Adnan Siddiqui MD, PhD, FAHA

Adnan Siddiqui

Adnan Siddiqui
MD, PhD, FAHA

Vice-Chairman and Professor of Neurosurgery

Department of Neurosurgery

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Neurological Surgery; Neuroradiology; Neuroscience

Contact Information
University at Buffalo Neurosurgery
100 High Street
Section B4
Buffalo, New York 14203
Phone: (716) 218-1000
Fax: (716) 859-7480
as257@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

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Professional Summary:

Dr. Adnan H. Siddiqui, is a University at Buffalo Distinguished Professor and Vice Chairman in the Department of Neurosurgery (UBNS) at the State University of New York at Buffalo’s Jacobs School of Medicine and Biomedical Sciences. He joined UBNS in December 2006. Dr. Siddiqui completed fellowship training in Interventional Neuroradiology, Cerebrovascular Surgery and Neurocritical Care from Thomas Jefferson University in Philadelphia. He completed his Neurosurgical residency at Upstate Medical University and received his PhD in Neuroscience from the University of Rochester and medical degree from Aga Khan University in Pakistan. He is a Fellow of the American Association of Neurological Surgeons, American College of Surgeons and American Heart Association. He is profoundly indebted to his mentors Nick Hopkins, Robert Rosenwasser, Charles Hodge and Shirley Joseph in shaping his career as a dual-trained cerebrovascular surgeon, clinician scientist and entrepreneur.

Dr. Siddiqui has special interest and expertise in the performance of complementary microsurgical, radiosurgical and endovascular techniques for the comprehensive management of cerebrovascular conditions. This spectrum of disease includes aneurysms and arteriovenous malformations, as well as dural, cavernous and spinal fistulae. He has special interests in endovascular management of acute ischemic stroke, as well as endovascular and microsurgical management of extracranial and intracranial vascular occlusive disease. Other clinical interests include endovascular management of intractable epistaxis, facial vascular malformations, head, neck, and brain tumor embolization and microsurgical resection of skull base tumors.

Dr. Siddiqui has over 600 peer reviewed publications, more than 50 chapters, almost 50,000 citations and an H index of 89. He is particularly proud of representing Buffalo and the US at most major cerebrovascular conferences around the world with over 400 presentations to date. He has designed, conducted and lead multiple major national and international clinical trials and currently serves as National and International PI for multiple major funded multi-site trials. These efforts have significantly contributed to the success of the department, which was ranked 7th in academic impact in North America by the Journal of Neurosurgery.

He serves as the Chief Executive Officer and Chief Medical Officer at the Jacobs Institute (JI) which is focused on entrepreneurship, development and education opportunities with partners in the medical technology industry including strategics, startups and individual inventors to advance the care of patients with vascular diseases. His goal is to improve the current offerings and translate technologies being developed at the Institute’s idea to reality (i2R) into therapeutic and commercial successes.

He leads the Canon Stroke and Vascular Research Center (CSVRC) at University at Buffalo. This multi-disciplinary center with multiple concurrent major NIH grants, houses neurosurgeons, neuroscientists, physicists and biomedical engineers working collaboratively on cutting edge research focused on neurovascular biology and pathology including stroke and aneurysms, imaging, simulation and hemodynamics. In addition, he serves as the Director of the Neurosurgical Stroke Service at the Gates Vascular Institute in Buffalo, one of the busiest Comprehensive Stroke Services in New York State and the United States.

Dr. Siddiqui has continuously served on multiple scientific and educational committees of American Association of Neurological Surgeons (AANS), Congress of Neurological Surgeons (CNS) and Society of NeuroInterventional Surgery (SNIS). He most recently served as Chairman of the Joint Section of Cerebrovascular Surgery of the AANS and CNS and Secretary for the SNIS (2020-2021). He currently serves on the CNS Executive Council. It has been a major focus for him to achieve consensus between the various organizations involved in fellowship training and credentialing for Neuroendovascular Surgery. He was a founding member of the Neuroendovascular Surgery Advisory Committee (NESAC) for Society of Neurological Surgery’s Committee for Advanced Sub-Specialty Training (CAST) and currently is a member of the American Board of Neurological Surgery’s (ABNS) Central Nervous System Endovascular Surgery Advisory Committee (CESAC). This has been an extremely important role, which is profoundly affecting the training and education pathways of neuroendovascular specialists.

He serves as a Neurosurgeon Director on the Executive Committee of the SNIS Patient Safety Organization which runs the NVQI-QOD Quality Outcomes Registry. He has also assumed the role of Co-Chair of the Neurological Devices Working group for the Medical Device Industry Consortium (MDIC), a not-for-profit group consisting of FDA, CMS and Industry partners dedicated to resuming Early Feasibility Studies (EFS) also known as First in man studies in the United States.

In recognition of his achievements, Dr. Siddiqui has been honored with the 2021-2022 SUNY Chancellor’s Award for Excellence in Scholarship and Creative Activities, the invitation to present the M. Gazi Yasargil Lecture at the AANS Annual Meeting in 2023, and has recently received a Distinguished Professorship from the University at Buffalo.

All these efforts as a microsurgeon, endovascular surgeon, scientist and trialist, have allowed Dr. Siddiqui to gain unique insights into a critical and rapidly evolving specialty. At the same time, these endeavors have required significant collaborations resulting in strong and trusting relationships with fellow neurosurgeons, neurologists, neuroradiologists, scientists, engineers, regulatory officers and industry.

Dr. Siddiqui is married and has three children. He is a proud Buffalonian who is challenged and invigorated by taking care of neurosurgical patients and their families. He is most gratified by his pedagogical responsibilities, which allow him the opportunity to teach medical students, residents and fellows. He is grateful for the opportunity to work at University at Buffalo’s Department of Neurosurgery and Canon Stroke & Vascular Research Center, Gates Vascular Institute and Jacobs Institute, facilities with some of the world's best technologies, and greatest vascular specialists, researchers and biomedical engineers who are working together to advance the care of vascular diseases.

Education and Training:

  • Fellowship, Cerebrovascular Surgery, Thomas Jefferson University (2006)
  • Residency, Neurosurgery, Upstate Medical University, State University of New York (2005)
  • Residency, Neurosurgery, Upstate Medical University, State University of New York (2004)
  • PhD, Neuroscience, University of Rochester (2003)
  • Internship, Upstate Medical University, State University of New York (1999)
  • MS, University of Rochester School of Medicine and Dentistry (1997)
  • MD, Aga Khan University (1992)
  • Fellowship, University of Rochester School of Medicine and Dentistry, Division of Neurological Surgery

Employment:

  • CEO, Jacobs Institute (2021-present)
  • Professor of Neurosurgery, Neurosurgery, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2014-present)
  • Director of Neuroendovascular Fellowship, Kaleida Health / UB Neurosurgery (2013-present)
  • Director, Canon Stroke and Vascular Research Center, University at Buffalo (2013-present)
  • Director of Neurosurgical Research, Neurosurgery, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2008-present)
  • Director of Neuroendovascular Critical Care, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2007-present)
  • Associate Professor of Neurosurgery, Neurosurgery, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2011–2014)
  • Assistant Professor of Neurosurgery, Neurosurgery, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2007–2011)
  • Assistant Professor of Neurosurgery, Radiology and Neuroscience & Physiology, Neurosurgery, SUNY Upstate Medical University (2006)
  • Instructor of Neurosurgery, Neurosurgery, SUNY Upstate Medical University (2005–2006)

Awards and Honors:

  • Buffalo Business First Power 250 List (2025)
  • Buffalo Business First Power 100 Business Leaders of Color (2024)
  • UB Distinguished Professor (2023)
  • Presentation of the M. Gazi Yasargil Lecture (2023)
  • SUNY Chancellor's Award (2022)
  • George Thorn Young Investigator Award, University at Buffalo (2012)
  • Business First Top 50 Physicians in Western New York (2010)
  • Arnold P. Gold Foundation National Award for Teaching (2004)
  • National Research Service Award in Neuroscience (1997)
  • National Research Service Award in Neuroscience (1996)
  • Bartlett Award for best presentation, University of Rochester (1994)

Research Expertise:

  • Endovascular management of acute ischemic stroke, as well as endovascular and microsurgical management of extracranial and intracranial vascular occlusive disease: Endovascular management of acute ischemic stroke, as well as endovascular and microsurgical management of extracranial and intracranial vascular occlusive disease
  • Endovascular management of intractable epistaxis, facial vascular malformations, head, neck, and brain tumor embolization and microsurgical resection of skull base tumors.: Endovascular management of intractable epistaxis, facial vascular malformations, head, neck, and brain tumor embolization and microsurgical resection of skull base tumors.
  • Performance of complementary microsurgical, radiosurgical and endovascular surgical techniques: Surgical Techniques for the comprehensive management of cerebrovascular conditions

Research Centers:

  • Clinical and Translational Research Center (CTRC)
  • Toshiba Stroke Research Center

UB 2020 Strategic Strengths:

  • Health and Wellness Across the Lifespan

Grants and Sponsored Research:

  • August 2013–July 2016
    Micro-Radiographic Imager for Neuroovascular Interventions
    NIH
    Role: Co-Investigator
  • February 2009–February 2014
    Hemodynamic Induction of Pathologic Remodeling Leading to Intracranial Aneurysms
    National Institutes of Health/National Institute of Neurological Disorder and Stroke
    Role: Co-Investigator
    $1,733,595

Patents:

  • CLOT RETRIEVAL SYSTEM FOR REMOVING OCCLUSIVE CLOT FROM A BLOOD VESSEL CLOT RETRIEVAL SYSTEM FOR REMOVING OCCLUSIVE CLOT FROM A BLOOD VESSEL (2022)

Journal Articles:

See all (325 more)

Books and Book Chapters:

  • Siddiqui A. (2010) Handbook of Angioplasty and Stenting Procedures. In: Intracranial and Vertebral Artery Angioplasty and Stenting.
  • Siddiqui A. (2009) Diagnostic Methods in the Catheterization Laboratory: A Practical Approach for Specific Clinical Situations. In: Important Key Points of Intracranial Angiography for the Interventional Cardiologist. Informa Healthcare
  • Siddiqui A. (2008) Current Surgical Therapy, 9th Edition. In: Management of Recurrent Carotid Stenosis. Mosby-Elsevier, 784-791.
  • Siddiqui A. (2007) Intracranial Arteriovenous Malformations. In: Endovascular Therapy: Indications, Complications, and Outcome. Informa Healthcare, 407-427.
  • Siddiqui A. (2006) Neurosurgical Operative Atlas 2E: Vascular Neurosurgery. In: Previously Coiled Endovascularly-treated Aneurysms. Thieme
  • Siddiqui A. (2003) Endoscopic Spine Surgery and Instrumentation and Percutaneous Procedures. In: Endoscopic Cervical Laminoforaminotomy and Discectomy (MED). Thieme
  • Siddiqui A. (2002) Image-Guided Neurosurgery. In: Robotic Microscopes. Thieme
  • Siddiqui A. (1900) Cardiovascular Interventions in Clinical Practice. In: Interventional Management of Acute Ischemic Stroke. Wiley Blackwell
  • Siddiqui A. (1900) Hemorrhagic and Ischemic Stroke: Surgical, Interventional, Imaging, and Medical Approaches. In: Endovascular Thrombolysis: Pharmacologic and Mechanical. Thieme
  • Siddiqui A. (1900) Endovascular Surgery, 4th Edition. In: Complication Management in Carotid Stenting. Elsevier (Saunders)
  • Siddiqui A. (1900) Youmans Textbook of Neurological Surgery, 6th edition. In: Carotid Artery Stenting. Elsevier
See all (1 more)

Abstracts:


Professional Memberships:

  • American Society of Neuroimaging (2008–present)
  • AANS-CNS Section on Cerebrovascular Surgery (2005–present)
  • AANS-CNS Section on Neurotrauma and Critical Care (2005–present)
  • AANS-CNS Section on Tumors (2005–present)
  • American Association of Neurological Surgeons (1999–present)
  • Congress of Neurological Surgeons (1999–present)
  • American Epilepsy Society (1995–1998)
  • Society for Neuroscience (1993–present)

Presentations:

  • "“Endovascular treatment of chronically occluded sinus causing intracranial hypertension”" 1. Bi-Neurovascular Symposium (2024)
  • "Complications of Angiography – Avoidance & Management." Endovascular 101: Introduction to Cerebral Angiography & Endovascular Surgical Neuroradiology (2013)
  • "“Interventions for Acute Stroke: Who Should Do These, and How are They Done Best?”" New Cardiovascular Horizons 14th Annual Conference (2013)
  • "New and Emerging Endovascular, Microsurgical Therapies in the Treatment of Stroke and Cerebrovascular Conditions”" Kaleida Health Seminar for Nurses; Kaleida Health (2013)
  • "“Latest in Stroke Intervention”" Cattaraugus County Medical Society Meeting (2013)
  • "“New and Emerging Endovascular, Microsurgical Therapies in the Treatment of Stroke and Cerebrovascular Conditions”" 3rd Annual Stroke Education Day, Essentials of Stroke Care Seminar presented by Faxton St. Luke’s Healthcare (2013)
  • "“Ischemic & Hemorrhagic Stroke (CV Insufficiencies)” and “Intracranial Aneurysms.”" CNS SANS MOC Board Review Course; CNS; Vascular (2013)
  • "Clinical Trials on Cerebral Stroke" ISNVD 3rd Annual Meeting; ; Acute Stroke Management (2013)
  • "“PREMISE, A Blinded, Sham Controlled Trial for CCSVI.”" 3rd SNIS International Endovascular Stroke Conference; SNIS; Stroke Research Updates (2013)
  • "Comparison of IVUS to gold standard catheter venography for detection of extra-cranial venous abnormalities indicative of CCSVI: results of the PREMiSe study.”" ISNVD 3rd Annual Meeting; ; Session 2 CCSVI Clinical Trials (2013)
  • "Evolution of Cerebrovascular Intervention in a Regional Comprehensive Cerebrovascular (Stroke) Center" Department of Neurosurgery Grand Rounds, Children’s Hospital Boston/ Harvard Medical School; Children’s Hospital Boston/ Harvard Medical School (2009)
  • "Interventional Neuroradiology Treatments for Treatment of Acute Stroke" PEP Program & Tiantan Advanced Training Course (2009)
  • "Treatment of Complex Intracranial Aneurysms" PEP Program & Tiantan Advanced Training Course (2009)
  • "Stent Reconstruction for Acute Intracranial and Extracranial Occlusive Disease" Neurosurgery Grand Rounds, University of Texas Southwestern (2009)
  • "Telemedicine for a Successful Stroke Program" Neurosurgery Grand Rounds, University of Texas Southwestern (2009)
  • "Cavernous Sinus Triangle" Grand Round Presentations, Millard Fillmore Gates Hospital (2009)
  • "Surgical Treatment of Spinal Arteriovenous Fistulas: A Consecutive Series of 154 Patients" AANS Annual Meeting (2009)
  • "Tools of the Trade" Neurosurgery Residents Education Summit. University of Florida (2009)
  • "Coiling of Wide Neck Aneurysm with Enterprise" Second Huashan International Conference on Surgery for Cerebral & Spinal Vascular Diseases (2009)
  • "Treatment of Intracranial Aneurysm with the Enterprise Stent: A Multicenter Registry" Second Huashan International Conference on Surgery for Cerebral & Spinal Vascular Diseases (2009)
  • "Treatment Option of Intracranial Dissecting Aneurysm" Second Huashan International Conference on Surgery for Cerebral & Spinal Vascular Diseases (2009)
  • "Endovascular Treatment for Stoke: Now and the Future" Neurosurgery Residents Education Summit (2009)
  • "Lateral Approaches to Skull Base" Grand Round Presentations, Millard Fillmore Gates Hospital (2009)
  • "Flow Measurement for Patient Selection in Ischemic Disease “Flow is Not Enough" 3rd International Symposium on Flow Measurement in Cerebrovascular Surgery (2009)
  • "The Current State of Endovascular Treatment for Intracranial Atherosclerotic Occlusive Disease “Drug-Eluting Stents: Role in the Treatment of Intracranial Disease?" International Stroke Conference (2009)
  • "AVF’s and C-C Fistulas" Grand Round Presentations, Kenmore Mercy Hospital (2009)
  • "Innovative Uses of Telehealth in the Treatment of Acute Stroke; “An Urban/ Suburban Telestroke Case Study" American Heart Association and American Stroke Association Congressional Briefing, Innovative Uses of Telehealth in the Treatment of Acute Stroke (2008)
  • "Intracranial Stenting for Acute Stroke" International Intracranial Stent Symposium (ICS) and Anatolian Course of Interventional Neuroradiology (ACINR) (2008)
  • "Long Term Follow Up Results of Carotid Stenting: Should CS Replace CE?" International Intracranial Stent Symposium (ICS) and Anatolian Course of Interventional Neuroradiology (ACINR) (2008)
  • "Emergency Medicine Grand Rounds: Acute Stroke Lecture" Millard Fillmore Gates Hospital (2007)
  • "Endovascular Management of Acute Stroke" The 23rd Annual Meeting of the Japanese Society for Neuroendovascular Therapy (2007)
  • "Endovascular Management of Dural and Carotid Cavernous Arteriovenous Fistulae" Grand Round Presentations, Millard Fillmore Gates Hospital (2007)
  • "Management of Strokes: What is a comprehensive Stroke Center?" EMS Training Lecture, Millard Fillmore Gates Hospital (2007)
  • "Introduction to Endovascular Neurosurgery" CNS Annual Meeting (2007)
  • "Virtual Visit Technology and Neurosurgery" CNS Annual Meeting (2007)
  • "Stroke Awareness – Signs, Symptoms, Treatment and Recovery" Canterbury Woods Retirement Community (2007)
  • "Stroke Q&A" The Kathy Weppner Show, WBEN 930 AM (2007)
  • "Endovascular Management of Ischemic and Hemorrhagic Stroke" AANS Annual Meeting (2007)
  • "Management, Complications and Avoidance Strategies of Interventional Neurovascular Disease" AANS Annual Meeting (2007)
  • "Endovascular management of Acute Stroke" 7th Annual Contemporary Issues in Emergency Medicine, Upstate Medical University College of Medicine (2007)
  • "Cerebrovascular Anatomy and its Clinical Correlation" Neuroscience course guest lecturer, Upstate Medical University (2005)
  • "Spontaneous Clinical and Radiographictriculoperitoneal Shunt Malfunction Resolution of a Ven" New England Neurosurgical Society, Annual Meeting (2004)
  • "Traumatic Pericallosal Artery Aneurysm—A Rare Complication of Transcallosal Surgery" New England Neurosurgical Society, Annual Meeting (2004)
  • "Are There Anatomical Correlates to Cortical Lesion Induced Functional Plasticity?" Neurosurgery Research Day, Upstate Medical University (2003)
  • "Does Amphetamine Enhance Lesion Induced Cortical Plasticity?" Neurosurgery Research Day, Upstate Medical University (2003)
  • "Pilot Studies on the Molecular Basis for Cortical Plasticity" Neurosurgery Research Day, Upstate Medical University (2003)
  • "Reorganization of Hippocampal Circuitry in Kainate Induced Epilepsy" Neurosurgery Research Day, Upstate Medical University (2002)
  • "Status Epilepticus Induced Cell Proliferation in the Adult Rat Hippocampus" De Kiewet Fellowship Program Meeting, University of Rochester (2001)
  • "Glutamate Receptor Immunocytochemistry Following Kainate Induced Status in Rats" University of Rochester, Seminar in the Neurosciences (1996)
  • "Immunocytochemical Localization of Selective Glutamate Receptor Subunits in Kainic Acid Treated Rats" Society for Neuroscience, Rochester Chapter (1996)
  • "The Effects of Adrenalectomy on Dentate Granule Cells: Insights into Hippocampal Role in Stress and Aging" University of Rochester, Seminar in the Neurosciences (1996)
  • "6-Hydroxydopamine and Regulation of Tyrosine Hydroxylase Expression in PC12 Cells" University of Rochester, Seminar in the Neurosciences (1995)
  • "Dopaminergic Projection from the Zona Incerta to the Neocortex" Society for Neuroscience, Rochester Chapter (1995)
  • "Pilot Study on Adenoviral Gene Therapy for Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)" University of Rochester, Seminar in the Neurosciences (1995)
  • "“MMA Embolization Trials”" 8th Annual South Texas Comprehensive Stroke Symposium
  • "“Role of MMA Embolization and Beyond”" Bi-Neurovascular Symposium, Busan, South Korea
  • "Charting New Territories: Innovation Trends in Brain Science" TCT Annual Meeting
  • "Current clinical needs in telesurgery: Cardiac and neurovascular stenting and clot removal" SRS Telesurgery Meeting
  • "ICAD Rescue: Why? When? Where?" SNIS Annual Meeting
  • "New paradigm for revascularization of chronic cervical internal carotid occlusions switching from surgical to endovascular bypass" OCIN Annual Meeting
  • "Our experience with venous pressure monitoring and stenting in patients with idiopathic intracranial hypertension" OCIN Annual Meeting
  • "Special Debate - conflict between and importance of regulation of innovation in neurosurgery" American Academy of Neurological Surgery (AAcNS)
  • "What’s Next for Acute Ischemic Stroke?" Iranian Stroke Congress
  • "With Acute Strokes, What Is New With Endovascular Intracranial Techniques For Arterial Clot Removal: How Can Artificial Intelligence (AI) And Intraarterial" VEITH Annual Meeting
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Service Activities:

  • Charing Cross Carotid Executive Board Member for 2025 Annual Meeting; Charing Cross Carotid Executive Board Member for 2025 Annual Meeting (2025–present)
  • (2025)
  • World Federation of Interventional and Therapeutic Neuroradiology (WFITN) Elected Member-at-large of the Executive Committee October 2024; World Federation of Interventional and Therapeutic Neuroradiology (WFITN) Elected Member-at-large of the Executive Committee October 2024 (2024–present)
  • Named Fellow of the Congress of Neurological Surgeons (FCNS) – 2024; Named Fellow of the Congress of Neurological Surgeons (FCNS) – 2024 (2024–present)
  • European Society of Minimally Invasive Neurological Therapy, Member; European Society of Minimally Invasive Neurological Therapy, Member (2023–present)
  • Society of Robotic Surgery – Board of Directors; Society of Robotic Surgery – Board of Directors (2023–present)
  • Yasargil Microneurosurgery Academy, Founding Member; Yasargil Microneurosurgery Academy, Founding Member (2023–present)
  • ; AKG Art Gallery Board Member (2021–present)
  • ; Serve as Student Preceptor / Mentor (2018–present)
  • Director of Neuroendovascular Fellowship; Director of Neuroendovascular Fellowship (2014–present)
  • Director of Neuroendovascular Research; Director of Neuroendovascular Research (2008–present)
  • Director of Neurosurgical Stroke Services; Director of Neurosurgical Stroke Services (2008–present)
  • Institutional Research Review Board; Alternate Member (2008–present)
  • ; Advisory Council for the Clinical Research Center/Clinical Trials Office
  • Member of the Stroke Steering Committee; Member of the Stroke Steering Committee
  • ; Search Committees for Faculty and Dean of Medicine

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Contact Information

University at Buffalo Neurosurgery
100 High Street
Section B4
Buffalo, New York 14203
Phone: (716) 218-1000
Fax: (716) 859-7480
as257@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD