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Arie                           Weinstock

Arie L. Weinstock M.D.

Department of Neurology

Professor of Clinical Neurology; Medical Director, Child Neurology Division; Director, Epilepsy Program and Long Term Monitoring

Specialty/Research Focus

Child Neurology; Epilepsy; Neurology

 
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Professional Summary:

I joined the Department of Neurology and the University at Buffalo in July 1998 with the goal to develop the EEG and pediatric epilepsy program. Prior to that time, I completed residencies in Pediatrics at the University of Tel-Aviv and at Rainbow Babies Case Western University, as well as fellowships in Child Neurology and in Epilepsy and Clinical Neurophysiology at the Cleveland Clinic Foundation.

I currently serve as Director of the Division of Child Neurology, the Epilepsy Monitoring Unit as well as the EEG laboratories for Kaleida Health. I was promoted to Professor in Clinical Neurology in March 2014. I serve as the main instructor for EEG and Epilepsy for neurology residents and clinical neurophysiology fellows, and mentored numerous residents and fellows for research projects.

The child neurology division was recognized by the “US NEWS and WORLD REPORT” as one of the Top 50 Children’s Hospital in the field of Neurology/Neurosurgery in 2013 and 2011. Our 8-bed epilepsy monitoring unit (EMU) was recognized as a Level IV NAEC level for 4 years in a row (highest possible) by the National Association of Epilepsy Centers (NAEC). The EMU was awarded a $1,000,000 grant by the Cummings Foundation to build a new 12-bed Epilepsy Monitoring Unit in the John R. Oishei Children’s Hospital, Buffalo, NY.

My interests in child neurology and epilepsy have focused on management of refractory epilepsy in children, epilepsy surgery and EEG. I am board certified in child neurology, clinical neurophysiology and epilepsy. I read evoke potentials and perform Quality Assurance of EEG‘s at various hospitals in the city of Buffalo.

My main research is relate to the diagnosis and management of refractory epilepsy and epilepsy surgery. I have been the site investigator for many Pharma and NINDS sponsored studies on novel anti-epileptic drug therapies, particularly as they relate to pediatric epilepsy, and was the PI of various investigator initiated studies. I am passionate in the education of epilepsy and EEG and guiding medical students, neurology residents and clinical neurophysiology fellows into their careers while promoting the field of epilepsy.


Professor of Clinical Neurology
State University of New York at Buffalo
Medical Director, Child neurology Division
Director, Epilepsy Program and Long Term Monitoring
Women and Children’s Hospital of Buffalo
219 Bryant Street
Buffalo, New York 14222
Phone: (716) 878-7840, Fax: (716) 878-7326
E-mail: alw4@buffalo.edu

Education and Training:
  • MD, Technion, Israel Institute of Technology
  • Internship, Carmel Hospital
  • Residency, Hasharon Hospital and Tel-Aviv University
  • Residency, Rainbow Babies and Children Hospital, University Hospital
  • Fellowship, Cleveland Clinic Foundation
  • Fellowship, Cleveland Clinic Foundation
Employment:
  • Clinical Professor, Director, Child Neurology & Epilepsy, School of Medicine & Biomedical Sciences, Neurology, University at Buffalo (2014-present)
  • Medical Director Child Neurology Division, Kaleida Health, Child Neurology Division, Kaleida Health (2010-present)
  • Medical Director Adult EEG Laboratories, Kaleida Health (2010-present)
  • EEG Training Director for Clinical Neurophysiology Fellowship/Neurology, University at Buffalo (2000-present)
  • Director, Associate Professor of Clinical Neurology, Women & Children's Hospital of Buffalo, Neurology, Women & Children’s Hospital of Buffalo (1998–2010)
  • Medical Director, Child Neurology Division, Women & Children's Hospital of Buffalo, Women & Children‘s Hospital of Buffalo (1998–2010)
  • Medical Director, Long Term Monitoring & Pediatric Epilepsy/EEG, Long Term Monitoring and Pediatric Epilepsy/EEG, Women & Children‘s Hospital of Buffalo (1998–2010)
Awards and Honors:
  • US News and World Report: Top Doctor (2013)
  • Cummings Foundation Grant:Epilepsy Division (2013)
  • Teacher of the Year Award (2005)
  • Level IV NAEC
  • Top Docs in Child Neurology 2009, 2010, 2011, 2012, 2013

