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Barbara                        Bambach

Barbara J. Bambach MD

Department of Pediatrics

Clinical Associate Professor

Specialty/Research Focus

Pediatric Hematology-Oncology; Pediatrics

 
Professional Summary:

As a pediatric hematologist-oncologist, I care for children from birth through age 21 who have blood disorders or cancers. This includes care for children with illnesses such as anemia, platelet problems, white blood cell abnormalities, bleeding disorders, leukemias, lymphomas, kidney and liver tumors and other cancers. I diagnose these illnesses and develop treatment plans, often in collaboration with physicians from other specialties such as surgery and radiation oncology. I manage patients who are receiving care at the Women and Children’s Hospital of Buffalo and at Roswell Park Cancer Institute (RPCI).

In addition, I have a special focus on pediatric blood and marrow transplantation. I transplant children with malignant and non-malignant disorders, performing both autologous (self) and allogeneic (donor other than the patient) transplants.

My research is clinical in nature. I participate in clinical trials through the Children’s Oncology Group, the world’s largest organization devoted exclusively to childhood and adolescent cancer research. I also am the local principal investigator on several pediatric transplant trials through the Pediatric Blood and Marrow Transplant Consortium, the Blood and Marrow Transplant Clinical Trials Network and other multi-institutional trials.

I am the clinical director of the Pediatric Blood and Marrow Transplant Program located at RPCI. I have also served as the chair of the Institutional Review Board at the institute for over a decade.

I am extensively involved with medical education, providing lectures on pediatric hematology and oncology on a regular basis to University at Buffalo third-year medical students and pediatric residents and fellows.

Education and Training:
  • Fellowship, Pediatric Hematology/Oncology, Johns Hopkins University (1995)
  • Residency, Pediatrics, Children‘s National Medical Center (1992)
  • Internship, Pediatrics, Children‘s National Medical Center (1990)
  • MD, Medicine, University at Buffalo (1989)
  • BS, Biochemistry, University at Buffalo, magna cum laude (1985)
Employment:
  • Associate Professor, Pediatric Oncology, Roswell Park Cancer Institute (2011-present)
  • Co-Director, FACTS, Roswell Park Cancer Institute Transplant Program (2008-present)
  • Clinical Associate Professor, Pediatrics, University at Buffalo (2005-present)
  • Clinical Adjunct Faculty, Rochester Institute of Technology Physician Assistant Program, College of Health Sciences and Technology (1997-present)
  • Clinical Director, Pediatric Bone Marrow Transplant Program, Roswell Park Cancer Institute (1995-present)
  • Assistant Attending Physician, Division of Hematology/Oncology, UBMD Pediatrics, Women and Children‘s Hospital of Buffalo (1995-present)
  • Assistant Professor, Pediatric Oncology, Roswell Park Cancer Insititute (1995–2011)
  • Assistant Professor, Pediatrics, University at Buffalo (1995–2005)
  • Supervising Physician, Pediatric Emergency Department, Sinai Hospital of Baltimore (1993–1995)
Awards and Honors:
  • American Society of Pediatric Hematology/Oncology: Young Investigator Award (1995)
  • American Cancer Society: Clinical Oncology Fellowship (1992)
  • Alpha Epsilon Delta Premedical Honor Society
  • Alpha Omega Alpha Honor Medical Society
  • Castle Connolly Medical Ltd: America‘s Top Doctors (2016-2017)

Research Expertise:
  • Pediatric blood and marrow transplantation
Grants and Sponsored Research:
  • June 2007–May 2008
    Rational Design of Immunogens for Treatment of Neuroblastoma
    Association for Research of Childhood Cancer (AROCC)
    Role: Contributor
    $30,000

Journal Articles:
See all (7 more)
Books and Book Chapters:
  • Bambach BJ, Pohl H, Dome JS. "Uncommon Pediatric Genitourinary Tumors". Textbook of Uncommon Cancer, Fourth Edition. 2012.
  • Bambach BJ. "Hematopoietic Stem Cell Transplantation". Pediatric Critical Care, Fourth Edition. 2011.
  • Patel R, Bambach BJ. "12J - Graft vs. Host Disease". The NASPGHAN Fellows Concise Review of Pediatric Gastronenterology, Hepatology and Nutrition. 2011.
  • Bambach BJ. "Uncommon Pediatric Genitourinary Tumors". Textbook of Uncommon Cancer, Third Edition. 2006.
  • Bambach BJ. "Stem Cell Transplantation". Pediatric Critical Care, Third Edition. 2000.
  • Bambach BJ. "Uncommon Pediatric Genitourinary Tumors". Textbook of Uncommon Cancer, Second Edition. 1999.
  • Bambach BJ, Brecher M. "Pediatric Soft Tissue Sarcomas". Problems in General Surgery. 1999; 16(3).
Abstracts:
  • Ali L, Bambach BJ, Kozielski R, Wagner H, Lele SB, Mhawech-Fauceglia P. Ovarian Yolk Sac Tumor Associated with Major Fibrosarcoma Component in a 13-Year Old Girl. Int J Gynecol Pathol. 2010; 29(3).
  • Gil M, Bieniasz M, Wierzbicki A, Bambach BJ, Rokita H, Kozbor D. Targeting a Mimotope Vaccine to Activating Fcgamma Receptors Empowers Dendritic Cells to Prime Specific CD8+ T Cell Responses to Tumor-bearing Mice. J Immunol. 2009.
  • Hahn T, Roy HN, Cooper M, Paplham P, Alam A, Baer MR, Bambach BJ, Chanan-Khan AA, Czuczman MS, Wetzler M, Segal BH, McCarthy PL. Oral Beclomethasone Dipropionate for Treatment of Steroid-Refractory Acute or Chronic Gastrointestinal Graft-versus-Host Disease After Blood or Marrow Transplantation (BMT). Blood. 2003; 102.
  • Hahn T, Benekli M, Wong C, Moysich K, Hyland A, Michalek AM, Alam A, Baer MR, Bernstein ZP, Bambach BJ, Chanan-Khan AA, Czuczman MS, Wetzler M, McCarthy PL. A Prognostic Model for Prolonged Event-Free Survival After Autologous or Allogenic Blood or Marrow Transplantation for Relapsed and Refractory Hodgkin's Disease. Blood. 2003; 102.
  • Alam A, Varma H, Hahn T, Segal BH, Paplham P, Becker JL, Baer MR, Bambach BJ, Silva J, Slack JL, Wetzler M, McCarthy PL. Infectious Complications in Long-Term Survivors of Cord Blood Stem Cell Transplantation (CBSCT): Experience at Roswell Park Cancer Institute. Blood. 2002; 11.
  • Alam A, Lawrence D, Hahn T, Ford L, Dascomb S, Bambach BJ, Baer MR, Bernstein S, Bernstein ZP, Czuczman MS, Chanan-Khan AA, Slack JL, Wetzler M, Proulx G, McCarthy PL. Thrombotic Thrombocytopenic Purpura (TTP) in Allogenic Bone Marrow Transplant (Allo BMT) Risk Factors and Effect on Outcome: An Update on the Experience at RPCI. Blood. 2001; 11.
  • Jupudy V, Shaukat A, Hahn T, Rondeau C, Miller A, Alam A, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Mookerjee BK, Proulx G, McCarthy PL. Comparison of High Intensity versus Low Intensity Conditioning Regimens on Renal Toxicity in Allogenic Blood or Marrow Transplant (Allo BMT) Patients. Blood. 2001; 11.
  • Benekli M, Hahn T, Hernandez L, Miller A, Alam A, Baer MR, Bambach BJ, Bernstein S, Bernstein ZP, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Becker JL, Stewart C, McCarthy PL. Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mobilized Donor Bone Marrow (BM) Stem Cells Along with GM-CSF Administration Post Allogenic Bone Marrow Transplantation (ABMT) to Reduce the Incidence of Graft-versus-Host Disease (GVHD): Phase I. Blood. 2001; 11.
  • Alam A, Ahuja N, Hahn T, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, McCarthy PL. Fludarabine/Melphalan (Flu/Mel) Conditioning Regimen for Allogenic Blood or Marrow Transplantation (Allo BMT) in Patients Undergoing Second Transplantation. Blood. 2001; 11.
  • Hahn T, Alam A, Miller A, Meteer J, Dascomb S, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Becker JL, Stewart C, McCarthy PL. Use of Donor Lymphocyte Infusions (DLI) for Treatment of Relapse After Allogenic Bone Marrow Transplantation (AMBT): Effective GVT in Chronic Myeloid Leukemia (CML) with No Clinical GVHD. Blood. 2001; 11.
  • McCarthy PL, Hahn T, Cooper M, Brady A, Miller A, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Slack JL, Wetzler M, Herzig G, Stewart C. Analysis of OKT3 for Acute Graft-versus-Host Disease (GVHD) Prophylaxis in Allogeneic Bone Marrow Transplant (BMT) Patients. Blood. 2000; 96.
  • Simon M, Hahn T, Ford LA, Anderson B, Swinnich D, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Slack JL, Wetzler M, Herzig G, Schriber J, McCarthy PL. Possible Benefit of Low Molecular Weight Heparin (LMWH) for Hepatic VOD Prophylaxis After BMT. Blood. 2000; 96.
  • Wetzler M, Baer MR, Slack JL, Ford L, McCarthy PL, Bambach BJ. Umbilical Cord Blood Transplantation (UCBT) for Adult Chronic Myeloid Leukemia (CML) Patients - A Single Institution Experience. Blood. 2000; 96.
  • Laughlin MJ, Barker J, Bambach BJ, Koc ON, Rizzieri DA, Wagner JE, Gereson SL, Lazarus HM, Cairo M, Stevens CE, Rubinstein P, Kurtzberg J. Hematopoietic Engraftment and Survival After Unrelated Donor Umbilical Cord Blood (UCB) Transplantation in Adult Recipients. Blood. 2000; 96.
  • Alan A, Ford L, Nagubandi M, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Huang W, Slack JL, Wetzler M, Milk B, McCarthy PL. Treatment of Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome (TTP/HUS) Associated with Allogenic BMT: Lack of Impact on Final Outcome. Blood. 1998; 92(Sup 1).
  • Hahn T, Nagubandi M, Ford L, Milk B, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Slack JL, Wetzler M, Lipman B, McCarthy PL. Seasonal Variation in Adenovirus Infections in Blood and Marrow Transplant (BMT) Patients. Blood. 1998; 92(Sup 1).
  • Bambach BJ, Moser H, Blakemore K, Jones R. In Utero Bone Marrow Transplantation for Leukodystrophies Using CD34 Selection of Donor Marrow. Proc Amer Soc Pediatr Hematol Oncol. 1995.
See all (7 more)

Professional Memberships:
  • American Academy of Pediatrics
  • Children‘s Oncology Group
  • American Society of Hematology
  • American Society of Pediatric Hematology/Oncology
  • Pediatric Blood and Bone Marrow Consortium
Presentations:
  • "The Impact of a Wish" Pediatric Grand Rounds, Women and Children's Hospital of Buffalo (2016)
  • "Appearance Changes in Pediatric Patients" Marketing Department Cancer Talk Blog, Roswell Park Cancer Institute (2016)
  • "Update on Pediatric Bone Marrow Transplant" Quarterly Medical Staff Meeting, Women and Children‘s Hospital of Buffalo (2011)
  • "In Utero Bone Marrow Transplantation for Globoid Cell Leukodystrophy - The Hopkins Experience" 4th Annual Workshop on Krabbe‘s Disease, Hunter‘s Hope Foundation (2011)
  • "Hematopoietic Stem Cell Transplantation" Pediatric Intensive Care Unit Meeting, Women and Children‘s Hospital of Buffalo (2010)
  • "Atypical Presentation of Vaginal GvHD with Multiple Abnormal Pain Crisis" Annual Meeting, American Society for Blood and Marrow Transplantation (ASBMT) (2010)
  • "HSCT and GVHD" Pediatric GI Multi-Disciplinary Conference, Women and Children‘s Hospital of Buffalo (2010)
  • "And the Answer is..." Pediatric Grand Rounds, Women and Children‘s Hospital of Buffalo (2007)
  • "Immune Thrombocytopenic Purpura in Children" OB/GYN Grand Rounds, Women and Children‘s Hospital of Buffalo (2005)
  • "Pediatric Acute Lymphoblastic Leukemia" Pediatric Grand Rounds, Sisters of Charity Hospital (2005)
  • "Overview of Pediatric Malignancies" Western New York Oncology Nursing Society Education Days, Oncology Nursing Society (2004)
  • "Pediatric Malignancies" Western New York Oncology Nursing Society Meeting, Oncology Nursing Society (2004)
  • "Chemotherapy Principles and Agents in Pediatric Oncology" Pediatric Surgery Grand Rounds, Women and Children‘s Hospital of Buffalo (2003)
  • "Bone Marrow Transplantation" Cancer in the Classroom Conference, Roswell Park Cancer Institute (2003)
  • "Pediatric Non-Rhabdomyosarcomas" Surgical Oncology Core Curriculum Lecture Grand Rounds, Roswell Park Cancer Institute (2001)
  • "Analysis of OKT3 for Acute Graft-versus-Host Disease (GVHD) Prophylaxis in Allogeneic Bone Marrow Transplant (BMT) Patients" Annual Meeting, American Society of Hematology (2000)
  • "Hematopoietic Engraftment and Survival After Unrelated Donor Umbilical Cord Blood (UCB) Transplantation in Adult Recipients" Annual Meeting, American Society of Hematology (2000)
  • "Possible Benefit of Low Molecular Weight Heparin (LMWH) for Hepatic VOD Prophylaxis After BMT" Annual Meeting, American Society of Hematology (2000)
  • "Umbilical Cord Blood Transplantation (UCBT) for Adult Chronic Myeloid Leukemia (CML) Patients - A Single Institution Experience" Annual Meeting, American Society of Hematology (2000)
  • "Bone Marrow Transplantation" Cancer in the Classroom Conference, Roswell Park Cancer Institute (2000)
  • "Treatment of Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome (TTP/HUS) Associated with Allogenic BMT: Lack of Impact on Final Outcome" Annual Meeting, American Society of Hematology (1998)
  • "In Utero Bone Marrow Transplantation for Leukodystrophies Using CD34 Selection of Donor Marrow" Annual Meeting, American Society of Pediatric Hematology/Oncology (1995)
See all (12 more)
Service Activities:
  • Make-A-Wish Foundation: Regional Wish Committee; Committee Member (2016–present)
  • Women and Children‘s Hospital of Buffalo: Medical Advisory Committee; Committee Member (2012–present)
  • Roswell Park Cancer Institute: Pediatric Bone Marrow Transplant Steering Committee; Chair (2008–present)
  • Roswell Park Cancer Institute: Clinical Research Services Advisory Committee; Committee Member (2008–present)
  • Women and Children‘s Hospital of Buffalo: Hematology/Oncology Center of Excellence Team; Committee Member (2006–present)
  • Women and Children‘s Hospital of Buffalo: Hematology/Oncology Center of Excellence Team; Chair (2006–present)
  • Roswell Park Cancer Institute: Pediatric Center, Multidisciplinary Ambulatory Service Center; Physician Leader (2001–2005)
  • Make-A-Wish Foundation of Western New York; Director (2001–present)
  • Roswell Park Cancer Institute: Nutritional Support Committee; Committee Member (2001–present)
  • Roswell Park Cancer Institute: Member Advisory Committee for Clinical Recruitments; Committee Member (2000)
  • Roswell Park Cancer Institute: Phase I/II Committee; Committee Member (1999–2000)
  • Roswell Park Cancer Institute: Institutional Review Board; Chair (1999–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Resident Recruitment Committee; Committee Member (1999–present)
  • Roswell Park Cancer Institute: Institutional Review Board; Board Member (1996–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Hematology/Oncology Fellowship Training Program; Teacher (1995–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Promotions and Tenure Committee; Committee Member (1995–present)
  • Women and Children‘s Hospital of Buffalo: Cancer Committee; Committee Member (1995–present)
  • Roswell Park Cancer Institute/Women and Children‘s Hospital of Buffalo: Attend on Hematology/Oncology Service; Teacher
  • Roswell Park Cancer Institute: Attend on Pediatric Bone Marrow Transplant Service; Teacher

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Contact Information

Roswell Park Cancer Institute
Department of Pediatrics
Elm and Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-2333
Fax: (716) 845-8003
Email: bambach@buffalo.edu

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