Oscar A. deLeon-Casasola MD
Oscar A. deLeon-Casasola
MD
Professional Summary:
Program Director, UB Anesthesiology Pain Management Fellowship
Education and Training:
- Residency, Anesthesiology, University at Buffalo (1990)
- Residency, Critical Care track, Downstate Medical Center (1987)
- Internship, General Surgery, Downstate Medical Center (1986)
- Residency, General Surgery, Military Hospital (1983)
- Internship, Military Hospital (1982)
- MD, Universidad de San Carlos de Guatemala (1982)
Employment:
- Professor, Oncology, Roswell Park Cancer Institute (2006-present)
- Professor with Tenure, Anesthesiology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2001-present)
- Chief, Pain Medicine and Symptom Management, Roswell Park Cancer Institute (1999-present)
- Director, Anesthesia Research, Roswell Park Cancer Institute (1998-present)
- Anesthesiologist, Roswell Park Cancer Institute (1990-present)
- Associate Professor, Anesthesiology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (1996–2001)
- Chief, Critical Care Medicine, Roswell Park Cancer Institute (1994–1998)
- Assistant Professor, Anesthesiology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (1991–1996)
- Director, Surgical Intensive Care Unit, Roswell Park Cancer Institute (1993–1994)
- Director of the Acute Pain Service, Roswell Park Cancer Institute (1991–1993)
- Instructor, Anesthesiology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (1990–1991)
Awards and Honors:
- Castle Connolly Medical List of America's Top Doctors (2011)
- Top Doctors List (2011)
- Top Doctors List (2010)
- Best Dctors in America (2009)
- Who's Who Among Executives and Professionals in Medicine and Healthcare (2007)
- ESRA Distinguished Service Award (2007)
- M/Pfizer Visiting Professorship in Pain Medicine (2006)
- 100 Top Docs in Buffalo (2006)
- America's Top Doctors (2006)
- America's Top Doctors for Cancer (2006)
- America's Top Doctors (2005)
- Empire Who‘s Who Among Executives and Professional in Healthcare and Medicine (2005)
- Chair, Scientific Committee (2004)
Grants and Sponsored Research:
- January 2002
Cancer Pain Education in the Community
Janssen Laboratories
Role: Co-Investigator - January 2001
A Multi-Modal Rehabilitation Program for Patients Undergoing Radical Prostatectomies
Astra Zeneca
Role: Co-Investigator - January 2001
A Multi-Modal Rehabilitation Program for Patients Undergoing Radical Prostatectomies
Roxane Laboratories Research Grant
Role: Co-Investigator
Journal Articles:
- deLeon-Casasola OA, Mayoral V. (2016) The Topical 5% lidocaine medicated plaster in localized neuropathic pain: a reappraisal of the clinical evidence. Journal of Pain Research (Jan), 9: 67-79.
- Chou R, Gordon DB, deLeon-Casasola OA, Rosenberg JM. (2016) Management of Postoperative Pain: A Clinical Practice Guideline from the American Pain Society, American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committe. Journal of Pain (Jan), 17: 131-157.
- deLeon-Casasola OA. (2016) Interventional Management of Head and Face Pain. Anesthesiology 2016 (Jan), 124(515).
- Nalamachu S, deLeon-Casasola OA, Robinson CY, Galer BS, Gould E, Gammaitoni A. (2015) An Analysis of Rescue Medication Utilization from a 3-Month, Randomized, Double-Blind, Placebo-Controlled Study in Patients with Chronic Low Back Pain Treated with Single-Entity, Twice-Daily, Extended-Release Hydrocodone. Pain Med (Dec), 16(12): 2338-2343.
- Gordon DB, deLeon-Casasola OA, Wu CL, Sluka K, Brennan T, Chou R. (2015) Research Gaps on Practice Guidelines for Acute Postoperative Pain Management in Adults: Findings from a Review of the Evidence for an American Pain Society Clinical Practice Guideline. J Pain (Dec).
- Swarm R, Abernethy AP, Anghelescu DL, Benedetti C, Blinderman CD, Boston B, Cleeland C, Coyle N, Deleon-Casasola OA, Eilers JG, Ferrell B, Janjan NA, Karver SB, Levy MH, Lynch M, Moryl N, Murphy BA, Nesbit SA, Oakes L, Obbens EA, Paice JA, Rabow MW, Syrjala KL, Urba S, Weinstein SM. (2010) Adult cancer pain. J Natl Compr Canc Netw (Sep), 8(9): 1046-1086.
- de Leon-Casasola OA, deLeon-Casasola OA. (2009) Spinal cord and peripheral nerve stimulation techniques for neuropathic pain. J Pain Symptom Manage (Aug), 38(2 Sup): 28-38.
- deLeon-Casasola OA. (2009) Spinal Cord and Peripheral Nerve Stimulatoin Techniques for Neuropathic Pain. J Pain and Symptom Mgmt (Jan), 38(2S): S28-S38.
- de Leon-Casasola OA, deLeon-Casasola OA. (2008) Current developments in opioid therapy for management of cancer pain. Clin J Pain (May), 24 Su: 3-7.
- deLeon-Casasola OA. (2008) Implementing Therapy with Opioids in Patients with Cancer. Oncology Nursing Forum (Jan), 35(6): S1-S6.
- de Leon-Casasola OA, deLeon-Casasola OA. (2007) Multimodal approaches to the management of neuropathic pain: the role of topical analgesia. J Pain Symptom Manage (Mar), 33(3): 356-364.
- De Andres J, Valia JC, Cerda-Olmedo G, Quiroz C, Villanueva V, Martinez-Sanjuan V, deLeon-Casasola OA. (2007) Magnetic Resonance Imaging in Patients with Spinal Neurostimulation Systems. Anesthesiology 2007 (Jan), 106: 776-786.
- Reina MA, deLeon-Casasola OA, Villanueva MC, et al. (2004) Ultrastructural Findings in Human Spinal Pia Mater in Relation to Subarachnoid Anesthesia. Anesthesia and Analgesia (Jan), 98: 1479-1485.
- Vallejo R, deLeon-Casasola OA, Benyamin R. (2004) Opioid Therapy and Immunosuppression: A Review. American Journal of Therapeutics (Jan), 11: 1-12.
- deLeon-Casasola OA. (2004) Interventional Procedures for Cancer Pain Management: When are they indicated?. Cancer Investigation (Jan), 22: 630-642.
- deLeon-Casasola OA. (2003) Using a Multi-Modal Rehabilitation Program for Patients Undergoing Open Simoidectomy. Surgical Technology International (Jan)49-52.
- de Leon-Casasola OA, deLeon-Casasola OA. (2002) Cellular mechanisms of opioid tolerance and the clinical approach to the opioid tolerant patient in the post-operative period. Best Pract Res Clin Anaesthesiol (Dec), 16(4): 521-525.
- de Leon-Casasola OA, deLeon-Casasola OA. (2002) Using a multi-modal rehabilitation program for patients undergoing open sigmoidectomy. Surg Technol Int (Sep), 10: 49-52.
- deLeon-Casasola OA. (2002) How should I treat Regractory Metastatic Cancer Pain?. International Monitor on Regional Anesthesia and Pain Therapy (Jan), 13(4): 3-6.
- Chaparro LE, Santos X, deLeon-Casasola OA. (2002) The Effects of Perioperative Epidural Techniques on the Incidence of Postoperative Complications: Analysis of Conflicting Results. Revista Argentina de Anestesiologia (Jan), 60: 299-308.
- Reima MA, deLeon-Casasola OA. (2002) The Origin of the Spinal Subdural Space: Ultrastructure Findings. Anesthesia and Analgesia (Jan), 94: 991-995.
- Reina MA, Lopez A, Machas F, deLeon-Casasola OA, de Andres JA. (2002) Electron Microscopy and the Expansion of Regional Anesthesia Knowledge Techniques. Regional Anesthesia and Pain Management (Jan), 6: 165-171.
- de Médicis E, de Leon-Casasola OA, deLeon-Casasola OA. (2001) Reversible paraplegia associated with lumbar epidural analgesia and thoracic vertebral metastasis. Anesth Analg (May), 92(5): 1316-1318.
