Chukwumere E. Nwogu MD, PhD, FACS

Chukwumere Nwogu

Chukwumere E. Nwogu


Department of Surgery

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus

Oncology; Thoracic Surgery

Contact Information
Roswell Park Cancer Institute
Carlton House
Elm & Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-5873
Fax: (716) 845-7692

Professional Summary:

Research Interests:
A. Lymphatic Spread of Lung and Esophageal Cancer
B. Minimally Invasive Esophageal and Lung Cancer
C. Robotic Surgery
D. Oncology in Resource Limited Environments

Education and Training:

  • PhD, Cancer Pathology and Prevention, University at Buffalo, N/A (2012)
  • Fellowship, Brigham & Women's Hospital (1999)
  • Residency, University of Massachusetts Medical Center, Worcester (1998)
  • Residency, Flushing Hospital – Albert Einstein College of Medicine, New York (1995)
  • Internship, Internal Medicine Intern, Harlem Hospital – Columbia University College of Physicians & Surgeons, New York (1990)
  • Internship, University of Nigeria Teaching Hospital, Enugu, Nigeria (1988)
  • BS, University of Nigeria, College of Medicine, Enugu, Nigeria (1987)


  • Professor of Surgery, Surgery, University at Buffalo (2009-present)
  • Professor of Oncology, Thoracic Surgery, Roswell Park Cancer Institute (2009-present)
  • Physician, Surgery, University at Buffalo (2000–2009)
  • Physician, Niagara Falls Memorial Medical Center (1999–2004)

Research Expertise:

  • Oncology and Benign Esophageal Diseases

Grants and Sponsored Research:

  • January 2008–January 2013
    Radio-guided Detection of Lymph Node Metastasis in Non-small Cell Lung Cancer
    National Cancer Institute/Thoracic Surgery Foundation for Research and Education
    Role: Principal Investigator
  • January 2009–January 2011
    Molecular Mechanisms of Lymph Node Metastasis in Non-small Cell Lung Cancer
    National Cancer Institute
    Role: Principal Investigator
  • January 2006–January 2010
    A Phase II Trial of Preoperative Irinotecan, Cisplatin and Radiation in Esophageal Cancer
    National Cancer Institute, Cancer and Leukemia Group B Protocol CALGB 80302
    Role: Co-Investigator
  • –January 2009
    Cancer Control in Resource Limited Environments
    International Union Against Cancer (UICC)
    Role: Principal Investigator
  • January 2004–December 2008
    Radioguided Detection of Lymph Node Metastases in Thoracic Malignancies
    Mae Stone Goode Trust (Local Philantropic Organization)
    Role: Principal Investigator
  • January 2004–January 2006
    Use of Proteomic Analysis of Serum Samples for Detection of Non-small Cell Lung Cancer
    National Cancer Institute, American College of Surgeons Oncology Group
    Role: Principal Investigator

Journal Articles:

  • Miller JA, Harris K, Roche C, Dhillon S, Battoo A, Demmy T, Nwogu CE, Dexter EU, Hennon M, Picone A, Attwood K, Yendamuri S. Sarcopenia is a predictor of outcomes after lobectomy. J Thorac Dis. 2018; 10(1).
  • Shafirstein G, Battoo A, Harris K, Baumann H, Gollnick SO, Lindenmann J, Nwogu CE. Photodynamic Therapy of Non-Small Cell Lung Cancer. Narrative Review and Future Directions. Ann Am Thorac Soc. 2016; 13(2).
  • Nurkin SJ, Nava HR, Yendamuri S, LeVea CM, Nwogu CE, Groman A, Wilding G, Bain AJ, Hochwald SN, Khushalani NI. Outcomes of endoscopic resection for high-grade dysplasia and esophageal cancer. Surg Endosc. 2014; 28(4).
  • Kukar M, Groman A, Malhotra U, Warren GW, Bogner P, Nwogu CE, Demmy TL, Yendamuri S. Small cell carcinoma of the esophagus: a SEER database analysis. Ann Surg Oncol. 2013; 20(13).
  • Yendamuri S, Huang M, Malhotra U, Warren GW, Bogner PN, Nwogu CE, Groman A, Demmy TL. Prognostic implications of signet ring cell histology in esophageal adenocarcinoma. Cancer. 2013; 119(17).
  • Nwogu CE, Yendamuri S, Tan W, Kannisto E, Bogner P, Morrison C, Cheney R, Dexter E, Picone A, Hennon M, Hutson A, Reid M, Adjei A, Demmy TL. Lung cancer lymph node micrometastasis detection using real-time polymerase chain reaction: correlation with vascular endothelial growth factor expression. J Thorac Cardiovasc Surg. 2013; 145(3).
  • May KS, Yang GY, Khushalani N, Chandrasekhar R, Wilding GE, Flaherty L, Malhotra HK, Russo RC, Warner JC, Yap JC, Iyer RV, Nwogu CE, Yendamuri S, Nava HR, Lamonica D, Thomas CR. MAG-3 Renal Scintigraphy With Change in Creatinine Clearance Following Chemoradiation to the Abdomen in Patients with Gastrointestinal Malignancies.. Journal of Gastrointestinal Oncology. 2010; 1(1).
  • Nwogu CE, Ezeome EE, Mahoney M, Okoye I, Michalek AM. Regional cancer control in south-eastern Nigeria: a proposal emanating from a UICC-sponsored workshop. West Afr J Med. 2010; 29(6).
  • May KS, Yang GY, Khushalani NI, Chandrasekhar R, Wilding GE, Flaherty L, Malhotra HK, Russo RC, Warner JC, Yap JC, Iyer RV, Nwogu CE, Yendamuri SS, Gibbs JF, Nava HR, Lamonica D, Thomas CR. Association of Technetium(99m) MAG-3 renal scintigraphy with change in creatinine clearance following chemoradiation to the abdomen in patients with gastrointestinal malignancies. J Gastrointest Oncol. 2010; 1(1).
  • Bhaskarla A, Tang PC, Mashtare T, Nwogu CE, Demmy TL, Adjei A, Reid ME, Yendamuri S. Analysis of Second Primary Lung Cancers in the SEER Database.. Journal of Surg Res. 2010; 158(2).
  • Nwogu CE, Yendamuri S, Demmy TL. Thoracoscopic Pneumonectomy for Lung Cancer Affect Survival?. Ann Thor Surg. 2010; 89.
  • Tang L, Zirpoli G, Jayaprakash V, Reid ME, McCann SE, Nwogu CE, Zhang Y, Ambrosone CB, Moysich KB. Cruciferous Vegetable Intake is Inversely Associated with Lung Cancer Risk Among Smokers: A Case-Control Study.. BMC Cancer. 2010; 10.
  • Javle MM, Yang G, Nwogu CE, Wilding GE, O'Malley L, Vinjamaram S, Schiff MD, LeVea C, Clark KR, Prey JD, Smith PF, Nava HR, Pendyala L. Capecitabine, Oxaliplatin and Radiotherapy: A Phase IB Neoadjuvant Study for Esophageal Cancer with Gene Expression Analysis.. Cancer Investigation. 2009; 27(2).
  • Demmy TL, Tomaszewski G, Dy GK, Yendamuri S, Nwogu CE, Pendyala L, Ramnath N, Adjei AA. Thoracoscopic Organ Suffusion for Regional Lung Chemotherapy (preliminary results).. Annals of Thoracic Surgery. 2009; 88(2).
  • Nwogu CE. Sentinel Node and PET Mapping in Lung Cancer.. Seminars in Thoracic and Cardiovascular Surgery. 2009; 21(4).
  • Yendamuri S, Nwogu CE, Demmy TL. Thoracoscopic lobectomy with chest wall resection after neoadjuvant therapy. Innovations (Phila). 2009; 4(1).
  • Yang GY, McCloskey SA, Khushalani NI, Yap JC, Nwogu CE, Yendamuri SS, Nava HF, Thomas CR. Principals of Modern Radiation Techniques for Esophageal and Gastroesophageal Cancer.. Gastrointestinal Cancer Research. 2008; 2(5).
  • Javle M, Pande A, Iyer R, Yang G, LeVea C, Wilding G, Black J, Nava H, Nwogu CE. Pilot Study of Gefitinib, Oxaliplatin and Radiotherapy for Esophageal Adenocarcinomas: Tiddue Effect Predicts Clinical Response.. American Journal of Clinical Oncology. 2008; 31(4).
  • Chadha MK, Levea CM, Mashtare T, Wilding G, Javle MM, Nwogu CE. Cytokeratin Staining to Detect Residual Disease in Patients Undergoing Neoadjuvant chemoradiation Followed by Esophagectomy for Locally Advanced Esophageal Cancer.. Internet Journal of Oncology. 2008; 5(2).
  • O'Connor BM, Kaur Chadha M, Pande A, Lombardo JC, Nwogu CE, Nava HR, Yang G, Javle MM. Concurrent Oxaliplatin, 5-Fluorouracil and Radiotherapy in the Treatment of Locally Advanced Esophageal Carcinoma.. The Cancer Journal. 2007; 13(2).
  • Gibbs J, Rajput A, Chadha KS, Douglas WG, Hill H, Nwogu CE, Nava HR, Sabel MS. The Changing Profile of Esophageal Cancer Presentation and its Implication for Diagnosis.. Journal of National Medical Association. 2007; 99(6).
  • Javle M, Ailawadhi S, Yang GY, Nwogu CE, Schiff MD, Nava HR. Palliation of malignant dysphagia in esophageal cancer: a literature-based review. J Support Oncol. 2006; 4(8).
  • Platis IE, Nwogu CE. Chylothorax. Thorac Surg Clin. 2006; 16(3).
  • Demmy TL, Nwogu CE, Sussman MS. Triangular retractor facilitates minimally invasive lobectomy. J Thorac Cardiovasc Surg. 2005; 129(6).
  • Nwogu CE, Hill HC, Tan DF, Demmy TL, Takita H, Anderson TM. Localized Fibrous Tumors of the Pleura.. Clinical Pulmonary Medicine.. 2005; 12(1).
  • Pauly JL, Allison EA, Hurley EL, Nwogu CE, Wallace PK, Paszkiewicz GM. Fluorescent Human Lung Macrophages Analyzed by Spectral Confocal Laser Scanning Microscopy and Multispectral Cytometry.. Microscopy Research and Technique. 2005; 67.
  • Nwogu CE, Tan DF, McLean M. Diagnostic Dilemma: Persistent Superior Mediastinal Mass Following Treatment of Hodgkin's Lymphoma.. Case Reports and Clinical Practice Review. 2005; 6.
  • Ramnath N, Sommers E, Robinson L, Nwogu CE, Sharma A, Cantor A, Bepler G. Phase II Study of Neoadjuvant Chemotherapy with Gemcitabine and Vinorelbine in Resectable Non-Small-Cell Lung Cancer.. Chest. 2005; 128(5).
  • Hill HC, Nwogu CE, Loewen G, Pelow J, Dougherty TJ, Anderson TM. Off-Label Management of Primary Metastatic Endobronchial Tumor with Photodynamic Therapy.. Clinical Pulmonary Medicine. 2004; 11(2).
  • Demmy TL, Plante A, Nwogu CE, Takita H, Anderson TM. Discharge Independence with Minimally Invasive Lobectomy.. American Journal of Surgery. 2004; 188.
  • Jiang M, Anderson T, Nwogu CE, Tan D. Pulmonary Malignant Granular Cell Tumor.. World Journal of Surgical Oncology. 2003; 1(22).
  • Anderson TM, Hess SD, Egilmez NK, Nwogu CE, Lenox JM, Bankert RB. Comparison of human lung cancer/SCID mouse tumor xenografts and cell culture growth with patient clinical outcomes. J Cancer Res Clin Oncol. 2003; 129(10).
  • Tan DF, Deeb G, Wang J, Li Q, Slocum HK, Winston J, Wiseman S, Beck A, Sait S, Anderson TM, Nwogu CE, Ramnath N, Loewen G. HER-2/Neu Protein Expression and Gene Alteration in Stage 1-111a Non-Small Cell Lung Cancer: A Study of 140 Cases Utilizing a Combination of High Throughput Tissue Microarray, Immunohistochemistry and Fluorescent In-Situ Hybridization.. Diagnostic Molecular Pathology. 2003; 12(4).
  • Nwogu CE, Kanter PM, Anderson TM. Pulmonary Lymphatic Mapping in Dogs - Use of Technetium Sulfur Colloid and Isosulfan Blue for Pulmonary Sentinel Lymph Node Mapping in Dogs.. Cancer Investigation. 2002; 20(8).
  • Nwogu CE, Kanter PM, Anderson TM. Pulmonary lymphatic mapping in dogs: use of technetium sulfur colloid and isosulfan blue for pulmonary sentinel lymph node mapping in dogs. Cancer Invest. 2002; 20(7-8).
  • Anderson TM, Ray CW, Nwogu CE, Bottiggi AJ, Lenox JM, Driscoll DL, Urschel JD. Pericardial Catheter Sclerosis Versus Surgical Procedures for Pericardial Effusions in Cancer Patients.. Journal of Cardiovascular Surgery. 2001; 42.
  • Anderson TM, McMahon JJ, Nwogu CE, Pombo MW, Urschel JD, Driscoll DL, Lele SB. Pulmonary Resection in Metastatic Uterine and Cervical Malignancies.. Gynecologic Oncology. 2001; 86.
  • Davidson RS, Nwogu CE, Brentjens MJ, Anderson TM. The Surgical Management of Pulmonary Metastasis: Current Concepts.. Surgical Oncology. 2001; 10(1-2).
  • Anderson TM, Nwogu CE, Loree TR, Cheng CC, Hughes JM, Nava HR. Iatrogenic Esophagobronchial Fistula Arising in Irradiated Barrett's Esophagus.. International Journal of Gastrointestinal Cancer. 2001; 30(3).
  • Nwogu CE, Conlan AA. Acute Submucosal Esophageal Hemorrhage.. Annals of Thoracic Surgery. 1997; 68.
  • Golub R, Nwogu CE, Cantu R, Stein HD. Gallstone Shrapnel Contamination During Laparoscopic Cholicystectomy.. Surgical Endoscopy. 1994; 8(8).
  • Demmy TL, Platis I, Nwogu CE. Thoracoscopic Extrapleural Pneumonectomy for Mesothelioma.. Ann Thor Surg..
  • Kachare S, Dexter E, Nwogu CE, Demmy TL, Yendamuri S. Peri-operative Outcomes of Thoracoscopic Anatomic Resections in Patients with Limited Pulmonary Reserve.. JTCVS..
See all (33 more)

Books and Book Chapters:

  • Yendamuri S, Nwogu CE, Demmy TL. Malignant Pleural and Pericardial Effusions.. 2008.
  • Platis IE, Nwogu CE. Complications After Pulmonary Surgery: Chylothorax,. 2006.
  • Demmy TL, Nwogu CE. Malignant Pleural and Pericardial Effusions.. 2003.
  • Nwogu CE. Primary Malignant Neoplasms of the Lung.. 2001.
  • Platis IE, Nwogu CE. Benign Lung Masses..

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Contact Information

Roswell Park Cancer Institute
Carlton House
Elm & Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-5873
Fax: (716) 845-7692