Manoj J. Mammen MD

Manoj Mammen

Manoj J. Mammen
MD

Associate Professor

Department of Medicine

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Critical Care Medicine; Internal Medicine; Pulmonary; Pulmonary & Critical Care Medicine; Pulmonary Disease

Contact Information
Buffalo General Medical Center
100 High Street, B-8
Buffalo, New York 14203
Phone: (716) 859-2271
Fax: 7168591491
mammen@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD


Professional Summary:

I am engaged in clinical, teaching and research responsibilities related to the evaluation and treatment of patients with pulmonary disease or patients who are critically ill. My inpatient practice situated at the medical intensive care unit at the Buffalo General Medical Center positions me to provide ongoing medical care to patients who are critically ill and require significant life support therapies to sustain life or vital bodily functioning. I am specifically interested in ARDS, asthma, chronic obstructive pulmonary disease, interstitial lung disease, pleural disease, pulmonary hypertension and lung cancer, but deal with a variety of lung disease.

I also evaluate patients with pulmonary disorders at the UBMD practice location at Conventus. As a member of the UBMD pulmonary division, I provide inpatient pulmonary consultation at both BGMC and Roswell Park Cancer Institute.

I am actively involved in teaching medical students, residents, and fellows about the appropriate care of the patient with either pulmonary disease and critical illness.

Education and Training:

  • MS, Genetics, Genomics and Bioinformatics, State University of New York at Buffalo (2016)
  • Fellowship, Pulmonary & Critical Care Medicine, Baylor College of Medicine (2010)
  • Residency, Internal Medicine, Baylor College of Medicine (2007)
  • MD, Medicine, Rutgers New Jersey Medical School (2004)
  • BA, Molecular Biology & Biochemistry/Computer Science, Rutgers University (1999)

Employment:

  • Associate Professor, Medicine, State University of New York at Buffalo Jacobs School of Medicine & Biomedical Sciences (2020-present)
  • Section Chief of UB Pulmonary at Buffalo General Medical Center, Medicine, State University of New York at Buffalo Jacobs School of Medicine & Biomedical Sciences (2020-present)
  • Adjunct Assistant Professor, Biomedical Informatics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2014-present)
  • Assistant Professor, Medicine, State University of New York at Buffalo Jacobs School of Medicine & Biomedical Sciences (2010–2020)
  • Medical Director, Western New York Lung Cancer Screening Program, Kaleida Health (2013–2016)
  • Student Family Healthcare Center (SFHCC) director, Rutgers New Jersey Medical School (2002–2004)
  • Computer Consultant, NCS technologies (1999–2000)

Awards and Honors:

  • Empire Clinical Research Investigator Program Fellow in Center for Nanomedicine (2014)
  • Gold Humanism Honor Society (2004)
  • Thesis with Honors, Rutgers University (1999)
  • Robert C. Byrd Federal Scholarship (1995)
  • Rutgers Presidential Scholarship (1995)

Research Expertise:

  • Biomedical Informatics
  • COVID19: Co-author of two clinical practice guidelines, ICU and pulmonary clinician who treats patients with COVID19 and teaches medical students, residents, and fellows on COVID19 management.
  • Critical Care Medicine
  • Data Science
  • Microbiome
  • Pulmonary medicine

Research Centers:

  • Center of Excellence in Bioinformatics and Life Sciences
  • Clinical and Translational Research Center (CTRC)

UB 2020 Strategic Strengths:

  • Extreme Events: Mitigation and Response
  • Health and Wellness Across the Lifespan
  • Information and Computing Technology
  • Integrated Nanostructured Systems
  • Molecular Recognition in Biological Systems and Bioinformatics

Grants and Sponsored Research:

