Yun Wu PhD
Yun Wu
PhD
Professor of Biomedical Engineering
Department of Biomedical Engineering
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Biomedical Engineering; Nanoparticles; Nanotechnology
Professional Summary:
My research applies engineering pricinples and design concepts to develop novel therapeutics and diagnostics (theranostics) for the diagnosis and treatment of cancer and other deadly diseases.
Education and Training:
- PhD, Chemical and Biomolecular Engineering, The Ohio State University (2009)
Employment:
- Professor, Biomedical Engineering, University at Buffalo, The State University of New York (2023-present)
- Associate Professor, Biomedical Engineering, University at Buffalo, State University of New York (2019–2023)
- Assistant Professor, Biomedical Engineering, University at Buffalo, State University of New York (2013–2019)
- Postdoctoral Research Associate, Nanoscale Science and Engineering Center, The Ohio State University (2009–2013)
Research Expertise:
- Research Expertise: cancer nanotherapeutics, extracellular vesicles, biosensors, cancer liquid biopsy
UB 2020 Strategic Strengths:
- Health and Wellness Across the Lifespan
Grants and Sponsored Research:
- September 2022–August 2027
Lung cancer early detection and immunotherapy response prediction and monitoring with an Exo-PROS liquid biopsy assay
NCI
Role: Principal Investigator
$3,120,685 - April 2023–March 2027
Multifunctional Biodegradable Zwitterionic Polymer-Drug Conjugates for Multidrug
NIBIB
Role: Co-Investigator
$2,388,081 - July 2022–June 2024
Exosomal Thomsen-Friedenreich glycoantigen as a new biomarker for lung cancer screening and early detection
NCI
Role: Principal Investigator
$431,992 - August 2020–July 2023
An inflammation-induced fibrosis-on-chip system for the testing of anti-fibrosis drugs
NHLBI
Role: Co-Investigator
$920,000 - September 2021–June 2023
Zwitterionic dendrimer-modified PEG for protein conjugation
NIBIB
Role: Co-Principal Investigator
$433,902 - March 2019–February 2023
Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection
NCI
Role: Principal Investigator
$565,427 - September 2019–August 2022
Exosome Protein microRNA One Stop (Exo-PROS) biosensor: a new liquid biopsy for precision cancer immunotherpay
Cancer Research Institute
Role: Principal Investigator
$200,000 - September 2017–February 2022
PFI: BIC: WearNet: Smart Health Monitoring & Diagnosis System Based on Wearable Nano-biosensing Networks
NSF
Role: Co-Principal Investigator
$1,047,141 - October 2019–December 2021
Development of Tumor Targeted Nanoparticles to Combat EGFR TKI Resistance
American Lung Association
Role: Co-Principal Investigator
$200,000 - September 2015–August 2021
Noninvasive Detection of Circulating RNAs for Lung Cancer Early Detection and Prognosis
NCI
Role: Principal Investigator
$1,279,946 - September 2015–May 2021
Fibrotic Microtissue Chips for Screening of Anti-fibrotic Therapies
NIBIB
Role: Co-Investigator
$1,407,173 - September 2016–August 2020
Cationic Diblock Polymer-Drug Conjugate-Based Nanoparticles for Drug-Gene Co-Delivery
NSF
Role: Co-Principal Investigator
$420,000 - June 2017–May 2020
Synthetic Biodegradable Zwitterionic Polymers
NIBIB
Role: Co-Principal Investigator - July 2016–October 2019
Targeting the BRK-P27-CDK4 Axis in Cancer
NCI
Role: Co-Investigator
$1,147,641 - September 2014–August 2017
Physiologically Based Pharmacokinetic Model for Drugs Encapsulated into Liposomes
FDA
Role: Co-Investigator
$592,071