- Reina MA, de Leon-Casasola OA, Lopez A, De Andres J, Martin S, Mora M, deLeon-Casasola OA. (2000) An in vitro study of dural lesions produced by 25-gauge Quincke and Whitacre needles evaluated by scanning electron microscopy. Reg Anesth Pain Med (Jul), 25(4): 393-402.
- de Leon-Casasola OA, deLeon-Casasola OA. (2000) Critical evaluation of chemical neurolysis of the sympathetic axis for cancer pain. Cancer Control (Mar), 7(2): 142-148.
- Magimbi AS, deLeon-Casasola OA. (2000) Spinal Cord Stimulation. Techniques in Regional Anesthesia and Pain Management (Jan), 4: 132-136.
- deLeon-Casasola OA, Rom S. (2000) Thoracic Epidural Anesthesia and Analgesia for Cancer Surgery: The Importamce of the Anesthetic Technique. Techniques in Regional Anesthesia and Pain Management (Jan), 4: 69-76.
- deLeon-Casasola OA. (2000) Thoracic Epidural Anesthesia and Analgesia for Colon Cancer Surgery: A Multimodal Approach to Favor Early Hospital Discharge. Argentinian Society of Anesthesiology (Jan), 58: 25-29.
- deLeon-Casasola OA, Yarussi AT. (2000) Physiopathology of Opioid Tolerance and Clinical Approach to the Opioid Tolerant Patient. Current Review in Pain (Jan), 4: 2503-205.
- Yarussi AT, Sands RP, Edge SB, Lema MJ, deLeon-Casasola OA. (1999) Peripheral Morphine Analgesia for Postoperative Pain Following Axillary Node Dissection for Breast Cancer: A Controlled Randomized Double-Blind Study. Regional Anesthesia (Jan), 24: 142-145.
- deLeon-Casasola OA. (1999) Neurolytic Blocks of the Sympathetic Axis for the Treatment of Visceral Pain in Cancer. Current Reveiw of Pain (Jan), 3: 173-177.
- Yarussi A, Sands R, Edge SB, Lema MJ, DeLeon-Casasola OA. (1999) Evaluation of Peripheral Morphine Analgesia for Lumpectomy and Axillary Node Dissection: A Randomized, Double-Blinded Placebo-Controlled Study. Regional Anesthesia and Pain Medicine (Jan), 24(2): 142-145.
- Sands RP, Yarussi AT, deLeon-Casasola OA. (1998) Complications and Side Effects Associated with Epidural Bupivacaine/Morphine Analgesia. Acute Pain (Jan), 1: 43-50.
- de Leon-Casasola OA, deLeon-Casasola OA. (1996) New concepts in postoperative pain management: is there more beyond pain control?. J Fla Med Assoc (Dec), 83(10): 695-700.
- de Leon-Casasola OA, deLeon-Casasola OA. (1996) Postoperative pain management in opioid-tolerant patients. Reg Anesth (Nov), 21(6 Sup): 114-116.
- de Leon-Casasola OA, deLeon-Casasola OA. (1996) Clinical outcome after epidural anesthesia and analgesia in high-risk surgical patients. Reg Anesth (Nov), 21(6 Sup): 144-148.
- de Leon-Casasola OA, deLeon-Casasola OA. (1996) Immunomodulation and epidural anesthesia and analgesia. Reg Anesth (Nov), 21(6 Sup): 24-25.
- de Leon-Casasola OA, deLeon-Casasola OA. (1996) Verification of sensory block during regional anesthesia. Reg Anesth (Nov), 21(6 Sup): 126-128.
- deLeon-Casasola OA, Lema MJ. (1992) Postoperative Pain Management in Patients with Opioid Dependency. The Solution (Dec).
- deLeon-Casasola OA, Lema MJ. (1992) Establishing an acute postoperative pain service. Roswell Park Journal (Jan), 3(1): 6-7.
- Eldohiri S, Deleon OA, Lovrincevic M. (1900) Spinal Cord simulation for the treatment of brachial plexopathy, post-mastectomy lymphedema and post-mastectomy pain syndrome. Anesthesia Analgesia (Jan).
Books and Book Chapters:
- Hitt JM and deLeon OA. (2013) Complications in Regional Anesthesia & Pain Medicine, 2nd ed. In: Complications associated with Superior Hypogastric and Ganglion Impar Blocks. Lippincott Williams & Wilkins
- deLeon-Casasola OA. (2010) Maual Practico de Dolor Neuropatico. In: Topical Analgesia for Neuropathic Pain. Elsevier Espana, 167-176.
- Urie B, deLeon-Casasola OA. (2009) Acute Pain Management. In: Pharmacokinetics of Epidural Opioids. Cambridge University Press, 102-108.
- Sinatra RS, deLeon-Casasola OA, Ginsberg B, Viscusi ER. (2009) Acute Pain Management. Cambridge University Press.
- deLeon-Casasola OA, Yarussi AT. (2008) Practical Management of Pain, 4th ed. In: Cancer Pain. Mosby/Elsevier, 413-426.
- deLeon-Casasola OA. (2008) Raj's Practical Management of Pain 4th ed. In: Neurolysis of the Sympathetic Axis for Cancer Pain Management. Mosby/Elsevier, 917-926.
- Deschner C, Allen M, deLeon-Casasola OA. (2007) Textbook of Regional Anesthesia and Acute Pain Management. In: Epidural Blockade. McGraw Hill Medical, 229-267.
- deLeon-Casasola OA. (2007) Complications in Regional Anesthesia & Pain Medicine, 1st ed. In: Complications Associated with Superior Hypogastric and Ganglion Impar Blocks. Sunders/Elsevier, 221-226.
- deLeon-Casasola OA. (2006) Cancer Pain -- Pharmacological, Interventional, and Palliative Care Approaches. Saunders Elsevier.
- deLeon-Casasola OA. (2006) Cancer Pain: Pharmacological, Interventional and Palliative Care Approaches, 1st Ed. In: Cancer Pain Management in the Opioid Tolerant Patient. Sunders/Elsevier, 231-234.
- De Medicis E, deLeon-Casasola OA. (2005) Ambulatory Anesthesia -- Perioperative Analgesia 1st Ed. In: Local Anesthetic Toxicity in the Ambulatory Setting. McGraw Hill, 207-213.
- Deleon-Casasola OA, O‘Leary KA. (1995) Handbook of Gynecologic Oncology, 2nd ed. In: The gynecology-oncology patient in the intensive care unit. Little, Brown and Co.
Abstracts:
- Sands R, deLeon-Casasola OA, Harrison P, Velagapudi S, Lema MJ. (1995) Epidural fentanyl action, like intravenous fentanyl, occurs primarily at the supraspinal level. Reg Anesth, (Jan) 40
- Plancarte R, deLeon-Casasola OA, Lema MJ. (1995) Alternative approaches for super hypogastric plexus block. Reg Anesth, (Jan) 90
- deLeon-Casasola OA, Plancarte R, Lema MJ. (1995) Neurolytic superior hypogastric plexus block for cancer pain. Anesthesiology, (Jan) A843
- Plancarte R, deLeon-Casasola OA, Allende S, Lema MJ. (1995) The clinical effectiveness of two alternative aproaches for neurolytic superior hypogastric plexus blocks in patients with pelvic pain associated with extensive retroperitoneal cancer. Reg Anesth, (Jan) 90
- O'Leary KA, deLeon-Casasola OA, Lema MJ. (1995) The use of thoracic epidural anesthesia with sedatin for post-surgica bronchopleural fistula repair. Reg Anesth, (Jan) 100
- O'Leary KA, deLeon-Casasola OA, Lema MJ. (1995) Thoracic epidural anesthesia for the repair of bronchopleural fistulas. Reg Anesth, (Jan) 100
- Nader-Djalal N, deLeon-Casasola OA, Peer GL, Vladutiu AO, Lema MJ. (1994) Pre-operative levels of B-endorphin and Met-enkephalin and the Duration of Analgesia after TURP under Spinal Anesthesia. Anesthesiology, (Jan) A1056
- Deleon-Casasola OA, McClintick EA, Harrison P, Massey J, Lema MJ. (1993) The addition of intramuscular ketorolac to epidural morphine-bupivicaine for post-thoracotomy analgesia. Regional Anesthesia, (Jan) 74-74
- deLeon-Casasola OA, Karabella D, Lema MJ. (1993) The effects of epidural bupivacaine-morphine and intravenous PCA morphine on bowel function and pain after radical hysterectomies. Anesth Analg, (Jan) S73
- deLeon-Casasola OA, Kirch D, Karas P, Syed N, Blumenson L, Lema MJ. (1993) The influence of birth weight and oxytocin in the quality of epidural analgesia durig labor. Anesth Analg, (Jan) S74
- deLeon-Casasola OA, McClintick E, Harrison P, Massey J, Lema MJ. (1993) Epidural morphone-bupivacaine and ketorolac versus epidural morphine-bupivacaine for post-thoracotomy analgesia. Reg Anesth, (Jan) 74
- deLeon-Casasola OA, Karabella D, Harrison P, Lema MJ. (1993) A decrease in postoperative myocardial ischemia and infarction by epidural bupivacaine-morphine after upper abdominal surgery. Reg Anesth, (Jan) 66
- Bacon DR, deLeon-Casasola OA, Lema MJ. (1993) Society Seals: Symbls of Organized Anesthesia. Anesthesiology, (Jan) A1029
- Bacon DR, deLeon-Casasola OA, Myers DP, Peppriell JE, Lema MJ. (1993) Minutes of the American Society of Regional Anesthesia 1924-1939. Anethesiology, (Jan) A1028
- deLeon-Casasola OA, Kirch D, Karas P, Syed N, Blumenson L, Lema MJ. (1992) Comparison of epidural bupivacaine-fentanyl and bupivacaine-sufentanil infusions for relieving labor pain. Reg Anesth, (Jan) 39
- Kent E, deLeon-Casasola OA, Lema MJ. (1992) Neurolytic Superior Hypogastric Plexus Block for Cancer Related Pelvic Pain. Reg Anesth, (Jan) 39
- deLeon-Casasola OA, Parker B, Schwartz C, Bacon DR, Myers DP, Peppriell J, Orsini L, Lema MJ. (1992) Postoperative epidural analgesia decreases length of hospitalization and intensive care unit stays in high-risk surgical cancer patients. Anesthesiology, (Jan) A899
- deLeon-Casasola OA, Lema MJ. (1992) Epidural sufentanil provides superior analgesia for opioid-tolerant patients unresponsive to epidural morphine. Anesthesiology, (Jan) A855
- deLeon-Casasola OA, Parker B, Myers DP, Bacon DR, Peppriell J, Harrison P, Kent E, Rempel J, Lema MJ. (1992) Experience using epidural bupivacaine-morphine infusions for postoperative analgesia in 2,843 cancer surgical patients. Anesthesiology, (Jan) A856
- deLeon-Casasola, OA, Myeers DP, Doniparthi S, Bacon DR, Peppriell J, Rempel J, Lema MJ. (1991) Postoperative epidural analgesia fo chronic cancer patients taking oral narcotics. Anesthesiology, (Jan) A665
- deLeon-Casasola OA, Myers DP, Rempel J, Bacon DR, Peppriell J, Lema MJ. (1991) A prospective analysis of epidural catheter migration in 1598 cancer surgical patients. Anesthesiology, (Jan) A730
Presentations:
- "Breakthrough Pain: Physiopathology, Opioids in Neuropathic Pain" Meeting; Spanish Society of Pain Medicine (2010)
- "Chronic Opioids for Non-Cancer Pain: The Good, The Bad, and The Ugly, What is New in Neuropathic Pain Therapy" Meeting; Argentine Society of Pain (2010)
- "Chronic Pain in the Cancer Survivor" Annual Meeting; American Society of Regional Anesthesia and Pain Medicine (2010)
- "Multi-modal Analgesic Therapy in the Postoperative Period" ; SAMBA (2010)
- "Pharmacological Management for Cancer Pain, Interventional Procedures for Cancer Pain" Annual Meeting; American Academy of Pain Medicine (2010)
- "Pharmacological Therapy for Cancer Pain" ; APS (2010)
- "Post-Surgical Pain Syndromes" Meeting; ERSA-Spain (2010)
- "Regional Anesthesia and Acute Pain" Annual Meeting; American Society of Anesthesiology (2010)
- "Thoracic Epidural Workshop, Paravertebral Workshop, Neuropathic Pain 101" Spring Meeting; American Society of Regional Anesthesia and Pain Medicine (2010)
- "Focus Session on Treatment Guidelines -- Treatment of Pain in the Elderly" PGA; New York State Society of Anesthesiologists (2009)
- "Parallel Session on Cancer Pain" Annual Fall Meeting; American Society of Regional Anesthesia and Pain Medicine (2009)
- "Sodium Channels: Their Role in Neuropathic Pain, Breakthrough Pain" Meeting; Spanish Society of Pain Medicine (2009)
- "Thoracic Epidural Anesthesia and Analgesia" Annual Spring Meeting; American Society of Regional Anesthesia and Pain (2009)
- "Ultrasound Is Not Superior To Other Imaging Modalities in Interventional Pain Procedures" Annual Meeting; American Society of Anesthesiology (2009)
- "Abstracts in Pain Management" Meeting; European Society of Regional Anesthesia (2008)
- "Cancer Pain Management" Annual Fall Meeting; American Society of Regional Anesthesia and Pain (2008)
- "Comprehensive Management of Neuropathic Pain in the Elderly" Meeting; American Association of Pain Management (2008)
- "Opioids in Non-Cancer Pain: The Debate Goes On" Annual Meeting; American Society of Anesthesiology (2008)
- "Sophistry in Regional Anesthesia and Pain, Epidural Steroids: The Nuts and Bolts" Annual Meeting; Guatemalan Society of Anesthesiology (2008)
- "Thoracic Epidural Anesthesia and Analgesia" Annual Meeting; American Society of Regional Anesthesia and Pain (2008)
- "Chronic and Cancer Pain - Clinical and Basic" Annual Meeting; American Society of Anesthesiology (2007)
- "Conventional versus Pulsed Radiofrequency: PRO" Annual Meeting; Cleveland Clinic Foundation (2007)
- "Implementing Intratheal Therapy: The Nuts and Bolts" Annual Meeting; American Association of Pain Management (2007)
- "Intrathecal Polyanalgesia: Pros and Cons" Annual Meeting; Cleveland Clinic Foundation (2007)
- "Thoracic Epidural Anesthesia" Annual Spring Meeting; American Society of Regional Anesthesia and Pain (2007)
- "Differences Between Opioid-Induced Tolerance and Hyperalgesia: Optimizing Treatment With Opioids and Adjuvant Therapy" Annual Meeting; American Society of Anesthesiology (2006)
- "Neurobiology of Neuropathic Pain" Annual Meeting; Spanish Rheumatology Association (2006)
- "Neurolysis of the Sympathetic Axis for Cancer Pain" World Congress; Regional Anesthesia and Pain (2006)
- "Treatment of Cancer Pain" Annual Meeting; American Society of Anesthesiology (2006)
- "Unusual Pain Syndromes" International Congress; 12th International Pain Clinica Congress; Pain Clinic (2006)
- "Visceral and Sympathetic Blocks" Annual Meeting; American Society of Anesthesiology (2006)
- "What is New in Epidural Opioid Therapy" Annual Meeting; Pain Society of Argentina (2006)
- "What's New in Spinal Anesthesia" Meeting; Regional ESRA (2006)
- "Conventional and Unconventional Pain Techniques" PGA Meeting; New York State Society of Anesthesiologists (2005)
- "Neurolytic Sympathetic Blocks" Annual Meeting; American Society of Anesthesiology (2005)
- "Neuromodulation for Cancer Related Pain" Bi-Annual Meeting; AOSRA (2005)
- "Safety Aspects of Postoperative Pain Management" World Congress; World Congress of Pain (2005)
- "Thoracic Epidural Anesthesia" Annual Meeting; American Society of Anesthesiology (2005)
Service Activities:
- ASA Ad Hoc Scientific Content Subcommittee on Pain Medicine; Committee Member (2005–2006)
- ASRAPM Scientific Program Committee 2005 Fall Meeting; Committee Member (2005)
- NCCN Pain Menegement Guidelines Committee; Committee Member (2004–present)
- ASRAPM Scientific Program American Society of Regional Anesthesia and Pain Management -- 2004 Fall Meeting; Chair (2003–2004)
- ASRA Education Committee; Committee Member (2003–present)