  • October 2020–August 2022
    The Network Biology of Pathogen-Host Interactions Driving Exacerbation in Chronic Obstructive Pulmonary Disease (COPD)
    Department of Defense, U.S. Army Medical Research and Materiel Command, Congressionally Directed Medical Research Programs
    Role: Co-Investigator
    $1,057,527
  • July 2018–June 2019
    UB CAT: Circuit Clinical Data Collection and Analytics Systems, phase II
    UB CAT
    Role: Principal Investigator
    $197,563
  • July 2016–June 2019
    UB Genome, Environment, and Microbiome Community of Excellence (GEM) pilot study grant:The Airway Microbiome and Lung cancer in a COPD cohort
    University at Buffalo
    Role: Principal Investigator
    $20,000
  • May 2018–April 2019
    CTSI Pilot Study: Linking New York State Databases to Identify Risk Factors and Gaps in care for rural and urban health disparities in lung cancer
    CTSI
    Role: Co-Investigator
    $50,000
  • November 2017–October 2018
    UB CAT: Circuit Clinical Data Collection and Analytics Systems
    UB CAT
    Role: Principal Investigator
    $486,184
  • October 2016–October 2017
    AstraZeneca AB, D6571C00001
    Role: Co-Investigator
    $8,000
  • July 2016–July 2017
    Epigenetics profiling of Exacerbation Susceptibility in Chronic Obstructive Pulmonary Disease
    CTSA UB UR Collaborative Genomics Pilot Program Award
    Role: Co-Investigator
    $75,000
  • January 2014–December 2016
    Empire Clinical Research Investigator Program: Center for Nanomedicine Fellow
    Role: Co-Investigator
    $292,000
  • April 2014–June 2016
    A Phase I Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Safety, Tolerability, and Pharmokinetics of GS-5745 in Subjects
    Gilead
    Role: Co-Principal Investigator
    $22,260

Journal Articles:

See all (25 more)

Books and Book Chapters:

  • Mahajan SD, You Y, Aalinkeel R, Reynolds JL, Nair, Bindukumar B, Mammen MJ, Ignatowski TA, Cheng, Chong, Schwartz SA. (2016) Biodegradable Nanoparticle-Based Antiretroviral Therapy across the Blood-Brain Barrier.
  • Hirshkowitz, M, Mammen M,. (2010) Emergent sleep events related to medical treatment. Oxford University Press.
  • Mahajan SD, Aalinkeel R, Reynolds JL, Nair BB, Mammen MJ, Dai L, Prasad PN, Schwartz SA. (2015) Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases. Elsevier.

Abstracts:

  • Mammen MJ, Waldron N, Valiyaparambil S, Wrona C, Sethi S. (2018) Distinct Airway Microbiome Patterns Associated with Frequent Exacerbator Phenotype in COPD. (May)
  • Mammen MJ, Buck M, Sun Y, Waldron N, Valiyaparambil S, Wrona C, Sethi S. (2018) Distinct Airway Microbiome Patterns Associated with Lung Cancer Development in a COPD Cohort. (May)
  • Hesselbacher, S., Xu, C., Tsai, C.L., Schabath, M., Mammen MJ, Perusich, S., Coxson, H.O., Krowchuk, N.M., Corry, D., Kheradmand, F. (2011) Clinical And Immunologic Phenotypes Dictate Physiologic Outcome In COPD: Results From The LES-COPD Study. (May) A1016
  • Mammen MJ, Qu J, Sethi S. (2012) Comprehensive Proteomic Profiling Of Bronchoalveolar Lavage Fluid Of Individuals With COPD Compared To Healthy Controls. (May) A3747
  • Castner J, Jungquist C, Mammen MJ, Pender J J, Licata O, Wilding G, Sethi S. (2018) Developing Multivariable Prediction Models of Asthma Control Components Using Fitness Tracker Sleep Patterns in Women. (May)
  • Mammen MJ, Tsompana M, Buck M, Biswal S, Criner GJ, Sethi S. (2017) Effect Of Sulforaphane Treatment On The Airway Microbiome In COPD. (May)
  • Parikh NU, Mahajan SD, Aalinkeel R, Reynolds JL, Nair BN, Sykes DE, Mammen MJ, Schwartz SA. (2015) Galectin-1 is Neuroprotectice and Reverses Methamphetamine Induced Blood Brain Barrier Breakdown. (May)
  • Aalinkeel R, Abou-Jaoude E, Parikh, N, Reynolds JL, Sykes DE, Mammen MJ, Mahajan SD, Schwartz SA. (2016) Galectin-3 in prostate cancer proliferation and metastasis. (Aug)
  • Parikh NU, Mammen MJ, Cumella JC, Rockoff JB, Schwartz SA. (2017) Impact of Lung Flute Therapy on Asthma: A Pilot Study. (Feb)
  • Parikh NU, Aalinkeel R, Reynolds JL, Quaye E, Cwiklinski K, Sykes DE, Mammen MJ, Sharijkova, A, Khmaladze A, Schwartz SA, Mahajan SD. (2017) Methamphetamine (METH) and HIV-tat mediated oxidative stress contributes to Mitochondrial dysfunction in microglia. (Apr)
  • Mammen MJ, Tu, Chengjian, Qu, Jun, Sethi S. (2013) Pathway Analysis Of Bronchoalveolar Lavage Fluid Proteome Of Individuals With COPD Compared To Healthy Controls. (May) A1109
  • Mammen M, Atmar, R, Bandi, V, Greenlee, K, Kheradmand, F. (2010) Proteomic Analysis Of Bronchoalveolar Lavage of Patients with COPD and COPD exacerbation. (May)
  • Bhardwaj A, Savant AC, Tetewsky S, McCray W, Mammen MJ, Khan S, Manion C, Tse ., Liu T, Lee R, Curtis AB, Pershad A, Elkins PL, Corbelli J. (2018) Superior Survival With Direct Oral Anticoagulants Compared to Warfarin in Patients With Atrial Fibrillation and Underlying Cancer: Veterans Affairs Database Study. (Nov)
  • Qin F, Shander A, Mammen MJ, Chuy J, Dardik H. (1999) Treatment of Experimental Acute Severe Anemia with Parental Iron. (Dec)
  • Shander A, Qin F, Mammen MJ, Chuy J, Dardik H. (2000) Treatment of Experimental Acute Severe Anemia with Recombinant Human Erythropoietin. (Jan) A495
See all (5 more)

