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Weiguo                         Liu

Weiguo Liu MD, PhD

Department of Pathology and Anatomical Sciences

Clinical Assistant Professor

Specialty/Research Focus

Surgical Pathology

Professional Summary:

I have broad interests in pathology with special interests in oncologic surgical pathology and gastrointestinal pathology.
After graduating from medical school and practicing general surgery for a couple of years, I enrolled in a Ph. D program at Roswell Park Cancer Institution in the department of molecular pharmacology and cancer therapeutics to fulfill my interest in finding tumor makers that can help to diagnose cancer earlier and to develop target therapy to improve cancer patients’ life quality. I finished my Ph. D program successfully with a couple of publications and a patent. Realizing that pathology is the best specialty that can help me to combine my research interests with clinical practice, I did four years’ pathology residency training at State University New York at Buffalo followed two years’ fellowship training at Memorial Sloan Kettering Cancer Center. These trainings not only helped me to develop excellent clinical skills but also provided me with good opportunities to perform translational research.
I regard that my career is composed of three major parts and it is in these three parts that I have set my career goals and been working hard to achieve them. The first is clinical service. As a well-trained and board certified pathologist on anatomic and clinical pathology, I practice general surgical pathology and some clinical pathology. I corporate with clinicians to provide high-quality clinical service to our patients for the management of their diseases. The second is research. I think research is the most important way to help us keep practicing up-to-date medicine. The fast developing advanced techniques provide us with many opportunities to improve our clinical practices. Currently, I continue working on a project I started during my fellowship which is using next generation sequencing to analyze genomic alternations in ampullary carcinoma. I am also interested in evaluating liver fibrosis by using quantitative image analysis tools. The university and department of pathology provide great research opportunities. The third is teaching. I have been actively involving in teaching medical students and residents during my residency and fellowship training and I really enjoy it. Now my teaching activities include core lectures, signing out cases with residents and giving unknown conferences.

Education and Training:
  • Fellowship, Oncologic surgical pathology and Gastrointestinal pathology, Memorial Sloan-Kettering Cancer Center (2013)
  • Residency, pathology, State University of New York at Buffalo (2011)
  • PhD, Roswell Park Cancer Institute (2005)
  • MD, Norman Bethune Medical University (2000)
  • MS, Norman Bethune Medical University (1997)
  • MB, Norman Bethune Medical University (1992)

Journal Articles:
  • Winter JM, Tang LH, Klemstra DS, Liu W, Linkov I, Brennan MF, D'Angelica MI, DeMatteo RP, Fong Y, Jarnagin WR, O'Reily EM, Allen PJ. Failure Patterns in Resected Pancreas Adenocarcinoma: Lack of Predicted Benefit to SMAD4 Expression. Ann Surg. 2013.
  • Liu W, Bennett M, Helm T. Canine Melanoma: A Comparison with Human Pigmented Epithelioid Melanocytoma. Int J Dermatol. 2011; 50(12).
  • Liu W, Iqbal J, Khoury T. Two Morphologically Similar but Biologically Different Diseases. Journal of Cutaneous Pathology. 2010; 37(11).
  • Al-Agha O, Liu W, Chandrasekhar R, Wilding G, Tan D, Alrawi S, Khoury T. CD138 (Syndecan-1) in thymic neoplasms: correlation with various World Health Organization types and clinical outcome. Int J Clin Exp Pathol. 2010; 3(3).
  • Paczos T, Liu W, Chen F. Human Papillomavirus Vaccine - Where are We Now?. NAJMS. 2010; 3(4).
  • Liu W, Nakhla H, Mojica M, Chen F. The Expression of TTF-1 in Small Cell Carcinoma of the Urinary Bladder. NAJMS. 2009; 2(3).
  • Liu W, Bloom DA, Cance WG, Kurenova EV, Golubovskaya VM, Hochwald SN. FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells. Carcinogenesis. 2008.
  • Chen Y, Ohkubo K, Zhang M, Wenbo E, Liu W, Pandey SK, Ciesielski M, Baumann H, Erin T, Fukuzumi S, Kadish KM, Fenstermaker R, Oseroff A, Pandey RK. Photophysical, electrochemical characteristics and cross-linking of STAT-3 protein by an efficient bifunctional agent for fluorescence image-guided photodynamic therapy. Photochemical Photobiological Science. 2007; 6(12).
  • Khoury T, Zakharia Y, Tan W, Kulkarni S, Liu W, Zhang S, Wilding GE, Edge S. Breast hormonal receptors test should be repeated on excisional biopsy after negative core needle biopsy.. Breast J. ; 17(2).

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Contact Information

Buffalo General Medical Center
Kaleida Health Services
High Street
Buffalo, NY 14203
Phone: 859-2140

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