Clare J. Twist MD, MS

Clare Twist

Clare J. Twist
MD, MS

Clinical Professor

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Pediatric Hematology-Oncology; Pediatrics

Contact Information
Roswell Park Cancer Institute
Department of Pediatrics
Elm and Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-2333
Fax: (716) 845-8003
ctwist@buffalo.edu


Patient Care

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Education and Training:

  • Fellowship, Pediatric Hematology/Oncology, Harvard Medical School (1993)
  • Fellowship, Pediatric Hematology/Oncology, Harvard Medical School (1991)
  • Residency, Pediatrics, Northwestern University (1990)
  • Internship, Pediatrics, Northwestern University (1988)
  • MD, Medicine, Albany Medical College (1987)
  • MS, Natural Sciences/Immunology, University at Buffalo/Roswell Park Memorial Institute (1984)
  • BS, University of Notre Dame (1982)

Employment:

  • Fellowship Program Director, Hematology/Oncology, Pediatrics, University at Buffalo (2018-present)
  • Professor, Oncology, Roswell Park Comprehensive Cancer Center (2016-present)
  • Clinical Professor, Pediatrics, University at Buffalo (2016-present)
  • Staff Physician, Pediatric Oncology, Roswell Park Comprehensive Cancer Center (2016-present)
  • Attending Physician, Hematology/Oncology, UBMD Pediatrics, Oishei Children‘s Hospital (2016-present)
  • Director, Pediatric Experimental Therapeutics, Roswell Park Comprehensive Cancer Center (2016-present)
  • Associate Professor, Pediatrics, Stanford University, School of Medicine (2008–2016)
  • Attending Physician, Pediatric Hematology/Oncology, Lucile Packard Children‘s Hospital (1999–2016)
  • Medical Director, Pediatric Oncology Unit, El Camino Hospital (2012–2014)
  • Assistant Professor, Pediatrics, Stanford University, School of Medicine (2000–2008)
  • Acting Assistant Professor, Pediatrics, Stanford University, School of Medicine (1999–2000)
  • Attending Physician, Bone Marrow Transplant Service, Brigham and Women's Hospital (1994–1999)
  • Associate Physician, Hematology/Oncology, Brigham and Women‘s Hospital (1994–1999)
  • Attending Physician, Bone Marrow Transplant Service, Boston Children's Hospital (1993–1999)
  • Assistant in Medicine, Boston Children's Hospital (1993–1999)
  • Instructor, Pediatrics, Harvard Medical School (1993–1999)
  • Staff Physician, Pediatric Oncology, Dana-Farber Cancer Institute (1990–1999)
  • Attending Physician, Pediatric Hematology, Boston Children‘s Hospital (1990–1999)
See all (8 more)

Awards and Honors:

  • Children's Memorial Hospital: Outstanding Resident Teaching Award (1990)
  • Albany Medical College: Lamb Foundation Prize (1987)
  • Albany Medical College: Senior Medical Student Special Award (1987)

Research Expertise:

  • Early Phase Clinical Trials in Children
  • Neuroblastoma

Journal Articles:

See all (22 more)

Books and Book Chapters:

  • Twist CJ, Tedder TF. "Structure of the Mouse HB15 Gene". Leukocyte Typing V: White Cell Differentiation Antigens, Vol. 1. 1995.
  • Pauly JL, Twist CJ, Ovak G, Russell C, Constantino J. "Thymic Hormones and Lymphokines ‘83". Spring Symposium. 1983.

Professional Memberships:

  • American Society of Pediatric Hematology/Oncology (2006–present)
  • American Society of Clinical Oncology (2002–present)
  • American Academy of Pediatrics (2001–2005)
  • Children's Oncology Group (2001–present)
  • American Society of Hematology (2001–present)
  • American Society for Blood and Marrow Transplantation (1995–1999)
  • Massachusetts Medical Society (1994–1996)
  • American Medical Student Association (1983–1987)

Presentations:

  • "Prospective Analysis of EBV+ PTLD in a Multi-Center Study of Pediatric Transplant Recipients" American Transplant Congress, American Society of Transplant Surgeons/American Society of Transplantation (2018)
  • "Anti-Cancer Therapies" Pediatric Grand Rounds, Oishei Children's Hospital (2018)
  • "Premature Physeal Closure After Prolonged Fenretinide Exposure" Annual Meeting, Advances in Neuroblastoma Research Association (2016)
  • "Validation of Image-Defined Risk Factor (IDRF) Assignment in Patients with Intermediate-Risk Neuroblastoma: A Report from the Children’s Oncology Group Study ANBL0531" Annual Meeting, Advances in Neuroblastoma Research Association (2016)
  • "Premature Physeal Closure After Prolonged Fenretinide Exposure" Annual Meeting, American Society of Pediatric Hematology/Oncology (2016)
  • "Cancer Recurrence and Mortality After Pediatric Heart Transplantation for Anthracycline Cardiomyopathy" Annual Meeting, International Society for Heart and Lung Transplantation (2016)
  • "Neuroblastoma: Therapeutic Successes and Future Challenges" Bass Center Grand Rounds, Stanford University School of Medicine (2016)
  • "Measuring Pediatric Hematology/Oncology Fellows' Skills in Humanism and Professionalism: A Novel Assessment Instrument" Annual Meeting, American Society of Pediatric Hematology/Oncology (2015)
  • "Trends in End-of-Life Care in Pediatric Hematology, Oncology, and Stem Cell Transplant Patients" Annual Meeting, American Society of Pediatric Hematology/Oncology (2015)
  • "Neuroblastoma" Pediatric Hematology/Oncology Fellowship Core Lecture Series, Stanford University School of Medicine (2015)
  • "Maintaining Outstanding Outcomes Using Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma: A Report from the Children‘s Oncology Group Study ANBL0531" Annual Meeting, American Society of Clinical Oncology (2014)
  • "Maintaining Outstanding Outcomes Using Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma: A Report from the Children's Oncology Group Study ANBL0531" Annual Meeting, Advances in Neuroblastoma Research Association (2014)
  • "Post-Transplant Lymphoproliferative Disorders" Pediatric Solid Organ Transplant Symposium, Lucile Packard Children's Hospital (2014)
  • "Pediatric Oncology Highlights of the Day" Annual Meeting, American Society of Clinical Oncology (2013)
  • "Maintenance of Certification Learning Session: Neuroblastoma" Annual Meeting, American Society of Pediatric Hematology/Oncology (2013)
  • "Morbidity and Mortality Risks in Infants with Stage 4S Neuroblastoma: A Report from the Children’s Oncology Group Study ANBL0531, 'Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma'" Annual Meeting, Advances in Neuroblastoma Research Association (2012)
  • "Outcome Analysis of Non-High-Risk Neuroblastoma Patients Enrolled on Children’s Oncology Group Trials P9641 and A3961" Annual Meeting, Advances in Neuroblastoma Research Association (2012)
  • "Outcome Analysis of Non-High-Risk Neuroblastoma Patients Enrolled on Children’s Oncology Group Trials P9641 and A3961" Annual Meeting, American Society of Clinical Oncology (2012)
  • "Pediatric Oncology Highlights of the Day" Annual Meeting, American Society of Clinical Oncology (2012)
  • "Neuroblastoma" Radiation Oncology Residency Core Curriculum Lecture, Stanford University School of Medicine (2012)
  • "Post-Transplant Lymphoproliferative Disorders" Pediatric Nephrology Continuing Medical Education Lecture, Lucile Packard Children's Hospital (2012)
  • "Post-Transplant Lymphoproliferative Disorder: Is There a Role for 18F FDG PET/CT?" Annual Meeting, Radiological Society of North America (2011)
  • "Treatment of Recurrent Post-Transplant Lymphoproliferative Disorder (PTLD) of the Central Nervous System (CNS) with High-Dose Methotrexate (HD-MTX)" XI International Small Bowel Transplant Symposium, Intestinal Rehabilitation and Transplant Association (2009)
  • "Neuroblastoma" Radiation Oncology Residency Core Curriculum Lecture, Stanford University School of Medicine (2009)
  • "Pediatric Hematology: Oncology as a Career Choice" Pediatric Lecture Series, Stanford University School of Medicine (2009)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture, Lucile Packard Children's Hospital (2009)
  • "Isolated Tumor Cells are Routinely Detected by Immunohistochemistry in Histologically Negative Bone Marrow Biopsies from Neuroblastoma Patients" Annual Meeting, Advances in Neuroblastoma Research Association (2008)
  • "Nuclear Medicine Imaging in Pediatric Malignancies" Nuclear Medicine Grand Rounds, Stanford University School of Medicine (2008)
  • "Oncologic Emergencies" Stanford/Kaiser Emergency Medicine Core Curriculum Lecture, Stanford University School of Medicine (2008)
  • "Pediatric Hematology: Oncology as a Career Choice" Pediatric Lecture Series, Stanford University School of Medicine (2008)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture, Lucile Packard Children's Hospital (2008)
  • "A Phase I Study of a Novel Human Monoclonal Antibody (mAb216) with Chemotherapy for the Treatment of Patients with Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemia" Annual Meeting, American Society of Hematology (2007)
  • "Retrospective Survey of Children Treated for Relapsed Acute Lymphoblastic Leukemia (Complete Remission (CR) Rates): A Report from the Therapeutic Advances in Childhood Leukemia (TACL) Consortium" Annual Meeting, American Society of Hematology (2007)
  • "Intermediate-Risk Neuroblastoma" Parent Conference, Children's Neuroblastoma Cancer Foundation (2007)
  • "Neuroblastoma Update" Pediatric Oncology Grand Rounds, University of Texas Southwestern (2007)
  • "Pediatric Hematology/Oncology as a Career Choice" Pediatric Lecture Series, Stanford University School of Medicine (2007)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture, Lucile Packard Children's Hospital (2007)
  • "Perinatal Neuroblastoma" Neonatology Lecture Series, Lucile Packard Children's Hospital (2007)
  • "Post-Transplant Lymphoproliferative Disorders" Radiation Oncology Residency Core Curriculum Lecture, Stanford University School of Medicine (2007)
  • "Treatment of Neuroblastoma: A Paradigm for Multidisciplinary Care" Leadership Forum, Lucile Packard Children's Hospital (2007)
  • "Mature Results of a Prospective Trial of Rituximab in Patients (pt) with Post-Transplant Lymphoproliferative Disorder (PTLD) Unresponsive or Ineligible for Reduced Immunosuppression (RIS)" Annual Meeting, American Society of Hematology (2006)
  • "A Phase I Clinical Trial of the Hu14.18-IL2 (EMD 273063) as a Treatment for Children with Refractory or Recurrent Neuroblastoma and Melanoma: A Study of the Children’s Oncology Group" Annual Meeting, Advances in Neuroblastoma Research Association (2006)
  • "Oncologic Emergencies" Stanford/Kaiser Emergency Medicine Core Curriculum Lecture, Stanford University School of Medicine (2006)
  • "Pediatric Hematology/Oncology as a Career Choice" Pediatric Lecture Series, Stanford University School of Medicine (2006)
  • "Pediatric Oncologic Emergencies" Continuing Medical Education Lecture Series, Watsonville Community Hospital Emergency Department (2006)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture, Lucile Packard Children's Hospital (2006)
  • "Neuroblastoma in a Patient with Noonan Syndrom: Possible Genotype/Phenotype Correlations in PTPN11" Annual Meeting, American Society of Human Genetics (2005)
  • "Impact of Body Composition on Pharmacokinetics of Doxorubicin in Pediatric Patients: A Glaser Pediatric Research Network Study" Annual Meeting, American Society of Clinical Oncology (2005)
  • "Low Stage Neuroblastoma" Parent Conference, Children's Neuroblastoma Cancer Foundation (2005)
  • "Pediatric Liver Tumors" Pediatric Liver Transplant Conference, Lucile Packard Children's Hospital (2005)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture, Lucile Packard Children's Hospital (2005)
  • "Wilms Tumor" Radiation Oncology Residency Core Curriculum Lecture, Stanford University School of Medicine (2005)
  • "Age Continues to be a Powerful Predictor of EFS and OS in Neuroblastoma" Annual Meeting, Advances in Neuroblastoma Research Association (2004)
  • "Neuroblastoma" Radiation Oncology Residency Core Curriculum Lecture, Stanford University School of Medicine (2004)
  • "Update on Neuroblastoma" Nuclear Medicine Grand Rounds, Stanford University School of Medicine (2004)
  • "Monoclonal Antibody 216 (MAb 216), a VH4-34 Encoded Antibody, is a Novel Cytotoxic Agent for B-Progenitor Acute Lymphoblastic Leukemia (ALL)" Annual Meeting, American Society of Hematology (2003)
  • "Interactive Encoding of Whole Body 123I-MIBG Images in the Evaluation of Patients with Neuroblastoma" 4th European Symposium on Paediatric Nuclear Medicine, European Association of Nuclear Medicine (2003)
  • "Oncologic Emergencies" Stanford/Kaiser Emergency Medicine Core Curriculum Lecture, Stanford University School of Medicine (2003)
  • "Update on Neuroblastoma" Nuclear Medicine Grand Rounds, Stanford University School of Medicine (2003)
  • "Post-Transplant Lymphoproliferative Disorders" Pediatric Infectious Disease Conference, Lucile Packard Children's Hospital (2002)
  • "Rituximab is Effective Therapy for Post-Transplant Lymphoproliferative Disorder (PTLD) Not Responding to Reduction in Immunosuppression: A Prospective Trial in Adults and Children" Annual Meeting, American Society of Clinical Oncology (2001)
  • "Neuroblastoma 2001" Pediatric Grand Rounds, Lucile Packard Children's Hospital (2001)
  • "New Treatments for Genetic Diseases" Annual Meeting, New England Regional Genetics Group (1998)
  • "Cytoxan and Total Body Irradiation Conditioning Results in Stable Donor Marrow Engraftment in Patients with Metabolic Storage Diseases Undergoing Allogeneic Bone Marrow Transplantation" Annual Meeting, American Society of Pediatric Hematology/Oncology (1997)
  • "Bone Marrow Transplantation for Metabolic Storage Diseases" Pediatric Oncology Grand Rounds, Dana-Farber Cancer Institute (1997)
  • "Bone Marrow Transplantation for Metabolic Storage Diseases" Bone Marrow Transplantation Conference, Harvard Medical School (1997)
  • "The Use of Defibrotide (DF) in BMT-Associated Veno-Occlusive Disease (VOD)" Annual Meeting, American Society of Clinical Oncology (1996)
  • "Structure of the Mouse CD83 Gene" Annual Meeting, American Society of Hematology (1995)
  • "Structure of the Mouse HB15 Gene" 5th International Workshop on Human Leukocyte Differentiation Antigens, Human Cell Differentiation Molecules (1993)
See all (59 more)

Service Activities:

  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology; Deputy Medical Editor (2017–present)
  • Cincinnati Children's Hospital: Data Safety and Monitoring Committee; Committee Member (2016–present)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology; Past Chair (2014–2015)
  • Lucile Packard Children's Hospital: Interns/Residents; Advisor (2013–2016)
  • Stanford University Cancer Center: Scientific Review Committee; Committee Member (2013–2016)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Clinical Competency Committee; Chair (2013–2016)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellow Trainee; Clinical Mentor (2013–2016)
  • American Society of Pediatric Hematology/Oncology: Certification and Continuing Education Committee; Committee Member (2013–2015)
  • American Society of Clinical Oncology: Clinical Cancer Advances Journal; Editorial Advisor (2013–present)
  • National Cancer Institute: PDQ Pediatric Treatment Editorial Advisory Board; Board Member (2013–present)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellowship Recruitment Committee; Committee Member (2012–2016)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellowship Scholarly Oversight Committee; Committee Member (2012–2016)
  • American Society of Pediatric Hematology/Oncology: Training Committee; Committee Member (2012–2015)
  • Lucile Packard Children's Hospital: Medical Executive Committee; Committee Member (2012–2015)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology; Chair (2012–2014)
  • National Heart, Lung, and Blood Institute: Taskforce on the Future of the Workforce in Hematology; Member (2012–2014)
  • American Society of Clinical Oncology 2013 Annual Meeting: Pediatric Oncology Education Program Committee; Committee Member (2012–2013)
  • American Society of Clinical Oncology 2013 Annual Meeting: Pediatric Oncology Scientific Program Committee; Track Leader (2012–2013)
  • Advances in Neuroblastoma Research Annual Meeting: Scientific Program Committee; Committee Member (2012)
  • Lucile Packard Children's Hospital: Tissue Committee; Committee Member (2011–2016)
  • American Society of Clinical Oncology 2012-2014 Annual Meetings: Pediatric Oncology Scientific Program Committee; Committee Member (2011–2014)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology Credentials Committee; Committee Member (2010–2014)
  • Lucile Packard Children's Hospital: Bass Center Process Improvement Committee; Committee Member (2010–2012)
  • Lucile Packard Children's Hospital: Pediatric Oncology Chemotherapy Error Prevention Committee; Committee Member (2010–2012)
  • New Approaches to Neuroblastoma Therapy Consortium: Scientific Review Committee; Committee Member (2010–2012)
  • Dana-Farber Cancer Institute: Claudia Adams Barr Program in Innovative Basic Cancer Research Presidential Scientific Advisory Council; Member (2010–present)
  • American Board of Pediatrics: Subspecialties Committee; Committee Member (2009–2014)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program; Faculty Mentor (2008–2016)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology; Board Member (2008–2013)
  • Pediatric Transplantation Journal; Ad Hoc Reviewer (2008–present)
  • Stanford University: Med Scholars Program; Faculty Mentor (2007–2009)
  • Stanford University School of Medicine: Pediatric Journal Club; Faculty Facilitator (2007–2008)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellowship Boot Camp Lecture Series; Lecturer (2006–2012)
  • Stanford University School of Medicine: Pediatric Lecture Series; Lecturer (2006–2010)
  • Children's Oncology Group: Neuroblastoma Steering Committee; Committee Member (2006–present)
  • Pediatric Blood and Cancer Journal; Ad Hoc Reviewer (2006–present)
  • Stanford University: Pediatric Residency Program - Core Lecture Series; Lecturer (2005–2010)
  • Lucile Packard Children's Hospital: Pediatric Hematology/Oncology Bereavement Committee; Committee Member (2003–2016)
  • Stanford University: Pediatric Oncology Bereavement Program; Faculty Supervisor (2003–2016)
  • Stanford University: Pediatric Residency Program - Hematology/Oncology Ambulatory Selective Rotation; Director (2003–2015)
  • Stanford University: Pediatric Residency Program - Hematology/Oncology Inpatient Rotation; Director (2003–2012)
  • New Approaches to Neuroblastoma Therapy Consortium: Study Committee; NANT 2001-2003: A Phase I Study of CEP-701 in Patients with Refractory Neuroblastoma; Committee Member (2003–2010)
  • New Approaches to Neuroblastoma Therapy Consortium: Data Safety and Monitoring Committee; Committee Member (2003–present)
  • Lucile Packard Children‘s Hospital: Division of Hematology/Oncology Peer Review Committee; Chair (2002–2015)
  • Children's Oncology Group: Intermediate Risk Neuroblastoma Study (ANBL0531); Chair (2002–2013)
  • Stanford University School of Medicine: Medical Student Sub-Internship in Pediatric Hematology/Oncology; Director (2002–2012)
  • Lucile Packard Children's Hospital: Care Improvement Committee; Committee Member (2001–2016)
  • American Academy of Pediatrics: PREP; Editorial Board Member (2001–2003)
  • New Approaches to Neuroblastoma Therapy Consortium: Neuroblastoma Disease Committee; Committee Member (2001–present)
  • Stanford University: Pediatric Oncology Tumor Board; Faculty Supervisor (2000–2016)
  • Lucile Packard Children's Hospital: Quality Improvement Committee; Committee Member (2000–2015)
  • Lucile Packard Children's Hospital: Division of Pediatric Hematology/Oncology; Quality Assurance Liaison (2000–2014)
  • Lucile Packard Children's Hospital: Critical Care Committee; Committee Member (2000–2009)
  • Stanford University School of Medicine: Medical Student Clerkship in Pediatric Hematology/Oncology; Director (2000–2005)
  • Lucile Packard Children's Hospital: Pediatric Oncology Medication Error Committee; Committee Member (2000–2002)
  • Pediatric Bone and Marrow Transplant Consortium: Immunologic and Metabolic Disorders Strategy Group; Member (2000–2002)
  • Lucile Packard Children's Hospital: Sedation Committee; Committee Member (2000–2001)
  • Journal of Clinical Oncology; Ad Hoc Reviewer (2000–present)
  • Journal of Pediatric Hematology/Oncology; Ad Hoc Reviewer (2000–present)
  • Dana-Farber Cancer Institute: Marathon Challenge Governing Board; Board Member (1998–present)
  • Dana-Farber Cancer Institute: Committee on Sexual Harassment; In-House Sexual Harassment Trainer (1997–1999)
  • Dana-Farber Cancer Institute: Human Protection Committee; Committee Member (1996–1999)
  • Dana-Farber Cancer Institute: Pediatric Oncology Operations Committee; Committee Member (1996–1999)
  • Boston Children‘s Hospital: Oncology/Bone Marrow Transplant Resident Education Committee; Committee Member (1994–1999)
  • Dana-Farber Cancer Institute: Pediatric Oncology Clinic; Clinic Leader (1994–1998)
  • Dana-Farber Cancer Institute: Marathon Challenge Patient Partner Program Committee; Committee Member (1994–present)
  • Harvard Medical School: Patient-Doctor II Course in Physical Diagnosis; Tutor (1993–1996)
  • Dana-Farber Cancer Institute: Pediatric Oncology Protocol Conference; Coordinator (1993–1994)
  • Dana-Farber Cancer Institute: Marathon Challenge for Claudia Adams Barr Program in Innovative Basic Cancer Research; Participant (1993–present)
  • Albany Medical College: Admissions Committee; Committee Member (1985–1987)
  • Children's Oncology Group: Roswell Park Comprehensive Cancer Center; Site Principal Investigator

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Contact Information

Roswell Park Cancer Institute
Department of Pediatrics
Elm and Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-2333
Fax: (716) 845-8003
ctwist@buffalo.edu

Looking for a doctor? This faculty member is affiliated with UBMD, the group comprised of practicing physicians who are also professors in the UB Jacobs School of Medicine and Biomedical Sciences.

View this faculty on UBMD