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Bobby                          Mathew

Bobby Mathew MD

Department of Pediatrics

Clinical Assistant Professor

Specialty/Research Focus

Neonatal-Perinatal Medicine; Neonatology; Pediatrics

 

Education and Training:
  • Fellowship, Neonatal-Perinatal Medicine, University at Buffalo (2006)
  • Residency, Pediatrics, University at Buffalo (2006)
  • Internship, Pediatrics, University at Buffalo (2004)
  • MBBS, Medicine/Surgery, University of Kerala (1995)
  • MD, Medicine, Government Medical College (1994)
Employment:
  • Clinical Assistant Professor, Pediatrics, University at Buffalo (2008-present)
  • Attending Physician, Division of Neonatology, UBMD Pediatrics, Women and Children‘s Hospital of Buffalo (2005-present)
  • Associate Fellowship Program Director, Division of Neonatal-Perinatal Medicine, University at Buffalo
  • Specialist Registrar, Pediatric Intensive Care, Birmingham Children's Hospital, United Kingdom (2003)
  • Specialist Registrar, Pediatric Rotation, South East Scotland Medical, Scotland (2001–2002)
  • Senior House Officer, Dewsbury and District Hospital, United Kingdom (2000)
  • Senior House Officer, Neonatology, City Hospital, United Kingdom (1999–2000)
  • Senior House Officer, Pediatrics, Newcastle General Hospital, United Kingdom (1999)
  • Senior House Officer, Pediatrics, Sunderland Royal Hospital, United Kingdom (1998–1999)
  • Senior House Officer, Pediatrics and Neonatology, South Cleveland Hospital, United Kingdom (1997–1998)
Awards and Honors:
  • Eastern Society for Pediatric Research: Young Investigator of the Year Finalist (2013)
  • Eastern Society for Pediatric Research: Young Investigator of the Year Finalist (2012)

Research Expertise:
  • Effect of natriuretic peptides on pulmonary vasculature
  • Electrolyte supplementation in infants with bronchopulmonary dysplasia
  • Neonatal resuscitation
  • Role of natriuretic peptides in the transition at birth
  • Surfactant release
  • Thermoregulation in preterm infants
  • Transient tachypnea of the newborn
Grants and Sponsored Research:
  • January 2013–December 2013
    Dual Pulse Oximetry for Early Identification of Persistent Pulmonary Hypertension of Newborn and Critical Congenital Heart Disease
    Wildermuth Foundation
    Role: Principal Investigator
    $25,000
  • January 2010–January 2011
    Study of Optimal Ventilation to Chest Compression Ratio in Resuscitation of Neonatal Piglets
    American Academy of Pediatrics
    Role: Principal Investigator
    $10,000

