Joseph B. Kuechle MD, PhD
Joseph B. Kuechle
MD, PhD
Clinical Assistant Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Lower Extremity Joint Replacement & Reconstruction; Orthopaedic Oncology
Education and Training:
- Fellowship, Musculoskeletal Oncology, Harvard University (2016)
- Residency, Orthopaedic Surgery, University at Buffalo (2015)
- PhD, Bioengineering, Cell and Tissue Engineering, University of Illinois at Chicago (2010)
- MD, Doctor of Medicine, University of Illinois at Chicago (2010)
- BS, Chemical Engineering, University at Buffalo, Magna Cum Laude (2002)
Employment:
- EMT-B, Rural/Metro Ambulance (2000–2002)
Journal Articles:
- Biermann JS, Chow W, Reed DR, Lucas D, Adkins DR, Agulnik M, Benjamin RS, Brigman B, Budd GT, Curry WT, Didwania A, Fabbri N, Hornicek FJ, Kuechle JB, Lindskog D, Mayerson J, McGarry SV, Million L, Morris CD, Movva S, O'Donnell RJ, Randall RL, Rose P, Santana VM, Satcher RL, Schwartz H, Siegel HJ, Thornton K, Villalobos V, Bergman MA, Scavone JL. NCCN Guidelines Insights: Bone Cancer, Version 2.2017. J Natl Compr Canc Netw. 2017; 15(2).
- Kuechle JB, McGrath BE, Khoury T, Mindell ER. A case of long term survival with skeletal only metastatic breast cancer. Int J Surg Case Rep. 2014; 6C.
- McGrath BE, Kuechle JB. Hip arthroscopic portal bridge retraction technique for improved peripheral compartment visualization. Arthrosc Tech. 2014; 3(4).
- Qi M, Strand BL, Mørch Y, Lacík I, Wang Y, Salehi P, Barbaro B, Gangemi A, Kuechle J, Romagnoli T, Hansen MA, Rodriguez LA, Benedetti E, Hunkeler D, Skjåk-Braek G, Oberholzer J, Kuechle JB. Encapsulation of human islets in novel inhomogeneous alginate-ca2+/ba2+ microbeads: in vitro and in vivo function. Artif Cells Blood Substit Immobil Biotechnol. 2008; 36(5).
- Barbaro B, Kuechle J, Salehi P, Rodriguez L, Qi M, Gangemi A, Benedetti E, Oberholzer J, Kuechle JB. Increased albumin concentration reduces apoptosis and improves functionality of human islets. Artif Cells Blood Substit Immobil Biotechnol. 2008; 36(1).
- Barbaro B, Salehi P, Wang Y, Qi M, Gangemi A, Kuechle J, Hansen MA, Romagnoli T, Avila J, Benedetti E, Mage R, Oberholzer J, Kuechle JB. Improved human pancreatic islet purification with the refined UIC-UB density gradient. Transplantation. 2007; 84(9).
- Avila JG, Wang Y, Barbaro B, Gangemi A, Qi M, Kuechle J, Doubleday N, Doubleday M, Churchill T, Salehi P, Shapiro J, Philipson LH, Benedetti E, Lakey JR, Oberholzer J, Kuechle JB. Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier. Am J Transplant. 2006; 6(12).
- Avila J, Barbaro B, Gangemi A, Romagnoli T, Kuechle J, Hansen M, Shapiro J, Testa G, Sankary H, Benedetti E, Lakey J, Oberholzer J, Kuechle JB. Intra-ductal glutamine administration reduces oxidative injury during human pancreatic islet isolation. Am J Transplant. 2005; 5(12).
- Kalinichenko VV, Major ML, Wang X, Petrovic V, Kuechle J, Yoder HM, Dennewitz MB, Shin B, Datta A, Raychaudhuri P, Costa RH, Kuechle JB. Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev. 2004; 18(7).
Evaluative Studies and Case Reports:
- Kuechle JB, Pasha S, Sadat K, Tran J, Hatipoglu B, Bui JT, Chejfec G, Oberholzer J. Pulmonary sequestration with CCAM type II appearing as adrenal tumor protruding through a Bochdalek hernia. Int J Surg Pathol. 2011; 19(2).
- Giulianotti PC, Kuechle J, Salehi P, Gorodner V, Galvani C, Benedetti E, Oberholzer J, Kuechle JB. Robotic-assisted laparoscopic distal pancreatectomy of a redo case combined with autologous islet transplantation for chronic pancreatitis. Pancreas. 2009; 38(1).
Professional Memberships:
- American Academy of Orthopaedic Surgeons
- American Medical Association
- American Physician Scientist Association
- Biomedical Engineering Society
Presentations:
- "Impact of the addition of a fully threaded posterior screw for fixation of minimally displaced femoral neck fractures" Annual Eugene R. Mindell, M.D. Orthopaedic Residency Scientific Program (2014)
- "30 Year Single Institution Review of Osteosarcoma Survival and r GCSF Impact" Musculoskeletal Tumor Society Annual Meeting. (2013)
- "Metastatic Disease in Orthopedics" Orthopedics Grand Rounds, University at Buffalo (2013)
- "30 Year Single Institution Review of Osteosarcoma Survival and r GCSF Impact" Annual Eugene R. Mindell, M.D. Orthopaedic Residency Scientific Program (2013)
- "Reduced Titanium Biocompatibility Under Varied Cathodic Currents and Exposure Durations" Annual Eugene R. Mindell, M.D., Orthopaedic Residency Scientific Program (2012)
- "Breast Cancer Metastasis: Combating lethal seeds" Oncology Grand Rounds, University of Illinois at Chicago (2010)
- "TAT SV40T Fusion Protein Mediated Islet Cell Proliferation Induction" American Transplant Congress Conference (2008)
- "Engineering better drug delivery for colon cancer" Oncology Grand Rounds, University of Illinois at Chicago (2008)
- "Islet cell proliferation induction using cell cycle modulating TAT fusion proteins" International Pancreas & Islet Transplant Association (2007)
- "Impact of Catheter Characteristics on Pancreatic Islet Graft Integrity" Society of Interventional Radiology Annual Meeting (2007)
- "Regional Variation in the Micro-elastic Properties of the Rabbit Annulus Fibrosis upon Nano-indentation with Atomic Force Microscopy" Orthopedic Research Society Meeting (2003)
- "A Novel Cell Adhesion Studying Technique" National Science Foundation Research Experience for Undergraduates Meeting (2001)