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Core Facilities

Our school’s shared core instrumentation and transgenic animal facilities support research by UB faculty and investigators at our affiliated institutions. These facilities not only house state-of-the-art equipment but in many cases also provide data analysis, training and grant writing consultation.

Wade Sigurdson and a student researcher at work in the Confocal Microscopy/Cellular Imaging facility.
6/19/14

Contains a Zeiss LSM-510 Meta NLO laser scanning confocal microscope attached to a Zeiss-inverted microscope upgraded to multiphoton capability.

2/12/15

Enables researchers to obtain transmission electron microscope images of materials, polymers and biological samples; consults with investigators and assists with equipment operation.

6/19/14

Hosts analytical fluorescence-activated flow cytometers/cell sorters (FACS) and a state-of-the art high-speed cell sorter.

Small intestine cells.
6/19/14

Performs all procedures related to tissue preservation and histological analysis, including training on cryostat use and other protocols.

2/10/15

Helps investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors.

6/19/14

Equips researchers with a HIPAA-compliant computing environment, healthcare datasets and analytic and security consulting.

2/10/15

Offers powerful, analytical instrumentation used to study macromolecular interactions.

2/10/15

Offers high-throughput, next-generation sequencing and gene-expression analysis services, including 3’-expression, miRNA, exon and gene arrays.

6/19/14

Utilizes advanced PET radiopharmaceuticals/tracers and the latest PET/CT imaging technology to explore a wide variety of clinical and research questions.

2/10/15

Offers instrumentation and the technical expertise required to express and purify milligram quantities of soluble and membrane proteins for biophysical and structural characterization.

2/13/15

Identifies proteins in cell or tissue extracts using several different liquid chromotography/mass spectrometry based approaches.

2/19/15

Supports investigators interested in gene transfer using viral vector technologies.

9/9/14

Maintains and banks stem cells, and provides stem cells and training to interested researchers.

SCEF
6/19/14

Engrafts stem cells into mice and other model systems; quantifies cell engraftment, migration and differentiation, and analyzes the behavior consequences of neural engraftment.

2/5/15

Characterizes and identifies epigenetic and transcription signatures of stem cells and their derived progeny using Next-Gen sequencing.

Bacterial cultures in a petri dish.
6/19/14

Analyzes xenobiotics and other metabolites, and supports OSHA-sponsored educational activities.