Michael E. Cain MD
Michael E. Cain
MD
Vice President for Health Sciences and Dean, Jacobs School of Medicine and Biomedical Sciences
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Cardiology; Cardiovascular Disease; Clinical Cardiac Electrophysiology; Internal Medicine
Professional Summary:
An internationally recognized cardiovascular physician-scientist, Dr. Cain is a specialist in abnormal heart rhythms. He is board-certified in internal medicine, cardiovascular diseases and clinical cardiac electrophysiology and pacing. He is a fellow of the American College of Cardiology, the American Heart Association and the Heart Rhythm Society.
A former associate editor of Circulation, Cain is a member of the editorial boards of the American Journal of Cardiology, the Journal of Cardiovascular Electrophysiology, Nature Clinical Practice Cardiovascular Medicine and Heart Rhythm.
His NIH-supported research has focused on determining the mechanisms of life-threatening heart rhythm abnormalities that occur in heart attacks and other conditions that damage heart muscle cells. This information is being used to better characterize and more accurately localize the abnormal heart tissue responsible for these abnormal heart rhythms and to improve the identification of patients at increased risk for sudden cardiac death.
Education and Training:
- Fellowship, Clinical Cardiac Electrophysiology Laboratory, Cardiovascular Section, University of Pennsylvania School of Medicine (1981)
- Fellowship, Clinical Cardiology, Cardiovascular Division, Barnes Hospital, Washington University School of Medicine (1980)
- Fellowship, Cardiovascular Division, Washington University School of Medicine (1978)
- Residency, Washington University School of Medicine, Barnes Hospital (1977)
- Internship, Medicine, Washington University School of Medicine, Barnes Hospital (1976)
- MD, George Washington University School of Medicine (1975)
- BA, Gettysburg College, Cum Laude (1971)
Employment:
- Vice President, University at Buffalo, Health Sciences (2011-present)
- Professor of Biomedical Engineering, Biomedical Engineering, University at Buffalo (2010-present)
- Dean, Jacobs School of Medicine and Biomedical Sciences, Dean‘s Office, University at Buffalo (2006-present)
- Professor of Medicine, Medicine, University At Buffalo (2006-present)
- Professor of Chemical and Biological Engineering, Chemical and Biological Engineering, University at Buffalo (2007–2010)
- President, Board of Directors, Heart Care Institute, Washington University School of Medicine, Barnes-Jewish Hospital (2000–2006)
- Professor of Biomedical Engineering, Medicine, Washington University School of Medicine (1999–2006)
- Tobias and Hortense Lewin Professor of Medicine, Medicine, Washington University School of Medicine (1994–2006)
- Visiting Professor, Albert Einstein University/Montefiore Hospital (2005)
- Visiting Professor, University of Minnesota (2005)
- Visiting Professor, Northwestern University (2005)
- Visiting Professor, University of Arkansas (2004)
- Visiting Professor, University of Pennsylvania (2004)
- Visiting Professor, Johns Hopkins University (2004)
- Visiting Professor, University of California San Diego (2003)
- Visiting Professor, University of Missouri (2002)
- Visiting Professor, University of Claifornia San Diego (2002)
- Visiting Professor, University of Kansas (2002)
- Visiting Professor, University of Oklahoma (2002)
- Visiting Professor, University of Kansas (2001)
- Visiting Professor, University of Texas Southwestern (2001)
- Visiting Professor, University of Pennsylvania (2001)
- Visiting Professor, University of Minnesota (1999)
- Visiting Professor, Cleveland Clinic Foundation (1998)
- Visiting Professor, University of Pittsburgh (1997)
- Visiting Professor, Texas Heart Institute (1997)
- Visiting Professor, Hershey Medical Center (1997)
- Visiting Professor, University of Pennsylvania (1997)
- Director, Cardiovascular Division, Washington University School of Medicine, Barnes-Jewish Hospital (1994–1996)
- Director, Arrhythmia Services, Washington University School of Medicine, Barnes-Jewish Hospital (1994–1996)
- Visiting Professor, Hahneman University (1995)
- Visiting Professor, University of Louisville (1995)
- Visiting Professor, University of South Florida (1994)
- Visiting Professor, University of Iowa (1994)
- Interim Director, Cardiovascular Division, Washington University School of Medicine, Washington University School of Medicine (1993–1994)
- Professor of Medicine, Medicine, Washington University School of Medicine, Washington University School of Medicine (1993–1994)
