University at Buffalo (UB)
Sikandar Z. Khan MBBS, RPVI
Sikandar Z. Khan
MBBS, RPVI
Clinical Assistant Professor of Surgery
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Surgery - Endovascular; Surgery - Vascular
Contact Information
Patient Care
Patient Care
This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.
View this physician on UBMDProfessional Summary:
Clinical expertise:
Endovascular & open surgical treatment of Peripheral arterial disease, Abdominal aortic aneurysms (AAA), Thoracic aneurysms & dissections, Carotid disease & Venous disease and Dialysis access surgery
Vascular surgery has seen great advancement in the last two decades with introduction of minimally invasive endovascular techniques and devices. Vascular surgeons are not only required to stay up-to-date with the newest technologies, but also maintain the highest standards in traditional open surgery. I aim to provide comprehensive care to patients suffering from vascular diseases, including open surgical and minimally invasive treatment of peripheral arterial disease, venous disease, carotid disease, hemodialysis access, abdominal aortic aneurysm (AAA) and thoracic aortic aneurysm at Gates Vascular Institute (GVI)/Buffalo General Hospital and Erie County Medical Center (ECMC). I am also involved in the care of trauma patients suffering from vascular injuries at ECMC.
I also have research interests in various aspects of vascular diseases including peripheral arterial disease and aortic aneurysm disease. Peripheral arterial disease has been my main focus and I have been involved in various studies investigating novel diagnostic and treatment modalities and their impact on our patients. I believe that technology can help us improve patient care but it should be rigorously tested before it is offered to our patients.
Education is an important part of my practice and I train medical students and residents to take care of vascular patients. Some of these trainees will become vascular surgeons, ensuring provision of care to vascular patients in the future.
Education and Training:
- Vascular Surgery Resident, University at Buffalo (2018)
- General Surgery Resident, Yale- New Haven Hospital, Yale School of Medicine (2013)
- Vascular Research Fellow, Columbia University Medical Center (2011)
- Bachelor of Medicine, Bachelor of Surgery (MBBS), King Edward Medical College (2006)
Employment:
- Clinical Assistant Professor of Surgery, Surgery, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2018-present)
Awards and Honors:
- Louis A. and Ruth Siegel Award for teaching- Clinical faculty (2022)
- Clinical Research Award (2016)
- Gold Humanism Honor Society (2016)
Research Expertise:
- Research interests: Peripheral arterial disease, aortic aneurysms, venous diseases, carotid disease.
Grants and Sponsored Research:
- Validation of Plateletcrit as a Marker of Platelet Reactivity by Comparing It with VerifyNow Reactivity Assays
SVS Foundation Clinical Research Seed Grant RESEARCH FOR HEALTH IN ERIE COUNTY, INC
Role: Principal Investigator - University at Buffalo, CTSI Translational Pilot Program-Three-dimensional photoacoustic computed tomography for diagnosis and treatment monitoring of chronic leg ulcers
Role: Co-Investigator - Development of photoacoustic tomography for non-invasive, label-free imaging of tissue perfusion in chronic wounds
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
Role: Co-Investigator
Journal Articles:
- Bhinder J, O'Brien-Irr M, Chang M, Montross B, Khan S, Dosluoglu H, Harris L. (2023) Comparison of success and cost after retrieval of two inferior vena cava filters. J Vasc Surg (Sep) doi:10.1016/j.jvsv.2023.09.001
- Chang M, O'Brien-Irr MS, Shaw JF, Montross BC, Dosluoglu HH, Harris LM, Dryjski ML, Khan SZ. (2023) Optimal medical management in patients undergoing peripheral vascular interventions for chronic limb-threatening ischemia is associated with improved outcomes. J Vasc Surg (May), 2(78): 490-97.
- Chang M, O'Brien-Irr M, Montross B, Dosluoglu H, Harris L, Dryjski M, Rivero M, Khan SZ. Impact. (2023) Impact of Statins on Survival and Limb Salvage in Patients Undergoing Peripheral Endovascular Intervention for Chronic Limb-Threatening Ischemia. Ann Vasc Surg (Apr)(91): 20-27.
- Bhinder J, O'Brien-Irr M, Reilly B, Montross B, Khan S, Rivero M, Cherr G, Harris L. (2023) Understanding radiation exposure and improving safety for vascular surgery trainees. J Vasc Surg (Jan), 1(77): 269-278.
- Oh K, O'Brien-Irr MS, Montross BC, Khan SZ, Dryjski ML, Dosluoglu HH, Rivero M, Harris LM. (2023) Comparison of outcomes for balloon angioplasty, atherectomy, and stenting in the treatment of infrapopliteal disease for chronic limb-threatening ischemia. J Vasc Surg (Jan), 1(77): 241-247.
- Khan SZ, O'Brien-Irr MS, Fakhoury E, Montross B, Rivero M, Dosluoglu HH, Harris LM, Dryjski ML. (2022) P2Y12 inhibitor monotherapy is associated with superior outcomes as compared with aspirin monotherapy in chronic limb-threatening ischemia. J Vasc Surg (Oct), 4(76): 1053-1059.
- Montross BC, O' Brien-Irr MS, Khan SZ, Dosluoglu HH, Rivero M, Harris LM, Cherr G, Dryjski ML. (2022) Need for Routine Preoperative Insertion of Indwelling Urinary Catheter Prior to Endovascular Repair of Abdominal Aortic Aneurysm. Ann Vasc Surg (May)
- Ahuja N, Bhinder J, Nguyen J, Langan T Jr, O'Brien-Irr M, Montross B, Khan S, Sharma AM, Harris LM. (2021) Venous thromboembolism in patients with COVID-19 infection: risk factors, prevention, and management. Semin Vasc Surg (Sep)
- Montross BC, O‘Brien-Irr MS, Koudoumas D, Khan SZ, Rivero M, Harris LM, Dosluoglu HH, Cherr GS, Dryjski ML. (2020) The selection of patients for ambulatory endovascular aneurysm repair of elective asymptomatic abdominal aortic aneurysm. J Vasc Surg (Oct), 72(4): 1347-1353.
- Khan SZ, Dosluoglu HH, Pourafkari L, Rivero M, Nader ND. (2020) High plateletcrit is associated with early loss of patency after open and endovascular interventions for chronic limb ischemia. J Vasc Surg (Jun), 71(6): 2089-2097.
- Khan SZ, O'Brien-Irr MS, Rivero M, Blochle R, Cherr GS, Dryjski ML, Dosluoglu HH, Lukan J, Rowe VL, Harris LM. (2020) Improved survival with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in chronic limb-threatening ischemia. J Vasc Surg (Apr)
- Khan SZ, Montross B, Rivero M, Cherr GS, Harris LM, Dryjski ML, Dosluoglu HH. (2020) Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers (ACEI/ARB) are Associated with Improved Limb Salvage after Infrapopliteal Interventions for Critical Limb Ischemia. Ann Vasc Surg (Feb), 63: 275-286.
- Reilly B, Khan S, Dosluoglu H, Harris L, O'Brien-Irr M, Lukan J, Dryjski M, Blochle R. (2019) Comparison of Autologous Vein and Bovine Carotid Artery Graft as a Bypass Conduit in Arterial Trauma. Annals of Vascular Surgery (Nov)
- Dosluoglu HH, Rivero M, Khan SZ, Cherr GS, Harris LM, Dryjski ML. (2019) Pre-emptive nonselective perigraft aortic sac embolization with coils to prevent type II endoleak after endovascular aneurysm repair. J Vasc Surg (Jun), 69(6): 1736-1746.
- Wang Y, Zhan Y, Harris LM, Khan S, Xia J. (2019) A Portable Three-Dimensional Photoacoustic Tomography System for Imaging of Chronic Foot Ulcers. Quant Imaging Med Surg. (May)
- Khan SZ, Rivero M, Nader ND, Cherr G, Harris LM, Dryjski ML, Dosluoglu HH. (2019) Metformin Is Associated with Improved Survival and Decreased Cardiac Events with No Impact on Patency and Limb Salvage after Revascularization for Peripheral Arterial Disease. Ann Vasc Surg (Feb), 55: 63-77.
- Khan SZ, Rivero M, Cherr GS, Harris LM, Dryjski ML, Dosluoglu HH. (2018) Long-term Durability of Infrainguinal Endovascular and Open Revascularization for Disabling Claudication. Ann Vasc Surg (May)
- Khan SZ, Dosluoglu HH. (2018) Should Multiple Vessels be Recanalised for Tissue Loss Irrespective of Pedal Anatomy and Angiosome?. Eur J Vasc Endovasc Surg (Apr), 55(4): 528-528.
- Khan SZ, Rivero M, McCraith B, Harris LM, Dryjski ML, Dosluoglu HH. (2016) Endoscopic vein harvest does not negatively affect patency of great saphenous vein lower extremity bypass. J Vasc Surg (Jan), 63(6): 1546-1554.
- Meltzer AJ, Shrikhande G, Gallagher KA, Aiello FA, Khan S, Connolly P, McKinsey JF, K. (2012) Heart failure is associated with reduced patency after endovascular intervention for symptomatic peripheral arterial disease. J Vasc Surg (Feb), 55(2): 353-362.
- Shrikhande GV, Khan SZ, Meltzer AJ, Gallagher K, Morrissey NJ. (2011) Endovascular management of type B aortic dissection after attempted central venous catheterization. Ann Vasc Surg (Oct), 25(7): 979-979.
- Khan SZ, Khan MA, Bradley B, Dayal R, McKinsey JF, Morrissey NJ. (2011) Utility of duplex ultrasound in detecting and grading de novo femoropopliteal lesions. J Vasc Surg (Oct), 54(4): 1067-1073.
- Shrikhande GV, Khan SZ, Hussain HG, Dayal R, McKinsey JF, Morrissey N. (2011) Lesion types and device characteristics that predict distal embolization during percutaneous lower extremity interventions. J Vasc Surg (Feb), 53(2): 347-352.
- Shrikhande GV, Khan SZ, Gallagher K, Morrissey NJ. (2011) Endovascular management of superior mesenteric artery pseudoaneurysm. J Vasc Surg (Jan), 53(1): 209-211.
- Hussain HG, Aparajita R, Khan SZ, Rezayat C, McKinsey JF, Dayal R. (2011) Closed-cell stents present with higher velocities on duplex ultrasound compared with open-cell stents after carotid intervention: short- and mid-term results. Ann Vasc Surg (Jan), 25(1): 55-63.
- Shrikhande GV, Khan SZ, Hussain HG, Menezes A, McKinsey JF, Bush HL. (2010) Significance of Initial Aortic Aneurysm Pressure Sensor Readings Varies With Aortic Endograft Design. World Journal of Surgery (Dec), 34(12): 2969-2972.
Books and Book Chapters:
- Sikandar Khan, Hasan Dosluoglu. (2022) Complex Regional Pain Syndrome. In: Rutherford's Vascular Surgery and Endovascular Therapy, 2-Volume Set, 10th Edition.
- Sikandar Z. Khan, Nicolas J. Mouawad, Richard Curl. (2020) Endologix AFX. In: Complications in Endovascular Surgery.
- Sikandar Z. Khan, Richard Curl. (2020) Endologix Ovation. In: Complications in Endovascular Surgery.
- Sikandar Khan, Hasan Dosluoglu. (2020) Infra-Inguinal Arterial Occlusive Disease. In: Vascular Decision Making.
Professional Memberships:
- Eastern Vascular Society (EVS); Member (2015–present)
- Society for Vascular Surgery (SVS); Member (2015–present)
- Western New York Vascular Society; Member (2013–present)
Presentations:
- "Allografts for Lower Extremity." LeMaitre North American Meeting (2024)
- "Aortoiliac atherosclerotic occlusive disease (AIOD)." Western NY Vascular Society Annual Symposium (2023)
- "Use of Artegraft in Extremity Vascular Trauma" LeMaitre North American Meeting (2023)
- "Use of Biological Grafts in Extremity Vascular Trauma" LeMaitre 2022 North American Meeting. January 2022 (2022)
- "Chronic Limb Threatening Ischemia (CLTI) Diagnosis and Management" UB Department of Surgery Grand Rounds (2021)
- "Management of aortic ectasia- Can we slow it down with medical management?" Western New York Vascular Society Symposium (2020)
- "Evaluation of a patient with a swollen leg: What can a vascular surgeon offer?" Gates Vascular Institute Symposium (2019)
- "Improved Survival and Amputation-Free Survival with Angiotensin Converting Enzyme Inhibitors & Angiotensin Receptor Blockers (ACE/ARB) in Patients Undergoing Endovascular Interventions (EVI) For Critical Limb Ischemia (CLI)." Vascular and Endovascular Surgery Society (VESS) Spring Meeting (2019)
- "Aneurysms and Occlusions: An update on management of PAD and AAA" UB Family Medicine Rounds (2019)
- "Inferior vena cava (IVC) filter: Insertion and retrieval." Western New York Vascular Society Symposium (2019)
- "Acute Limb ischemia: Diagnosis and management" Gates Vascular Institute Symposium (2018)
- "Plateletcrit Is Associated with Early Loss of Patency after Open and Endovascular Interventions for Chronic Limb Ischemia" SVS Annual Meeting 2018 (2018)
- "Metformin Is Associated with Improved Survival and Decreased Cardiac Events With No Impact on Patency and Limb Salvage After Revascularization for Peripheral Arterial Disease" EVS Annual Meeting 2017 (2017)
- "Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers (ACEI/ARB) are Associated with Improved Limb Salvage After Infrapopliteal Interventions for Critical Limb Ischemia" SCVS Annual Meeting 2017 (2017)
- "Predicting Outcomes Following Lower Extremity Revascularization For Critical Limb Ischemia With Tissue Loss Using a Modified Wound, Ischemia, foot Infection Classification System (mWIfI)." EVS Annual Meeting 2016 (2016)
- "Long Term Durability of Infrainguinal Endovascular and Open Revascularization for Disabling Claudication." VAST3 2016 (2016)
- "Increased Role of Drug-eluting and Self-expanding Stents in Patients with Severe Infrapopliteal Disease." SCVS Annual Meeting 2016 (2016)
- "Endoscopic Vein Harvest (EVH) Does Not Negatively Impact Patency of Great Saphenous Vein (GSV) Lower Extremity Bypass" EVS Annual Meeting 2015 (2015)
- "The Obesity Paradox And Outcomes Of Lower Extremity Endovascular Interventions; Is Obesity Protective?" American Heart Association Scientific Sessions 2010 (2011)
- "Continued Smoking Has A Significant Negative Impact On Lower Extremity Endovascular Intervention Outcomes In The Long Term" Eastern Vascular Society 24th Annual Meeting; (2010)
- "Duplex Criteria For Detecting De Novo Femoropopliteal Lesions" NEVS Annual Meeting 2010 (2010)
- "Outback® Re-entry Catheter; Enables The Safe Endovascular Management Of Complex Chronic Total Occlusions" Midwestern Vascular Society 2010-34th Annual Meeting (2010)
Service Activities:
- Kickstart Foot Care- Free foot care and legal services to the senior community in collaboration with Center for Elder Law & Justice. At Moot Senior Center, Buffalo, NY. June 3, 2023,; Faculty volunteer (2023–2024)
- Western New York Vascular Society; President (2023–present)
- Eastern Vascular Society; Member Research Committee (2022–present)
- Journal of Vascular Surgery; Reviewer (2022–present)
- General Surgery Clinical Competency Committee; Faculty member (2021–present)
- Vascular Surgery Clinical Competency Committee; Faculty member (2018–present)