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Robert Zivadinov MD, PhD

Department of Neurology

Professor and Director, Buffalo Neuroimaging Analysis Center

Specialty/Research Focus

Multiple Sclerosis; Neuroimaging

Overview Research Publications Activities

Professional Summary:

Dr. Zivadinov has acquired extensive experience in multiple sclerosis through conducting significant and progressive research, and has published more than 180 papers and 350 abstracts. At present, Dr. Zivadinov is pursuing research studies of quantitative MRI findings and venous function in multiple sclerosis as well as therapeutic interventions, including strategies towards assessing neuroprotective efforts in multiple sclerosis. His current interests also concentrate on genetic and neuroepidemiology fields of the same disease.

Education and Training:

PhD, University of Rijeka (2002)
Residency, University of Trieste (1999)
MD, University of Trieste (1995)
MS, University of Rijeka (1995)
MD, University of Rijeka (1993)

Employment:

Clinical Professor of Neurology, Florida International University College of Medicine (2009-present)
Associate Professor of Neurology, SUNY at Buffalo (2007-present)
Director of Residency Research and Fellowship Training Program, SUNY at Buffalo (2004-present)
Director of Buffalo Neuroimaging Analysis Center, Jacobs Neurological Institute (2003-present)
Multiple Sclerosis Scientific Consultant, National and International pharmaceutical industry and foundations (1999-present)

Awards and Honors:

American Academy of Neurology Fellow (2010)
MS Community Champion Award (2010)
Biography included in the 21st ed. of Century Award for Achievement (2005)
Biography included in the 7th ed. of Marquis Whoâ€™s Who in Science and Eng (2003)
Young Scientific Investigator Travel Award (2002)
Young Scientific Investigator Travel Award (2002)
First place for best Poster in Neuroimmunology (2001)
Young Scientific Investigator Travel Award (2001)
Second place for best Oral Communication (2000)

Grants and Sponsored Research:

September 2010–September 2013
Gene-Environmental Interactions in Progression of Multiple Sclerosis
Department of Defense Multiple Sclerosis Research Program of the Office of the Congressionally Directed Medical Research Program
Role: Co-Investigator
February 2009–June 2013
Evolution of gray matter (GM) atrophy over 4 years in observational study of early interferon (IFN)Î²-1a intramuscular (I.M.) (AvonexÂ® ) treatment in high risk subjects after clinically isolated syndrome (SET substudy)
Biogen Idec, Inc.
Role: Principal Investigator
December 2009–December 2012
A multinational, multicenter, randomized, parallel-group study performed in subjects with Relapsing-Remitting Multiple Sclerosis (RRMS) to assess the efficacy, safety and tolerability of Glatiramer Acetate (GA) injection 40 mg/ml administered three times
Teva Pharmacuticals, Inc.
Role: Principal Investigator
September 2009–December 2012
A twenty-four week, two arm, pilot trial to evaluate remyelination/demyelination, gray matter volume and iron deposition in the central nervous system (CNS) and immune status of subjects with relapsing-remitting multiple sclerosis (RRMS) treated with Reb
EMD Serono Inc.
Role: Principal Investigator
October 2008–September 2012
Longitudinal analysis of regional brain atrophy and personality change in MS
National Multiple Sclerosis Society
Role: Co-Investigator
January 2011–December 2011
Neurology Lecture Series
Teva Neuroscience, Inc.
Role: Principal Investigator
January 2011–December 2011
Interactive web-based continuing medical education (CME) program: Managing Parkinsonâ€˜s Disease: Diagnosis and Treatment Problems and Solutions
Biogen Idec, Inc.
Role: Principal Investigator
October 2010–December 2011
Interactive web-based continuing medical education (CME) program: Understanding Multiple Sclerosis: Advances in Epidemiology, Pathology, Imaging and Treatment Strategies
Teva Neuroscience, Inc.
Role: Principal Investigator
January 2010–December 2011
Magnetic resonance imaging (MRI testing of active implantable medical devices (AIMDs)
Greatbatch Medical
Role: Principal Investigator
December 2009–December 2011
Natalizumab Temporary Discontinuation Study (NaTDS)
Biogen Idec, Inc.
Role: Principal Investigator
December 2009–December 2011
Combined transcranial and extracranial venous Doppler evaluation (CTEVD study). Description of the design and interim results of an epidemiological study of the prevalence of chronic cerebrospinal venous insufficiency in MS and related diseases
Direct MS Foundation, Jacquemin Foundation, Bronfman Foundation
Role: Principal Investigator
December 2009–December 2011
PREMiSe Trial: Prospective Randomized Endovascular therapy in Multiple Sclerosis
Direct MS Foundation
Role: Co-Principal Investigator
October 2008–December 2011
BDNF in multiple sclerosis (Renewal).
National Multiple Sclerosis Society
Role: Co-Investigator

See All (13 Total) >

Evaluative Studies and Case Reports:

Hoque R, Ledbetter C, Gonzalez-Toledo E, Misra V, Menon U, Kenner M, Rabinstein AA, Kelley RE, Zivadinov R, Minagar A. The role of quantitative neuroimaging indices in the differentiation of ischemia from demyelination: an analytical study with case presentation. Int Rev Neurobiol. 2007; 79.
Moretti R, Bava A, Torre P, Antonello RM, Zorzon M, Zivadinov R, Cazzato G. Bilingual aphasia and subcortical-cortical lesions. Percept Mot Skills. 2001; 92(3 Pt).

