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Resources for the Research Community

From UB colleagues to local, national and international investigators, we support the entire research community by sharing data, performing specialized analyses and providing access to methods and expertise that bolster basic, clinical and translational studies.

Data Collections

The Gronostajski Lab has established this database as a centralized source of information to examine the structure of the control elements of genes known to be regulated by NFI proteins. It aids in grouping genes by common regulatory elements and finding patterns of structure and function of transcription factors in control elements.

The first of its kind, REDfly is a searchable collection of known Drosophila transcriptional cis-regulatory modules (CRMs) and transcription factor binding sites (TFBSs). REDfly includes all experimentally verified fly regulatory elements along with their DNA sequence, their associated genes and the expression patterns they direct. This internationally recognized resource, developed and maintained by the Halfon lab in conjunction with the Center for Computational Research, is the most comprehensive database of regulatory elements for the higher eukaryotes.

High power photomicrograph of osteoclasts and osteoblasts.

Managed by the Department of Orthopaedics, Tumor Unknown collects diagnostic images and patient descriptions for interesting orthopaedic oncology cases on a quarterly basis. It also features tumor data in spreadsheet form and articles on bone tumors.

Services and Facilities

This quantitative imaging research center conducts specialized neuroimaging studies in global and regional brain atrophy in multiple sclerosis and other neurodegenerative disorders, as well as many other quantitative MRI studies, cerebrospinal fluid imaging and optic nerve imaging.

3/2/15

The Clinical Research Office (CRO) supports investigators and study staff by providing the resources and assistance necessary to conduct research in a regulatory compliant manner.

One of the school’s Core Facilities, this laboratory offers academic and industrial investigators access to microscopy, flow cytometry, molecular imaging and real-time and quantitative PCR instrumentation for a nominal fee. Investigators may make reservations online with Calcium login credentials.

Hauptman-Woodward Institute’s high-throughput screening laboratory prepares crystal-growth screening experiments for a nominal fee, which can be waived for academic users under certain circumstances. Investigators are encouraged to contribute their data to the crystallization database being compiled as part of ongoing research in crystal growth at HWI.

Gross Anatomy Lab

The lab permits researchers and students to work with their cadaveric material for surgical training, and learning and reviewing human anatomy. It also loans models to educators, legal professionals and others for demonstrations.

ResearchMatch is a national database that allows researchers to easily and quickly recruit the number and type of human volunteers needed for clinical trials and research studies. The free, secure registry is open to individuals with specific diseases as well as healthy volunteers. A detailed search can yield a pool of potential volunteers who meet all study criteria. The service also may be used to almost instantly test the feasibility of a study idea at no cost.

Toshiba Stroke Research Center

Basic scientists and specialists with diverse clinical interests contribute to the advancement of knowledge in stroke prevention and treatment. Researchers can use the center’s scanning facilities through arrangement with the laboratory director.

Toxicology Research Center

This multidisciplinary center conducts antimicrobial testing as well as studies on biodegradation and preclinical testing in support of new drug applications, particularly grain imaging agents. In addition to its ongoing research projects, the center’s equipment and expertise support university and industrial interests.

Software

ArchAlign identifies shared chromatin structural patterns from high-resolution datasets derived from next-generation sequencing or tiled microarray approaches, by aligning chromatin signals for regions of interest. The Buck Lab makes ArchAlign freely available for academic use.

The Hauptman-Woodward Institute/UB Department of Structural Biology makes its crystallography analysis software available for download by the scientific community.

The Qub suite of programs, developed by the Auerbach lab, aids Markov analysis of single channel records, with applications in neurophysiology, electrophysiology, biophysics and more.

Software developed by Uniform Data System for Medical Rehabilitation provides established means for collecting patient data, enabling providers to evaluate the effectiveness of their programs, establish short- and long-term goals for treatment, coordinate care with resources and much more. In addition to developing these programs, UDS conducts training, consultation and research related to functional assessment in medical rehabilitation.

Supplies for Sale

This center develops and commercializes innovative products and manufactures high quality research reagents for life science and translational research. Reagents are available for a variety of purposes, including cell analysis, DNA/RNA purification, metabolite assays and more.

This arm of the Department of Nuclear Medicine prepares 20 radiopharmaceuticals, including cyclotron-produced positron emission tomography (PET) agents. It also distributes 10 others, purchased in bulk and repackaged for clinical distribution. It serves more than 30 clinical sites with radiopharmaceuticals and provides them with calibration resources and accessories.

Frederick Sachs, PhD, founded this startup to develop treatments for muscular dystrophy based on a peptide derived from tarantula venom. Researchers may purchase the peptide, GsMtx-4, by contacting Sachs.

6/19/14
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