Journal Articles:
See all (7 more)
Abstracts:
  • Sambalingam D, Swartz DD, Mathew B, Gugino SF, Koenigsknecht C, Nair J, Wedgwood S, Steinhorn RH, Lakshminrusimha S. Effect of Early Initiation Inhaled Nitric Oxide (iNO) on Oxygenation and Oxidative Stress in PPHN. PAS Meeting Abstracts. 2012; 71(3842).
  • Nair J, Mathew B, Nayak SP, Gugino SF, Wedgwood S, Steinhorn RH, Lakshminrusimha S. Antenatal Betamethasone Decreases Hypoxic Pulmonary Vasoconstriction in Late Preterm Lambs Delivered by Elective C-Section. PAS Meeting Abstracts. 2012; 71(1160).
  • Lakshminrusimha S, Mathew B, Gugino SF, Koenigsknecht C, Steinhorn RH, Swartz DD. Perinatal Pulmonary Hemodynamics in Acute and Chronic Models of Persistent Pulmonary Hypertension of Newborn (PPHN). PAS Meeting Abstracts. 2012; 71(3842).
  • Lakshminrusimha S, Mathew B, Ma CX, Nair J, Gugino SF, Koenigsknecht C, Steinhorn RH, Swartz DD. Does Parenchymal Lung Disease Alter the Relationship Between PO2 and Pulmonary Vascular Resistance (PVR)?. PAS Meeting Abstracts. 2012; 71(3842).
  • Mathew B, Swartz DD, Gugino SF, Sambalingam D, Koenigsknecht C, Lakshminrusimha S. Gas Exchange at Different Compression to Ventilation Ratios During Neonatal Resuscitation. PAS Meeting Abstracts. 2012; 71(4525).
  • Nair J, Gugino SF, Mathew B, Carmen M, Swartz DD, Lakshminrusimha S. PRBC Transfusion Increases Mesenteric Vasoconstriction in Preterm Lambs. PAS Meeting Abstracts. 2012; 71(2860).
  • Mathew B, Swartz DD, Nair J, Gugino SF, Carmen MF, Nielsen LC, Lakshminrusimha S. Pre-Oxygenation with 100% Oxygen Does Not Impact Time to Asystole in Newborn Piglets. PAS Meeting Abstracts. 2012; 71(2855).
  • Bazacliu C, Carmen M, Mathew B, Ryan RM, Lakshminrusimha S, Swartz DD. Intrauterine Growth Restriction Decreases Airway Responsiveness to Methacholine in Female Rats. PAS Meeting Abstracts. 2010; 67(2720).
  • Bazacliu C, Carmen M, Mathew B, Ryan RM, Lakshminrusimha S, Swartz DD. Intrauterine Growth Restriction Alters Norepinephrine Response in Rat Aortas in a Developmental and Gender Specific Manner. PAS Meeting Abstracts. 2010; 67(4416).
  • Mathew B, Lakshminrusimha S, Ryan RM. Retrospective Study of Epinephrine Use in the Delivery Room Resuscitation of Infants Born <= 25 Weeks. PAS Meeting Abstracts. 2010; 67.
  • Savorgnan F, Swartz DD, Mathew B, Wynn KA, Ryan RM, Lakshminrusimha S. Pulmonary Hemodynamics in Asphyxiated Lambs Resuscitated with 21% and 100% Oxygen. PAS Meeting Abstracts. 2010; 67(3713).
  • Nair J, Mathew B, Carmen M, Russell JA, Lakshminrusimha S. Norepinephrine Induced Ovine Mesenteric Artery Constriction Peaks in Late Preterm Gestation: Implications in Pathogenesis of Necrotizing Enterocolitis. PAS Meeting Abstracts. 2010; 67(4421).
  • Lakshminrusimha S, Mathew B, Russell JA, Wynn KA, Ryan RM, Nair J, Swartz DD. Pulmonary Vascular Resistance (PVR) Response to Oxygen is Altered by Inhaled Nitric Oxide (iNO) in Lambs with PPHN. PAS Meeting Abstracts. 2010; 67(3294).
  • Lakshminrusimha S, Mathew B, Wynn KA, Nair J, Ryan RM, Russell JA, Swartz DD. Inhaled Nitric Oxide (iNO) Prevents Hypoxic Pulmonary Vasoconstriction in Lambs with Persistent Pulmonary Hypertension of the Newborn (PPHN). Am J Respir Crit Care Med. 2010; 181.
  • Swartz DD, Russell JA, Bazacliu C, Carmen M, Mathew B, Ryan RM, Lakshminrusimha S. Intrauterine Growth Restriction Abolishes Airway Hyperresponsiveness to Methacholine in Female Rats. Am J Respir Crit Care Med. 2010; 181.
  • Mathew B, Russell JA, Steinhorn RH, Gugino SF, Nielsen LC, Ryan RM, Lakshminrusimha S. B-type Natriuretic Peptide (BNP) System in an Ovine Model of Persistent Pulmonary Hypertension of the Newborn (PPHN). PAS Meeting Abstracts. 2006; 59(3875).
  • Lakshminrusimha S, Morin FC, Steinhorn RH, Swartz DD, Ryan RM, Gugino SF, Mathew B, Wynn KA, Russell JA. Neonatal Resuscitation in Lambs with 100% O2 Decreases Pulmonary Vasodilator Response to Inhaled Nitric Oxide (NO) and Acetylcholine (ACh). PAS Meeting Abstracts. 2006; 59(4365).
  • Lakshminrusimha S, Gugino SF, Russell JA, Mathew B, Kumar V, Ryan RM, Morin FC. Pulmonary Arterial Vasoreactivity is Decreased by the Adjacent Bronchus in Juvenile Lambs. Proc AmThor Soc. 2005; 2.
  • Mathew B, Ryan RM, Gugino SF, Russell JA, Morin FC, Nielsen LC, Lakshminrusimha S. Activation of Natriuretic Peptide Receptor C Inhibits Adenylate Cyclase Mediated Relaxation in Juvenile Ovine Pulmonary Arteries (PA). PAS Meeting Abstracts. 2005; 57.
  • Gugino SF, Morin FC, Russell JA, Mathew B, Ryan RM, Lakshminrusimha S. Bronchial Epithelium Derived Relaxing Factor is More Effective on the Adventitial Side than Luminal Side of Pulmonary Artery (PA). PAS Meeting Abstracts. 2005; 57.
  • Lakshminrusimha S, Gugino SF, Mathew B, Swartz DD, Russell JA, Wynn KA, Morin FC, Davis JM, Steinhorn RH. Recombinant Human Superoxide Dismutase Improves Oxygenation Similar to Inhaled Nitric Oxide in Ovine Ductal Ligation Model of Persistent Pulmonary Hypertension of Newborn (PPHN). PAS Meeting Abstracts. 2005; 57.
  • Lakshminrusimha S, Gugino SF, Mathew B, Nielsen LC, Goldsby TS, Morin FC, Davis JM, Russell JA, Steinhorn RH. Intratracheal Recombinant Human Superoxide Dismutase (IT-rhSOD) Prevents Increased Pulmonary Arterial Contractility Following Ventilation with 100% O2 in Neonatal Control and Persistent Pulmonary Hypertension (PPHN) Lambs. PAS Meeting Abstracts. 2005; 57.
  • Mathew B, Ryan RM, Gugino SF, Russell JA, Morin FC, Nielsen LC, Lakshminrusimha S. Natriuretic Peptide Receptor-Type C Distribution and Function in Juvenile Ovine Pulmonary Arteries. Proc Am Thor Soc. 2005; 2.
  • Mathew B, D'Angelis CA, Swartz DD, Kumar V, Nickerson PA, Wang H, Wynn KA, Holm BA, Ryan RM. Natriuretic Peptide Clearance Receptor is Down Regulated in the Pulmonary Epithelium After Birth in Preterm and Full Term Lambs. Pediatr Res. 2004; 255(4).
See all (14 more)
Books and Book Chapters:
  • Mathew B, Lakshminrusimha S. "Non Invasive Assessment of Gas Exchange in the NICU". Assisted Ventilation of the Neonatate, 6th Edition. 2016.
  • Mathew B, Lakshminrusimha S. "Persistent Pulmonary Hypertension of the Newborn and Hypoxemic Respiratory Failure". Workbook of Practical Neonatology, 5th Edition. 2015.
  • Mathew B, Lakshminrusimha S. "Inhaled Nitric Oxide in the Newborn". Clinical Care Paths in Neonatology..

Professional Memberships:
  • American Academy of Pediatrics
Presentations:
  • "Continuous Capnography Monitoring during Resuscitation in Neonatal Ashpyxial Cardiac Arrest" Annual Meeting, Pediatric Academic Societies (2016)
  • "Does NIRS Regional Saturation (rSO2) Correlate with Tissue Oxygen Delivery?" Annual Meeting, Pediatric Academic Societies (2016)
  • "Continuous Capnography (End Tidal CO2) Monitoring During Neonatal Resuscitation" Annual Meeting, Pediatric Academic Societies (2015)
  • "Optimal Target Oxygen Saturation (SpO2) in Term Lambs with Meconium Aspiration Syndrome (MAS) and Persistent Pulmonary Hypertension of the Newborn (PPHN)" Annual Meeting, Pediatric Academic Societies (2015)
  • "Continuous Capnography (End Tidal CO2) Monitoring During Neonatal Resuscitation" Annual Conference, Eastern Society for Pediatric Research (2015)
  • "Optimal Target Oxygen Saturation (SpO2) in Term Lambs with Meconium Aspiration Syndrome (MAS) and Persistent Pulmonary Hypertension of the Newborn (PPHN)" Annual Conference, Eastern Society for Pediatric Research (2015)
  • "Clinical and Red Blood Cell Parameters of Acute and Chronic Feto-Maternal Hemorrhage" Annual Conference, American Academy of Pediatrics (2014)
  • "Oxygen Saturation Index and Severity of Hypoxic Respiratory Failure" Neonatal Cardiopulmonary Biology Young Investigator's Forum (2014)
  • "Hemodynamic and Respiratory Variables with Resuscitation Adhering to Oxygen Saturation Guidelines from Neonatal Resuscitation Program (NRP)" Annual Meeting, Pediatric Academic Societies (2014)
  • "Is Oxygen Saturation Index (OSI) a Valid Indicator of Neonatal Hypoxemic Respiratory Failure?" Annual Meeting, Pediatric Academic Societies (2014)
  • "Is Pulse Oximetry Screening for Critical Congenital Heart Disease (CCHD) Effective in the NICU?" Annual Meeting, Pediatric Academic Societies (2014)
  • "Norepinephrine is a More Selective Systemic Vasoconstrictor Compared to Dopamine in Preterm Lambs" Annual Meeting, Pediatric Academic Societies (2014)
  • "Oxygenation Indices and Correlation with Pulmonary Vascular Resistance" Annual Meeting, Pediatric Academic Societies (2014)
  • "Pharmacological Factors and Risk of Spontaneous Intestinal Perforation (SIP)" Annual Meeting, Pediatric Academic Societies (2014)
  • "Rescuscitator's Perceptions and Time for Corrective Ventilation Steps during Simulated Neonatal Resuscitation" Annual Meeting, Pediatric Academic Societies (2014)
  • "Significance of Apnea at Birth Following Cesarean Section Under General Anesthesia" Annual Meeting, Pediatric Academic Societies (2014)
  • "Hemodynamic and Respiratory Variables with Resuscitation Adhering to Oxygen Saturation Guidelines from Neonatal Resuscitation Program (NRP)" Annual Conference, Eastern Society for Pediatric Research (2014)
  • "Is Oxygen Saturation Index (OSI) a Valid Indicator of Neonatal Hypoxemic Respiratory Failure?" Annual Conference, Eastern Society for Pediatric Research (2014)
  • "Norepinephrine is a More Selective Systemic Vasoconstrictor Compared to Dopamine in Preterm Lambs" Annual Conference, Eastern Society for Pediatric Research (2014)
  • "Oxygenation Indices and Correlation with Pulmonary Vascular Resistance" Annual Conference, Eastern Society for Pediatric Research (2014)
  • "Pharmacological Factors and Risk of Spontaneous Intestinal Perforation (SIP)" Annual Conference, Eastern Society for Pediatric Research (2014)
  • "Significance of Apnea at Birth Following Cesarean Section Under General Anesthesia" Annual Conference, Eastern Society for Pediatric Research (2014)
  • "Optimal Heart Rate Cut Off for Initiation of Chest Compressions during Neonatal Resuscitation" Annual Meeting, Pediatric Academic Societies (2013)
  • "Gas Exchange at Different Compression to Ventilation Ratios During Neonatal Resuscitation" Annual Meeting, Pediatric Academic Societies, Neonatology - General (2012)
  • "Antenatal Betamethasone Decreases Hypoxic Pulmonary Vasoconstriction in Late Preterm Lambs Delivered by Elective C-Section" Annual Meeting, Pediatric Academic Societies, Neonatal Pulmonology Vascular Biology (2012)
  • "Does Parenchymal Lung Disease Alter the Relationship Between PO2 and Pulmonary Vascular Resistance (PVR)?" Annual Meeting, Pediatric Academic Societies, Neonatal Pulmonology (2012)
  • "Effect of Early Initiation Inhaled Nitric Oxide (iNO) on Oxygenation and Oxidative Stress in PPHN" Annual Meeting, Pediatric Academic Societies, Neonatal Pulmonology (2012)
  • "Perinatal Pulmonary Hemodynamics in Acute and Chronic Models of Persistent Pulmonary Hypertension of Newborn (PPHN)" Annual Meeting, Pediatric Academic Societies, Neonatal Pulmonology (2012)
  • "PRBC Transfusion Increases Mesenteric Vasoconstriction in Preterm Lambs" Annual Meeting, Pediatric Academic Societies, Neonatal Fetal Nutrition and Metabolism II (2012)
  • "Pre-Oxygenation with 100% Oxygen Does Not Impact Time to Asystole in Newborn Piglets" Annual Meeting, Pediatric Academic Societies, Neonatal-Patient Oriented Research: Resuscitation (2012)
  • "Antenatal Betamethasone Decreases Hypoxic Pulmonary Vasoconstriction in Late Preterm Lambs Delivered by Elective C-Section" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "Does Parenchymal Lung Disease Alter the Relationship Between PO2 and Pulmonary Vascular Resistance (PVR)?" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "Effect of Early Initiation Inhaled Nitric Oxide (iNO) on Oxygenation and Oxidative Stress in PPHN" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "Gas Exchange at Different Compression to Ventilation Ratios During Neonatal Resuscitation" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "Perinatal Pulmonary Hemodynamics in Acute and Chronic Models of Persistent Pulmonary Hypertension of Newborn (PPHN)" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "PRBC Transfusion Increases Mesenteric Vasoconstriction in Preterm Lambs" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "Pre-Oxygenation with 100% Oxygen Does Not Impact Time to Asystole in Newborn Piglets" Annual Conference, Eastern Society for Pediatric Research (2012)
  • "Antenatal Betamethasone Improves Pulmonary Transition in Late Preterm Lambs Delivered by Elective Cesarean Section" Annual Meeting, Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Effect of FiO2 and NO on Oxygenation and Pulmonary Vascular Resistance at Birth" Annual Meeting, Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Effect of Inspired Oxygen and Inhaled Nitric Oxide (iNO) on Oxygen Uptake from the Lung and Arterial Oxygen Content in Newborn Lambs and Lambs with Persistent Pulmonary Hypertension of the Newborn (PPHN)" Annual Meeting, Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Enteral Feeding and Antenatal Betamethasone Alter Mesenteric Vascular Reactivity in Late Preterm Lambs" Annual Meeting, Pediatric Academic Societies (2011)
  • "Gas Exchange in the First Minute of CPR Following Asphyxial Cardiac Arrest in Newborn Piglets" Annual Meeting, Pediatric Academic Societies (2011)
  • "Location of Spontaneous Intestinal Perforation (SIP) - Role of Initial Peristalsis" Annual Meeting, Pediatric Academic Societies (2011)
  • "Superoxide Anions Mediate Increased Pulmonary Arterial Contractility in 100% O2 Resuscitated Asphyxiated Lambs" Annual Meeting, Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Intrauterine Growth Restriction Alters Vascular Reactivity in Adult Female Rats" Annual Meeting, Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Effect of Inspired Oxygen and Inhaled Nitric Oxide (iNO) on Oxygen Uptake from the Lung and Arterial Oxygen Content in Newborn Lambs and Lambs with Persistent Pulmonary Hypertension of the Newborn (PPHN)" Annual Conference, Eastern Society for Pediatric Research (2011)
  • "Enteral Feeding and Antenatal Betamethasone Alter Mesenteric Vascular Reactivity in Late Preterm Lambs" Annual Conference, Eastern Society for Pediatric Research (2011)
  • "Gas Exchange in the First Minute of CPR Following Asphyxial Cardiac Arrest in Newborn Piglets" Annual Conference, Eastern Society for Pediatric Research (2011)
  • "Location of Spontaneous Intestinal Perforation (SIP) - Role of Initial Peristalsis" Annual Conference, Eastern Society for Pediatric Research (2011)
  • "Norepinephrine Induced Ovine Mesenteric Artery Constriction Peaks in Late Preterm Gestation: Implications in Pathogenesis of Necrotizing Enterocolitis" Annual Meeting, Pediatric Academic Societies (2010)
  • "Norepinephrine Induced Ovine Mesenteric Artery Constriction Peaks in Late Preterm Gestation: Implications in Pathogenesis of Necrotizing Enterocolitis" Annual Conference, Eastern Society for Pediatric Research (2010)
  • "A Single Center Retrospective Study of Risk Factors for Spontaneous Intestinal Perforation in Neonates" Annual Meeting, Pediatric Academic Societies (2009)
  • "A Single Center Retrospective Study of Risk Factors for Spontaneous Intestinal Perforation (SIP) in Neonates" Annual Conference, Eastern Society for Pediatric Research (2009)
  • "Vinyl Bag vs. Thermal Mattress to Prevent Hypothermia in Extremely Low Birth Weight Infants" Annual Meeting, Pediatric Academic Societies, Neonatology (2008)
  • "Vinyl Bag vs. Thermal Mattress to Prevent Hypothermia in Extremely Low Birth Weight Infants" Annual Conference, Eastern Society for Pediatric Research (2008)
  • "B-type Natriuretic Peptide (BNP) System in an Ovine Model of Persistent Pulmonary Hypertension of the Newborn (PPHN)" Annual Meeting, Pediatric Academic Societies (2006)
  • "Neonatal Resuscitation in Lambs with 100% O2 Decreases Pulmonary Vasodilator Response to Inhaled Nitric Oxide (NO) and Acetylcholine (ACh)" Annual Meeting, Pediatric Academic Societies (2006)
  • "B-type Natriuretic Peptide System in an Ovine Model of Persistent Pulmonary Hypertension of the Newborn" Annual Conference, Eastern Society for Pediatric Research (2006)
  • "Activation of Natriuretic Peptide Receptor C Inhibits Adenylate Cyclase Mediated Relaxation in Juvenile Ovine Pulmonary Arteries (PA)" Annual Meeting, Pediatric Academic Societies, Vascular Mediators in Persistent Pulmonary Hypertension (2005)
  • "Bronchial Epithelium Derived Relaxing Factor is More Effective on the Adventitial Side than Luminal Side of Pulmonary Artery (PA)" Annual Meeting, Pediatric Academic Societies (2005)
  • "Intratracheal Recombinant Human Superoxide Dismutase (IT-rhSOD) Prevents Increased Pulmonary Arterial Contractility Following Ventilation with 100% O2 in Neonatal Control and Persistent Pulmonary Hypertension (PPHN) Lambs" Annual Meeting, Pediatric Academic Societies (2005)
  • "Natriuretic Peptide Receptor Type C Distribution and Function in Juvenile Ovine Pulmonary Arteries" Annual International Conference, American Thoracic Society (2005)
  • "Pulmonary Arterial Vasoreactivity is Decreased by the Adjacent Bronchus in Juvenile Lambs" International Conference, American Thoracic Society (2005)
  • "Recombinant Human Superoxide Dismutase Improves Oxygenation Similar to Inhaled Nitric Oxide in Ovine Ductal Ligation Model of Persistent Pulmonary Hypertension of Newborn (PPHN)" Annual Meeting, Pediatric Academic Societies, Pulmonary Vascular Biology Session (2005)
  • "Use of Vinyl Bags in the Delivery Room Prevents Hypothermia in Preterm Very Low Birth Weight Infants" Annual Meeting, Pediatric Academic Societies (2005)
  • "Natriuretic Peptide Receptor C in Perinatal Transition" New York Neonatology Thruway Conference (2004)
  • "Natriuretic Peptide Clearance Receptor is Downregulated Following Birth in Preterm and Term Lambs" Annual Meeting, Pediatric Academic Societies (2004)
  • "Natriuretic Peptide Clearance Receptor is Downregulated Following Birth in Preterm and Term Lambs" Annual Conference, Eastern Society for Pediatric Research (2004)
See all (58 more)

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Contact Information

Women and Children‘s Hospital of Buffalo
Division of Neonatology
219 Bryant Street
Buffalo, NY 14222
Phone: (716) 878-7673
Fax: (716) 878-7945
Email: bmathew2@buffalo.edu

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