- Director, Clinical Cardiac Electrophysiology Laboratory, Washington University School of Medicine, Barnes Hospital (1981–1994)
- Visiting Professor, Northwestern University (1993)
- Associate Professor of Medicine, Medicine, Washington University School of Medicine, Washington University School of Medicine (1987–1993)
- Visiting Professor, University of Louisville (1992)
- Visiting Professor, Dalhousie University, Canada (1992)
- Visiting Professor, University of Toronto, Canada (1992)
- Visiting Professor, University of California San Diego (1992)
- Visiting Professor, University of Nebraska (1991)
- Visiting Professor, University of Tennessee (1991)
- Visiting Professor, University of Iowa (1991)
- Visiting Professor, University of Louisville (1991)
- Visiting Professor, Harvard Medical School, Brigham and Womens Hospital (1991)
- Visiting Professor, Medical College of Wisconsin (1990)
- Visiting Professor, University of Alabama (1989)
- Visiting Professor, State University of New York (1989)
- Visiting Professor, University of Nebraska (1989)
- Visiting Professor, University of Missouri (1989)
- Visiting Professor, University of Minnesota (1989)
- Visiting Professor, Creighton University (1989)
- Visiting Professor, Hahneman University (1989)
- Visiting Professor, University of Kansas City (1989)
- Visiting Professor, University of California San Diego (1989)
- Visiting Professor, University of Rochester (1989)
- Visiting Professor, University of Minnesota (1987)
- Visiting Professor, University of Kansas Medical Center (1987)
- Visiting Professor, Medical College of Wisconsin (1987)
- Visiting Professor, UMDNJ-Rutgers Medical School (1987)
- Assistant Professor of Medicine, Medicine, Washington University School of Medicine, Washington University School of Medicine (1981–1987)
- Visiting Professor, University of California Davis (1986)
- Visiting Professor, University of London, Canada (1984)
Awards and Honors:
- Distinguished Fellowship Award, 18th World Congress on Heart Disease, International Academy of Cardiology (2013)
- Leadership Buffalo Value Award for Inclusion (2013)
- Stanley J. Sarnoff Spirit Award, Sarnoff Cardiovascular Research Foundation (2012)
- Resident/Fellow Alumni Achievement Award, Washington University Medical Ctr (2012)
- American Clinical and Climatological Association (2012)
- Distinguished Service Award, Heart Rhythm Society (2007)
- Distinguished Service Teaching Award, Washington University Medical School (2006)
- Hans-Peter Krayenbuehl Memorial Award for Research in Cardiac Function (2005)
- Distinguished Service Teaching Award, Washington University Medical School (2005)
- Fellow, Heart Rhythm Society (2003)
- American Heart Association Heart Ball Medical Honoree, St. Louis Chapter (2002)
- Outstanding Researcher of the Year Award, Missourian American Heart Assoc. (2002)
- Arthur E. Strauss Award, American Heart Association (2000)
- Fellow, Council on Clinical Cardiology of the American Heart Association (1985)
- Fellow, American College of Cardiology (1984)
- University Teacher of the Year Award (1982)
- American Heart Association Fellowship Award (1980)
- Calvin Klopp Award, William Beaumont Medical Research Society (1975)
- Alpha Omega Alpha (1974)
- Washington Heart Association Student Research Grant (1973)
- William Beaumont Medical Research Society, Washington University (1972)
- George B. Stoner Award, Gettysburg College (1971)
Research Expertise:
- Risk stratification for sudden cardiac death
UB 2020 Strategic Strengths:
- Molecular Recognition in Biological Systems and Bioinformatics
- Integrated Nanostructured Systems
- Health and Wellness Across the Lifespan
- Extreme Events: Mitigation and Response
- Civic Engagement and Public Policy
Grants and Sponsored Research:
- January 2006–January 2011
Principles in Cardiovascular Research Training Program
NIH National Heart, Lung and Blood Institute
Role: Principal Investigator
$1,999,987 - January 2005–January 2009
Clinical Research Skills Development
NIH National Heart, Lung and Blood Institute, Core SCCOR in Cardiac Dysfunction and Disease
Role: Principal Investigator
$471,004 - January 2006–December 2007
Remodeling and novel biomarkers of cardiovascular disease in Type 2 diabetes
Washington University/Pfizer Biomedical Research Program
Role: Co-Investigator
$2,050,249 - January 2001–January 2006
Principles in Cardiovascular Research Training Program
NIH National Heart, Lung and Blood Institute
Role: Principal Investigator
$1,636,895 - January 2001–January 2004
The Pathophysiology of T-wave Alternans
Sponsor: Sanjiv Narayan, M.D.
