Researchers in the Department of Microbiology and Immunology have developed a new, statistically more powerful method that can more effectively detect key functional pathways in cancer using genomics data generated by next-generation sequencing technology.
Research by Gabriela K. Popescu, PhD, professor of biochemistry, has revealed that the absence of a single interaction within a brain receptor reduces its activity. The discovery advances the understanding of how certain brain diseases arise, and could lead to developing precision medicines for treating them.
Thomas D. Grant, PhD, assistant professor of structural biology, is co-principal investigator on a grant from the National Science Foundation (NSF) to study how small molecules bind to the SARS-COV-2 protease to understand drug binding and help aid drug design.
Memory loss associated with Alzheimer’s disease may be able to be treated by inhibiting certain enzymes involved in abnormal gene transcription, according to a preclinical study led by senior author Zhen Yan, PhD.
At the start of the pandemic, research teams around the world began conducting studies to help further research related to vaccines for the SARS-CoV-2 coronavirus. A team led by Jonathan F. Lovell, PhD, was one of them.
Bruce R. Troen, MD, professor of medicine and chief of the Division of Geriatrics and Palliative Medicine, wants people to know that a study published this month in the Annals of Internal Medicine — which shows no benefit from higher doses of vitamin D in the frail elderly — is not the final chapter on how vitamin D affects this population.
Joseph Terrell Smith Jr., PhD, postdoctoral fellow in microbiology and immunology, has been awarded a three-year, $202,000 F32 grant from the National Institute of Allergy and Infectious Diseases to study the regulation of RNA in Trypanosoma brucei.