Clare J. Twist MD, MS

Clare Twist

Clare J. Twist
MD, MS

Clinical Professor

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Pediatric Hematology-Oncology; Pediatrics

Contact Information
Roswell Park Cancer Institute
Department of Pediatrics
Elm and Carlton Streets
Buffalo, New York 14263
Phone: (716) 845-2333
Fax: (716) 845-8003
ctwist@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD


Education and Training:

  • Fellowship, Pediatric Hematology/Oncology, Harvard Medical School (1993)
  • Fellowship, Pediatric Hematology/Oncology, Harvard Medical School (1991)
  • Residency, Pediatrics, Northwestern University (1990)
  • Internship, Pediatrics, Northwestern University (1988)
  • MD, Medicine, Albany Medical College (1987)
  • MS, Natural Sciences/Immunology, University at Buffalo/Roswell Park Memorial Institute (1984)
  • BS, University of Notre Dame (1982)

Employment:

  • Fellowship Program Director, Hematology/Oncology, University at Buffalo (2018-present)
  • Attending Physician, Hematology/Oncology, Oishei Children‘s Hospital (2016-present)
  • Attending Physician, Hematology/Oncology, Roswell Park Comprehensive Cancer Center (2016-present)
  • Clinical Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2016-present)
  • Director, Pediatric Experimental Therapeutics, Roswell Park Comprehensive Cancer Center (2016-present)
  • Professor, Oncology, Roswell Park Comprehensive Cancer Center (2016-present)
  • Associate Professor, Pediatrics, Stanford University School of Medicine (2008–2016)
  • Attending Physician, Lucile Packard Children‘s Hospital (1999–2016)
  • Medical Director, Pediatric Oncology Unit, El Camino Hospital (2012–2014)
  • Assistant Professor, Pediatrics, Stanford University School of Medicine (2000–2008)
  • Acting Assistant Professor, Pediatrics, Stanford University School of Medicine (1999–2000)
  • Associate Physician, Hematology/Oncology, Brigham and Women‘s Hospital (1994–1999)
  • Attending Physician, Bone Marrow Transplant Service, Brigham and Women's Hospital (1994–1999)
  • Assistant in Medicine, Boston Children's Hospital (1993–1999)
  • Attending Physician, Bone Marrow Transplant Service, Boston Children's Hospital (1993–1999)
  • Instructor, Pediatrics, Harvard Medical School (1993–1999)
  • Attending Physician, Boston Children‘s Hospital (1990–1999)
  • Staff Physician, Dana-Farber Cancer Institute (1990–1999)
See all (8 more)

Awards and Honors:

  • Children's Memorial Hospital: Outstanding Resident Teaching Award (1990)
  • Albany Medical College: Lamb Foundation Prize (1987)
  • Albany Medical College: Senior Medical Student Special Award (1987)
  • Buffalo Spree Magazine: Top Doctors in Western New York (2019-2021)

Research Expertise:

  • Early Phase Clinical Trials in Children
  • Neuroblastoma

Journal Articles:

See all (27 more)

Books and Book Chapters:

  • Twist CJ, Tedder TF. (1995) In: "Structure of the Mouse HB15 Gene". Oxford University Press, 697-699.
  • Pauly JL, Twist CJ, Ovak G, Russell C, Constantino J. (1983) In: "Thymic Hormones and Lymphokines ‘83". Plenum Publishing Corporation

Abstracts:

  • Twist CJ, Kjelson L, McKenney A, Bonham CA, Esquivel C, Castillo RO. (2009) Treatment of Recurrent Post-Transplant Lymphoproliferative Disorder (PTLD) of the Central Nervous System (CNS) with High-Dose Methotrexate (HD-MTX). (Sep)

Professional Memberships:

  • American Society of Pediatric Hematology/Oncology (2006–present)
  • American Society of Clinical Oncology (2002–present)
  • American Academy of Pediatrics (2001–2005)
  • American Society of Hematology (2001–present)
  • Children's Oncology Group (2001–present)
  • American Society for Blood and Marrow Transplantation (1995–1999)
  • Massachusetts Medical Society (1994–1996)
  • American Medical Student Association (1983–1987)

Presentations:

  • "Prospective Analysis of EBV+ PTLD in a Multi-Center Study of Pediatric Transplant Recipients" American Transplant Congress; American Society of Transplant Surgeons/American Society of Transplantation (2018)
  • "Anti-Cancer Therapies" Pediatric Grand Rounds; University at Buffalo (2018)
  • "Premature Physeal Closure After Prolonged Fenretinide Exposure" Annual Meeting; Advances in Neuroblastoma Research Association (2016)
  • "Validation of Image-Defined Risk Factor (IDRF) Assignment in Patients with Intermediate-Risk Neuroblastoma: A Report from the Children’s Oncology Group Study ANBL0531" Annual Meeting; Advances in Neuroblastoma Research Association (2016)
  • "Premature Physeal Closure After Prolonged Fenretinide Exposure" Annual Meeting; American Society of Pediatric Hematology/Oncology (2016)
  • "Cancer Recurrence and Mortality After Pediatric Heart Transplantation for Anthracycline Cardiomyopathy" Annual Meeting; International Society for Heart and Lung Transplantation (2016)
  • "Neuroblastoma: Therapeutic Successes and Future Challenges" Bass Center Grand Rounds; Stanford University School of Medicine (2016)
  • "Measuring Pediatric Hematology/Oncology Fellows' Skills in Humanism and Professionalism: A Novel Assessment Instrument" Annual Meeting; American Society of Pediatric Hematology/Oncology (2015)
  • "Trends in End-of-Life Care in Pediatric Hematology, Oncology, and Stem Cell Transplant Patients" Annual Meeting; American Society of Pediatric Hematology/Oncology (2015)
  • "Neuroblastoma" Pediatric Hematology/Oncology Fellowship Core Lecture Series; Stanford University School of Medicine (2015)
  • "Maintaining Outstanding Outcomes Using Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma: A Report from the Children‘s Oncology Group Study ANBL0531" Annual Meeting; American Society of Clinical Oncology (2014)
  • "Maintaining Outstanding Outcomes Using Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma: A Report from the Children's Oncology Group Study ANBL0531" Annual Meeting; Advances in Neuroblastoma Research Association (2014)
  • "Post-Transplant Lymphoproliferative Disorders" Pediatric Solid Organ Transplant Symposium; Lucile Packard Children's Hospital (2014)
  • "Pediatric Oncology Highlights of the Day" Annual Meeting; American Society of Clinical Oncology (2013)
  • "Maintenance of Certification Learning Session: Neuroblastoma" Annual Meeting; American Society of Pediatric Hematology/Oncology (2013)
  • "Morbidity and Mortality Risks in Infants with Stage 4S Neuroblastoma: A Report from the Children’s Oncology Group Study ANBL0531, 'Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma'" Annual Meeting; Advances in Neuroblastoma Research Association (2012)
  • "Outcome Analysis of Non-High-Risk Neuroblastoma Patients Enrolled on Children’s Oncology Group Trials P9641 and A3961" Annual Meeting; Advances in Neuroblastoma Research Association (2012)
  • "Outcome Analysis of Non-High-Risk Neuroblastoma Patients Enrolled on Children’s Oncology Group Trials P9641 and A3961" Annual Meeting; American Society of Clinical Oncology (2012)
  • "Pediatric Oncology Highlights of the Day" Annual Meeting; American Society of Clinical Oncology (2012)