Role: Principal Investigator
$616,895 - January 1998–January 2003
Pathophysiologic Basis of Ventricular Tachycardia in Man
NIH National Heart, Lung and Blood Institute
Role: Principal Investigator
$692,154 - January 1996–January 2001
Principles in Cardiovascular Research Training Program
NIH National Heart, Lung and Blood Institute
Role: Principal Investigator
$1,160,430 - January 1992–January 1998
Multicenter Unsustained Tachycardia Trial - MUSTT
NIH National Heart, Lung, and Blood Institute
Role: Principal Investigator
$107,460 - January 1993–January 1997
Pathophysiologic Basis of Ventricular Tachycardia in Man
NIH National Heart, Lung and Blood Institute
Role: Principal Investigator
$753,331 - January 1995–January 1996
Mechanisms of nonsustained ventricular tachycardia in humans
American Heart Association Fellowship Award, Missouri Affiliate
Role: Principal Investigator
$28,000 - January 1991–January 1995
Principles in Cardiovascular Research Training Program
NIH National Heart, Lung, and Blood Institute
Role: Co-Investigator
$2,584,285 - January 1990–December 1994
Determinants of altered frequency components in electrocardiographic signals
NIH Heart, Lung, and Blood Institute, SCOR-Ischemic Heart Disease
Role: Co-Investigator
$653,344 - January 1992–January 1993
Contribution of dynamic changes in repolarization to the termination of nonsustained ventricular tachycardia
Michael Bilitch Fellowship in Cardiac Pacing and Electrophysiology
Role: Principal Investigator - January 1992–January 1993
An open, multicenter evaluation of the Bard radiofrequency energy catheter ablation system in the treatment of patients with sympotomatic, sustained ventricular tachycardias using abnormal atrioventricular conduction pathways
Bard Electrophysiology
Role: Principal Investigator
$35,000 - January 1989–December 1992
A linkage study of long QT syndrome in an Amish kindred
National Institutes of Health
Role: Co-Investigator
$752,281 - January 1991–January 1992
A randomized, double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with refractory, hemodynamically destabilizing ventriuclar tachycardia or fibraillation
Wyeth-Ayerst and North American Society of Pacing and Electrophysiology
Role: Co-Investigator
$71,881 - January 1990–January 1992
Clinical investigation of Medtronic 7216A/17B Pacer-Cardioverter-Defibrillator (PCD) system
Medtronic, Inc.
Role: Co-Investigator
$20,000 - January 1986–December 1991
Mechanisms of arrhythmogenesis following infarction
NIH National Heart, Lung, and Blood Institute
Role: Co-Investigator
$1,355,970 - January 1990–January 1991
A dose-ranging study of intravenous amiodarone in patients with refractory ventricular tachycardia/fibrillation
Wyeth-Ayerst
Role: Co-Investigator
$39,496 - January 1990–January 1991
Electrophysiologic determinants of altered frequency components in signal-averaged ECGs
Missouri American Heart Association Fellowship
Role: Principal Investigator
$23,000 - January 1989–January 1990
Contributions and therapeutic implications of primary repolarization abnormalities in the initiation of ventricular arrhythmias by programmed stimulation
Kenneth M. Rosen Fellowship in Cardiac Pacing and Electrophysiology, North American Society of Pacing and Electrophysiology
Role: Principal Investigator
$28,000 - January 1988–January 1990
A comparative inpatient study of the safety and efficacy of three oral Recainam doses in the suppression of life-threatening ventricular tachyarrhythmias
Berlex Laboratories
Role: Principal Investigator
$52,800 - January 1988–January 1990
Emergency use of intravenous amiodarone in patients with refractory ventricular tachycardia/fibrillation
Wyeth-Ayerst
Role: Co-Investigator
$8,000 - January 1988–January 1990
A placebo controlled study of ascending single oral doses of CK-1752A in patients with frequent ventricular ectopy to examine safety, pharmacodynamics and pharmakinetics
Berlex Laboratories
Role: Principal Investigator
$48,178 - January 1985–December 1989
Effects of phychosocial and psychoeducational interventions on compliance to beta-adrenergic blocking agents in patients recovering from acute myocardial infarction and to antiarrhythmic agents for prevention of sudden cardiac death
NIH, National Research and Demonstration Center Component SCOR-Ischemic Heart Disease
Role: Co-Investigator
$954,941 - January 1984–December 1989
Detection of the risks of malignant ventricular arrhythmia and assessment of its response to medical and surgical intervention
NIH, National Heart, Lung, and Blood Institute, SCOR-Ischemic Heart Disease
Role: Co-Investigator
$699,939 - January 1988–January 1989
Electrophysiologic and morphologic determinants of intramural reentry in human ventricular tachycardia
Michael Bilitch Fellowship in Cardiac Pacing and Electrophysiology, North American Society of Pacing and Electrophysiology
Role: Principal Investigator
$23,500 - January 1987–January 1989
A double-blind multicenter comparison of intravenous adenosine to intravenous placebo in the termination of spontaneous or induced paroxysmal supraventricular tachycardia
Medco Research
Role: Co-Investigator
$11,050 - January 1987–January 1988
Fast Fourier Transform Analysis of signal-averaged ECG complexes: a potential noninvasive approach to the identification of patients at risk for the development of ventricular tachycardia
Washington University School of Medicine
Role: Principal Investigator
$9,682 - January 1987–January 1988
A dose-range evaluation of the myocytic alpha-adrenergic receptor blocking potential of Labetalol
Glaxo Laboratories
Role: Principal Investigator
$20,095 - January 1980–January 1981
Evaluation of ventricular excitabiliy in man
American Heart Association Fellowship Award
Role: Principal Investigator
$8,250
Journal Articles:
- Goldberger JJ, Basu A, Boineau R, Buxton AE, Cain ME, Canty JM Jr, Chen PS, Chugh SS, Costantini O, Exner DV, Kadish AH, Lee B, Lloyd-Jones D, Moss A, Myerburg R, Olgin J, Passman R, Stevenson W, Tomaselli G, Zareba W, Zipes DP and Zoloth L. Risk stratification for sudden cardiac death: A plan for the future. Circulation. 2014; 129.
- Fallavollita JA, Heavey BM, Luisi AJ Jr, Michalek SM, Baldwa S, Mashtare TL, Hutson AD, deKemp RA, Haka MS, Sajjad M, Cimato TR, Curtis AB, Cain ME and Canty JM Jr.. Regional myocardial sympathetic denervation predicts the risk of sudden cardiac arrest in ischemic cardiomyopathy. J Am Coll Cardiol. 2014; 63.
- Goldberger JJ, Basu A, Boineau R, Buxton AE, Cain ME, Canty J, Chen PS, Chugh SS, Costantini O, Exner DV, Kadish AH, Lee B, Lloyd-Jones D, Moss A, Myerburg R, Olgin J, Passman R, Stevenson W, Tomaselli G, Zareba W, Zipes DP, Zoloth L. Risk Stratification for Sudden Cardiac Death: A Plan for the Future. Circulation. 2014; 129.
- Zhang Z, Rautaherju PM, Soliman EZ, Manson JE, Cain ME, Curb JD, Martin LW, Bavry A, Metha L, Vitolins M, Prineas RJ. Mortality Risk Associated with Bundle Branch Blocks and Related Repolarization Abnormalities (From the Women’s Health Initiative [WHI]).. Am J Cardiol. 2012; 110.
- Albert CM, Chen PS, Anderson ME, Cain ME, Fishman GI, Narayan SM, Olgin JE, Spooner PM, Stevenson WG, Van Wagoner DR, Packer DL. Full report from the first annual Heart Rhythm Society Research Forum: a vision for our research future, "dream, discover, develop, deliver". Heart Rhythm. 2011; 8(12).
- Goldberger JJ, Buxton AE, Cain ME, Costantini O, Exner DV, Knight BP, Lloyd-Jones D, Kadish AH, Lee B, Moss A, Myerburg R, Olgin J, Passman R, Rosenbaum D, Stevenson W, Zareba W, Zipes DP. Risk stratification for arrhythmic sudden cardiac death: identifying the roadblocks. Circulation. 2011; 123(21).
- Beck H, Boden WE, Patibandla S, Kireyev D, Gutpa V, Campagna F, Cain ME, Marine JE. 50th Anniversary of the first successful permanent pacemaker implantation in the United States: historical review and future directions. Am J Cardiol. 2010; 106(6).
- Goldberger JJ, Cain ME, Hohnloser SH, Kadish AH, Knight BP, Lauer MS, Maron BJ, Page RL, Passman RS, Siscovick D, Stevenson WG, Zipes DP. American Heart Association/american College of Cardiology Foundation/heart Rhythm Society scientific statement on noninvasive risk stratification techniques for identifying patients at risk for sudden cardiac death: a scientific statement from the Americ Heart Rhythm. 2008; 5(10).
- Cain ME, Curtis AB. Rhythm control in atrial fibrillation--one setback after another. N Engl J Med. 2008; 358(25).
- Greenberg SL, Mauricio Sánchez J, Cooper JA, Cain ME, Chen J, Gleva MJ, Lindsay BD, Smith TW, Faddis MN. Sustained polymorphic arrhythmias induced by programmed ventricular stimulation have prognostic value in patients receiving defibrillators. Pacing Clin Electrophysiol. 2007; 30(9).
- Smith TW, Cain ME. Sudden cardiac death: epidemiologic and financial worldwide perspective. J Interv Card Electrophysiol. 2006; 17(3).
- Carlson MD, Wilkoff BL, Maisel WH, Carlson MD, Ellenbogen KA, Saxon LA, Prystowsky EN, Alpert JS, Cain ME, Ching EA, Curtis AB, Davies DW, Hammill SC, Hauser RG, Lampert R, Zipes DP, Curtis A. Recommendations from the Heart Rhythm Society Task Force on Device Performance Policies and Guidelines Endorsed by the American College of Cardiology Foundation (ACCF) and the American Heart Association (AHA) and the International Coalition of Pacing and Heart Rhythm. 2006; 3(10).
- Narayan SM, Smith JM, Lindsay BD, Cain ME, Dávila-Román VG. Relation of T-wave alternans to regional left ventricular dysfunction and eccentric hypertrophy secondary to coronary heart disease. Am J Cardiol. 2006; 97(6).
- Cain ME. Primary prevention of sudden cardiac death: one step forwards and one step backwards. Nat Clin Pract Cardiovasc Med. 2006; 3(3).
- Narayan SM, Smith JM, Cain ME. T-wave alternans using ventricular and atrial pacing. Pacing Clin Electrophysiol. 2005; 28(10).
- Cain ME. Normal sinus rhythm without the normal atrial kick. Heart Rhythm. 2005; 2(9).
- Narayan SM, Smith JM, Schechtman KB, Lindsay BD, Cain ME. T-wave alternans phase following ventricular extrasystoles predicts arrhythmia-free survival. Heart Rhythm. 2005; 2(3).
- Hammill SC, Cain ME. Alternate training track for ICD and CRT implantation for non-electrophysiologists: are the guidelines too strict to be practical or too simple to protect patient care? Heart Rhythm. 2004; 1(3).
- Curtis AB, Ellenbogen KA, Hammill SC, Hayes DL, Reynolds DW, Wilber DJ, Cain ME. Clinical competency statement: Training pathways for implantation of cardioverter defibrillators and cardiac resynchronization devices. Heart Rhythm. 2004; 1(3).
- Rogers JG, Cain ME. Electromechanical associations. N Engl J Med. 2004; 350(21).
- Cain ME. NASPE-Heart Rhythm Society: State-of-the-Society. J Cardiovasc Electrophysiol. 2004; 15.
- Faddis MN, Chen J, Osborn J, Talcott M, Cain ME, Lindsay BD. Magnetic guidance system for cardiac electrophysiology: a prospective trial of safety and efficacy in humans. J Am Coll Cardiol. 2003; 42(11).
- Cain ME, Arthur RM, Trobaugh JW. Detection of the fingerprint of the electrophysiological abnormalities that increase vulnerability to life-threatening ventricular arrhythmias. J Interv Card Electrophysiol. 2003; 9(2).
- Cain ME, Faddis MN. Mapping atrial fibrillation. Uncertainty despite resolution. J Am Coll Cardiol. 2003; 42(2).
- Cain ME. Atrial fibrillation--rhythm or rate control. N Engl J Med. 2002; 347(23).
- Gomes JA, Cain ME, Buxton AE, Josephson ME, Lee KL, Hafley GE. Prediction of long-term outcomes by signal-averaged electrocardiography in patients with unsustained ventricular tachycardia, coronary artery disease, and left ventricular dysfunction. Circulation. 2001; 104(4).
- Cain ME. Distribution of spectralenergy on the body surface: a physiological road map to improve identification of patients vulnerable to sustained ventricular arrhythmias. Eur Heart J. 1999; 20.
- Pogwizd SM, McKenzie JP, Cain ME. Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy. Circulation. 1998; 98(22).
- Narayan SM, Cain ME, Smith JM. Atrial fibrillation. Lancet. 1997; 350(9082).
- Pogwizd SM, Chung MK, Cain ME. Termination of ventricular tachycardia in the human heart. Insights from three-dimensional mapping of nonsustained and sustained ventricular tachycardias. Circulation. 1997; 95(11).
- Chung MK, Pogwizd SM, Miller DP, Cain ME. Three-dimensional mapping of the initiation of nonsustained ventricular tachycardia in the human heart. Circulation. 1997; 95(11).
- Baker BM, Lindsay BD, Bromberg BI, Frazier DW, Cain ME, Smith JM. Catheter ablation of clinical intraatrial reentrant tachycardias resulting from previous atrial surgery: localizing and transecting the critical isthmus. J Am Coll Cardiol. 1996; 28(2).
- Cain ME, Anderson JL, Arnsdorf MF, Mason JW, Scheinman MM, Waldo AL. American College of Cardiology Expert Consensus Document. Signal-averaged electrocardiography. J Am Coll Cardiol. 1996; 27.
- Bromberg DI, Lindsay BD, Cain ME, Cox JL. Impact of clinical history and electrophysiologic characterization of accessory pathways on management strategies to reduce sudden death among children with Wolff-Parkinson-White syndrome. J Am Coll Cardiol. 1996; 27.
- Beetner DG, Ambos HD, Cain ME, Arthur RM. Determination of epicardial potentials using aimed lead. Medical & Biological Engineering & Computing. 1996; 34.
- Baker BM, Smith JM, Cain ME. Nonpharmacologic approaches to the treatment of atrial fibrillation and atrial flutter. J Cardiovasc Electrophysiol. 1995; 6(10 Pt).
- Cox JL, Boineau JP, Schuessler RB, Kater KM, Ferguson TB, Cain ME, Lindsay BD, Smith JM, Corr PB, Hogue CB. Electrophysiologic basis, surgical development, and clinical results of the maze procedure for atrial flutter and atrial fibrillation. Adv Card Surg. 1995; 6.
- Arthur RM, Kavesh NG, Ambos HD, Cain ME. Phase and group-delay characteristics of signal-averaged electrocardiograms from patients with ventricular tachycardia. IEEE Trans Biomed Eng. 1995; 42(1).
- Frazier DW, Cain ME. Advances in antitachycardia pacing for ventricular tachycardia. ACC Current Journal Review. 1995.
- Aton EA, Murray P, Fraser V, Conaway L, Cain ME. Safety of reusing cardiac electrophysiology catheters. Am J Cardiol. 1994; 74(11).
- Kavesh NG, Cain ME, Ambos HD, Arthur RM. Enhanced detection of distinguishing features in signal-averaged electrocardiograms from patients with ventricular tachycardia by combined spatial and spectral analyses of entire cardiac cycle. Circulation. 1994; 90(1).
- Rokkas CK, Nitta T, Schuessler RB, Branham BH, Cain ME, Boineau JP, Cox JL. Human ventricular tachycardia: precise intraoperative localization with potential distribution mapping. Ann Thorac Surg. 1994; 57(6).
- Arthur RM, Kavesh NG, Ambos HD, Cain ME. Spectral analysis of the cardiac cycle of signal-averaged Frank leads from patients with ventricular tachycardia. J Electrocardiol. 1994; 27 Su.
- Prager NA, Cox JL, Lindsay BD, Ferguson TB Jr, Cain ME. Abolishing ectopic atrial tachycardia with surgery if drug fails. Cardiology Board Review. 1994; II(No. 4).
- Cain ME. Management of sustained ventricular arrhythmias - Editorial Overview. Coronary Artery Disease. 1994; 8.
- Fisher JD, Cain ME, Ferdinand KC, Fisch, C, Kennedy JW, Kutalek SP, Lambert CR, Nissen SE, Okike ON, Ryan T, Saksena SV, Schelbert HR, Schroeder JS, Williams DO. American College of Cardiology Cardiovascular Technology Assessment Committee Position Statement: Catheter ablation for cardiac arrhythmias: Clinical applications, personnel and facilities. J Am Coll Cardiol. 1994; 24.
- Prager NA, Cox JL, Lindsay BD, Ferguson TB, Osborn JL, Cain ME. Long-term effectiveness of surgical treatment of ectopic atrial tachycardia. J Am Coll Cardiol. 1993; 22(1).
- Cain ME. Pathophysiologic basis of the altered frequency components in signal-averaged ECGs. Heart. 1993.
- Hood MA, Pogwizd SM, Peirick J, Cain ME. Contribution of myocardium responsible for ventricular tachycardia to abnormalities detected by analysis of signal-averaged ECGs. Circulation. 1992; 86(6).
- Pogwizd SM, Hoyt RH, Saffitz JE, Corr PB, Cox JL, Cain ME. Reentrant and focal mechanisms underlying ventricular tachycardia in the human heart. Circulation. 1992; 86(6).
- Cain ME, Ambos HD, Lindsay BD, Arthur RM. Contributions of frequency analysis to the identification of the spectral, temporal, and spatial features in signal-averaged electrocardiograms that distinguish patients prone to sustained ventricular arrhythmias. Prog Cardiovasc Dis. 1992; 35(3).
- Lindsay BD, Eichling JO, Ambos HD, Cain ME. Radiation exposure to patients and medical personnel during radiofrequency catheter ablation for supraventricular tachycardia. Am J Cardiol. 1992; 70(2).
- Cain ME, Luke RA, Lindsay BD. Diagnosis and localization of accessory pathways. Pacing Clin Electrophysiol. 1992; 15(5).
- Lindsay BD, Osborn JL, Schechtman KB, Kenzora JL, Ambos HD, Cain ME. Prospective detection of vulnerability to sustained ventricular tachycardia in patients awaiting cardiac transplantation. Am J Cardiol. 1992; 69(6).
- Cox JL, Boineau JP, Schuessler RB, Ferguson TB, Cain ME, Lindsay BD, Corr PB, Kater KM, Lappas DG. Successful surgical treatment of atrial fibrillation. Review and clinical update. JAMA. 1991; 266(14).
- Branyas NA, Cassidy DM, Cain ME. Periodicity of global ventricular activation of sinus beats in patients with coronary artery disease and sustained ventricular tachycardia. Am J Cardiol. 1991; 68(9).
- Cox JL, Boineau JP, Schuessler RB, Ferguson TB, Cain ME, Lindsay BD, Corr PB, Kater KM, Lappas DG. Operations for atrial fibrillation. Clin Cardiol. 1991; 14(10).
- Cain ME, Ambos HD, Markham J, Lindsay BD, Arthur RM. Diagnostic implications of spectral and temporal analysis of the entire cardiac cycle in patients with ventricular tachycardia. Circulation. 1991; 83(5).
- Cox JL, Schuessler RB, D'Agostino HJ, Stone CM, Chang BC, Cain ME, Corr PB, Boineau JP. The surgical treatment of atrial fibrillation. III. Development of a definitive surgical procedure. J Thorac Cardiovasc Surg. 1991; 101(4).
- Cox JL, Canavan TE, Schuessler RB, Cain ME, Lindsay BD, Stone C, Smith PK, Corr PB, Boineau JP. The surgical treatment of atrial fibrillation. II. Intraoperative electrophysiologic mapping and description of the electrophysiologic basis of atrial flutter and atrial fibrillation. J Thorac Cardiovasc Surg. 1991; 101(3).
- Onufer JR, Cain ME. Impact of mapping and ablation of ventricular tachycardia on management strategies for the 1990s. J Cardiovasc Electrophysiology. 1991; 2.
- Arthur RM, Ambos HD, Cain ME. Construction of body surface isoharmonic maps from Frank XYZ leads. Computers in Cardiology. 1991.
- Cain ME. High-resolution electrocardiography-Editorial Overview. Coronary Artery Disease. 1991; 2.
- Branyas NA, Cain ME, Cox JL, Cassidy DM. Transmural ventricular activation during consecutive cycles of sustained ventricular tachycardia associated with coronary artery disease. Am J Cardiol. 1990; 65(13).
- Cox JL, Ferguson TB, Lindsay BD, Cain ME. Perinodal cryosurgery for atrioventricular node reentry tachycardia in 23 patients. J Thorac Cardiovasc Surg. 1990; 99(3).
- Chang BC, Schuessler RB, Stone CM, Branham BH, Canavan TE, Boineau JP, Cain ME, Corr PB, Cox JL. Computerized activation sequence mapping of the human atrial septum. Ann Thorac Surg. 1990; 49(2).
- Cox JL, Schuessler RB, Cain ME, Corr PB, Stone CM, D'Agostino HJ, Harada A, Chang BC, Smith PK, Boineau JP. Surgery for atrial fibrillation. Semin Thorac Cardiovasc Surg. 1989; 1(1).
- Cassidy DM, Cain ME. Surface electrocardiography: can arrhythmia circuits be localized? J Am Coll Cardiol. 1989; 13(4).
- Boineau JP, Schuessler RB, Canavan TE, Corr PB, Cain ME, Cox JL. The human atrial pacemaker complex. J Electrocardiol. 1989; 22 Su.
- Lindsay BD, Ambos HD, Schechtman KB, Cain ME. Improved differentiation of patients with and without ventricular tachycardia by frequency analysis of multiple electrocardiographic leads. Am J Cardiol. 1988; 62(9).
- Canavan TE, Schuessler RB, Boineau JP, Corr PB, Cain ME, Cox JL. Computerized global electrophysiological mapping of the atrium in patients with Wolff-Parkinson-White syndrome. Ann Thorac Surg. 1988; 46(2).
- Boineau JP, Canavan TE, Schuessler RB, Cain ME, Corr PB, Cox JL. Demonstration of a widely distributed atrial pacemaker complex in the human heart. Circulation. 1988; 77(6).
- Branyas NA, Lindsay BD, Cain ME. Nonpharmacologic management of patients with supraventricular tachyarrhythmias. Prog Clin Biol Res. 1988; 275.
- Ambos HD, Markham J, Moore SM, Cain ME. Spectral analysis of the entire cardiac cycle from signal-averaged ECGs for the detection of patients prone to ventricular tachycardia. Computers in Cardiology. 1988.
- Crossen KJ, Lindsay BD, Cain ME. Reliability of retrograde atrial activation patterns during ventricular pacing for localizing accessory pathways. J Am Coll Cardiol. 1987; 9(6).
