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Mandip                         Panesar

Mandip Panesar MD

Department of Medicine

Clinical Associate Professor of Medicine

Specialty/Research Focus

Nephrology

 
Professional Summary:

I am the medical director of the hemodialysis program at Erie County Medical Center (ECMC). In this role, I am involved in all aspects of patient care, safety and quality. I also have an active outpatient practice and care for patients with chronic kidney disease (CKD), glomerulonephritis, hypertension, polycystic kidney disease, electrolyte abnormalities, anemia, secondary hyperparathyroidism and end-stage renal disease (ESRD).

My clinical research is in two main areas: mechanisms of, and treatment options for anemia; and acid base disturbances in ESRD hemodialysis patients. In collaboration with UB’s Department of Pharmaceutical Sciences, I am involved in translational research investigating the mechanisms, risk factors and pathophysiology of erythropoietin dosing and resistance in ESRD patients.

I am interested as well in understanding the development of metabolic alkalosis in patients with ESRD and the condition’s correlation to the risk of sudden cardiac death. I am conducting a clinical study investigating changes in bicarbonate levels post-hemodialysis using various concentrations of Fresenius’ Naturalyte bicarbonate/acetate dialysate and the effects on arrhythmias and cardiovascular hemodynamics.

My involvement in clinical informatics includes serving as an adjunct faculty member and site program director for UB’s ACGME-accredited clinical informatics fellowship program. In this role, I provide medical leadership by assisting physicians in the delivery of patient care, medical education and research, and advancing clinical quality and safety initiatives through the use of clinical information systems. I am currently involved in projects studying methods to increase interoperability of electronic health records across hospital systems, optimizing dialysis-specific electronic health records and developing methods and procedures to reduce copying and pasting in medical documentation.

I supervise nephrology fellows and internal medicine residents during their rotations in the inpatient nephrology consultation services at ECMC.

Education and Training:
  • Fellowship, Chief Nephrology Fellow, University of Arkansas (2006)
  • Fellowship, Nephrology, University of Arkansas (2005)
  • Residency, Internal Medicine, Associate Chief Resident, St. Francis Medical Center - Seton Hall University (2004)
  • Residency, Internal Medicine, St. Francis Medical Center - Seton Hall University (2002)
  • MD, St. George‘s University (2000)
  • MS, Physiology, McGill University (1996)
  • BS, Physiology, McGill University (1994)
  • Dipl, Health Sciences, Marianopolis College (1991)
Employment:
  • Chief Medical Information Officer, Erie County Medical Center (2015-present)
  • Clinical Associate Professor of Medicine, Medicine, University at Buffalo (2013-present)
  • Medical Director, Hemodialysis, Erie County Medical Center (2009-present)
  • Clinical Assistant Professor of Medicine, Medicine, University at Buffalo (2006–2013)
Awards and Honors:
  • Fellow, American Society of Nephrology (2010)
  • Award of Excellence, Erie County Medical Center (2008)
  • Resident of the Year Award (Research), St. Francis Medical Center (2004)
  • Resident of the Year Award, St. Francis Medical Center (2003)
  • International Peace Scholarship, St. George University (2000)

Research Expertise:
  • Anemia management in end-stage renal disease (ESRD)
  • Arrhythmias in chronic and end-stage renal disease (ESRD)
  • Clinical informatics
  • Experimental nephrogenic systemic fibrosis
  • Principal investigator: BAY 85-3934 / 16209 DIALOGUE: Daily oral treatment increasing endogenous erythropoietin. A randomized, parallel group, open-label, multicenter study to investigate the efficacy and safety of oral BAY 85-394 and active comparator (epoetin alfa/beta) in the maintenance treatment of subjects with anemia associated with chronic kidney disease who are on dialysis and on treatment with erythropoiesis-stimulating agent in the United States and Japan
  • Principal investigator: BAY 85-3934 / 16208 A randomized, parallel group, open-label, multicenter study to investigate the efficacy and safety of oral BAY 85-3934 and active comparator (epoetin alfa / beta) in the maintenance treatment of subjects with anemia associated with chronic kidney disease who are on dialysis and on treatment with an erythropoiesis stimulating agent in the United States and Japan
  • Sub-Investigator: Protocol # 156-04-251 A Phase 3, Multi-center, Double-blind, Placebo-controlled, Parallel-arm Trial to Determine Long-term Safety and Efficacy of Oral Tolvaptan Tablet Regimens in Adult Subjects with Autosomal Dominant Polycystic Kidney Disease
  • Sub-Investigator: Protocol # 156-08-271 Multi-Center, Open-label, Extension Study to Evaluate the Long-Term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects with Autosomal Dominant Poplycystic Kidney Disease
  • Sub-investigator: Protocol #156-09-290 A Phase 2, Multicenter, Randomized, Placebo-controlled, Double-blind, Placebo-masked, Parallel-group Pilot Trial to Compare the Efficacy, Tolerability, and Safety of Tolvaptan Modified-release and Immediate-release Formulations in Subjects with Autosomal Dominant Polycystic Kidney
  • Sub-investigator: Protocol #156-10-291 A Multi-center, Longitudinal, Observational Study of Patients with Autosomal Dominant Polycystic Kidney Disease to Establish the Rate, Characteristics, and Determinants of Disease Progression

Journal Articles:
See all (4 more)

Professional Memberships:
  • National Kidney Foundation
  • Northeast Kidney Foundation
  • American Society of Nephrology
Presentations:
  • "Getting ready for MACRA: What does it mean for Nephrology?" Nephrology Lecture Series, Division of Nephrology (2016)
  • "Calcium/ Phosphorus Regulation in Chronic Kidney Disease" Medicine Grand Rounds (2013)
  • "Do Low Iron Stores Prevent NSF?" 5th Annual Symposium on Nephrogenic Systemic Fibrosis and Allied Fibrosing Disorders, Yale University (2011)
  • "Chronic Kidney Disease" Medicine Grand Rounds, WCA Hospital (2010)
  • "Nephrogenic Systemic Fibrosis" Medicine Grand Rounds, Buffalo General Medical Center (2010)
  • "Combined effects of iron and gadolinium as a risk factor in the development of nephrogenic systemic fibrosis" National Kidney Foundation (2008)
  • "Clinical and pathological features of Nephrogenic Fiborsing Dermopathy: Improvement after kidney transplatation in three patients." American Society of Nephrology Kidney Week (2005)
Service Activities:
  • Practitioner Health Advisory Committee - ECMC; Co-Chair (2014–present)
  • Editorial Board, Clinical Journal of the American Society of Nephrology (CJASN); Board Member (2013–2016)
  • Advisory Board, Northeast Kidney Foundation; Board Member (2013–2015)
  • Medical Advisory Board, Northeast Kidney Foundation; Board Member (2013)
  • Board of Directors, Health in Erie County; Board of Directors (2013–present)
  • Medical Executive Committee, Erie County Medical Center; Member (2013–present)
  • Section Editor, Dialysis & Transplantation; Editor (2010–2011)
  • Board Member, National Kidney Foundation of Western New York; Board Member (2009–2011)
  • Editorial Advisory Board, Dialysis & Transplantation; Board Member (2005–2011)

School News:
In the Media:

Clinical Specialties:
Clinical Offices:
Insurance Accepted:


Contact Information

Erie County Medical Center
462 Grider Street
Buffalo, NY 14215
Phone: (716) 898-4803
Email: mpanesar@buffalo.edu

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