Students Residents Faculty and StaffAlumni

Michael D. Sitrin MD

Department of Medicine

Professor

Specialty/Research Focus

Gastroenterology

Overview Research Publications

Education and Training:

MD, Medicine, Harvard Medical School (1974)
BS, Zoology, University of Michigan, high honors (1970)

Employment:

Division of Gastroenterology and Nutrition, VA Western New York Healthcare System (2002-present)
Professor of Medicine
Medical Director, University of Chicago (1985–2002)
Adult Nutrition Support Service, University of Chicago (1980–2002)
Director, University of Chicago (1987–1985)

Awards and Honors:

Phi Beta Kappa
Okkleberg Award in Zoology
Phi Sigma Society for Biological Society
Phi Sigma Society Award for excellence in Biology
Alpha Omega Alpha Society, Harvard Medical School
Upjohn Outstanding Resident in Illinois Award
Beatrice Faculty Scholar Award
Burroughs Wellcome Fund Welcome Research Travel Grant
2001-2004 Selected for inclusion in Best Doctors in the US
Chicago Chapter of The American Society for Parenteral and Enteral Nutritio
Who’s Who (Medicine)

Grants and Sponsored Research:

January 2007–December 2008
Procurement of fasting blood samples for use in the development of a gastrointestinal disease test panel.
Prometheus Laboratories
Role: Principal Investigator
$12,750
January 2007–December 2008
A Multicenter, Randomized, Placebo-Controlled, Double-Blinded Study of the Efficacy and Safety of Lubiprostone in Patients with Opioid-Induced Bowel Dysfunction,
Sucampo/Takeda Pharmaceuticals
Role: Principal Investigator
$30,000
January 2006–December 2007
A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of DNK333 25 mg b.i.d. given orally for 4 weeks in female patients with Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
Novartis Pharmaceutical
Role: Principal Investigator
$45,000
April 1997–March 2004
Rat intestinal membranes: vitamin D mediated effects .
NIH
Role: Co-Investigator
$196,835
“Development of a mouse model of NASH”
VA VISN 2 Research Incentive Funds 2004
Role: Principal Investigator
$15,000

Evaluative Studies and Case Reports:

Tian C, Sitrin MD, Samuel SJ. Chest wall hematoma after percutaneous liver biopsy. Clin Gastroenterol Hepatol. 2010; 8(7).
Fayyaz M, Mehboob S, Andersen V., Sitrin MD. Extended Octreotide Suppression test to determine hormone responsiveness of multiple Type I Gastric Carcinoid Tumors. (Case Report). Digestive Diseases and Sciences 2007. 2007; 52(6).
Fayyaz M, Mehboob S, Andersen V, Sitrin MD. Extended octreotide suppression test to determine hormone responsiveness of multiple type I gastric carcinoid tumors. Dig Dis Sci. 2007; 52(6).
Cheng H, Sitrin MD, Satchidanand SK, Novak JM. Colonic squamous cell carcinoma in ulcerative colitis: Report of a case and review of the literature. Can J Gastroenterol. 2007; 21(1).
Cheng H, Sitrin MD, Rani A. Angiomyolipoma in the colon. Gastrointest Endosc. 2006; 64(3).
Rafiq S, Hameer H, Sitrin MD. Ganglioneuromatous polyposis associated with juvenile polyps and a tubular adenoma. Dig Dis Sci. 2005; 50(3).
Cheng H, Cook M, Sitrin MD. Image of the month. Gallstone ileus. Gastroenterology. 2004; 127(3).
Barak N, Hart J, Sitrin MD. Enalapril-induced eosinophilic gastroenteritis.. J Clin Gastroenterol. 2001; 33(2).
Knowles JB, Cusson G, Smith M, Sitrin MD. Pulmonary deposition of calcium phosphate crystals as a complication of home total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1989; 13(2).
Derus CL, Levinson DJ, Bowman B, Bengoa JM, Sitrin MD. Altered fractional excretion of uric acid during total parenteral nutrition. J Rheumatol. 1987; 14(5).
Sitrin MD, Lieberman F, Jensen WE, Noronha A, Milburn C, Addington W. Vitamin E deficiency and neurologic disease in adults with cystic fibrosis. Ann Intern Med. 1987; 107(1).
Kushner RF, Sitrin MD. Metabolic acidosis. Development in two patients receiving a potassium-sparing diuretic and total parenteral nutrition. Arch Intern Med. 1986; 146(2).
Weinberg RB, Sitrin MD, Adkins GM, Lin CC. Treatment of hyperlipidemic pancreatitis in pregnancy with total parenteral nutrition.. Gastroenterology. 1982; 83(6).
Sitrin MD, Rosenberg IH, Chawla K, Meredith S, Sellin J, Rabb JM, Coe F, Kirsner JB, Kraft SC. Nutritional and metabolic complications in a patient with Crohn's disease and ileal resection.. Gastroenterology. 1980; 78(5 Pt).

