Analyzes xenobiotics and other metabolites, and supports OSHA-sponsored educational activities.

Provides transgenic approaches for the systematic dissection of the genetic, molecular, cellular and physiological mechanisms underlying complex biological processes.

Offers high-throughput, next-generation sequencing and gene-expression analysis services, including 3’-expression, miRNA, exon and gene arrays.

Carries out Sanger sequencing on a fee-for-service basis on instrumentation that typically provides reads of >600bp.

Allows investigators to analyze the kinetics of protein-protein and protein-ligand interactions.

Supports automated crystallization trials in a 1,536-well format, providing a key step in determining atomic scale molecular structures.

Allows identification of differentially expressed proteins via peptide mass fingerprinting.

Identifies proteins in cell or tissue extracts using several different liquid chromotography/mass spectrometry based approaches.

Provides multiparameter flow cytometry services for clinical diagnosis and follow-up, and to basic and clinical researchers.

Hosts analytical fluorescence-activated flow cytometers/cell sorters (FACS) and a state-of-the art high-speed cell sorter.

Performs all procedures related to tissue preservation and histological analysis, including training on cryostat use and other protocols.

Contains a Zeiss LSM-510 Meta NLO laser scanning confocal microscope attached to a Zeiss-inverted microscope upgraded to multiphoton capability.

Utilizes advanced PET radiopharmaceuticals/tracers and the latest PET/CT imaging technology to explore a wide variety of clinical and research questions.

Provides facilities and technical assistance for processing and analyzing samples using electron microscopy.

Houses a transmission electron microscope as well as light microscopes; consults with investigators and assists with equipment operation.

Helps investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors.

Maintains and banks stem cells, and provides stem cells and training to interested researchers.

Engrafts stem cells into mice and other model systems; quantifies cell engraftment, migration and differentiation, and analyzes the behavior consequences of neural engraftment.

Characterizes and identifies epigenetic and transcription signatures of stem cells and their derived progeny using Next-Gen sequencing.