImage (Oct), 42(4): 1537-43. doi:10.1016/j.neuroimage.2008.06.002
- Thanos PK, Ramalhete RC, Michaelides M, Piyis YK, Wang GJ, Volkow ND. (2008) Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regions. Synapse (New York, N.Y.) (Sep), 62(9): 637-42. doi:10.1002/syn.20531
- Vinod KY, Yalamanchili R, Thanos PK, Vadasz C, Cooper TB, Volkow ND, Hungund BL. (2008) Genetic and pharmacological manipulations of the CB(1) receptor alter ethanol preference and dependence in ethanol preferring and nonpreferring mice. Synapse (New York, N.Y.) (Aug), 62(8): 574-81. doi:10.1002/syn.20533
- Volkow ND, Wang GJ, Telang F, Fowler JS, Logan J, Wong C, Ma J, Pradhan K, Tomasi D, Thanos PK, Ferré S, Jayne M. (2008) Sleep deprivation decreases binding of [11C]raclopride to dopamine D2/D3 receptors in the human brain. The Journal of neuroscience : the official journal of the Society for Neuroscience (Aug), 28(34): 8454-61. doi:10.1523/JNEUROSCI.1443-08.2008
- Thanos PK, Michaelides M, Umegaki H, Volkow ND. (2008) D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. Synapse (New York, N.Y.) (Jul), 62(7): 481-6. doi:10.1002/syn.20523
- Thanos PK, Michaelides M, Gispert JD, Pascau J, Soto-Montenegro ML, Desco M, Wang R, Wang GJ, Volkow ND. (2008) Differences in response to food stimuli in a rat model of obesity: in-vivo assessment of brain glucose metabolism. International journal of obesity (2005) (Jul), 32(7): 1171-9. doi:10.1038/ijo.2008.50
- Thanos PK, Michaelides M, Ho CW, Wang GJ, Newman AH, Heidbreder CA, Ashby CR, Gardner EL, Volkow ND, Thanos P. (2008) The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity. Pharmacol Biochem Behav (Jun), 89(4): 499-507.
- Thanos PK, Michaelides M, Benveniste H, Wang GJ, Volkow ND, Thanos P. (2008) The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice. Synapse (May), 62(5): 319-324.
- Thanos PK, Cavigelli SA, Michaelides M, Olvet DM, Patel U, Diep MN, Volkow ND, Thanos P. (2008) A non-invasive method for detecting the metabolic stress response in rodents: characterization and disruption of the circadian corticosterone rhythm. Physiol Res (Apr), 58(2): 219-228.
- Wang GJ, Tomasi D, Backus W, Wang R, Telang F, Geliebter A, Korner J, Bauman A, Fowler JS, Thanos PK, Volkow ND, Thanos P. (2008) Gastric distention activates satiety circuitry in the human brain. Neuroimage (Feb), 39(4): 1824-1831.
- Thanos PK, Michaelides M, Piyis YK, Wang GJ, Volkow ND, Thanos P. (2008) Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo muPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography. Synapse (Jan), 62(1): 50-61.
- Thanos PK, Michaelides M, Benveniste H, Wang GJ, Volkow ND, Thanos P. (2007) Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents. Pharmacol Biochem Behav (Oct), 87(4): 426-433.
- RodrÃguez-Gómez JA, Lu JQ, Velasco I, Rivera S, Zoghbi SS, Liow JS, Musachio JL, Chin FT, Toyama H, Seidel J, Green MV, Thanos PK, Ichise M, Pike VW, Innis RB, McKay RD, Thanos P. (2007) Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease. Stem Cells (Apr), 25(4): 918-928.
- Wang GJ, Yang J, Volkow ND, Telang F, Ma Y, Zhu W, Wong CT, Tomasi D, Thanos PK, Fowler JS. (2006) Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry. Proceedings of the National Academy of Sciences of the United States of America (Oct), 103(42): 15641-5. doi:10.1073/pnas.0601977103
- Volkow ND, Wang GJ, Begleiter H, Porjesz B, Fowler JS, Telang F, Wong C, Ma Y, Logan J, Goldstein R, Alexoff D, Thanos PK. (2006) High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors. Archives of general psychiatry (Sep), 63(9): 999-1008.
- Rice O, Saintvictor S, Michaelides M, Thanos P, Gatley SJ. (2006) MicroPET investigation of chronic long-term neurotoxicity from heavy ion irradiation. AAPS J (Aug), 8(3): 508-514.
- Volkow ND, Wang GJ, Franceschi D, Fowler JS, Thanos PP, Maynard L, Gatley SJ, Wong C, Veech RL, Kunos G, Kai Li T. (2006) Low doses of alcohol substantially decrease glucose metabolism in the human brain. NeuroImage (Jan), 29(1): 295-301.
- Thanos PK, Dimitrakakis ES, Rice O, Gifford A, Volkow ND. (2005) Ethanol self-administration and ethanol conditioned place preference are reduced in mice lacking cannabinoid CB1 receptors. Behavioural brain research (Nov), 164(2): 206-13.
- Heidbreder CA, Gardner EL, Xi ZX, Thanos PK, Mugnaini M, Hagan JJ, Ashby CR. (2005) The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence. Brain research. Brain research reviews (Jul), 49(1): 77-105. doi:10.1016/j.brainresrev.2004.12.033
- Thanos PK, Rivera SN, Weaver K, Grandy DK, Rubinstein M, Umegaki H, Wang GJ, Hitzemann R, Volkow ND. (2005) Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking. Life sciences (May), 77(2): 130-9.
- Thanos PK, Katana JM, Ashby CR, Michaelides M, Gardner EL, Heidbreder CA, Volkow ND. (2005) The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats. Pharmacology, biochemistry, and behavior (May), 81(1): 190-7.
- Ding YS, Gatley SJ, Thanos PK, Shea C, Garza V, Xu Y, Carter P, King P, Warner D, Taintor NB, Park DJ, Pyatt B, Fowler JS, Volkow ND. (2004) Brain kinetics of methylphenidate (Ritalin) enantiomers after oral administration. Synapse (New York, N.Y.) (Sep), 53(3): 168-75.
- Thanos PK, Taintor NB, Rivera SN, Umegaki H, Ikari H, Roth G, Ingram DK, Hitzemann R, Fowler JS, Gatley SJ, Wang GJ, Volkow ND. (2004) DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking. Alcoholism, clinical and experimental research (May), 28(5): 720-8.
- Heidbreder CA, Andreoli M, Marcon C, Thanos PK, Ashby CR, Gardner EL. (2004) Role of dopamine D3 receptors in the addictive properties of ethanol. Drugs of today (Barcelona, Spain : 1998) (Apr), 40(4): 355-65.
- Wang GJ, Volkow ND, Thanos PK, Fowler JS. (2004) Similarity between obesity and drug addiction as assessed by neurofunctional imaging: a concept review. Journal of addictive diseases (Jan), 23(3): 39-53.
- Alexoff DL, Vaska P, Marsteller D, Gerasimov T, Li J, Logan J, Fowler JS, Taintor NB, Thanos PK, Volkow ND, Thanos P. (2003) Reproducibility of 11C-raclopride binding in the rat brain measured with the microPET R4: effects of scatter correction and tracer specific activity. J Nucl Med (May), 44(5): 815-822.
- Hitzemann R, Hitzemann B, Rivera S, Gatley J, Thanos P, Shou LL, Williams RW. (2003) Dopamine D2 receptor binding, Drd2 expression and the number of dopamine neurons in the BXD recombinant inbred series: genetic relationships to alcohol and other drug associated phenotypes. Alcohol Clin Exp Res (Jan), 27(1): 1-11.
- Volkow ND, Wang GJ, Fowler JS, Thanos PP, Logan J, Gatley SJ, Gifford A, Ding YS, Wong C, Pappas N, Thanos P. (2002) Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study. Synapse (Nov), 46(2): 79-82.
- Thanos PK, Taintor NB, Alexoff D, Vaska P, Logan J, Grandy DK, Fang Y, Lee JH, Fowler JS, Volkow ND, Rubinstein M. (2002) In vivo comparative imaging of dopamine D2 knockout and wild-type mice with (11)C-raclopride and microPET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine (Nov), 43(11): 1570-7.
- Thanos PK, Volkow ND, Freimuth P, Umegaki H, Ikari H, Roth G, Ingram DK, Hitzemann R. (2001) Overexpression of dopamine D2 receptors reduces alcohol self-administration. Journal of neurochemistry (Sep), 78(5): 1094-103.
- Thanos PK, Tiangco DA, Terzis JK. (2001) Enhanced reinnervation of the paralyzed orbicularis oculi muscle after insulin-like growth factor-I (IGF-I) delivery to a nerve graft. Journal of reconstructive microsurgery (Jul), 17(5): 357-62.
- Wang GJ, Volkow ND, Franceschi D, Fowler JS, Thanos PK, Scherbaum N, Pappas N, Wong CT, Hitzemann RJ, Felder CA. (2000) Regional brain metabolism during alcohol intoxication. Alcoholism, clinical and experimental research (Jun), 24(6): 822-9.
- Volkow ND, Wang GJ, Fowler JS, Franceschi D, Thanos PK, Wong C, Gatley SJ, Ding YS, Molina P, Schlyer D, Alexoff D, Hitzemann R, Pappas N. (2000) Cocaine abusers show a blunted response to alcohol intoxication in limbic brain regions. Life sciences (Feb), 66(12): PL161-7.
- Thanos PK, Okajima S, Tiangco DA, Terzis JK, Thanos P. (1999) Insulin-like growth factor-I promotes nerve regeneration through a nerve graft in an experimental model of facial paralysis. Restor Neurol Neurosci (Jan), 15(1): 57-71.
- Thanos PK, Okajima S, Terzis JK. (1998) Ultrastructure and cellular biology of nerve regeneration. Journal of reconstructive microsurgery (Aug), 14(6): 423-36.
- Thanos PK, Slotnick BM. (1997) Short-term odor memory: effects of posterior transection of the lateral olfactory tract in the rat. Physiology & behavior (Jun), 61(6): 903-6.
- Terzis JK, Sun DD, Thanos PK. (1997) Historical and basic science review: past, present, and future of nerve repair. Journal of reconstructive microsurgery (Apr), 13(3): 215-25.
- Thanos PK, Terzis JK. (1996) A histomorphometric analysis of the cross-facial nerve graft in the treatment of facial paralysis. Journal of reconstructive microsurgery (Aug), 12(6): 375-82.
- Thanos PK, Terzis JK. (1995) Motor endplate analysis of the denervated and reinnervated orbicularis oculi muscle in the rat. Journal of reconstructive microsurgery (Nov), 11(6): 423-8.
- Thanos PK, Jhamandas K, Beninger RJ. (1992) N-methyl-D-aspartate unilaterally injected into the dorsal striatum of rats produces contralateral circling: antagonism by 2-amino-7-phosphonoheptanoic acid and cis-flupenthixol. Brain research (Aug), 589(1): 55-61.
- Pascau J, Gispert JD, Michaelides M, Thanos PK, Volkow ND, Vaquero JJ, Soto-Montenegro ML, Desco M. (1900) Automated method for small-animal PET image registration with intrinsic validation. Molecular imaging and biology (Jan), 11(2): 107-13. doi:10.1007/s11307-008-0166-z
Professional Memberships:
- International Society of Reward Deficiency; member (2015–2019)
- Research Society on Alcoholism; Member (1999–present)
- Society for Neuroscience; Member (1995–present)
Service Activities:
- Participated in annual conference with presentation and meet with students; Assisted with planning meetings and faculty member of the Ingestive Behavior Center at UB (2022)
- faculty member, will assist with future conference; faculty member of the UB CeCaR. (2022)
- Poster reviewer for annual conference of CSTEP since 2017; Poster Reviewer (2022)
- Assisted with Poster review on research day of CRIA, 2016-2020; Poster reviewer (2022)
- Will review and delegate reviews on papers in the area of psychopharmacology; Section Editor, Current Pharmaceutical Design (2021–2022)
- Reviewer of manuscripts in my area of expertise; member of the Editorial Board Journal of Precision Medicine (2021–2022)
- Section editor for Behavioral Pharmacology in the journal Current Psychopharmacology; Section Editor (2020–2022)
- Admissions; Member (2018–present)
- Curriculum; Coordinator (2017–present)