Research Expertise:
  • Epilepsy: With special interest in refractory epilepsy, pediatric epilepsy, and epilepsy surgery
Grants and Sponsored Research:
  • January 2006–November 2014
    Childhood Absence Epilepsy RX, PK-PD-Pharmacogenetics
    NINDS
    Role: Principal Investigator
  • January 2013
    Clobazam Effect on Seizure Control and Quality of Life
    Lundbeck, LLC
    Role: Principal Investigator
  • October 2003
    Use of Lorazepam for the Treatment of Pediatric Status Epilepticus: A Randomized, Double-Blinded Trial of Lorazepam and Diazepam
    NICHD
    Role: Co-Investigator
  • Jog for Jake
    Role: Co-Investigator
    $5,000
  • Source Analysis of Interictal Sharp Waves in Focal Epilepsy
    Wildermuth/Variety Club of Buffalo & Jog for the Jake, Jacobs Neurological Institute
    Role: Principal Investigator
  • Safety and efficacy of Levetiracetam (LEV) Administration in Infantile Spasms
    UCB Pharma
    Role: Principal Investigator
  • Vagal Nerve Stimulation and Immune System Regulation in Patients with Intractable Epilepsy
    Wildermuth/ Variety Club of Buffalo, Jog for the Jake, and Jacobs Neurological Institute
    Role: Principal Investigator
See All (7 Total) >

Journal Articles:
  • Goldberg H, Weinstock A, Bergsland N, Dwyer MG, Farooq O, Sazgar M,Poloni G, Treu C, Weinstock-Guttman B, Ramanathan M and Zivadinov R.. MRI segmentation analysis in temporal lobe and idiopathic generalized epilepsy.. BMC Neurology. 2014; 14(131).
  • Menascu S, Weinstock A, Farooq O, Hoffman H, Cortez MA.. EEG and Neuroimaging Correlations in Children with Lissencephaly.. Seizure. 2013; 22(3).
  • Farooq, O; Hartley-McAndrew M, Memon, A; Weinstock, A.. A Pediatric Astrocytoma Causing Intractable Epilepsy. Journal of Neurology and Translational Neuroscience. 2013; 1(2).
  • Kardys A, Weinstock-Guttman B, Dillon M, Masud M, Weinstock N, Mahfooz N, Lang J, Weinstock A, Lincoff N, Zivadinov R, Ramanathan, M.. Cholesterol Affects Retinal Nerve Fiber Layer Thickness in Multiple Sclerosis Patients with Optic Neuritis. European Journal of Neurology. 2013; 20(9).
  • Weinstock A, Ruiz M, Gerard D, Toublanc N, Stockis A, Dilley D, Farooq O, Elgie MJ, Schiemann J.. Safety and Pharmacokinetic Studies of Intravenous Levetiracetam in Children with Epilepsy. Journal of Child Neurology. 2013; 28(11).
  • Glauser TA, Cnaan A, Shinnar S, Hirtz D, and the Childhood Absence Epilepsy Study Team. (Weinstock A is a member of the Childhood Absence Epilepsy Study Group listed in the appendix). Ethosuximide, Valproic Acid, and Lamotrigine in Childhood Absence Epilepsy: Initial Monotherapy Outcomes at 12 Months.. Epilepsia. 2013; 54(1).
  • Karmon Y, Morrow SA, Weinstock A, Hojnacki D, Weinstock-Guttman B.. Limb Ataxia Originating From Peri-Central Sulcus Demyelinating Lesion in Multiple Sclerosis. Journal of Neurological Sciences. 2012; 320(1-2).
  • Hartley-McAndrew M, Weinstock AL. Developments in Neuroimaging in Autism: Aims in Approaching a Diagnostic Fingerprint. The North American Journal of Medicine and Science. 2012; 5(3).
  • Majumdar I, Hartley-McAndrew ME, Weinstock AL. Central nervous system herpes simplex virus infection in afebrile children with seizures. J Child Neurol. 2012; 27(4).
  • Majumdar I, Hartley-McAndrew M, Weinstock A. CNS Herpes Virus Infection in Afebrile Children with Seizures. Journal of Child Neurology. 2012; (4).
  • Hartley-McAndrew M., Weinstock, A. A Review of the Neurobiological Basis of Autism. The North American Journal of Medicine and Science. 2011; 4(3).
  • Glauser T., Cnaan A., Shinnar S., et al, Weinstock AL. Valproic Acid and Lamotrigine in Childhood Absence Epilepsy. The New England Journal of Medicine. 2010; 362.
  • Hartley-McAndrew M, Weinstock AL. Autism Spectrum Disorder: Correlation Between Aberrant Behaviors, EEG Abnormalities and Seizures. Neurology International. 2010; 2(1).
  • Yeh E, Weinstock-Guttman B, Lincoff N, Reynolds J, Weinstock A, Madurai N, Agarwal N, Buch P, Karpinski M. Retinal Nerve Fiber Thickness in Inflammatory Demyelinating Diseases of Childhood Onset.. Mult Scler. 2009; 15(7).
  • Piña-Garza JE, Nordli Dr Jr, Rating D, Yang H, Schiemann-Delgado J, Duncan B, Weinstock AL. Adjunctive Levetiracetam in Infants and Young Children with Refractory Partial-Onset Seizures. Epilepsia. 2009; 50(5).
  • Dai A, Weinstock, A. Post-Ictal Paresis in Benign Rolandic Epilepsy of Childhood. Journal of Child Neurology. 2005; 10.
  • Wood B, Haque S, Weinstock A, and Miller B.. Pediatric Stress Related Seizures: Conceptualization, Evaluation and Treatment of Non-Epileptic Seizures in Children and Adolescents. Current Opinion in Pediatric Journal. 2004; 16(5).
  • Weinstock A, Giglio P, Kerr SL, Cohen ME. Hyperkinetic Seizures in Children. Journal of Child Neurology. 2003; 18(8).
  • Weinstock-Guttman B, Baier M, Stockton R, Weinstock A, Justinger T, Munschauer F, Brownscheide C, Williams J, Fisher E, Miller D and Rudick R.. Pattern Reversal Visual Evoke Potentials as a Measure of Visual Pathway Pathology in Multiple Sclerosis. Multiple Sclerosis. 2003.
  • Weinstock A, Giglio P, Bakshi R, Cohen ME, Januario J, and Balos L.. Diffuse MRI White Matter Changes in a 15-Year Old Boy with Mitochondrial Encephalomyopathy. Journal of Child Neurology. 2002; 17.
  • Maydell BV, Wyllie E, Akhtar N, Kotagal P, Powaski K, Cook K, Weinstock A, Rothner AD.. Efficacy of the Ketogenic Diet in Focal Versus Generalized Seizures. Pediatric Neurology. 2001; 25(3).
See All (21 Total) >
Abstracts:
  • Fidller A., Teter B, Weinstock A. Triphasic Waves and Epileptiform Correlates on Electroencephalogram. 2014.
  • Boudreau M, Li P, Li V, Weinstock, A. Ictal SPECT Activation in a Case of Gelastic Seizures Caused by a Low Grade Glioma in the Posteriolateral Temporal Lobe. Epilepsia. 2013.
  • Shahdad N, Weinstock A. Photic Induced Seizures and Photoparoxysmal Response. Epilepsia. 2013.
  • Purushotam H, Weinstock A, Kerr SL, Finnegan SG. Outcome and Challenges in Treating Infantile Spasms with High Dose Oral Prednisolone. Epilepsia. 2012.
  • Riggins N, Li P, Li V, Farooq O, Weinstock A. Epilepsy Surgery in MRI-Negative Sound-Induced Startle Epilepsy. Epilepsia. 2012.
  • Karmon Y, Morrow S, Weinstock A, Hojnacki D, Weinstock-Guttman B.. Limb Ataxia Originating from Per-Central Sulcus Demyelinating Lesion In Multiple Sclerosis Patients. 2012.
  • Jaisani Z, Ramanathan M, Miletich R, Weinstock A.. The Yield of FDG-PET in Patients with Temporal Lobe Epilepsy and Post Surgical Outcome. 2011.
  • Weinstock A, Ruiz M, Gerard D, Toublanc N, Stockis A, Schiemann J.. Two Open-Label, Single-Arm, Multi-Center, Safety, Tolerability and Pharmacokinetic Studies of Intravenous Levetiracetam in Children (>1 month to 16 years old) with Epilepsy. 2011.
  • Goldberg H, Weinstock A, Dwyer M, Bergsland N, Sazgar M, Poloni G, Zivadinov R.. Automated Segmentation of Brain MRI for Quantification of Cortical and Subcortical Atrophy in Patients with Temporal Lobe Epilepsy. 2011.
  • Weinstock A, Weinstock-Guttman B, Supala Berger A, Sazgar M, Elgie MJ, Ramanathan M.. Vagal Nerve Stimulation and the Immune Modulation in Patients with Refractory Epilepsy. 2011.
  • Agarwal N, Ramanathan M, Hartley-McAndrew M, Gillogly C, Weinstock A. Ketogenic Diet: Clinical Predictors for Significant Seizure Control. 2010.
  • Arsnow C, Wehbeh R, Buchlis J, Weinstock-Guttman B, Weinstock A. Bone Mineral Density in Ambulatory Pediatric Patients with Epilepsy. 2010.
  • Weinstock A., Wehbe R., Teter B., Weinstock-Guttman B.. Inadequate Vitamin D Levels in Pediatric Patients with Epilepsy. 2010.
  • Wehbeh R., Weinstock-Guttman B., Teter B. and Weinstock A. Vitamin D Status in Pediatric Patients with Epilepsy: Effect of Anti-Epileptic Drugs. Epilepsia. 2009.
  • Masters L.P, Weinstock A. The Use of Levetiracetam for Treatment of Infantile Spasms. 2008.
  • Hartley-McAndrew M.E., Weinstock A., Weinstock-Guttman B., Sazgar M., Li V, Rozelle C., and Ramanathan M.. Hippocampal Gene Expression as Predictors for Surgical Outcome in Patients with Mesial Temporal Sclerosis. 2008.
  • Majumdar I., and Weinstock A.. Incidence of CNS Herpes Infections in Children Presenting with Afebrile Seizures.. 2008.
  • Masters L.P, Weinstock A. De Novo Absence Status Epilepticus in Childhood. 2007.
  • Hartley-McAndrew M.E., Weinstock A.. Is There a Correlation Between Certain Behaviors, EEG Abnormalities and/or Seizures in Children with Autism Spectrum Disorder?. 2007.
  • Yeh EA, Ramanathan M, Lincoff N, Weinstock A, Weinstock-Guttman B.. Visual Function as Measured by Optical Coherence Tomography and Visual Evoke Potentials in Pediatric Patients with Acquired Demyelinating Diseases. Annals of Neurology. 2007.
  • Weinstock A, Ramanathan M, Tamano de Blanco ME, Li Veetai, Zhang L, Ostrow P, Weinstock-Guttman B. Increased Expression of Complement Component 5 and Glial Activation Genes in Tissue and Peripheral Blood Mononuclear Cells in Patients with Intractable Temporal Lobe Epilepsy.. 2004.
  • Zhang L, Dwyer M, Kerr S, Finnegan S, Zivanidov R, Weinstock A. Source Analysis of Interictal Sharp Waves in Focal Epilepsy. 2004.
  • Weinstock A, Ramanathan M, Tamano de Blanco ME, Li Veetai, Zhang L, Ostrow P, Weinstock-Guttman B. Gene Expression Analysis of Temporal Lobe Tissue and Peripheral Blood Mononuclear Cells in Patients with Temporal-Lobe Epilepsy. Neurology. 2004.
  • Radovick V, Weinstock A, Gunther M, Kerr SL, Guterman L. Video EEG Evaluation During Intra-Carotid Amobarbital Test. Epilepsia. 2003.
  • Weinstock A, Minhas J, Mehr Aftab, Cohen ME. Clinical Outcome of Children with Prolonged Runs of 3 Hz Spike Wave Complex on EEG. Epilepsia. 2003.
  • Weinstock A, Giglio P, Kerr SL, Cohen ME. Hypermotor Seizures in Children. Journal of Neurology. 2000.
  • Weinstock A, Kerr S, Block S, Rohleder K. The Use of a Computerized EEG Data-Base. 2000.
  • Dai A, Weinstock A, Venkataraman A, Kerr S, Cohen EM. Post-Ictal Paresis in Benign Rolandic Epilepsy. Epilepsia. 2000.
  • Weinstock -Guttman B, Baier M, Weinstock A, Stockton T, Justinger T, Cutter G, Rudick R, Jacobs L. The Predictive Value of Pattern Visual Evoked Potential as a Surrogate of Visual Function in Multiple Sclerosis. Annals Of Neurology. 2000.
  • Weinstock -Guttman B, N. Lincoff, Weinstock A, R Stockton, Jacobs L. Predictive Factors in Recovery From Optic Neuritis. Neurology. 1999.
  • Dai A, Weinstock A, Kerr SL, Venkataraman A, Cohen ME. EEG Analysis of Central and Centro-Temporal Sharp Waves. 1999.
  • Weinstock A, Weinstock -Guttman B, Stockton R, Jacobs L. Use of Pattern Visual Evoke Potential as a Physiological Recovery for Optic Neuritis. 1999.
  • Weinstock A, Wyllie E, Kotagal P, Powaski K, Gilliam F, Bebin M, and A. David Rothner. Health Related Quality of Life in Children on the Ketogenic Diet. Epilepsia. 1997.
  • Cohen BH, Weinstock A, Kotagal P and Wyllie E. Disorders of Oxidative Metabolism Presenting to the Video-EEG Monitoring. Epilepsia. 1997.
  • Weinstock A, Rothner AD, and Cohen BH. Vascular Complications of Neurofibromatosis Type-1. Annals Neurol. 1996; 40(2).
  • Weinstock AL, Rothner AD. Trauma triggered migraine: A cause for transient neurological deficits after minor head trauma in children. Neurology. 1995.
  • Weinstock AL, Cohen BH, Moorjani B, Ruggieri P, Rothner AD. Spinal Neurofibromatosis: An indistinct type of Neurofibromatosis. 1995.
  • Weinstock A, Cohen BH, Kaplan A, Ruggieri P, Rothner AD.. Brain stem lesions in children with Neurofibromatosis type-1. Annals Neurol. 1995; 38(3).
See All (38 Total) >
Books and Book Chapters:
  • Weinstock AL, Hartley-McAndrew M. West Syndrome/Infantile Spasms. 2009.
  • Weinstock A. Seizures and Epilepsy. 1999.
  • Weinstock AL. Seizures in Patients with Brain Tumors and Cancer.. 1999.

Professional Memberships:
  • National Association of Epilepsy Center (2009)
  • American Epilepsy Society (1997)
  • American Academy of Neurology (1994)
  • Child Neurology Society (1994)
Presentations:
  • "Laser Therapy for Epilepsy Surgery" Epilepsy Association, Milenium Hotel, Epilepsy Association (2014)
  • "Management and Challenges of Refractory Epilepsy" Invited Grand Rounds (CME) at WCA Hospital, WCA Hospital, Invited Grand Rounds (CME), WCA Hospital (2013)
  • "Imaging in Epilepsy" Imaging Symposium for Nurses and Imaging Technicians at Millard Fillmore Hospital, Millard Fillmore Hospital, Imaging Symposium for Nurses and Imaging Technicians (2011)
  • "Management of Refractory Pediatric Epilepsy" Invited Grand Rounds (CME): Schneider Children Hospital, Israel, Schneider Children Hospital (2008)
  • "Concepts in Refractory Epilepsy - Slockum-Dickson Teaching Day" Slockum-Dickson Teaching Day - CME Symposium, CME Symposium (2007)
  • "Management of Refractory Epilepsy" Invited Grand Round (CME)-Michigan State University, Michigan State University (2006)
  • "Catastrophic Epilepsy in Childhood" CME Symposium on Advances in Epilepsy, Marriott Hotel (2006)
  • "Management of Pediatric Epilepsy, Correlative Neuro-Anatomy Nursing Symposium" Nursing Symposium - Marriott Hotel, Marriott Hotel, Neurology (2004)
  • "Epilepsy Surgery" Neurology/ & Neurosurgery Grand Rounds - SUNY, Buffalo General Hospital, SUNY, Buffalo General Hospital, Neurology (2004)
  • "Management of Intractable Epilepsy" Sister's Hospital, Sister’s Hospital (2003)
  • "Management of Intractable Epilepsy" Olean General Hospital, Olean General Hospital, Neurology (2003)
  • "Epilepsy Surgery" Neurology/ & Neurosurgery Grand Rounds - SUNY, Buffalo General Hospital, SUNY, Buffalo General Hospital, Neurology (2002)
  • "Evaluation for Epilepsy Surgery" Neurosurgery Grand Rounds, Millard Fillmore Hospital, Neurology (2001)
  • "Video-EEG Monitoring" CME Symposium on Advances in Epilepsy - UB Center for the Arts, UB Center for the Arts, Neurology (2000)
  • "Towards a Neonatal EEG Classification" Epilepsy Grand Rounds at the Cleveland Clinic Foundation, The Cleveland Clinic Foundation, Neurology (1998)
See All (15 Total) >
Service Activities:
  • Grant Reviewer SUNY Brain Network of Excellence; Grant Reviewer, SUNY Brain Network of Excellence; Reviewer (2014)
  • Child Neurology, New York State Office of Medical Complaints and Physician Malpractice; Consultant (2012)
  • Representative on the Faculty Council to the School of Medicine and Biomedical Sciences; Representative on the Faculty Council to the School of Medicine and Biomedical Sciences at the State University of NY; School Representative (2009–2011)
  • Peer Reviewer for Epilepsia, Seizure, and Developmental Medicine & Child Neurology; Peer Reviewer for Epilepsia, Seizure, and Developmental Medicine & Child Neurology; Reviewer

Clinical Specialties:
Clinical Offices:
Insurance Accepted:

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Contact Information

Women & Childrens Hospital of Buffalo
Buffalo, NY 14222
Phone: (716) 878-7840
Fax: 716-878-7326
Email: alw4@buffalo.edu

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