See All (14 Total) >

Journal Articles:

Gupta A, Pendyala P, Arora P, Sitrin MD. Development of the nephrotic syndrome during treatment of Crohn's disease with adalimumab. J Clin Gastroenterol. 2011; 45(3).
Chadha KS, Thatikonda C, Schiff M, Nava H, Sitrin MD. Outcomes of percutaneous endoscopic gastrostomy tube placement using a T-fastener gastropexy device in head and neck and esophageal cancer patients. Nutr Clin Pract. 2010; 25(6).
Chadha KS, Schiff M, Sitrin MD, Wilding GE, Nava H. Clinical outcomes of using a conservative approach of late esophageal stent placement in palliation of malignant dysphagia. J Gastrointest Cancer. 2010; 41(3).
Gupta A, Sitrin MD. Concomitant therapy of Crohn's disease and hepatitis C with budesonide and antivirals. Gastroenterol Hepatol (N Y). 2010; 6(8).
Lackner JM, Brasel AM, Quigley BM, Keefer L, Krasner SS, Powell C, Katz LA, Sitrin MD. The ties that bind: perceived social support, stress, and IBS in severely affected patients. Neurogastroenterol Motil. 2010; 22(8).
Sarosiek I, Selover KH, Katz LA, Semler JR, Wilding GE, Lackner JM, Sitrin MD, Kuo B, Chey WD, Hasler WL, Koch KL, Parkman HP, Sarosiek J, McCallum RW. The assessment of regional gut transit times in healthy controls and patients with gastroparesis using wireless motility technology. Aliment Pharmacol Ther. 2010; 31(2).
Hasler WL, Saad RJ, Rao SS, Wilding GE, Parkman HP, Koch KL, McCallum RW, Kuo B, Sarosiek I, Sitrin MD, Semler JR, Chey WD. Heightened colon motor activity measured by a wireless capsule in patients with constipation: relation to colon transit and IBS. Am J Physiol Gastrointest Liver Physiol. 2009; 297(6).
Rao SS, Kuo B, McCallum RW, Chey WD, Dibaise JK, Hasler WL, Koch KL, Lackner JM, Miller C, Saad R, Semler JR, Sitrin MD, Wilding GE, Parkman HP. Investigation of Colonic and Whole Gut Transit with Wireless Motility Capsule and Radioopaque Markers in Constipation. Clin Gastroenterol Hepatol. 2009.
Samuel S, Sitrin MD. Vitamin D's role in cell proliferation and differentiation. Nutr Rev. 2008; 66(10 Su).
Bolt MJ, Cao LP, Kong J, Sitrin MD, Li YC. Vitamin D receptor is required for dietary calcium-induced repression of calbindin-D9k expression in mice. J Nutr Biochem. 2005; 16(5).
Bolt MJ, Liu W, Qiao G, Kong J, Zheng W, Krausz T, Cs-Szabo G, Sitrin MD, Li YC. Critical role of vitamin D in sulfate homeostasis: regulation of the sodium-sulfate cotransporter by 1,25-dihydroxyvitamin D3. Am J Physiol Endocrinol Metab. 2004; 287(4).
Bolt MJ, Liu W, Qiao G, Kong J, Zheng W, Krausz T, Cs-Szabo G, Sitrin MD, Li YC. Critical Role of Vitamin D in Sulfate Homeostasis: Regulation of the Sodium-Sulfate Co-transporter by 1,25-Dihydroxyvitamin D3.. Am J Physiol Endocrinol Metab. 2004.
Khare S, Cerda S, Wali RK, von Lintig FC, Tretiakova M, Joseph L, Stoiber D, Cohen G, Nimmagadda K, Hart J, Sitrin MD, Boss GR, Bissonnette M. Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer.. Cancer Res. 2003; 63(13).
Chung PY, Sitrin MD, Te HS. Serum phosphorus levels predict clinical outcome in fulminant hepatic failure.. Liver Transpl. 2003; 9(3).
Wali RK, Kong J, Sitrin MD, Bissonnette M, Li YC. Vitamin D receptor is not required for the rapid actions of 1,25-dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts.. J Cell Biochem. 2003; 88(4).
Barak N, Wall-Alonso E, Cheng A, Sitrin MD. Use of bioelectrical impedance analysis to predict energy expenditure of hospitalized patients receiving nutrition support. JPEN J Parenter Enteral Nutr. 2003; 27(1).
Wali RK, Stoiber D, Nguyen L, Hart J, Sitrin MD, Brasitus T, Bissonnette M. Ursodeoxycholic acid inhibits the initiation and postinitiation phases of azoxymethane-induced colonic tumor development.. Cancer Epidemiol Biomarkers Prev. 2002; 11(11).
Chen A, Davis BH, Sitrin MD, Brasitus TA, Bissonnette M. Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3).. Am J Physiol Gastrointest Liver Physiol. 2002; 283(4).
Barak N, Wall-Alonso E, Sitrin MD. Evaluation of stress factors and body weight adjustments currently used to estimate energy expenditure in hospitalized patients. JPEN J Parenter Enteral Nutr. 2002; 26(4).
Cao LP, Bolt MJ, Wei M, Sitrin MD, Chun Li Y. Regulation of calbindin-D9k expression by 1,25-dihydroxyvitamin D(3) and parathyroid hormone in mouse primary renal tubular cells.. Arch Biochem Biophys. 2002; 400(1).
Barak N, Ehrenpreis ED, Harrison JR, Sitrin MD. Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations.. Obes Rev. 2002; 3(1).
Li YC, Bolt MJ, Cao LP, Sitrin MD. Effects of vitamin D receptor inactivation on the expression of calbindins and calcium metabolism.. Am J Physiol Endocrinol Metab. 2001; 281(3).
Khare S, Bissonnette M, Wali R, Skarosi S, Boss GR, von Lintig FC, Scaglione-Sewell B, Sitrin MD, Brasitus TA. 1,25-dihydroxyvitamin D3 but not TPA activates PLD in Caco-2 cells via pp60(c-src) and RhoA. Am J Physiol. 1999; 276(4 Pt).
Khare S, Bissonnette M, Scaglione-Sewell B, Wali RK, Sitrin MD, Brasitus TA. 1,25-dihydroxyvitamin D3 and TPA activate phospholipase D in Caco-2 cells: role of PKC-alpha. Am J Physiol. 1999; 276(4 Pt).
Sitrin MD, Bissonnette M, Bolt MJ, Wali R, Khare S, Scaglione-Sewell B, Skarosi S, Brasitus TA. Rapid effects of 1,25(OH)2 vitamin D3 on signal transduction systems in colonic cells. Steroids. 1999; 64(1-2).
Bolt MJ, Mailloux RJ, Rasenick MM, Wali RK, Skarosi S, Bissonnette M, Brasitus TA, Sitrin MD. Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms. Gastroenterology. 1998; 115(6).
Wali RK, Frawley BP, Hartmann S, Roy HK, Khare S, Scaglione-Sewell BA, Earnest DL, Sitrin MD, Brasitus TA, Bissonnette M. Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta. Cancer Res. 1995; 55(22).
Wali RK, Bissonnette M, Khare S, Hart J, Sitrin MD, Brasitus TA. 1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a noncalcemic analogue of 1 alpha,25-dihydroxyvitamin D3, inhibits azoxymethane-induced colonic tumorigenesis. Cancer Res. 1995; 55(14).
Wali RK, Bissonnette M, Jiang K, Niedziela SM, Khare S, Roy HK, Sitrin MD, Brasitus TA. 1,25-Dihydroxyvitamin D3 stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: an effect modulated by vitamin D status. J Cell Physiol. 1995; 162(2).
Khare S, Wilson D, Wali RK, Tien XY, Bissonnette M, Niedziela SM, Bolt MJ, Sitrin MD, Brasitus TA. Guanylin activates rat colonic particulate guanylate cyclase. Biochem Biophys Res Commun. 1994; 203(3).
Bissonnette M, Tien XY, Niedziela SM, Hartmann SC, Frawley BP, Roy HK, Sitrin MD, Perlman RL, Brasitus TA. 1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i. Am J Physiol. 1994; 267(3 Pt).
Khare S, Tien XY, Wilson D, Wali RK, Bissonnette BM, Scaglione-Sewell B, Sitrin MD, Brasitus TA. The role of protein kinase-C alpha in the activation of particulate guanylate cyclase by 1 alpha,25-dihydroxyvitamin D3 in CaCo-2 cells. Endocrinology. 1994; 135(1).
Frawley BP, Tien XY, Hartmann SC, Wali RK, Niedziela SM, Davidson NO, Sitrin MD, Brasitus TA, Bissonnette M. TPA causes divergent responses of Ca(2+)-dependent and Ca(2+)-independent isoforms of PKC in the nuclei of Caco-2 cells. Biochim Biophys Acta. 1994; 1222(2).
Halline AG, Davidson NO, Skarosi SF, Sitrin MD, Tietze C, Alpers DH, Brasitus TA. Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells. Endocrinology. 1994; 134(4).
Khare S, Wilson DM, Tien XY, Dudeja PK, Wali RK, Sitrin MD, Brasitus TA. 1,25-Dihydroxycholecalciferol rapidly activates rat colonic particulate guanylate cyclase via a protein kinase C-dependent mechanism. Endocrinology. 1993; 133(5).
Tien XY, Katnik C, Qasawa BM, Sitrin MD, Nelson DJ, Brasitus TA. Characterization of the 1,25-dihydroxycholecalciferol-stimulated calcium influx pathway in CaCo-2 cells. J Membr Biol. 1993; 136(2).
Tien XY, Brasitus TA, Qasawa BM, Norman AW, Sitrin MD. Effect of 1,25(OH)2D3 and its analogues on membrane phosphoinositide turnover and [Ca2+]i in Caco-2 cells. Am J Physiol. 1993; 265(1 Pt).
Davidson NO, Ifkovits CA, Skarosi SF, Hausman AM, Llor X, Sitrin MD, Montag A, Brasitus TA. Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas. Lab Invest. 1993; 68(6).
Jacoby RF, Bolt MJ, Dolan ME, Otto G, Dudeja P, Sitrin MD, Brasitus TA. Supplemental dietary calcium fails to alter the acute effects of 1,2-dimethylhydrazine on O6-methylguanine, O6-alkylguanine-DNA alkyltransferase and cellular proliferation in the rat colon.. Carcinogenesis. 1993; 14(6).
Bolt MJ, Bissonnette BM, Wali RK, Hartmann SC, Brasitus TA, Sitrin MD. Characterization of phosphoinositide-specific phospholipase C in rat colonocyte membranes. Biochem J. 1993; 292 (.
Heber D, Halsted CH, Brooks CM, Chesney RW, DiGirolamo M, Heimburger DC, Hensrud DD, Mark DA, Sitrin MD, Tillman HH. Biennial survey of physician clinical-nutrition training programs. Am J Clin Nutr. 1993; 57(4).
Wali RK, Baum CL, Bolt MJ, Brasitus TA, Sitrin MD. 1,25-dihydroxyvitamin D3 inhibits Na(+)-H+ exchange by stimulating membrane phosphoinositide turnover and increasing cytosolic calcium in CaCo-2 cells. Endocrinology. 1992; 131(3).
Wali RK, Baum CL, Sitrin MD, Bolt MJ, Dudeja PK, Brasitus TA. Effect of vitamin D status on the rapid actions of 1,25-dihydroxycholecalciferol in rat colonic membranes. Am J Physiol. 1992; 262(6 Pt).
Sitrin MD. Nutrition support in inflammatory bowel disease. Nutr Clin Pract. 1992; 7(2).
Bolt MJ, Jensen WE, Sitrin MD. Metabolism of 25-hydroxyvitamin D3 in rats: low-calcium diet vs. calcitriol infusion. Am J Physiol. 1992; 262(3 Pt).
Teegarden D, Meredith SC, Sitrin MD. Determination of the affinity of vitamin D metabolites to serum vitamin D binding protein using assay employing lipid-coated polystyrene beads. Anal Biochem. 1991; 199(2).
Sitrin MD, Halline AG, Abrahams C, Brasitus TA. Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat. Cancer Res. 1991; 51(20).
Leichtmann GA, Bengoa JM, Bolt MJ, Sitrin MD. Intestinal absorption of cholecalciferol and 25-hydroxycholecalciferol in patients with both Crohn's disease and intestinal resection. Am J Clin Nutr. 1991; 54(3).
Llor X, Jacoby RF, Teng BB, Davidson NO, Sitrin MD, Brasitus TA. K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: effects of supplemental dietary calcium and vitamin D deficiency.. Cancer Res. 1991; 51(16).
Dudeja PK, Wali RK, Klitzke A, Sitrin MD, Brasitus TA. Correction of enhanced Na(+)-H+ exchange of rat small intestinal brush-border membranes in streptozotocin-induced diabetes by insulin or 1,25-dihydroxycholecalciferol. J Clin Invest. 1991; 87(5).
Leichtmann GA, Sitrin MD. Update on trace elements. Compr Ther. 1991; 17(1).
Wali RK, Dudeja PK, Bolt MJ, Sitrin MD, Brasitus TA. Correction of abnormal small intestinal cytosolic protein kinase C activity in streptozotocin-induced diabetes by insulin therapy. Biochem J. 1990; 272(3).
Baum CL, Wali RK, Sitrin MD, Bolt MJ, Brasitus TA. 1,2-Dimethylhydrazine-induced alterations in protein kinase C activity in the rat preneoplastic colon. Cancer Res. 1990; 50(13).
Janghorbani M, Rockway S, Mooers CS, Roberts EM, Ting BT, Sitrin MD. Effect of chronic selenite supplementation on selenium excretion and organ accumulation in rats.. J Nutr. 1990; 120(3).
Brasitus TA, Sitrin MD. Intestinal malabsorption syndromes. Annu Rev Med. 1990; 41.
Bolt MJ, Stellaard F, Sitrin MD, Paumgartner G. Serum unconjugated bile acids in patients with small bowel bacterial overgrowth. Clin Chim Acta. 1989; 181(1).
Wood RJ, Sitrin MD, Rosenberg IH. Effect of phosphorus on endogenous calcium losses during total parenteral nutrition. Am J Clin Nutr. 1988; 48(3).
Kushner RF, Shapir J, Sitrin MD. Endoscopic, radiographic, and clinical response to prolonged bowel rest and home parenteral nutrition in Crohn's disease. JPEN J Parenter Enteral Nutr. 1986; 10(6).
Wood RJ, Sitrin MD, Cusson GJ, Rosenberg IH. Reduction of total parenteral nutrition-induced urinary calcium loss by increasing the phosphorus in the total parenteral nutrition prescription. JPEN J Parenter Enteral Nutr. 1986; 10(2).
Sitrin MD, Pollack KL, Bolt MJ. Intestinal absorption of 1,25-dihydroxyvitamin D3 in the rat. Am J Physiol. 1985; 248(6 Pt).
Rosenberg IH, Bengoa JM, Sitrin MD. Nutritional aspects of inflammatory bowel disease. Annu Rev Nutr. 1985; 5.
Bengoa JM, Hanauer SB, Sitrin MD, Baker AL, Rosenberg IH. Pattern and prognosis of liver function test abnormalities during parenteral nutrition in inflammatory bowel disease. Hepatology. 1985; 5(1).
Wood RJ, Sitrin MD, Rosenberg IH. Calciuria in total parenteral nutrition: effects of amino acids and glucose in rats.. Am J Clin Nutr. 1984; 40(1).
Bengoa JM, Sitrin MD, Meredith S, Kelly SE, Shah N, Baker AL, Rosenberg IH. Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease. Hepatology. 1984; 4(2).
Sitrin MD, Pollack KL, Bolt MJ, Rosenberg IH. Comparison of vitamin D and 25-hydroxyvitamin D absorption in the rat.. Am J Physiol. 1982; 242(4).
Rosenberg IH, Sitrin MD. Screening for fat malabsorption.. Ann Intern Med. 1981; 95(6).
Bolt MJ, Sitrin MD, Favus MJ, Rosenberg IH. Hepatic vitamin D 25-hydroxylase: inhibition by bile duct ligation or bile salts. Hepatology. 1981; 1(5).
Sitrin MD, Bohr DF. Ca and Na interaction in vascular smooth muscle contraction.. Am J Physiol. 1971; 220(4).
Bohr DF, Sitrin MD, Hansen TR. Vascular smooth muscle in experimental hypertension.. Clin Sci. 1971; 40(2).
Bengoa JM, Sitrin MD, Meredith S, Kelly SE, Shah N, Baker AL, Rosenberg IH. Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease.. Hepatology. ; 4(2).
Bengoa JM, Hanauer SB, Sitrin MD, Baker AL, Rosenberg IH. Pattern and prognosis of liver function test abnormalities during parenteral nutrition in inflammatory bowel disease.. Hepatology. ; 5(1).
Barak N, Wall-Alonso E, Cheng A, Sitrin MD. Use of bioelectrical impedance analysis to predict energy expenditure of hospitalized patients receiving nutrition support.. JPEN J Parenter Enteral Nutr. ; 27(1).
Barak N, Wall-Alonso E, Sitrin MD. Evaluation of stress factors and body weight adjustments currently used to estimate energy expenditure in hospitalized patients.. JPEN J Parenter Enteral Nutr. ; 26(4).

See All (73 Total) >

Abstracts:

Yen R., Pomakov, O., Mehboob S, Sitrin MD. Ethnic Differences in Findings on Screening Colonoscopy. (Abstract # S1113). Gastroenterology. 2008; 103(S1).
Hasler, W.L., Rao, S.S., Koch, K.L., Sarosiek, I., McCallum, R, Lackner JM, Parkman, H.P, Chey, W.D., Saad, R.J, Kuo, B., Miller, C., Sitrin MD, Katz LA, Wilding, G.E, Semler, J.R.. Wireless capsule quantification of region-specific gastrocolonic response and sleep inhibition of colon motor activity in unprepared colons of humans with normal colon transit. (published abstract). Gastroenterology. 2008; 134.
Hasler, W.L., Saad, R.J., Rao, S.S., Katz LA, Parkman, H.P., Koch, K.L., McCallum, R., Kuo, B., Sarosiek, I., Sitrin MD, Lackner JM, Wilding, G.E., Miller, C., Semler, J.R., Chey, W.D.. Heightened motor activity measured by a wireless capsule in unprepared colons of patients with complaints of constipation: Relation to colon transit and IBS. (published abstract). Gastroenterology. 2008; 134.
Kloetzer, L., Gaman, A., McCallum, R., Koch, K.L., Sitrin MD, Chey, W.D., Lackner JM, Katz LA, Wilding, G.E., Parkman, H.P., Sarosiek, I., Miller, C., Saad, R.J., Rao, S.S., Semler, J.R., Hasler, W.L., Kuo, B.. Characterization of pressure patterns in distal colonic and rectal motility activity between healthy volunteers and patients with dyssynergic defecation using an ambulatory capsule, SmartPill. (published abstract). Gastroenterology. 2008; 134.
Kloetzer, L., Gaman, A., Napadow, V, McCallum, R., Koch, K., Sitrin MD, Chey, W.D., Lackner JM, Katz LA, Wilding, G.E., Parkman, H.P., Sarosiek, I., Smout, A.,, Hasler, W.L., Semler, J.R., Kuo, B.. Spectral analysis of contractile frequency in the ileum and proximal colon: Characterization of motility patterns using an ambulatory capsule, Smartpill. (published abstract). Gastroenterology. 2008; 134.
Lackner JM, Chey, W.D., Rao, S.S., Hasler, W.L,., Katz LA, Koch, K.L., Kuo, B., Lackner JM, Parkman, H.P., McCallum, R., Miller, C., Sarosiek, I., Semler, J.R., Sitrin MD, Wilding, G.E.. How well does stool form and stool frequency correlate with colonic and whole gut transit in healthy controls and constipated patients? (published abstract). Gastroenterology. 2008; 134.
Raddymasu S., Sarosiek I., Parkman H.P., Koch K.L., Sitrin MD, Wo J.M., Hasler W.L., Katz LA, Chey W.D., Semler J.R., Kuo B., McCallum R.. Non-digestible capsule technology to measure gastric motility – comparison between healthy controls and gastroparetic patients with a normal gastric emptying study. (published abstract). Gastroenterology. 2008; 134.
Yen R., Pomakov O., Abdal-Raheem A., Sitrin MD, Mehboob S. Ethnic Differences in Findings on Screening Colonoscopy. (Abstract # 1196). American J. of Gastro. 2007.
Gaman, A, Hutson, A., Hwang, J., Stevens, K., Koch, K.L., Parkman, H.P., McCallum, R., Chey, W.D., Katz LA, Sitrin MD, Lackner JM, Hasler, W.L., Wo, J., Semler, J.R., Kuo, B.. A non-digestible device discriminates motility patterns with a luminal acidic pH change within the distal small bowel and proximal colon. (published abstract). Gastroenterology. 2007; 132(Sup 2).
Hasler, W.L., Coleski, R., Sarosiek, I., McCallum, R, Kuo, B., Parkman, H.P, Sitrin MD, Lackner JM, Katz LA, Koch, K.L., Wo, J., Chey, W.D, Hutson, A., Semler, J.R.. Colon transit and regional colon motor activity in diabetics with gastroparesis compared to healthy volunteers and diabetics with near normal gastric emptying. (published abstract). Gastroenterology. 2007; 132(2).
Kloetzer, L., Gaman, A., Nojkov, B., Chey, W.D., Hwang, J., Stevens, K., Koch, K.L., Parkman, H.P., McCallum, R., Katz LA, Sitrin MD, Lackner JM, Hasler, W.L., Wo, J., Semler, J.R., Kuo, B.. Complete pH profiling of the gastrointestinal tract in healthy volunteers with an ambulatory pH capsule. (published abstract). Gastroenterology. 2007; 132(Supp).
Parkman, H.P., Hutson, A., Lackner JM, Katz LA, Sitrin MD, Kuo, B., McCallum, R., Chey, W.D., Hasler, W.L., Wo, J., Koch, K.L, Semler, J.R.. Assessment of symptoms associated with delayed gastric emptying of the SmartPill. (published abstract). Neurogastroenterology and Motility. 2007; 19.
Rao, S, Kuo, B., Chey, W.D., DiBaise, J., Katz LA, Koch, K.L., Lackner JM, McCallum, R, Saad, R.J, Selover, K.,, Semler, J.R., Sitrin MD, Wilding, G.E, Parkman, H.P. Investigation of wireless capsule (SmartPill) for colonic transit: A comparative study with radiopaque markers in health and constipation. (published abstract). American Journal of Gastroenterology. 2007; 102(Sup 2).
