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Core Facilities

Our school’s shared core instrumentation and transgenic animal facilities support research by UB faculty and investigators at our affiliated institutions. These facilities not only house state-of-the-art equipment but in many cases also provide data analysis, training and grant writing consultation.

Wade Sigurdson and a student researcher at work in the Confocal Microscopy/Cellular Imaging facility.

Contains a Zeiss LSM-510 Meta NLO laser scanning confocal microscope attached to a Zeiss-inverted microscope upgraded to multiphoton capability.


Enables researchers to obtain transmission electron microscope images of materials, polymers and biological samples; consults with investigators and assists with equipment operation.


Hosts analytical fluorescence-activated flow cytometers/cell sorters (FACS) and a state-of-the art high-speed cell sorter.

Small intestine cells.

Performs all procedures related to tissue preservation and histological analysis, including training on cryostat use and other protocols.


Helps investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors.


Equips researchers with a HIPAA-compliant computing environment, healthcare datasets and analytic and security consulting.


Offers powerful, analytical instrumentation used to study macromolecular interactions.


Offers high-throughput, next-generation sequencing and gene-expression analysis services, including 3’-expression, miRNA, exon and gene arrays.


Utilizes advanced PET radiopharmaceuticals/tracers and the latest PET/CT imaging technology to explore a wide variety of clinical and research questions.


Offers instrumentation and the technical expertise required to express and purify milligram quantities of soluble and membrane proteins for biophysical and structural characterization.


Identifies proteins in cell or tissue extracts using several different liquid chromotography/mass spectrometry based approaches.


Supports investigators interested in gene transfer using viral vector technologies.


Maintains and banks stem cells, and provides stem cells and training to interested researchers.


Engrafts stem cells into mice and other model systems; quantifies cell engraftment, migration and differentiation, and analyzes the behavior consequences of neural engraftment.


Characterizes and identifies epigenetic and transcription signatures of stem cells and their derived progeny using Next-Gen sequencing.

Bacterial cultures in a petri dish.

Analyzes xenobiotics and other metabolites, and supports OSHA-sponsored educational activities.