Journal Articles:

Zivadinov R, Heininen-Brown M, Schirda CV, Poloni GU, Bergsland N, Magnano CR, Durfee J, Kennedy C, Carl E, Hagemeier J, Benedict RH, Weinstock-Guttman B, Dwyer MG. Abnormal subcortical deep-gray matter susceptibility-weighted imaging filtered phase measurements in patients with multiple sclerosis: a case-control study. Neuroimage. 2012; 59(1).
Weinstock-Guttman B, Zivadinov R, Ramanathan M. Inter-dependence of vitamin D levels with serum lipid profiles in multiple sclerosis. J Neurol Sci. 2011; 311(1-2).
Polak P, Magnano C, Zivadinov R, Poloni G. 3D FLAIRED: 3D fluid attenuated inversion recovery for enhanced detection of lesions in multiple sclerosis. Magn Reson Med. 2011.
Covey TJ, Zivadinov R, Shucard JL, Shucard DW. Information processing speed, neural efficiency, and working memory performance in multiple sclerosis: Differential relationships with structural magnetic resonance imaging. J Clin Exp Neuropsychol. 2011; 33(10).
Dolic K, Weinstock-Guttman B, Marr K, Valnarov V, Carl E, Hagemeier J, Brooks C, Kilanowski C, Hojnacki D, Ramanathan M, Zivadinov R. Risk Factors for Chronic Cerebrospinal Venous Insufficiency (CCSVI) in a Large Cohort of Volunteers. PLoS One. 2011; 6(11).
Habib CA, Liu M, Bawany N, Garbern J, Krumbein I, Mentzel HJ, Reichenbach J, Magnano C, Zivadinov R, Haacke EM. Assessing Abnormal Iron Content in the Deep Gray Matter of Patients with Multiple Sclerosis versus Healthy Controls. AJNR Am J Neuroradiol. 2011.
Zivadinov R, Poloni GU, Marr K, Schirda CV, Magnano CR, Carl E, Bergsland N, Hojnacki D, Kennedy C, Beggs CB, Dwyer MG, Weinstock-Guttman B. Decreased brain venous vasculature visibility on susceptibility-weighted imaging venography in patients with multiple sclerosis is related to chronic cerebrospinal venous insufficiency. BMC Neurol. 2011; 11.
Weinstock-Guttman B, Zivadinov R, Mahfooz N, Carl E, Drake A, Schneider J, Teter B, Hussein S, Mehta B, Weiskopf M, Durfee J, Bergsland N, Ramanathan M. Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis. J Neuroinflammation. 2011; 8.
O'Connor K, Weinstock-Guttman B, Carl E, Kilanowski C, Zivadinov R, Ramanathan M. Patterns of dietary and herbal supplement use by multiple sclerosis patients. J Neurol. 2011.
Zivadinov R, Ramanathan M, Dolic K, Marr K, Karmon Y, Siddiqui AH, Benedict RH, Weinstock-Guttman B. Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives. Expert Rev Neurother. 2011; 11(9).
Zamboni P, Galeotti R, Weinstock-Guttman B, Kennedy C, Salvi F, Zivadinov R. Venous Angioplasty in Patients with Multiple Sclerosis: Results of a Pilot Study. Eur J Vasc Endovasc Surg. 2011.
Antulov R, Carone DA, Bruce J, Yella V, Dwyer MG, Tjoa CW, Benedict RH, Zivadinov R. Regionally distinct white matter lesions do not contribute to regional gray matter atrophy in patients with multiple sclerosis. J Neuroimaging. 2011; 21(3).
Batista S, Zivadinov R, Hoogs M, Bergsland N, Heininen-Brown M, Dwyer MG, Weinstock-Guttman B, Benedict RH. Basal ganglia, thalamus and neocortical atrophy predicting slowed cognitive processing in multiple sclerosis. J Neurol. 2011.
Poloni G, Minagar A, Haacke EM, Zivadinov R. Recent developments in imaging of multiple sclerosis. Neurologist. 2011; 17(4).
Mokin M, Kass-Hout T, Kass-Hout O, Zivadinov R, Mehta B. Blood Pressure Management and Evolution of Thrombolysis-associated Intracerebral Hemorrhage in Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2011.
Benedict RH, Zivadinov R. Risk factors for and management of cognitive dysfunction in multiple sclerosis. Nat Rev Neurol. 2011; 7(6).
Dalaker TO, Zivadinov R, Ramasamy DP, Beyer MK, Alves G, Bronnick KS, Tysnes OB, Aarsland D, Larsen JP. Ventricular enlargement and mild cognitive impairment in early Parkinson's disease. Mov Disord. 2011; 26(2).
Alexander JS, Zivadinov R, Maghzi AH, Ganta VC, Harris MK, Minagar A. Multiple sclerosis and cerebral endothelial dysfunction: Mechanisms. Pathophysiology. 2011; 18(1).
Dalaker TO, Zivadinov R, Ramasamy DP, Beyer MK, Alves G, Bronnick KS, Tysnes OB, Aarsland D, Larsen JP. Ventricular enlargement and mild cognitive impairment in early Parkinson's disease. Mov Disord. 2010.
Dalaker TO, Zivadinov R, Larsen JP, Beyer MK, Cox JL, Alves G, Bronnick K, Tysnes OB, Antulov R, Dwyer MG, Aarsland D. Gray matter correlations of cognition in incident Parkinson's disease. Mov Disord. 2010; 25(5).
Antulov R, Carone DA, Bruce J, Yella V, Dwyer MG, Tjoa CW, Benedict RH, Zivadinov R. Regionally Distinct White Matter Lesions Do Not Contribute to Regional Gray Matter Atrophy in Patients with Multiple Sclerosis. J Neuroimaging. 2010.
Minagar A, Alexander JS, Sahraian MA, Zivadinov R. Alemtuzumab and multiple sclerosis: therapeutic application. Expert Opin Biol Ther. 2010; 10(3).
Horstman LL, Jy W, Ahn YS, Zivadinov R, Maghzi AH, Etemadifar M, Steven Alexander J, Minagar A. Role of platelets in neuroinflammation: a wide-angle perspective. J Neuroinflammation. 2010; 7.
Horáková D, Kýr M, Havrdová E, Doležal O, Lelková P, Pospíšilová L, Bergsland N, Dwyer MG, Cox JL, Hussein S, Seidl Z, Vanecková M, Krásenský J, Zivadinov R. Apolipoprotein E e4-Positive multiple sclerosis patients develop more gray-matter and whole-brain atrophy: a 15-year disease history model based on a 4-year longitudinal study. Folia Biol (Praha). 2010; 56(6).
Dalaker TO, Larsen JP, Dwyer MG, Aarsland D, Beyer MK, Alves G, Bronnick K, Tysnes OB, Zivadinov R. White matter hyperintensities do not impact cognitive function in patients with newly diagnosed Parkinson's disease. Neuroimage. 2009; 47(4).
Havrdova E, Zivadinov R, Krasensky J, Dwyer MG, Novakova I, Dolezal O, Ticha V, Dusek L, Houzvickova E, Cox JL, Bergsland N, Hussein S, Svobodnik A, Seidl Z, Vaneckova M, Horakova D. Randomized study of interferon beta-1a, low-dose azathioprine, and low-dose corticosteroids in multiple sclerosis. Mult Scler. 2009; 15(8).
Frohman EM, Dwyer MG, Frohman T, Cox JL, Salter A, Greenberg BM, Hussein S, Conger A, Calabresi P, Balcer LJ, Zivadinov R. Relationship of optic nerve and brain conventional and non-conventional MRI measures and retinal nerve fiber layer thickness, as assessed by OCT and GDx: a pilot study. J Neurol Sci. 2009; 282(1-2).
Geurts JJ, Stys PK, Minagar A, Amor S, Zivadinov R. Gray matter pathology in (chronic) MS: modern views on an early observation. J Neurol Sci. 2009; 282(1-2).
Horakova D, Dwyer MG, Havrdova E, Cox JL, Dolezal O, Bergsland N, Rimes B, Seidl Z, Vaneckova M, Zivadinov R. Gray matter atrophy and disability progression in patients with early relapsing-remitting multiple sclerosis: a 5-year longitudinal study. J Neurol Sci. 2009; 282(1-2).
Schwendimann RN, Harris MK, Elliott DG, Menon U, Gonzalez-Toledo E, Zivadinov R, Pressly TA, Kelley RE, Hoque R, Fowler M, Maghzi AH, Etemadifar M, Saadatnia M, Minagar A. Neurosarcoidosis: Clinical Features, Diagnosis, and Management. Am J Ther. 2009.
Salter AR, Conger A, Frohman TC, Zivadinov R, Eggenberger E, Calabresi P, Cutter G, Balcer L, Frohman EM. Retinal architecture predicts pupillary reflex metrics in MS. Mult Scler. 2009; 15(4).
Horstman LL, Jy W, Bidot CJ, Ahn YS, Kelley RE, Zivadinov R, Maghzi AH, Etemadifar M, Mousavi SA, Minagar A. Antiphospholipid antibodies: paradigm in transition. J Neuroinflammation. 2009; 6.
Di Perri C, Dalaker TO, Beyer MK, Zivadinov R. Neuroimaging of cognitive impairments in vascular disease. Int Rev Neurobiol. 2009; 84.
Zivadinov R. Advanced magnetic resonance imaging metrics: implications for multiple sclerosis clinical trials. Methods Find Exp Clin Pharmacol. 2009; 31(1).
Dwyer MG, Bergsland N, Saluste E, Sharma J, Jaisani Z, Durfee J, Abdelrahman N, Minagar A, Hoque R, Munschauer FE, Zivadinov R. Application of hidden Markov random field approach for quantification of perfusion/diffusion mismatch in acute ischemic stroke. Neurol Res. 2008; 30(8).
Zivadinov R, Bergsland N, Stosic M, Sharma J, Nussenbaum F, Durfee J, Hani N, Abdelrahman N, Jaisani Z, Minagar A, Hoque R, Munschauer FE, Dwyer MG. Use of perfusion- and diffusion-weighted imaging in differential diagnosis of acute and chronic ischemic stroke and multiple sclerosis. Neurol Res. 2008; 30(8).
Zivadinov R, Reder AT, Filippi M, Minagar A, Stüve O, Lassmann H, Racke MK, Dwyer MG, Frohman EM, Khan O. Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis. Neurology. 2008; 71(2).
Zivadinov R, Stosic M, Cox JL, Ramasamy DP, Dwyer MG. The place of conventional MRI and newly emerging MRI techniques in monitoring different aspects of treatment outcome. J Neurol. 2008; 255 S.
Frohman EM, Costello F, Stüve O, Calabresi P, Miller DH, Hickman SJ, Sergott R, Conger A, Salter A, Krumwiede KH, Frohman TC, Balcer L, Zivadinov R. Modeling axonal degeneration within the anterior visual system: implications for demonstrating neuroprotection in multiple sclerosis. Arch Neurol. 2008; 65(1).
Stüve O, Bennett JL, Hemmer B, Wiendl H, Racke MK, Bar-Or A, Hu W, Zivadinov R, Weber MS, Zamvil SS, Pacheco MF, Menge T, Hartung HP, Kieseier BC, Frohman EM. Pharmacological treatment of early multiple sclerosis. Drugs. 2008; 68(1).
Brass SD, Zivadinov R, Bakshi R. Acute demyelinating optic neuritis: a review. Front Biosci. 2008; 13.
Shah A, Eggenberger E, Zivadinov R, Stüve O, Frohman EM. Corticosteroids for multiple sclerosis: II. Application for disease-modifying effects. Neurotherapeutics. 2007; 4(4).
Frohman EM, Shah A, Eggenberger E, Metz L, Zivadinov R, Stüve O. Corticosteroids for multiple sclerosis: I. Application for treating exacerbations. Neurotherapeutics. 2007; 4(4).
Zivadinov R. Can imaging techniques measure neuroprotection and remyelination in multiple sclerosis? Neurology. 2007; 68(22 Su).
Zivadinov R, Uxa L, Bratina A, Bosco A, Srinivasaraghavan B, Minagar A, Ukmar M, Benedetto S, Zorzon M. HLA-DRB1*1501, -DQB1*0301, -DQB1*0302, -DQB1*0602, and -DQB1*0603 alleles are associated with more severe disease outcome on MRI in patients with multiple sclerosis. Int Rev Neurobiol. 2007; 79.
Dolezal O, Dwyer MG, Horakova D, Havrdova E, Minagar A, Balachandran S, Bergsland N, Seidl Z, Vaneckova M, Fritz D, Krasensky J, Zivadinov R. Detection of cortical lesions is dependent on choice of slice thickness in patients with multiple sclerosis. Int Rev Neurobiol. 2007; 79.
Zivadinov R, Cox JL. Neuroimaging in multiple sclerosis. Int Rev Neurobiol. 2007; 79.
Sharma J, Zivadinov R, Jaisani Z, Fabiano AJ, Singh B, Horsfield MA, Bakshi R. A magnetization transfer MRI study of deep gray matter involvement in multiple sclerosis. J Neuroimaging. 2006; 16(4).
Frohman E, Costello F, Zivadinov R, Stuve O, Conger A, Winslow H, Trip A, Frohman T, Balcer L. Optical coherence tomography in multiple sclerosis. Lancet Neurol. 2006; 5(10).
Frohman EM, Stüve O, Havrdova E, Corboy J, Achiron A, Zivadinov R, Sorensen PS, Phillips JT, Weinshenker B, Hawker K, Hartung HP, Steinman L, Zamvil S, Cree BA, Hauser S, Weiner H, Racke MK, Filippi M. Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectations. Arch Neurol. 2005; 62(10).
Zorzon M, Zivadinov R, Locatelli L, Giuntini D, Toncic M, Bosco A, Nasuelli D, Bratina A, Tommasi MA, Rudick RA, Cazzato G. Long-term effects of intravenous high dose methylprednisolone pulses on bone mineral density in patients with multiple sclerosis. Eur J Neurol. 2005; 12(7).
Zivadinov R. Steroids and brain atrophy in multiple sclerosis. J Neurol Sci. 2005; 233(1-2).
Zivadinov R, Leist TP. Clinical-magnetic resonance imaging correlations in multiple sclerosis. J Neuroimaging. 2005; 15(4 Sup).
Zivadinov R, Grop A, Sharma J, Bratina A, Tjoa CW, Dwyer M, Zorzon M. Reproducibility and accuracy of quantitative magnetic resonance imaging techniques of whole-brain atrophy measurement in multiple sclerosis. J Neuroimaging. 2005; 15(1).
Locatelli L, Zivadinov R, Grop A, Zorzon M. Frontal parenchymal atrophy measures in multiple sclerosis. Mult Scler. 2004; 10(5).
Bagnato F, Zivadinov R, Cecchinelli D, Tancredi A, Grop A, Pierallini A, De Lena C, Prencipe M, Reale G, Zorzon M, Millefiorini E. beta2-microglobulin serum level is not a marker of disease activity in multiple sclerosis. Eur J Neurol. 2004; 11(7).
Zivadinov R, Bakshi R. Central nervous system atrophy and clinical status in multiple sclerosis. J Neuroimaging. 2004; 14(3 Sup).
Fiotti N, Zivadinov R, Altamura N, Nasuelli D, Bratina A, Tommasi MA, Bosco A, Locatelli L, Grop A, Cazzato G, Guarnieri G, Giansante C, Zorzon M. MMP-9 microsatellite polymorphism and multiple sclerosis. J Neuroimmunol. 2004; 152(1-2).
Zivadinov R, Bakshi R. Role of MRI in multiple sclerosis I: inflammation and lesions. Front Biosci. 2004; 9.
Zivadinov R, Bakshi R. Role of MRI in multiple sclerosis II: brain and spinal cord atrophy. Front Biosci. 2004; 9.
Zivadinov R, Zorzon M, Tommasi MA, Nasuelli D, Bernardi M, Monti-Bragadin L, Cazzato G. A longitudinal study of quality of life and side effects in patients with multiple sclerosis treated with interferon beta-1a. J Neurol Sci. 2003; 216(1).
Zivadinov R, Locatelli L, Stival B, Bratina A, Grop A, Nasuelli D, Brnabic-Razmilic O, Zorzon M. Normalized regional brain atrophy measurements in multiple sclerosis. Neuroradiology. 2003; 45(11).
Zivadinov R, Willheim K, Sepic-Grahovac D, Jurjevic A, Bucuk M, Brnabic-Razmilic O, Relja G, Zorzon M. Migraine and tension-type headache in Croatia: a population-based survey of precipitating factors. Cephalalgia. 2003; 23(5).
Zorzon M, Zivadinov R, Locatelli L, Stival B, Nasuelli D, Bratina A, Bosco A, Tommasi MA, Pozzi Mucelli RS, Ukmar M, Cazzato G. Correlation of sexual dysfunction and brain magnetic resonance imaging in multiple sclerosis. Mult Scler. 2003; 9(1).
Zivadinov R, Iona L, Monti-Bragadin L, Bosco A, Jurjevic A, Taus C, Cazzato G, Zorzon M. The use of standardized incidence and prevalence rates in epidemiological studies on multiple sclerosis. A meta-analysis study. Neuroepidemiology. 2003; 22(1).
Zivadinov R, Zorzon M. Is gadolinium enhancement predictive of the development of brain atrophy in multiple sclerosis? A review of the literature. J Neuroimaging. 2002; 12(4).
Zorzon M, Zivadinov R, Nasuelli D, Ukmar M, Bratina A, Tommasi MA, Mucelli RP, Brnabic-Razmilic O, Grop A, Bonfigli L, Cazzato G. Depressive symptoms and MRI changes in multiple sclerosis. Eur J Neurol. 2002; 9(5).
Zorzon M, Capus L, Pellegrino A, Cazzato G, Zivadinov R. Familial and environmental risk factors in Parkinson's disease: a case-control study in north-east Italy. Acta Neurol Scand. 2002; 105(2).
Zivadinov R, Willheim K, Jurjevic A, Sepic-Grahovac D, Bucuk M, Zorzon M. Prevalence of migraine in Croatia: a population-based survey. Headache. 2001; 41(8).
Zorzon M, Zivadinov R, Monti Bragadin L, Moretti R, De Masi R, Nasuelli D, Cazzato G. Sexual dysfunction in multiple sclerosis: a 2-year follow-up study. J Neurol Sci. 2001; 187(1-2).
Zivadinov R, Sepcic J, Nasuelli D, De Masi R, Bragadin LM, Tommasi MA, Zambito-Marsala S, Moretti R, Bratina A, Ukmar M, Pozzi-Mucelli RS, Grop A, Cazzato G, Zorzon M. A longitudinal study of brain atrophy and cognitive disturbances in the early phase of relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry. 2001; 70(6).
Zorzon M, de Masi R, Nasuelli D, Ukmar M, Mucelli RP, Cazzato G, Bratina A, Zivadinov R. Depression and anxiety in multiple sclerosis. A clinical and MRI study in 95 subjects. J Neurol. 2001; 248(5).
Zivadinov R, De Masi R, Nasuelli D, Bragadin LM, Ukmar M, Pozzi-Mucelli RS, Grop A, Cazzato G, Zorzon M. MRI techniques and cognitive impairment in the early phase of relapsing-remitting multiple sclerosis. Neuroradiology. 2001; 43(4).
Zorzon M, Ukmar M, Bragadin LM, Zanier F, Antonello RM, Cazzato G, Zivadinov R. Olfactory dysfunction and extent of white matter abnormalities in multiple sclerosis: a clinical and MR study. Mult Scler. 2000; 6(6).
Zivadinov R, Zorzon M, Monti Bragadin L, Pagliaro G, Cazzato G. Olfactory loss in multiple sclerosis. J Neurol Sci. 1999; 168(2).
Zivadinov R, Jurjevic A, Willheim K, Cazzato G, Zorzon M. Incidence and prevalence of myasthenia gravis in the county of the coast and Gorski kotar, Croatia, 1976 through 1996. Neuroepidemiology. 1998; 17(5).

See All (76 Total) >

Professional Memberships:

International Society for Neurovascular Diseases (2011)
International Society for Magnetic Resonance Imaging (2005)
European Neurological Society (2004)
Italian Neurological Society (2004)
American Academy of Neurology (2003)
American Society of Neuroimaging (2003)
Croatian Society of Neurology (2001)
Italian Neurological Society of Triveneto (1997)

Presentations:

"Hot topics in MS: Disease fundamentals and management of benefits and risks" The 5th Teva MS Experts Board Meeting (2010)
"MRI measures in GALA study" GALA study (2010)
"Neurodegeneration and CNS repair in MS: MRI evidence (CME)" Advanced imaging techniques in MS (2010)
"Advanced imaging and chronic cerebrospinal venous insufficiency outcomes in multiple sclerosis" (2010)
"Advanced imaging in MS (CME)" Neurologic-Rhematologic Symposium (2010)
"Chronic cerebrospinal venous insufficiency and MRI outcomes in multiple sclerosis" CCSVI in MS (2010)
"Chronic cerebrospinal venous insufficiency in multiple sclerosis" Intiture College of Neurology (2009)
"DMTs and MRI markers of neurodegeneration and CNS repair" Advanced imaging in MS (2009)
"Advanced Imaging Techniques in Multiple Sclerosis: A Gaze into the Future" (2009)
"The Role of Gray Matter Damage in MS (CME)" Multiple Sclerosis & Parkinson Disease: Recent Developments & New Perspectives (2009)
"Advances in magnetic resonance imaging of multiple sclerosis (CME)" Annual Meeting of American Academy of Neurology, (2009)
"Advances in MS Neuroimaging (CME)" 12th Annual Review of Multiple Sclerosis & Parkinsonâ€™s Disease, (2009)
"The role of gray matter pathology in MS (CME)" MRI and MS: From scientific to clinical routine evidence (2009)
"The role of gray matter pathology in MS (CME)" (2009)
"Gray matters: Impact of disease-modifying therapies and gray matter on the brain in MS patients (CME)" (2009)
"Practical Issues in Multiple Sclerosis: Imaging Concepts in MS (CME)" University of South Florida, Practical Issues in MS, Visiting Professors Series (2009)
"New MRI advances in MS (CME; GR)" , University of Missisipi, Department of Neurology, (2008)
"Using brain imaging to measure potential remyelination processes" The 2nd Teva Myelin Repair Meeting (2008)
"Long term effect of disease modifying therapies â€“ New emerging MRI techniques in monitoring abnormalities and disability in MS" 5th LATAM (Latin America Multiple Sclerosi Meeting), (2008)
"Neuroprotection in MS as evidenced by MRI (CME; GR)" (2008)
"Using brain imaging to measure potential remyelination processes (CME; GR)" (2008)
"Can we measure remyelination with MRI in MS ? (CME; GR)" (2008)
"Advanced Imaging Techniques: New Management Strategies for Multiple Sclerosis and Parkinsonâ€™s Disease (CME)" (2008)
"Advanced MRI techniques in MS (CME; GR)" (2008)
"Demyelination and remyelination as evidenced by MRI in MS (CME; GR)" (2008)
"Update on MRI in MS (CME)" (2008)
"Is MRI a reliable tool for prediction of disability progression in patients with early relapsing-remitting multiple sclerosis?" European Charcot Foundation Symposium, 23rd Congress of the European Committee for Treatment and Research in Multiple Sclerosis, (2007)
"Role of MRI in imaging of myelin" 23rd Congress of the European Committee for Treatment and Research in Multiple Sclerosis, (2007)
"Thle place of conventional MRI and newly emerging MRI techniques in monitoring different aspects of treatment outcomes (CME)" The 6th Teva and Sanofi-Aventis International Symposium on MS, Translating new insights on disease progression into treatment optimization in MS, (2007)
"Evidence for remyelination and regeneration by using MRI techniques in MS (CME; GR)" (2007)
"MRI and differential diagnosis of MS (CME)" (2007)
"Neuroprotection in Multiple Sclerosis: Can We Measure Neuroprotection & Remyelination With Imaging Techniques (CME; GR)" , Department of Neurology, University of Hamilton (2007)
"Role of MRI in MS (CME)" , Department of Neurology, University of Hamilton, (2007)
"Remyelination and neuroprotection as evidenced by MRI (CME)" (2007)
"Evidence for Neuroprotection in Multiple Sclerosis: Can We Measure Neuroprotection & Remyelination With Imaging Techniques (CME; GR)" (2007)
"Inflammation and Neurodegeneration in MS as Evidenced by MRI: Current Knowledge and Future Perspectives (CME)" (2006)
"Application of MRI in making diagnosis and prognosis of MS (CME; GR)" (2006)
"MRI evidence for neuroprotection and remyelination (CME; GR)" (2006)
"Understanding of MS through MRI (CME)" (2006)
"MRI in pediatric MS" National Multiple Sclerosis Society meeting; (2006)
"Improving adherence and treatments outcomes in MS: A multifaceted challenge" Annual Meeting of the Consortium of Multiple Sclerosis Centers, Biogen Idec Inc. (2006)
"Inflammation and neurodegeneration in MS as Evidenced by MRI: Implications for current and future therapies" Annual Meeting of the Consortium of Multiple Sclerosis Centers, Teva Neuroscience Inc. (2006)
"MS management: Using history to guide the future" Annual Meeting of the Consortium of Multiple Sclerosis Centers, Teva Neuroscience Inc. (2006)
"Inflammation and neurodegeneration in MS: Evidence from MRI studies (CME: GR)" (2006)
"Aging with MS and other neurodegenerative diseases (CME; GR)" (2006)
"MRI in MS: Neurodegeneration and neuroprotection (CME; GR)" (2006)
"Multiple Sclerosis: Imuunological, genetic and clinical characteristics (CME; GR)" (2006)
"CNS atrophy in MS" Regional MS meeting: New frontiers in imaging (2006)
"MRI in MS: New MRI and immunological concepts (CME)" (2006)
"Pathogenesis of MS and MRI correlations" (2006)
"Rationale for diagnostic MRI criteria and new imaging techniques" Regional MS meeting: New frontiers in imaging, (2006)
"Role of emerging MRI techniques in MS (CME: GR)" (2006)
"Role of MRI in diagnosis and prognosis of MS: Rationale for early treatment" Regional MS Forum Middle East (2006)
"Inflammation and neurodegeneration as edvidenced by use of MRI (CME)" , University of South Florida, Practical Issues in MS, Visiting Professors Series (2006)
"Corticosteroids in MS" NMSS Task Force meeting on role of steroids in MS (2005)
"MRI in MS: New concepts (CME)" (2005)
"Application of MRI in MS: What we learned in the last decade" National Multiple Sclerosis Society Annual Meeting (2005)
"Corticosteroid therapy in multiple sclerosis" University Classes in Multiple Sclerosis, European Charcot Foundation, (2005)
"Inflammation and neurodegeneration in MS: What lessons we learned in the last decade using MRI (JMC)" (2005)
"Controversis in neuropsychology of multiple sclerosis: Role of structural MRI in detecting cognitive impairment in patients with Multiple Sclerosis" Serono Symposia International (2005)
"Magnetic Resonance Imaging in MS: What we learned in the last decade (CME)" (2005)
"MRI as marker of neurodegeneration in MS (CME; GR)" (2005)
"Neuroimaging in multiple sclerosis: Nonconventinal MRI measure in MS (CME)" (2005)
"The meaning and application of MRI in MS (CME)" (2005)
"Utilizing MRI to diagnose and treat multiple sclerosis (CME; GR)" (2005)
"Evaluation of effect of disease-modifying treatment on conventional and nonconventional MRI measures (CME; GR)" (2005)
"Neurodegeneration and neuroprotection evaluated by different non-conventional MRI measures (JMC)" (2005)
"Pseudoatrophy and irreversible atrophy in MS" (2005)
"Update on MRI in MS: New evidence for neurodegeneration" (2005)
"Use of MRI in multiple sclerosis" National Multiple Sclerosis Society (2005)
"Overview of Buffalo Neuroimaging Analysis Center MRI activities" (2005)
"New advances in managing MS - Magnetic resonance imaging in MS: Neurodegeneration and neuroprotection (CME)" (2005)
"Buffalo Neuroimaging Analysis Center database approach experience. A new model for magnetic resonance imaging and clinical and research studies (CME)" , University of Cincinnati (2004)
"Magnetic resonance imaging in multiple sclerosis. Beyond enhancement and T2 (CME)" Thomas Jefferson University Neurology Resident CME Conference, (2004)
"Identifying disease modifying genes in multiple sclerosis. Clinical and MRI correlations" , Harvard Medical School (2004)
"Application of MRI in multiple sclerosis and Assessment of treatment effect (CME)" (2004)
"Application of the non-conventional MRI in the sudy of MS" (2004)
"Long-term efficacy outcomes of diseasemodifying therapy in multiple sclerosis" Dompeâ€™ Biotec Symposium 35th Congress of Italian Neurol. Society (2004)
"Steroid therapy and multiple sclerosis" , Harvard Medical School (2004)
"Application of global and regional MRI measures in the study of multiple sclerosis" (2004)
"Dompeâ€™ Biotec Symposium 35th Congress of Italian Neurol. Society" , Dept of Neurology, McGill University; (2004)
"Global and regional MRI measures in the study of multiple sclerosis" , Dept of Neurology, University of British Columbia; (2004)
"Application of Quantitative MRI in diagnosis and prognosis of multiple sclerosis (CME; GR)" (2004)
"Application of Quantitative MRI in diagnosis and prognosis of multiple sclerosis- Assessment of treatment effect (CME)" , Department of Clinical Neurological Sciences, University of Western Ontario (2004)
"Effect of intravenous methyl-prednisolone on brain atrophy and confluent T2 lesions in relapsing-remitting multiple sclerosis" 9th European Charcot Foundation, (2003)
"Longitudinal study of MRI" 34th Congress of Italian Neurol. Society (2003)
"The evaluation of disease course by means of MRI" Scientific meeting on Multiple Sclerosis (2003)
"Brain and spinal cord atrophy in multiple sclerosis" 26th Annual Meeting, American Society of Neuroimaging, New Orleans, (2003)
"MRI in MS: Use of new neuroimaging techniques in diagnosis, prognosis and in evaluation of the disease-modifying treatments efficacy" , Farmades Meeting (2002)
"New Diagnostic Criteria for Multiple Sclerosis" 3rd Croatian Congress of Neurology, (2001)
"Managing the Adverse Effects in Multiple Sclerosis patients during Interferon beta-1b therapy" , Farmades Meeting (2001)
"Quality of Life in Multiple Sclerosis Patients During Interferon beta-1b therapy" Farmades Meeting (2001)
"A longitudinal study of brain atrophy and cognitive disturbances in early phase of relapsing-remitting multiple sclerosis" International Symposium on Multiple Sclerosis, (2000)
"Brain and spinal cord atrophy in multiple sclerosis: the new measures in clinical trials" Annual scientific meeting of Slovenian neurologists (2000)
"The use of NMR in diagnosing MS" European Medical Studentâ€™s Association (EMSA), 4th Croatian International Scientific Symposium, (2000)
"Cerebral atrophy in multiple sclerosis: a new neuroradiological endpoint" Conference on MRI techniques in Multiple Sclerosis (1999)
"Incidence and prevalence of Myasthenia Gravis in the County of the Coast and Gorski Kotar, Croatia, 1976 through 1996" Annual scientific conference of the University of Rijeka, Croatia (1998)
"Assessing inflammation and neurodegeneration with MRI measures: Lessons from Multiple Sclerosis (JMC)"
"Can Imaging Techniques Measure Remyelination & Neuroprotection in MS ? (CME; GR)"
"Can we measure neuroprotection & remyelination with imaging techniques in multiple sclerosis (CME; GR)"
"MR non-conventional techniques and clinical correlates in MS (CME, GR)"

See All (101 Total) >

Service Activities:

Austrian Science Foundation; Grant Reviews; Reviewer (2010)
BMC Neurol - Section Editor for demyelinating diseases; Editorial Director (2010)
Medical Research Council; Grant Reviews; Reviewer (2010)
President Elect - International Society for Neurovascular Diseases; President (2010)
CTRC Imaging Committee; Committee Member (2009)
CTRC Translational Technologies and Resources Committee; Committee Member (2009)
Neuroradiology; Genome Medicine; International Journal of MS Care; Journal of Cerebral Blood Flow; Magnetic Resonance in Medicine; Reviewer (2009)
Search Committee for Center for Brain and Behavior Informatics; Committee Member (2009)
Acta Neurologica Scandinavica; Human Brain Mapping; Journal of Neuroimflammation; Image and Vision Computing; CNS Spectrum; Journal Reviews; Reviewer (2008)
Fondazione Italiana Sclerosi Multipla; Grant Reviews; Reviewer (2008)
Sheffield Hospitals Charitable Trust; Grant Reviews; Reviewer (2008)
American Academy of Neurology; Abstracts Review; Reviewer (2007)
Expert Opinion in Neurology; Journal of Neuroinflammation; Future Medicine; Journal Reviews; Reviewer (2007)
Human Brain Mapping; Abstract Reviews; Reviewer (2007)
International Society for Magnetic Resonance Imaging; Abstract Reviews; Reviewer (2007)
Multiple Sclerosis Scientific Research Foundation; Grant Reviews; Reviewer (2007)
New England Journal of Medicine; Journal of Pharmacy and Pharmacology; Journal of Interferon & Cytokine Research; BMC Neurology; Journal Reviews; Reviewer (2007)
Wellcome Trust; Grant Reviews; Reviewer (2007)
Multiple Sclerosis; Journal Reviews; Reviewer (2006)
National Multiple Sclerosis Society; Grant Reviews; Reviewer (2006)
American Journal of Neuroradiology; Saudi Medical Journal, Medical Science Monitor; European Journal of Neurology; Neurology India; Journal Reviews; Reviewer (2005)
Resident Advisory Committee; Committee Member (2005)
Director of Resident Research Training SUNY at Buffalo, School of Medicine and Biomedical Sciences Department of Neurology/JNI; Director (2004)
Faculty Council; Councilor (2004)
Radiology; Journal of Neurological Sciences; Journal of Psychosomatic Research; Neuroimage; Brain; Archives of Neurology; Journal Reviews; Reviewer (2004)
NeuroRX; Lancet Neurology; Annals of Neurology; Neurology; Journal of Neurology, Neurosurgery, Psychiatry; Journal Reviews; Reviewer (2003)
Journal of Neuroimaging; Journal of American Medical Association; Drugs; Journal Reviews; Reviewer (2001)
Jog for Jake Committee; Jacobs Neurological Institute; Committee Member

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Buffalo Neuroimaging Analysis Center
E-2 Buffalo General Hospital
100 High St
Buffalo, NY 14203
Phone: (716) 859-7040
Fax: (716) 859-7066
Email: rz4@buffalo.edu

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Robert Zivadinov MD, PhD

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