Research Centers

The school’s associated research centers include:

Alzheimer’s Disease Translational Genomics Research Laboratory

Director: Kinga Szigeti, MD, PhD

Conducts research focused on characterizing the contribution of copy number variations to the genetic architecture of Alzheimer’s disease to develop genetic biomarkers for risk stratification; explores olfactory identification deficit as a biomarker of the disease; and uses stem cell technology to study the disease mechanism.


Director: Robert Zivadinov, MD, PhD

Works to extend the boundaries of knowledge about neurological diseases and disorders through innovative neuroimaging research techniques and the application of bioinformatics resources.


Director: Adnan Siddiqui, MD, PhD

Focuses on image optimization and dose reduction, device development and hemodynamics in order to better understand the physiological mechanisms that produce brain aneurysms.


Director: Matthew D. Jones, PhD

A state-of-the-art supercomputing facility with high-end visualization laboratories. Provides consulting services including bioinformatics support, scientific and medical visualization, advanced database design and data mining, parallel computing and software engineering.


Director: Vasanth Kumar, MD

Conducts translational research to prevent and treat disorders of pulmonary transition such as birth asphyxia, persistent pulmonary hypertension of the newborn (PPHN), transient tachypnea of the newborn (TTN) and respiratory distress syndrome (RDS).


Director: Carl V. Granger, MD

Μaintains the world’s largest database for medical rehabilitation outcomes. Facilities use UDSMR’s measurement system to document patient functionality during medical rehabilitation.


Director: John M. Canty, MD

Conducts translational research in preclinical models of ischemic heart disease and pursues parallel patient-oriented investigation in humans with chronic coronary artery disease.


Medical Director: Michelle Hartley-McAndrew, MD

Research encompasses neurobiology of children with autism spectrum disorders; concurrent seizure disorders; epileptiform abnormalities; etiology; screening and evaluation techniques.


Director: Kenneth E. Leonard, PhD

Contributes to research in three primary areas: etiology, prevention and treatment; social, psychological and neurophysiological aspects of addiction; and health and medical aspects of addiction.


Medical Director: Arie Weinstock, MD

Clinical research and drug trials focus on individuals with difficult-to-control seizures and aim to improve treatment, prevention or diagnosis of seizures and epilepsy.


Directors: Danielle Goetz, MD (pediatric) and Carla A. Frederick, MD (adult)

Has participated in more than 40 clinical trials and has helped bring several drugs through development to clinical use for patients with CF, focusing on inhaled antibiotics, mucoactive drugs and CFTR potentiators and correctors.


Director: Teresa Quattrin, MD

Participates in the T1 Diabetes Exchange research network and registry and conducts translational research into obesity and the prevention and control of Type 1 and 2 diabetes.


Director: Ajay Chaudhuri, MD

Offers care for approximately 16,000 patients a year who have diabetes and other endocrine pathologies, making it the largest academic diabetic unit in New York.


Director: Lawrence Wrabetz, MD

Supports basic and clinical research related to the cause, prevention and treatment of myelin-related diseases, such as Krabbe and other leukodystrophies, multiple sclerosis and hereditary neuropathies.


Director: Steven J. Fliesler, PhD

Nationally innovative collaboration among the UB Department of Ophthalmology, the Elizabeth Pierce Olmsted, MD, Center for the Visually Impaired and University Ophthalmology Services.

Jacobs Multiple Sclerosis Center for Treatment and Research

Director: Bianca Weinstock-Guttman, MD

Conducts research to understand mechanisms of disease progression, with a primary focus on the role of environmental factors and environmental-gene interactions. Also conducts clinical trials for new pharmacologic interventions.

Liver Biorepository at the UB Clinical and Translational Science Institute

Director: Andrew H. Talal, MD

Collects, stores and manages clinically annotated human liver samples for use in clinical and translational research. Offers samples from patients with a full spectrum of liver conditions, including fatty liver disease and hepatitis B and C.


Directors: John M. Canty, Jr., MD and Robert Zivadinov, MD, PhD

Provides cutting edge MRI and PET CT imaging facilities dedicated to advancing technical, basic, and translational research.

Neuromuscular Disease Research Center

Director: Gil I. Wolfe MD, FAAN

Conducts clinical research and clinical trials in a wide variety of neuromuscular disorders with a focus on myasthenia gravis and peripheral neuropathy, including neuropathic pain.


Director: Ralph H. Benedict, PhD

Employs behavioral psychometrics to understand how cerebral disease affects personality, cognition and psychiatric stability. Develops widely adopted tests, notably memory tests, to determine areas of cognitive impairment in multiple sclerosis, cerebral injury and disease, and other conditions.

Patient Safety Research Center

Director: Ranjit Singh, MB BChir, MBA

Works to reduce the national burden of medical errors through educational and research programs using collaborative, multidisciplinary team-based safety measurement and enhancement.


Director: Ranjit Singh, MB BChir, MBA

Transdisciplinary research unit dedicated to improving health, patient care and medical education by encouraging scholarship in primary care.


Director: Paul J. Kostyniak, PhD/Pharmacology and Toxicology

Facilitates research; provides occupational and environmental health and safety training and educational programs; and houses the Atlantic OSHA Training Center.


Director: Timothy F. Murphy, MD

An integrated academic home for UB’s outstanding clinical research and translational science, and the hub of the Buffalo Translational Consortium. The CTSI provides innovative research tools, support, training, resources and coordination.


Executive Director: Norma J. Nowak, PhD

Home to more than 250 scientists and research staff with physical, biological and computational expertise who are engaged in interdisciplinary translational research collaborations.

Upstate New York Practice Based Research Network

Director: Ranjit Singh, MB BChir, MBA (Interim)

Investigates questions related to community-based primary care practice. Aims to improve patient care by translating research into practice and by involving practices in research.


Director: Richard M. Gronostajski, PhD

This NYSTEM-funded Center is dedicated to promoting and supporting stem cell research within UB, Western New York and the world.


Director: Thomas Melendy, PhD

Brings together researchers and their students/fellows interested in understanding the molecular mechanisms of infectious diseases and host defenses against them.