  • "Neuroblastoma" Radiation Oncology Residency Core Curriculum Lecture; Stanford University School of Medicine (2012)
  • "Post-Transplant Lymphoproliferative Disorders" Pediatric Nephrology Continuing Medical Education Lecture; Lucile Packard Children's Hospital (2012)
  • "Post-Transplant Lymphoproliferative Disorder: Is There a Role for 18F FDG PET/CT?" Annual Meeting; Radiological Society of North America (2011)
  • "Treatment of Recurrent Post-Transplant Lymphoproliferative Disorder (PTLD) of the Central Nervous System (CNS) with High-Dose Methotrexate (HD-MTX)" XI International Small Bowel Transplant Symposium; Intestinal Rehabilitation and Transplant Association (2009)
  • "Neuroblastoma" Radiation Oncology Residency Core Curriculum Lecture; Stanford University School of Medicine (2009)
  • "Pediatric Hematology: Oncology as a Career Choice" Pediatric Lecture Series; Stanford University School of Medicine (2009)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture; Lucile Packard Children's Hospital (2009)
  • "Isolated Tumor Cells are Routinely Detected by Immunohistochemistry in Histologically Negative Bone Marrow Biopsies from Neuroblastoma Patients" Annual Meeting; Advances in Neuroblastoma Research Association (2008)
  • "Nuclear Medicine Imaging in Pediatric Malignancies" Nuclear Medicine Grand Rounds; Stanford University School of Medicine (2008)
  • "Oncologic Emergencies" Stanford/Kaiser Emergency Medicine Core Curriculum Lecture; Stanford University School of Medicine (2008)
  • "Pediatric Hematology: Oncology as a Career Choice" Pediatric Lecture Series; Stanford University School of Medicine (2008)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture; Lucile Packard Children's Hospital (2008)
  • "A Phase I Study of a Novel Human Monoclonal Antibody (mAb216) with Chemotherapy for the Treatment of Patients with Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemia" Annual Meeting; American Society of Hematology (2007)
  • "Retrospective Survey of Children Treated for Relapsed Acute Lymphoblastic Leukemia (Complete Remission (CR) Rates): A Report from the Therapeutic Advances in Childhood Leukemia (TACL) Consortium" Annual Meeting; American Society of Hematology (2007)
  • "Intermediate-Risk Neuroblastoma" Parent Conference; Children's Neuroblastoma Cancer Foundation (2007)
  • "Neuroblastoma Update" Pediatric Oncology Grand Rounds; University of Texas Southwestern (2007)
  • "Pediatric Hematology/Oncology as a Career Choice" Pediatric Lecture Series; Stanford University School of Medicine (2007)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture; Lucile Packard Children's Hospital (2007)
  • "Perinatal Neuroblastoma" Neonatology Lecture Series; Lucile Packard Children's Hospital (2007)
  • "Post-Transplant Lymphoproliferative Disorders" Radiation Oncology Residency Core Curriculum Lecture; Stanford University School of Medicine (2007)
  • "Treatment of Neuroblastoma: A Paradigm for Multidisciplinary Care" Leadership Forum; Lucile Packard Children's Hospital (2007)
  • "Mature Results of a Prospective Trial of Rituximab in Patients (pt) with Post-Transplant Lymphoproliferative Disorder (PTLD) Unresponsive or Ineligible for Reduced Immunosuppression (RIS)" Annual Meeting; American Society of Hematology (2006)
  • "A Phase I Clinical Trial of the Hu14.18-IL2 (EMD 273063) as a Treatment for Children with Refractory or Recurrent Neuroblastoma and Melanoma: A Study of the Children’s Oncology Group" Annual Meeting; Advances in Neuroblastoma Research Association (2006)
  • "Oncologic Emergencies" Stanford/Kaiser Emergency Medicine Core Curriculum Lecture; Stanford University School of Medicine (2006)
  • "Pediatric Hematology/Oncology as a Career Choice" Pediatric Lecture Series; Stanford University School of Medicine (2006)
  • "Pediatric Oncologic Emergencies" Continuing Medical Education Lecture Series; Watsonville Community Hospital Emergency Department (2006)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture; Lucile Packard Children's Hospital (2006)
  • "Neuroblastoma in a Patient with Noonan Syndrom: Possible Genotype/Phenotype Correlations in PTPN11" Annual Meeting; American Society of Human Genetics (2005)
  • "Impact of Body Composition on Pharmacokinetics of Doxorubicin in Pediatric Patients: A Glaser Pediatric Research Network Study" Annual Meeting; American Society of Clinical Oncology (2005)
  • "Low Stage Neuroblastoma" Parent Conference; Children's Neuroblastoma Cancer Foundation (2005)
  • "Pediatric Liver Tumors" Pediatric Liver Transplant Conference; Lucile Packard Children's Hospital (2005)
  • "Pediatric Oncology Cases" Pediatric Residency Core Lecture; Lucile Packard Children's Hospital (2005)
  • "Wilms Tumor" Radiation Oncology Residency Core Curriculum Lecture; Stanford University School of Medicine (2005)
  • "Age Continues to be a Powerful Predictor of EFS and OS in Neuroblastoma" Annual Meeting; Advances in Neuroblastoma Research Association (2004)
  • "Neuroblastoma" Radiation Oncology Residency Core Curriculum Lecture; Stanford University School of Medicine (2004)
  • "Update on Neuroblastoma" Nuclear Medicine Grand Rounds; Stanford University School of Medicine (2004)
  • "Monoclonal Antibody 216 (MAb 216), a VH4-34 Encoded Antibody, is a Novel Cytotoxic Agent for B-Progenitor Acute Lymphoblastic Leukemia (ALL)" Annual Meeting; American Society of Hematology (2003)
  • "Interactive Encoding of Whole Body 123I-MIBG Images in the Evaluation of Patients with Neuroblastoma" 4th European Symposium on Paediatric Nuclear Medicine; European Association of Nuclear Medicine (2003)
  • "Oncologic Emergencies" Stanford/Kaiser Emergency Medicine Core Curriculum Lecture; Stanford University School of Medicine (2003)
  • "Update on Neuroblastoma" Nuclear Medicine Grand Rounds; Stanford University School of Medicine (2003)
  • "Post-Transplant Lymphoproliferative Disorders" Pediatric Infectious Disease Conference; Lucile Packard Children's Hospital (2002)
  • "Rituximab is Effective Therapy for Post-Transplant Lymphoproliferative Disorder (PTLD) Not Responding to Reduction in Immunosuppression: A Prospective Trial in Adults and Children" Annual Meeting; American Society of Clinical Oncology (2001)
  • "Neuroblastoma 2001" Pediatric Grand Rounds; Lucile Packard Children‘s Hospital (2001)
  • "New Treatments for Genetic Diseases" Annual Meeting; New England Regional Genetics Group (1998)
  • "Cytoxan and Total Body Irradiation Conditioning Results in Stable Donor Marrow Engraftment in Patients with Metabolic Storage Diseases Undergoing Allogeneic Bone Marrow Transplantation" Annual Meeting; American Society of Pediatric Hematology/Oncology (1997)
  • "Bone Marrow Transplantation for Metabolic Storage Diseases" Pediatric Oncology Grand Rounds; Dana-Farber Cancer Institute (1997)
  • "Bone Marrow Transplantation for Metabolic Storage Diseases" Bone Marrow Transplantation Conference; Harvard Medical School (1997)
  • "The Use of Defibrotide (DF) in BMT-Associated Veno-Occlusive Disease (VOD)" Annual Meeting; American Society of Clinical Oncology (1996)
  • "Structure of the Mouse CD83 Gene" Annual Meeting; American Society of Hematology (1995)
  • "Structure of the Mouse HB15 Gene" 5th International Workshop on Human Leukocyte Differentiation Antigens; Human Cell Differentiation Molecules (1993)
See all (59 more)

Service Activities:

  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology Deputy Medical Editor (2017–present)
  • Cincinnati Children's Hospital: Data Safety and Monitoring Committee; Committee Member (2016–present)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology Past Chair (2014–2015)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellow Trainee Clinical Mentor (2013–2016)
  • Lucile Packard Children's Hospital: Interns/Residents; Advisor (2013–2016)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Clinical Competency Committee; Chair (2013–2016)
  • Stanford University Cancer Center: Scientific Review Committee; Committee Member (2013–2016)
  • American Society of Pediatric Hematology/Oncology: Certification and Continuing Education Committee; Committee Member (2013–2015)
  • American Society of Clinical Oncology: Clinical Cancer Advances Journal Editorial Advisor (2013–present)
  • National Cancer Institute: PDQ Pediatric Treatment Editorial Advisory Board; Board Member (2013–present)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellowship Scholarly Oversight Committee; Committee Member (2012–2016)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellowship Recruitment Committee; Committee Member (2012–2016)
  • Lucile Packard Children's Hospital: Medical Executive Committee; Committee Member (2012–2015)
  • American Society of Pediatric Hematology/Oncology: Training Committee; Committee Member (2012–2015)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology; Chair (2012–2014)
  • National Heart, Lung, and Blood Institute: Taskforce on the Future of the Workforce in Hematology; Member (2012–2014)
  • American Society of Clinical Oncology 2013 Annual Meeting: Pediatric Oncology Scientific Program Committee Track Leader (2012–2013)
  • American Society of Clinical Oncology 2013 Annual Meeting: Pediatric Oncology Education Program Committee; Committee Member (2012–2013)
  • Advances in Neuroblastoma Research Annual Meeting: Scientific Program Committee; Committee Member (2012)
  • Lucile Packard Children's Hospital: Tissue Committee; Committee Member (2011–2016)
  • American Society of Clinical Oncology 2012-2014 Annual Meetings: Pediatric Oncology Scientific Program Committee; Committee Member (2011–2014)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology Credentials Committee; Committee Member (2010–2014)
  • New Approaches to Neuroblastoma Therapy Consortium: Scientific Review Committee; Committee Member (2010–2012)
  • Lucile Packard Children's Hospital: Pediatric Oncology Chemotherapy Error Prevention Committee; Committee Member (2010–2012)
  • Lucile Packard Children's Hospital: Bass Center Process Improvement Committee; Committee Member (2010–2012)
  • Dana-Farber Cancer Institute: Claudia Adams Barr Program in Innovative Basic Cancer Research Presidential Scientific Advisory Council; Member (2010–present)
  • American Board of Pediatrics: Subspecialties Committee; Committee Member (2009–2014)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program Faculty Mentor (2008–2016)
  • American Board of Pediatrics: Subboard of Pediatric Hematology/Oncology; Board Member (2008–2013)
  • Pediatric Transplantation Journal; Ad Hoc Reviewer (2008–present)
  • Stanford University: Med Scholars Program Faculty Mentor (2007–2009)
  • Stanford University School of Medicine: Pediatric Journal Club Faculty Facilitator (2007–2008)
  • Stanford University: Pediatric Hematology/Oncology Fellowship Program - Fellowship Boot Camp Lecture Series Lecturer (2006–2012)
  • Stanford University School of Medicine: Pediatric Lecture Series Lecturer (2006–2010)
  • Pediatric Blood and Cancer Journal; Ad Hoc Reviewer (2006–present)
  • Children's Oncology Group: Neuroblastoma Steering Committee; Committee Member (2006–present)
  • Stanford University: Pediatric Residency Program - Core Lecture Series Lecturer (2005–2010)
  • Stanford University: Pediatric Oncology Bereavement Program Faculty Supervisor (2003–2016)
  • Lucile Packard Children's Hospital: Pediatric Hematology/Oncology Bereavement Committee; Committee Member (2003–2016)
  • Stanford University: Pediatric Residency Program - Hematology/Oncology Ambulatory Selective Rotation; Director (2003–2015)
  • Stanford University: Pediatric Residency Program - Hematology/Oncology Inpatient Rotation; Director (2003–2012)
  • New Approaches to Neuroblastoma Therapy Consortium: Study Committee NANT 2001-2003: A Phase I Study of CEP-701 in Patients with Refractory Neuroblastoma; Committee Member (2003–2010)
  • New Approaches to Neuroblastoma Therapy Consortium: Data Safety and Monitoring Committee; Committee Member (2003–present)
  • Lucile Packard Children‘s Hospital: Division of Hematology/Oncology Peer Review Committee; Chair (2002–2015)
  • Children's Oncology Group: Intermediate Risk Neuroblastoma Study (ANBL0531); Chair (2002–2013)
  • Stanford University School of Medicine: Medical Student Sub-Internship in Pediatric Hematology/Oncology; Director (2002–2012)
  • Lucile Packard Children's Hospital: Care Improvement Committee; Committee Member (2001–2016)
  • American Academy of Pediatrics: PREP; Editorial Board Member (2001–2003)
  • New Approaches to Neuroblastoma Therapy Consortium: Neuroblastoma Disease Committee; Committee Member (2001–present)
  • Stanford University: Pediatric Oncology Tumor Board Faculty Supervisor (2000–2016)
  • Lucile Packard Children's Hospital: Quality Improvement Committee; Committee Member (2000–2015)
  • Lucile Packard Children's Hospital: Division of Pediatric Hematology/Oncology Quality Assurance Liaison (2000–2014)
  • Lucile Packard Children's Hospital: Critical Care Committee; Committee Member (2000–2009)
  • Stanford University School of Medicine: Medical Student Clerkship in Pediatric Hematology/Oncology; Director (2000–2005)
  • Lucile Packard Children's Hospital: Pediatric Oncology Medication Error Committee; Committee Member (2000–2002)
  • Pediatric Bone and Marrow Transplant Consortium: Immunologic and Metabolic Disorders Strategy Group; Member (2000–2002)
  • Lucile Packard Children's Hospital: Sedation Committee; Committee Member (2000–2001)
  • Journal of Clinical Oncology; Ad Hoc Reviewer (2000–present)
  • Journal of Pediatric Hematology/Oncology; Ad Hoc Reviewer (2000–present)
  • Dana-Farber Cancer Institute: Marathon Challenge Governing Board; Board Member (1998–present)
  • Dana-Farber Cancer Institute: Committee on Sexual Harassment In-House Sexual Harassment Trainer (1997–1999)
  • Dana-Farber Cancer Institute: Human Protection Committee; Committee Member (1996–1999)
  • Dana-Farber Cancer Institute: Pediatric Oncology Operations Committee; Committee Member (1996–1999)
  • Boston Children‘s Hospital: Oncology/Bone Marrow Transplant Resident Education Committee; Committee Member (1994–1999)
  • Dana-Farber Cancer Institute: Pediatric Oncology Clinic Clinic Leader (1994–1998)
  • Dana-Farber Cancer Institute: Marathon Challenge Patient Partner Program Committee; Committee Member (1994–present)
  • Harvard Medical School: Patient-Doctor II Course in Physical Diagnosis Tutor (1993–1996)
  • Dana-Farber Cancer Institute: Pediatric Oncology Protocol Conference; Coordinator (1993–1994)
  • Dana-Farber Cancer Institute: Marathon Challenge for Claudia Adams Barr Program in Innovative Basic Cancer Research; Participant (1993–present)
  • Albany Medical College: Admissions Committee; Committee Member (1985–1987)
  • Children's Oncology Group: Roswell Park Comprehensive Cancer Center Site Principal Investigator

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Contact Information

Roswell Park Cancer Institute
Department of Pediatrics
Elm and Carlton Streets
Buffalo, New York 14263
Phone: (716) 845-2333
Fax: (716) 845-8003
ctwist@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD