Department of Medicine
Professor and Chief, Gastroenterology, Hepatology, and Nutrition
Gastroenterology; Infectious Disease; Liver (Hepatology)
I became Chief of GI in September 2012 after 12 years on the faculty at Weill Cornell Medical College in NYC. A major pursuit at UB is developing or expanding clinical, educational, and research opportunities in liver diseases. Clinically, we have recently tripled the capacity of the Erie County Medical Center liver clinics, which specialize in viral hepatitis. We have established comprehensive liver clinics at Buffalo General Medical Center that evaluate liver disease patients referred from throughout Western New York (WNY). We also work closely with faculty at the VA of WNY to deliver uniformly excellent clinical care and to conduct collaborative research. We also have several clinical trials of new therapies for viral hepatitis and other forms of liver disease.
I teach GI fellows, residents, and students in outpatient and inpatient settings. I also teach 1st and 2nd year medical students in small groups. I am very interested in mentoring, and presently supervise several residents and fellows in clinical research as well as in my laboratory. In fact, some of my former trainees are presently division faculty members.
I have funded research programs in translational and clinical research. Translational research is the generation of research questions based on clinical observations. In translational research, we have developed techniques for human liver sampling in order to understand what happens in the liver compartment during treatment and to develop ways to measure liver drug concentration. Basing drug dosing on liver instead of plasma concentration may be very important because of the close relationship between drug efficacy and toxicity. In the area of clinical research, we are studying care models for viral hepatitis. Presently, we are conducting a study sponsored by the CDC Foundation assessing telemedicine for treatment of hepatitis C in patients in treatment for substance use.