Rao, S.S.,, Kuo, B., Chey, W.D., DiBaise, J, Katz LA, Koch, K.L., Lackner JM, McCallum, R., Saad, R.J., Selover, K., Semler, J.R., Sitrin MD, Wilding, G.E., Parkman, H.P.. Simultaneous assessment of colonic transit using wireless capsule (SmartPill) and radiopaque markers in healthy subjects and effects of gender. (published abstract). The American Journal of Gastroenterology. 2007; 102(Sup 2).
Rao, S.S, McCallum, R., Parkman, H.P., Koch, K.L., Saad, R.J., Chey, W.D, DiBaise, J., Hutson, A., Semler, J.R., Sitrin MD, Lackner JM, Katz LA, Kuo, B.. A comparative study of SmartPill® and radioopaque markers for the assessment of colonic transit time in humans.(published abstract.). Gastroenterology. 2007; 132(sup 2).
Reddymasu, S, Sarosiek, I., Koch, K.L., Hasler, W.L., Lackner JM, Katz LA, Sitrin MD, Parkman, H.P., Wo, J., Chey, W.D., Semler, J.R., Hwang, J., Kuo, B., McCallum, R.. Non-digestible capsule technology to measure frequency of gastric contractions- comparison between healthy and gastroparetic subjects. (published abstract). Gastroenterology. 2007; 132(Sup 2).
Sarosiek, I., Reddymasu, S., Koch, K.L., Hasler, W.L,, Lackner JM, Katz LA, Sitrin MD, Parkman, H.P., Wo, J., Sarosiek, J, Chey, W.D., Semler, J.R., Kuo, B., McCallum, R.. Relationship between the frequency of gastric contractions and gastric emptying of a non-digestible solid in controls and gastroparetics using SmartPill pressure recording capsule: Its future clinical potential. (published abstract). Gastroenterology. 2007; 132(Sup 2).
Sarosiek, I., Sarosiek, J., Rao, S., Parkman, H.P., Kuo, B., Lackner JM, Katz LA, Sitrin MD, Chey, W.D., Hasler, W.L., DiBaise, J., Wo, J., Koch, K.L., Semler, J.R., McCallum, R.. Comparisons of alimentary tract transit times among normal subjects from two multicenter trials using SmartPill wireless pH/pressure recording capsule: Its clinical implication. (published abstract). The American Journal of Gastroenterology. 2007; 102(Sup 2).
Cheng H., Nasser E., Khawam E., Andersen, V., Sitrin MD. Protein kinase C alpha and p21waf1 expression are increased in the remnant jejunum after ileal resection in the rat. (published abstract). Gastroenterology. 2007; 132.
Bhagat V., Andersen V., Sitrin MD. Role of the vitamin D receptor in vitamin D-mediated calbindin D(9k) expression in Caco-2 cells. (published abstract). Gastroenterology. 2007; 132.
Hasler W.L., Parkman H.L., Hutson A., Chey W.D., Koch K.L., McCallum R.W., Wo J.M., Kuo B., Sitrin MD, Stevens K., Landrigan B., Semler J.R., Coleski R.. Postprandial gastric acids neutralization-reacidification measured with an ingested pH telemetry capsule: correlation with emptying of digestible and indigestible solids. (published abstract). Gastroenterology. 2006; 130.
Rafiq S., Andersen V., Satchidanand K., Graves R., Sitrin MD. Increased sensitivity to carbon tetrachloride hepatotoxicity in the aP2DTA mouse model of acquired lipodystrophy and insulin resistance. (published abstract). Gastroenterology. 2006; 130.
Kuo, B, McCallum, R. W., Kock, K. L., Chey, W. D., Wo, J. M.,, Sitrin MD, Hasler, W.L., Lackner JM, Katz LA, Landrigan, B., Selover, K., Huston, A., Barthel, D., Semler, J., Parkman, H. P.. Smartpill, a novel ambulatory diagnostic test for measuring gastric emptying in health and disease. (published abstract). Gastroenterology. 2006; 130.
Parkman, H. P., Huston, A., Maurer, A. H., Knight, L. C., Kuo, B., Hasler, W. L, Chey, W. D.,, McCallum, R. W., Wo, J. M., Kock, K. L., Sitrin MD, Lackner JM, Semler, J.. Optimizing gastric emptying scintigraphy for the detection of gastroparesis. (published abstract). Gastroenterology. 2006; 130.
Sarosiek, I., Kock, K. L., Selover, K., Kuo, B., Parkman, H. P., Hasler, W. L., Wo, J. M., Sitrin MD, Chey, W. D.,, Lackner JM, D‘Andrea, D., McCallum, R. W.. A new non-scintigraphic method for measuring gastrointestinal transit in gastroparetic patients. (published abstract). Gastroenterology. 2006; 130.
Fayyaz M, Mehboob S, Andersen V., Sitrin MD. Extended Octreotide Suppression test to determine hormone responsiveness in a patient with multiple gastric Carcinoid Tumors.(Abstract # 100). American J. of Gastro. 2005.
Bahadur, S., Sitrin MD, Kuo B., Viazis N., Semler J, Lackner JM. Assessment of upper GI. motility in healthy subjects using ambulant capsule technology. (published abstract). Gastroenterology. 2005; 128(S2).
Kuo B., Urma D., Koch K,, Sitrin MD, Bahadur S., Lackner JM, Katz LA, Chey W., Chund G, Semler, J.R., Parkman H.. Correlation between gastric emptying times of an indigestible capsule and scintigraphic meal. (published abstract). Neurogastroenterology and Motility. 2005; 17.
Urma D., Parkman H., Koch K., Sitrin MD, Bahadur S., Lackner JM, Katz LA, Chey W., Motott J., Semler J.R., Kuro B.. Postprandial small intestinal motility response recording with a wireless capsule technology. (published abstract). Neurogastroenterology and Motility. 2005; 17.
Chung P.Y., Sitrin MD, Te H.S.. Serum hypophosphatemia is associated with hepatic recovery in fulminant hepatic failure. (published abstract.). Gastroenterology. 2002; 122.
Khare S, Wali R., Cerda S., Hart J,, Sitrin MD, Brasitus T., Bissonnette M. Ursodeoxycholic acid and an analogue of vitamin D inhibit COX-2 expression in AOM-induced colonic tumors and in HCA-7 Cells: Roles of C/EBP-? and VEGF. (published abstract). Gastroenterology. 2001; 120(5).
Wali R., Stoiber D., Hart J., Sitrin MD, Brasitus T., Bissonnette M.. Ursodeoxycholic acid inhibits tumor development during both AOM-induced colon tumor initiation and progression. (published abstract). Gastroenterology. 2001; 120(5).
Mustafi R., Cerda S.R., Sitrin MD, Brasitus T.A., Bissonnette M.. Protein kinase C-Zeta (PKC-?) Over-expression in Caco-2 cells inhibits anchorage-dependent and -independent proliferation while enhancing apoptosis. (published abstract). Gastroenterology. 2001; 120(5).
Chen A., Bissonnette M., Sitrin MD, Brasitus T.A.. ERK, and its downstream target, Ets-1, are involved in the 1,25(OH)2D3 -induced inhibition of cell growth and stimulation of apoptosis in Caco-2 cells. (published abstract). Gastroenterology. 2001; 120(5).
Samuel S., Alawneh A., Sitrin MD. HRP 12, the murine member of the highly conserved by enigmatic YERO57c/Yjgf/UK114 family, interacts with mitochondrial and secreted liver proteins in the yeast-based two-hybrid system. (published abstract). Gastroenterology. 2000; 134.
Sitrin MD, Berkelhammer C.H., Vereault D.V.. Comparison of the calciuretic effect of methionine and Na2SO4 in the rat. (published abstract). Clinical Research. 1987; 35.
Sitrin MD, Bolt M.J.G., Ford H.. Mechanism of transport of vitamin D3 palmitate in plasma. (published abstract). Clinical Research. 1987; 35.
Berkelhammer C.H., Wood R.J., Rosenberg I.H., Sitrin MD. Mechanism for reduction of TPN induced hypercalciuria by phosphate: Evidence against the role of parathyroid hormone. (published abstract). Journal of Parenteral and Enteral Nutrition. 1987; 11.
Teegarden D., Meredith S.C., Sitrin MD. Modeling of 25 hydroxyvitamin D binding to rat serum vitamin D binding protein. (published abstract). Federation Proceedings. 1987; 46.
Schraut W.H., Lee K.K.W., Sitrin MD, Moynihan H.L.. A comparison of the outcome after end to end vs. end to side ileo colonic anastomosis. (published abstract). Association for Acad Surgery. 1986.
Schraut W.H., Lee K.K.W., Sitrin MD. Recipient growth and nutritional status following transplantation of segmental small bowel allografts. (published abstract). Association for Acad Surgery. 1986.
Wood R.J., Sitrin MD, Rosenberg I.H.. Effect of phosphate on urinary calcium excretion in normal and thyroparathyroidectomized rats receiving total parenteral nutrition. (published abstract.). Clinical Research. 1986; 34.
Berkelhammer C.H., Wood R.J., Rosenberg I.H., Sitrin MD. Alkalinization with acetate reduces hypercalciuria during total parenteral nutrition. (published abstract). Clinical Research. 1986; 34.
Sitrin MD. Hepatic histology in long term total parenteral nutrition (TPN). (published abstract). Gastroenterology. 1986; 90.
Teegarden D., Meredith S.C., Sitrin MD. Partial purification of rat enterocyte cytosolic 25 hydroxyvitamin D (25 OHD) binding protein. (published abstract). Federation Proceedings. 1986; 45.
Schraut W.H., Lee K.K.W., Sitrin MD. Small bowel transplantation in the young rat permitting normal growth and maturation. (published abstract). ESSR. 1986.
Wood R.J., Sitrin MD, Cusson G.J., Rosenberg I.H.. Urinary calcium loss during total parenteral nutrition: effect of phosphorus. (published abstract). American Society for Bone and Mineral Research. 1985.
Sitrin MD, Jensen W.E.. Transfer of vitamin D metabolites and other fat soluble vitamins from chylomicrons to serum. (published abstract). Clinical Research. 1985; 33.
Hanauer S.B., Sitrin MD, Bengoa JB, Newcomb S.A., Kirsner J.B.. Long term follow up of patients with Crohn's disease treated by supportive total parenteral nutrition. (published abstract). Gastroenterology. 1984; 86.
Kushner R.F., Cusson G.J., Smith M.W., Walker J.G., Sitrin MD. Treatment of selected patients with active Crohn's disease by prolonged bowel rest and home parenteral nutrition (HPN. (published abstract). Gastroenterology. 1984; 86(5).
Bolt M.J.G., Sitrin MD. Elevated fasting and postprandial unconjugated serum bile acids in small bowel bacterial overgrowth. (published abstract). Gastroenterology. 1983; 84.
Sitrin MD, Jensen W.E., Lieberman F., Addington W.. Reversible neurologic disease caused by vitamin E deficiency in an adult with cystic fibrosis. (published abstract). Gastroenterology. 1983; 84.
Bengoa J.M., Sitrin MD, Rosenberg I.H.. Comparison of vitamin D and 25 hydroxyvitamin D absorption in patients with chronic cholestatic liver disease. (published abstract). Gastroenterology. 1983; 84.
Wood R.J., Sitrin MD, Rosenberg I.H.. Amino acid induced hypercalciuria in rats receiving total parenteral nutrition (TPN). (published abstract). FASEB. 1983.
Klein F.S., Sitrin MD, Lawler M., Lin C.C.. The effect of total parenteral nutrition (TPN) on the outcome of pregnancy. (published abstract). American Dietetic Association. 1983.
Lieberman F., Noronha A., Sitrin MD. Reversal of ophthalmoplegia in cystic fibrosis after prolonged high dose parenteral vitamin E therapy. (published abstract). ANN. 1983.
Bengoa J.M., Sitrin MD, Wood R.J., Rosenberg I.H.. Amino acid induced hypercalciuria during total parenteral nutrition (TPN). (published abstract). Clinical Research. 1983; 31.
Wood R.J., Bengoa J.M., Sitrin MD, Rosenberg I.H.. Increased urinary losses of calcium, phosphorus and magnesium in patients receiving cyclic versus continuous total parenteral nutrition. (published abstract). Clinical Research. 1983; 31.
Bengoa J.M., Sitrin MD, Kelly S., et al.. Serum 25 hydroxyvitamin D, calcium absorption and bone histology in chronic cholestatic liver disease. (published abstract). Clinical Research. 1982; 30.
Bengoa J.M., Hanauer M.D., Sitrin MD, et al.. Pattern and prognosis of hepatic dysfunction during parenteral nutrition (PN) in inflammatory bowel disease (IBD. (published abstract). Gastroenterology. 1982; 82.
Hanauer S.B., Bengoa J.M., Sitrin MD, Rosenberg I.H.. Influence of fistula, perianal disease and obstruction on response of patients with Crohn's disease (CD) to parenteral nutrition (PN) and bowel rest (BR). (published abstract). Gastroenterology. 1982; 82.
Sitrin MD, Schoeller D.A., van Santen E., et al.. Development of a protein absorption test using a stable isotope labeled protein. (published abstract). Gastroenterology. 1982; 82.
Pollack K.L., Sitrin MD, Rosenberg I.H.. Chylomicron dependent absorption and transport of vitamin D (D) and 25 hydroxyvitamin D (25 OHD) in the rat. (published abstract). Clinical Research. 1981; 29.
Sitrin MD, Pollack K.L., Rosenberg I.H.. Influence of bile salts and fat on intestinal absorption of vitamin D (D) and 25 hydroxyvitamin D (25 OHD) in the rat. (published abstract). Clinical Research. 1981; 29.
Sitrin MD, Pollack K.L., Rosenberg I.H.. Intestinal absorption of 1,25 (OH)2 in the rat. (pubished abstract). Gastroenterology. 1981; 80.
Kelly S., Sellin J.H,, Meredith S.C., Sitrin MD, et al.. Calcium absorption, vitamin D status and bone disease after bowel resection for Crohn's disease. (published abstract). Gastroenterology. 1980; 78.
Sitrin MD, et al.. Comparison of vitamin D (D) and 25 OH vitamin D (25 OH D) absorption in the rat. (published abstract). Gastroenterology. 1980; 78.
Sitrin MD, Bolt M.J.G., Rosenberg I.H.. Characterization and quantitative analysis of the biliary excretion products of vitamin D and 25-OH vitamin D (25-OH D). (published abstract). Clinical Research. 1978; 26.
Sitrin MD, Bolt M.J.G., Rosenberg I.H.. Enterohepatic circulation of water soluble metabolites of 25 OH vitamin D. (published abstract). Gastroenterology. 1978; 74.
Rabb J., Sellin J.H., Sitrin MD, et al.. Reduction of urinary calcium oxalate activity product ratio by dietary calcium in Crohn‘s disease. (published abstract). Gastroenterology. 1978; 76.
Bolt MJ, Sitrin MD, Favus MJ, Rosenberg IH. Hepatic vitamin D 25-hydroxylase: inhibition by bile duct ligation or bile salts. (published abstract). Clinical Research. 1977; 25.
Yen, R., Pomakov O.A., Sitrin MD. Relationship of proximal hyperplastic polyps to adenomas on screening colonoscopy. (published abstract). Gastroenterology. ; 134.

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VA WNY Healthcare System
3495 Bailey Avenue
Buffalo, NY 14214
Phone: (716) 834-9200
Email: mdsitrin@buffalo.edu

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Michael D. Sitrin MD

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