Professional Memberships:

  • New York State Thoracic Society (2011–present)
  • Society of Critical Care Medicine (2009–present)
  • American College of Chest Physicians (2007–present)
  • American Thoracic Society (2007–present)
  • American College of Physicians (2004–present)
  • American Medical Association (2000–present)
  • American Associations of Physicians of Indian Origin (2000–present)

Presentations:

  • "The tip of the spear, the NYC/NJ COVID-19 experience." COVID-19 Symposium; American Thoracic Society (2020)
  • "Detecting Respiratory Compromise in the PACU" American Academy of Nursing Policy Conference; American Academy of Nursing Policy (2018)
  • "How to Assess for Respiratory Compromise When your patient is on Supplemental Oxygen" American Society of Pain Management Nurses Annual Conference; American Society of Pain Management Nurses (2018)
  • "Occupational Lung Disease" Respiratory and Lung Module; University at Buffalo (2018)
  • "Pulmonary Exam" CPM II (2018)
  • "Asthma COPD management" Webinar; Millenium Collaborative Corporation (2018)
  • "Distinct Airway Microbiome Patterns Associated with Frequent Exacerbator Phenotype in COPD" American Thoracic Society International Conference; American Thoracic Society (2018)
  • "Distinct Airway Microbiome Patterns Associated with Lung Cancer Development in a COPD Cohort" American Thoracic Society international Conference; American Thoracic Society (2018)
  • "Pulmonary Diagnostic Testing" UB Internal Medicine Residency Lecture (2017)
  • "Pulmonary Exam" CPM II (2017)
  • "Approach to Shortness of Breath" UB Internal Medicine Residency Lecture (2017)
  • "Update in Lung Cancer Screening" University at Buffalo Family Medicine Grand Rounds; University at Buffalo; Family Medicine (2017)
  • "Pulmonary Diagnostic Testing" UB Internal Medicine Residency Lecture (2016)
  • "Pulmonary Exam" CPM II (2016)
  • "Approach to Dyspnea" UB IM residency conference; University at Buffalo (2016)
  • "Why are Patients with Pneumonia Readmitted?" American Thoracic Society International Conference; American Thoracic Society (2016)
  • "The Airways Microbiome" City-Wide Grand Rounds; University at Buffalo (2016)
  • "Updates on Lung Cancer Screening Guidelines" American Lung Association: NEW HOPE IN THE FIGHT AGAINST LUNG CANCER; American Lung Association of the Northeast; NEW HOPE IN THE FIGHT AGAINST LUNG CANCER (2016)
  • "Pulmonary Exam" CPM II; University at Buffalo; Medical Students (2015)
  • "Approach to CXR" UB IM residency conference; University at Buffalo (2015)
  • "Approach to Dyspnea" UB IM residency conference; University at Buffalo (2015)
  • "An Update on Lung Cancer Screening: Lung Nodule Management" UBMD Primary Care Update (2015)
  • "Interstitial Lung Disease" Core Didactic Conference; University at Buffalo; Internal Medicine (2014)
  • "Pulmonary Exam" CPM II; University at Buffalo; Medical Students (2013)
  • "A Systems Biology approach to COPD" URMC Pulmonary Conference; University at Rochester; Pulmonary and Critical Care Medicine (2013)
  • "Pulmonary Exam" CPM II; University at Buffalo; Medical Students (2012)
  • "Approach to SOB and Interstitial Lung Disease" Grand Rounds; University at Buffalo; Internal Medicine (2012)
  • "Proteomic analysis of bronchoalveolar lavage of patients with COPD and COPD exacerbations" ATS International Conference; American Thoracic Society; Oral Mini-Symposium (2010)
  • "Nonsleepy OSA" Research Symposium; Baylor College of Medicine; Internal Medicine (2010)
  • "A Clinical Misnomer of Multiple Pulmonary Nodules" ACCP Conference; American College of Chest Physicians; Clinical Case (2009)
  • "A case of Pulmonary Blastoma" Citywide Conference; Baylor College of Medicine; Pulmonary (2008)
  • "A case of Asthma in Pregnancy" Citywide Conference; Baylor College of Medicine; Pulmonary (2008)
  • "A case of Benign Metastazing Leiyomyomata" Citywide Conference; Baylor College of Medicine; Pulmonary (2007)
  • "A case of Cardiac Amyloidosis in an African American male: Transthyretin in the Heart" Grand Rounds; Baylor College of Medicine; Internal Medicine (2007)
  • "A case of Cardiac Amyloidosis in an African American male: Transthyretin in the Heart" Research Symposium; Baylor College of Medicine; Internal Medicine (2007)
  • "Healthcare utilization of sleep apnea patients at the VHA" Research Symposium; Baylor College of Medicine; Internal Medicine (2007)
See all (26 more)

Service Activities:

  • The BMJ- British Medical Journal British Medical Journal peer-reviewer; Peer Reviewer (2020–present)
  • Pharmaceuticals and Therapeutics @ Kaleida Health; Committee Member (2020–present)
  • CHEST journal; Peer Reviewer (2020–present)
  • American Thoracic Society Health Policy Committee member; Committee Member (2017–present)
  • New York State Thoracic Society Poster Session Moderator; Moderator (2017–present)
  • American Thoracic Society Chapter Council Representative NYS representative to ATS, the NYS CCR representative; Councilor (2017–present)
  • BMC Medical Informatics and Decision Making reviewer; Reviewer (2016–present)
  • New York State Thoracic Society Informatics Committee; Chairman (2016–present)
  • PLoS One journal reviewer; Reviewer (2016–present)
  • UBMD EMR committee; Committee Member (2014–2019)
  • Faculty Council; Alternate Member (2014–2020)
  • Journal of Neurological Sciences reviewer; Peer Reviewer (2014–present)
  • Annals of Internal Medicine manuscript reviewer; Peer Reviewer (2014–present)
  • Journal of Inflammation; Peer Reviewer (2013–present)
  • The American Journal of the Medical Sciences/Manuscript Reviewer; Peer Reviewer (2013–present)
  • American Lung Association, WNY Leadership Board; Board Member (2013–2018)
  • Buffalo General Medical Center Patient Safety Committee; Member (2012–2014)
  • American Thoracic Society Clinical Program committee; Member (2012–2013)
  • Independent Health, Palliative Care Taskforce; Advisory Committee (2012–2013)
  • Independent Health, COPD program clinical advisory group; Advisory Committee (2011–2012)
  • New York State Thoracic Society, Executive Board; Member (2011–present)
  • Kaleida Health EMR workgroup; Member (2011–present)
  • Student Family Health Care Center Co-Director The Student Family Health Care Center established after 1967 to meet the needs of the medically underserved, this student-run clinic offers free, quality health care to the Newark community.; Co-Director (2002–2004)

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Contact Information

Buffalo General Medical Center
100 High Street, B-8
Buffalo, New York 14203
Phone: (716) 859-2271
Fax: 7168591491
mammen@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD