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Joseph                         Izzo

Joseph L. Izzo MD

Department of Medicine

Professor and Chief, Clinical Pharmacology

Specialty/Research Focus

Cardiac pharmacology; Cardiovascular Disease; Internal Medicine; Nephrology; Pathophysiology; Vascular and Interventional Radiology

 
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Professional Summary:

(1) Role of the sympathoadrenal system in hypertension, postural adaptation, and long-term cardiovascular adaptation
(2) Control of regional and systemic blood flow during acute stress responses
(3) Mechanisms of stress responses and vasoreactivity, both in vivo and in vitro, including metabolic interactions
(4) Cardiovascular drug effects
(5) Outcomes of drug therapies

Education and Training:
  • Staff Associate, Experimental Therapeutics Section, Hypertension-Endocrine Branch, National Heart, Lung and Blood Institute (1979)
  • Attending Physician, Clinical Center, National Institutes of Health (1979)
  • Internship, Straight Medicine, Barnes Hospital, Washington University (1974)
  • MD, Internal Medicine, Johns Hopkins University (1972)
  • AB, Biology/Biochemistry, Princeton University (1968)
Employment:
  • Chief of Medicine, Erie County Medical Center (2004-present)
  • Professor of Pharmacology and Toxicology, University at Buffalo (1991-present)
  • Professor of Medicine, University at Buffalo (1990-present)
  • Associate Program Director, Internal Medicine Training Program, University York at Buffalo (2004–2008)
  • Vice Chair for Research, Department of Medicine, State University of New York at Buffalo (1999–2006)
  • Director, FDA Clinical Pharmacology Fellowship Training Program, University at Buffalo (1992–2002)
  • Program Director, Internal Medicine Training Program B, State University of New York at Buffalo (1988–2001)
  • Chairman, Department of Medicine, Millard Fillmore Health System (1988–1998)
  • Adjunct Associate Professor of Medicine, University of Rochester School of Medicine (1988–1991)
  • Associate Professor, University at Buffalo (1988–1990)
  • Associate Professor; Attending Physician, Department of Medicine, University of Rochester School of Medicine (1984–1988)
  • Director, Hypertension Service, University of Rochester School of Medicine (1980–1988)
  • Assistant Professor of Medicine; Associate Physician, (Nephrology), University of Rochester School of Medicine, School of Medicine (1979–1984)
  • Guest Worker, Experimental Therapeutics Section, Hypertension Endocrine Branch, National Heart, Lung and Blood Institute, National Institutes of Health (1979–1980)
  • Staff Associate, Experimental Therapeutics Section, Hypertension-Endocrine Branch, National Heart, Lung and Blood Institute, NIH Bethesda, Maryland (1975–1979)
  • Attending Physician, National Institutes of Health Bethesda Maryland (1975–1979)
  • Physician, part time, Urgent Care Clinic, Columbia Medical Group (1975–1978)
  • Consultant in Emergency Medicine and Acting Assistant Director of Emergency Services, Howard County General Hospital (1974–1975)
  • Lecturer in Medicine, School of Health Services, Johns Hopkins University (1974–1975)
  • Intern and Assistant Resident, Straight Medicine, Washington University, Barnes Hospital (1972–1974)
See All (20 Total) >
Awards and Honors:
  • American Society of Hypertension, Marvin Moser Clinical Hypertension Award (2012)
  • Who's Who (2011)
  • American Society of Hyptertension, Fellow (2010)
  • American Society of Hyptertension, Hypertension Specialist (1999)
  • Best Doctors in America (1996)
  • American Heart Association, Fellow (1995)
  • American College of Physicians, Fellow (1990)
  • Who's Who in Science (1984)
  • Who's Who in the East (1984)
  • Fellow, High Blood Pressure Research Council, AHA (1984)
  • Sinsheimer Scholar Award (1982)
  • Clinical Associate Physician Award, University of Rochester (1979)
  • Buswell Fellow, University of Rochester (1979)
  • National Merit Scholarship Finalist (1964)
  • Hearst Foundation Senate Youth Fellow (1964)

Research Expertise:
  • New Research Expertise
Grants and Sponsored Research:
  • June 2001–December 2002
    Hemodynamic Profiling of Carvedilol
    Glaxo Smith-Kline
    Role: Principal Investigator
    $195,000
  • October 1992–September 2002
    Pilot Clinical Pharmacology Training Program
    US Food and Drug Administration and USPHS
    Role: Principal Investigator
    $2,055,000
  • January 1989–December 1994
    Coronary Arrhythmia Suppression Trial
    NHLBI, NIH
    Role: Principal Investigator
    $125,000
  • January 1986–January 1988
    Seasonal Blood Pressure Variation
    American Heart Association, NYS Affiliate
    Role: Principal Investigator
    $49,000

Evaluative Studies and Case Reports:
Journal Articles:
See All (145 Total) >
Books and Book Chapters:
  • Izzo JL; Sica,D.A.; Black, H.R.. Hypertension Primer, Fourth Edition. 2008.
  • Izzo JL; Black, H.R.. Hypertension Primer, Third Edition. 2003.
  • Izzo JL, Black, H.R.. Hypertension Primer, Second Edition. 1999.
  • Joseph Izzo, Black, H.R., Taubert, K.. Hypertension Primer. 1993.
  • Joseph Izzo. Angiotensin converting enzyme inhibition. 1983.

Professional Memberships:
  • American Society of Hypertension; Ad hoc advisory group for organizational strategic planning (2013)
  • American Society of Hypertension; Fellow of the American Society of Hypertension (2010)
  • American Society of Hypertension; Physician Leader and founder, ASH Community Outreach Programs, New York initiatives (2009)
  • Amercian Society of Hypertension; Physician Leader and founder, ASH Community Outreach Programs, San Francisco initiatives (2008)
  • American Society of Hypertension; Hypertension Education Development Group (2007–2010)
  • American Society of Hypertension; Scientific Publications and Clinical Advisory Committee (2007–2009)
  • American Society of Hypertension; Physician Leader and founder, ASH Community Outreach Programs, New Orleans initiatives (2007)
  • American Society of Hypertension; Treasurer (2006–2009)
  • American Society of Hypertension; Executive Committee (2006–2009)
  • American Society of Hypertension; Finance Committee (Chair) (2006–2009)
  • American Heart Association - National Organization; Ischemic Heart Disease Guideline Development Group (2006–2007)
  • American Society of Hypertension; Scientific Program Committee (2005–2008)
  • American Society of Hypertension; Executive Council (2005–2006)
  • American Society of Hypertension; Conflict of Interest Study Committee (2004–2006)
  • American Society of Hypertension; Board of Directors (2003–2009)
  • Amercian Heart Association - Council for High Blood Pressure Research; Finance Committee (2003–2005)
  • American Heart Association - National Organization; Medical Editorial Board (2002)
  • Amercian Heart Association - Council for High Blood Pressure Research; Scientific Sessions Program Committee (2001–2004)
  • American Society of Hypertension; Continuing Medical Education Committee (2001–2004)
  • American Heart Association - National Organization; Fellow of the American Heart Association (2001)
  • United States Pharmacopeia; USP Counsel of Experts, Cardiovascular and Renal Drugs Expert Committee (2000–2005)
  • American Society of Hypertension; National Specialist Examination Subcommittee (1999–2005)
  • American Society of Hypertension; Specialist Committee (1999–2001)
  • Amercian Society of Hypertension; Nominating Committee (1999–2000)
  • American Society of Hypertension; Professional Education Committee member (1998–2004)
  • American Heart Association - National Organization; Continuing Education Committee (AHA National Committee) (1997–2000)
  • American College of Physicians; Councilor for Upstate Region (New York State Chapter) (1996–2000)
  • Amercian Heart Association - Council for High Blood Pressure Research; Publications Committee (1996–1999)
  • United States Pharmacopeia; USP Revisions Panel for Cardiorenal Drugs, 1995-2000 (1995–2000)
  • American Heart Association - National Organization; Expert Panel on Cardiovascular Drugs (1994–2004)
  • Council on Geriatric Cardiology; Fellow (1994–2000)
  • Amercian Society for Clinical Pharmacology and Therapeutics; Chairman, Hypertension Section (1994–1997)
  • Buffalo Academy of Medicine; President (1994–1996)
  • Amercian Heart Association - Council for High Blood Pressure Research; Professional Education Committee Chairman (1993–1996)
  • Amercian Heart Association - Council for High Blood Pressure Research; Executive Committee member (1993–1996)
  • Amercian Heart Association - Council for High Blood Pressure Research; Long Range Planning Committee member (1993–1996)
  • Amercian Autonomic Society; Member (1992–2004)
  • Amercian Heart Association - Council for High Blood Pressure Research; Scientific Program Abstract Grader (1992)
  • Society for Vascular biology and Medicine; Member (1990–2002)
  • American Society for Clinical Pharmacology and Therapeutics; Abstract Reviewer (1990–1993)
  • American Society for Clinical Pharmacology and Therapeutics; Co-Chairman, Hypertension Section (1990–1993)
  • Amercian Heart Association - Council for High Blood Pressure Research; Chairman, Hypertension Curriculum Committee (1990–1991)
  • Association of Program Directors of Internal Medicine; Member (1988–2001)
  • Buffalo Academy of Medicine; Member (1988–1998)
  • American Society of Nephrology; Chairman, Hypertension Section (1987)
  • Amercian Heart Association - Council for High Blood Pressure Research; Professional Education Committee Member (1986–1993)
  • American Society of Hypertension; Scientific Program Abstract Grader (1986)
  • National Kidney Foundation of Upstate New York; Medical Advisory Board (1985–1987)
  • National Kidney Foundation of Upstate New York; Chairman, Scientific Grant Review Committee (1985–1987)
  • American Society of Nephrology; Scientific Program Abstract Grader (1984–1986)
  • Interantional Society for Hypertension; Member (1984)
  • Amercian Heart Association - Council for High Blood Pressure Research; Fellow (1983)
  • American Society of Hypertension; Founding Member (1983)
  • International Scoiety of Nephrology; member (1982–1993)
  • New York Academy of Sciences; Member (1982–1984)
  • Amercian Heart Association - NYS Affiliate; Hypertension Committee (1982–1984)
  • Amercian Heart Association - Council on the Kidney in Cardiovascular Disease; Member (1982)
  • Amercian Association for the Advancement of Science; Member (1981–1984)
  • American Federation for Biomedical Research; Member (1980–2000)
  • Inter-American Society for Hypertension; Member (1980)
  • American Society of Nephrology; Member (1979–2002)
Presentations:
  • "Estrogen may influence blood pressure regulation" Thirteenth Scientific Meeting of the American Society of Hypertension, American Society of Hypertension (1998)
  • "Normalization of hypertensive responses during ambulatory surgical stress by perioperative music" Thirteenth Scientific Meeting of the American Society of Hypertension (1998)
Service Activities:
  • Faculty Senate; Member (2001)
  • Biochemistry, School of Medicine & Biomedical Sciences Sample Committee; Member (1999)
  • Biochemistry, School of Medicine & Biomedical Sciences Sample Committee; Member (1999)
  • Biochemistry, School of Medicine & Biomedical Sciences Sample Committee; Chair (1999)
  • School of Medicine & Biomedical Sciences Faculty Council; Alternate Member (1998–2002)
  • School of Medicine & Biomedical Sciences Faculty Council; Member (1989)
  • Combined ARB_neprolysin (LCZ) in Systolic Hypertension; Combined ARB-neprolysin (LCZ) in Systolic Hypertension; International Principal Investigator and Chair,Executive Committee, Novartis Pharmaceuticals (2011–2013)
  • Visiting Professorship; New York University (Cardiology); Visiting Professor (2009)
  • Visiting Professorship; SUNY-Brooklyn (Medicine and Endocrinology); Visiting Professor (2008)
  • Visiting Professorship; Temple University (Cardiology); Visiting Professor (2008)
  • TRINITY (Triple Combination therapy in Hypertension); TRINITY(Triple Combination therapy in Hypertension)Study Executive Committee and National Principal Investigator , Daiichi-Sankyo (2008–2010)
  • Visiting Professorship; University of Mississippi (Medicine and Pharmacology); Visiting Professor (2007)
  • Visiting Professorship; Tufts University (Cardiology); Visiting Professor (2007)
  • VALVET; VALVET (Valsartan-hydrochlorothiazide combination in Very Elderly Subjects with Essential Hypertension)Executive Committee and National Principal Investigator (2007–2013)
  • Visiting Professorship; Emory University (Cardiology and Medicine); Visiting Professor (2007)
  • Visiting Professorship; Tulane University (Physiology); Visiting Professor (2006)
  • EXFAST; EXFAST (Exforage and Systolic Hypertension) Study Executive Committee and National Principal Investigator, Novartis (2006–2008)
  • EXCEED; EXCEED (Exforage and Diastolic Dysfunction)Study Executive Committee, Novartis (2006)
  • Visiting Professorship; Medical College of Ohio (Medicine); Visiting Professor (2005)
  • Visiting Professorship; Yale University (Cardiothoracic Surgery); Visiting Professor (2004)
  • Visiting Professorship; University of Pittsburgh (Cardiology); Visiting Professor (2004)
  • Visiting Professorship; University of Rochester (Cardiology); Visiting Professor (2003)
  • Visiting Professorship; university of Rochester (Cardiology); Visiting Professor (2003)
  • Visiting Professorship; University Medical Center of South Neveda (Medicine); Visiting Professor (2003)
  • Visiting Professorship; University of Rochester (Cardiology); Visiting Professor (2003)
  • Visiting Professorship; George Washington University (Pharmacology); Visiting Professor (2003)
  • Visiting Professorship; SUNY at Syracuse (Nephrology); Visiting Professor (2003)
  • Visiting Professorship; University of Western Ontario (Clinical Pharmacology); Visiting Professor (2003)
  • ValMARC; ValMARC (Valsartan and CRP)Study Executive Committee; Committee Member (2003–2005)
  • ROADMAP; ROADMAP (Randomized Olmesartan And Diabetic Microalbuminuria Prevention) Study Executive Committee, Daiichi-Sanko (2003)
  • Visiting Professor; SUNY-Brooklyn (Endocrinology), 12/01; Visiting Professor (2001)
  • Visiting Professorship; University of Western Ontario (Clinical Pharmacology); Visiting Professor (2001)
  • Visiting Professor; Mount Sinai School of Medicine (Hypertension), 2/01; Visiting Professor (2001)
  • AMAZE; AMAZE ("Antihypertensive Efficacy of Adding Candesartan Cilexetil to Lisinopril in Comparision to Up-Titration of Lisinopril:A Multi-Center Trial Using Atacand-Zestril to Evaluate the Efects on Lowering Blood Pressure," National Lead Investigator; National Liaison (2001–2002)
  • Visting Professorship; University of California, San Francisco (Cardiology) 12/00; Visiting Professor (2000)
  • Visiting Professor; Long Island Jewish Medical Center (General Medicine), 11/00; Visiting Professor (2000)
  • Visiting Professorship; University of Connecticut Health Center (Hypertension); Visiting Professor (2000)
  • Visiting Professorship; University of Western Ontario (Clinical Pharmacology); Visiting Professor (2000)
  • Visiting Professorship; Medical College of Wisconsin (Hypertension); Visiting Professor (2000)
  • Visiting Professorship; University of Connecticut Health Center (Hypertension); Visiting Professor (2000)
  • Visiting Professorship; SUNY at Syracuse (Nephrology); Visiting Professor (2000)
  • Visiting Professorship; University of Hawaii (Medicine); Visiting Professor (2000)
  • Visiting Professorship; University of Pittsburgh (Cardiology); Visiting Professor (2000)
  • Visiting Professorship; Rush Medical College (Preventive Medicine); Visiting Professor (2000)
  • New Service Activity; Boy Scouts of America Merit Badge Counselor; Volunteer (2000)
  • Visiting Professorship; University of Calgary (Cardiology and Physiology); Visiting Professor (1999)
  • Visiting Professorship; University of Edmonton (Cardiology); Visiting Professor (1999)
  • Visiting Professorship; Rush Medical College (Preventive Medicine); Visiting Professor (1999)
  • TROPHY (Trial of Prevention of Hypertension); (Trial of Prevention of Hypertension) Study, Data Safefty Monitoring Board, Astra Zeneca; Board Member (1999–2005)
  • Editorial Board; Reviews in Cardiovascular Medicine; Editorial Board Member (1999–2001)
  • Editorial Board; Journal of Clinical Hypertension; Editorial Board Member (1999)
  • Visiting Professorship; Wayne State University (Endocrinology); Visiting Professor (1998)
  • Visiting Professorship; Albany Medical College (Medicine); Visiting Professor (1997)
  • Visiting Professorship; Albany Medical College (Cardiology); Visiting Professor (1997)
  • Visiting Professorship; Northeastern Ohio Consortium (Medicine); Visiting Professor (1997)
  • Visiting Professorship; Susquehanna Health System (Medicine); Visiting Professor (1996)
  • Visiting Professorship; University of Illinois-Peoria (Clinical Pharmacology); Visiting Professor (1996)
  • Visiting Professorship; Albany Medical College (Cardiology and Medicine); Visiting Professor (1995)
  • Visiting Professorship; Meharry Medical College (Clinical Pharmacology); Visiting Professor (1994)
  • New Service Activity; Fellow, Council on Geriatric Cardiology; Member (1994)
  • Visiting Professorship; Albany Medical College(Cardiology); Visiting Professor (1993)
  • Visiting Professorship; Thomas Jefferson University (Clinical Pharmacology); Visiting Professor (1993)
  • Visiting Professorship; Tulane University (Cardiology); Visiting Professor (1993)
  • Visiting Professorship; University of Western Ontario (Clinical Pharmacology); Visiting Professor (1993)
  • Visiting Professorship; Northeastern Ohio Consortium (Medicine); Visiting Professor (1992)
  • Visiting Professorship; Pennsylvania State University (Nephrology); Visiting Professor (1992)
  • Visiting Professorship; Pennsylvania State University (Nephrology); Visiting Professor (1992)
  • Visiting Professorship; Yale University (Cardiology); Visiting Professor (1992)
  • Visiting Professorship; University of Michigan (Hypertension); Visiting Professor (1991)
  • Visiting Professorship; Medical College of Ohio (Medicine); Visiting Professor (1991)
  • Visiting Professorship; Albany Medical College (Cardiology and Medicine); Visiting Professor (1990)
  • Clinical Service; Hypertension Consultations (weekly, 1/2 day); Other (1990)
  • Visiting Professorship; West Virginia University (Nephrology); Visiting Professor (1988)
  • Clinical Service; Attending Physician, General Medicine, 2 months per year; Volunteer (1988)
  • Visiting Professorship; Henry Ford Hospital (Nephrology); Visiting Professor (1987)
  • Visiting Professorship; SUNY at Syracuse (Nephrology); Visiting Professor (1987)
  • Visiting Professorship; University of California, San Diego (Nephrology); Visiting Professor (1986)
  • Visiting Professorship; University of Kansas (Nephrology); Visiting Professor (1986)
  • Visiting Professorship; Yale University (Hypertension); Visiting Professor (1986)
  • Visiting Professorship; Temple University (Nephrology); Visiting Professor (1985)
  • Visiting Professorship; John Hopkins University School of Medicine (Nephrology); Visiting Professor (1984)
  • Visiting Professorship; Rutgers University (Physiology); Visiting Professor (1983)
  • Visiting Professorship; Johns Hopkins University School of Medicine (Nephrology); Visiting Professor (1983)
  • Visiting Professorship; Cleveland Clinic Foundation (Hypertension); Visiting Professor (1983)
  • Visiting Professorship; Albany Medical College (Nephrology); Visiting Professor (1982)
  • Visiting Professorship; NHLBI, NIH (Experimental Therapeutics) 5/82; Visiting Professor (1982)

Clinical Specialties:
Clinical Offices:
Insurance Accepted:

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Contact Information

Erie County Medical Center
462 Grider Street
Buffalo, NY 14215
Phone: (716) 898-5234
Fax: (716) 898-4493
Email: jizzo@buffalo.edu

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