- Lindsay BD, Crossen KJ, Cain ME. Concordance of distinguishing electrocardiographic features during sinus rhythm with the location of accessory pathways in the Wolff-Parkinson-White syndrome. Am J Cardiol. 1987; 59(12).
- Cain ME, Ambos HD. Noninvasive detection of risk for ventricular arrhythmias. Proceedings 40th Annual Conference on Engineering in Medicine and Biology. 1987.
- Cain ME. Electrophysiologic assessment of sinus node function. Circulation. 1987; 75.
- Ambos HD, Markham J, Lindsay BD, Cain ME. Spectral analysis of signal-averaged electrocardiograms from patients with and without sustained ventricular tachycardia. Computers in Cardiology. 1987.
- Kramer JB, Corr PB, Cox JL, Witkowski FX, Cain ME. Simultaneous computer mapping to facilitate intraoperative localization of accessory pathways in patients with Wolff-Parkinson-White syndrome. Am J Cardiol. 1985; 56(10).
- Cox JL, Gallagher JJ, Cain ME. Experience with 118 consecutive patients undergoing operation for the Wolff-Parkinson-White syndrome. J Thorac Cardiovasc Surg. 1985; 90(4).
- Cain ME, Ambos HD, Markham J, Fischer AE, Sobel BE. Quantification of differences in frequency content of signal-averaged electrocardiograms in patients with compared to those without sustained ventricular tachycardia. Am J Cardiol. 1985; 55(13 Pt).
- Marchlinski FE, Cain ME, Falcone RA, Corky RF, Spear JF, Josephson ME. Effects of infarction, procainamide, coupling interval, and cycle length on refractoriness of extrastimuli. Am J Physiol. 1985; 248(5 Pt).
- Cain ME, Ambos HD. Detection of patients with malignant ventricular arrhythmia by frequency analysis of signal-averaged electrocardiograms. Computerized Interpretation of the Electrocardiogram-Proceedings of the 1984 Engineering Foundation Conference. 1985.
- Cain ME, Ambos HD, Witkowski FX, Sobel BE. Fast-Fourier transform analysis of signal-averaged electrocardiograms for identification of patients prone to sustained ventricular tachycardia. Circulation. 1984; 69(4).
- Ambos HD, Markham J, Cain ME. Use of fast Fourier transform analysis to detect patients prone to sustained ventricular arrhythmias. Computers in Cardiology. 1984.
- Cain ME, Martin TC, Marchlinski FE, Josephson ME. Changes in ventricular refractoriness after an extrastimulus: effects of prematurity, cycle length and procainamide. Am J Cardiol. 1983; 52(8).
- Cain ME, Martin TC, Sobel BE. Beta-adrenergic blocking agents and calcium antagonists in combination: safety and clinical implications. J Cardiovasc Med. 1983.
- Roy D, Waxman HL, Buxton AE, Marchlinski FE, Cain ME, Gardner MJ, Josephson ME. Termination of ventricular tachycardia: role of tachycardia cycle length. Am J Cardiol. 1982; 50(6).
- Gardner MJ, Waxman HL, Buxton AE, Cain ME, Josephson ME. Termination of ventricular tachycardia. Evaluation of a new pacing method. Am J Cardiol. 1982; 50(6).
- Josephson ME, Waxman HL, Cain ME, Gardner MJ, Buxton AE. Ventricular activation during ventricular endocardial pacing. II. Role of pace-mapping to localize origin of ventricular tachycardia. Am J Cardiol. 1982; 50(1).
- Waxman HL, Cain ME, Greenspan AM, Josephson ME. Termination of ventricular tachycardia with ventricular stimulation: salutary effect of increased current strength. Circulation. 1982; 65(4).
- Corr PB, Snyder DW, Cain ME, Crafford WA, Gross RW, Sobel BE. Electrophysiological effects of amphiphiles on canine purkinje fibers. Implications for dysrhythmia secondary to ischemia. Circ Res. 1981; 49(2).
- Josephson ME, Horowitz LN, Waxman HL, Cain ME, Spielman SR, Greenspan AM, Marchlinski FE, Ezri MD. Sustained ventricular tachycardia: role of the 12-lead electrocardiogram in localizing site of origin. Circulation. 1981; 64(2).
- Josephson ME, Waxman HL, Cain ME, Gardner MJ, Buxton AE, Ezri MD, Marchlinski FE. Role of the 12-lead electrocardiogram in identifying site of origin of ventricular rhythms. Computerized Interpretation of the Electrocardiogram-Proceedings of the 1981 Engineering Foundation Conference. 1981.
Books and Book Chapters:
- Smith TW, Cain ME, Breithardt G, Kirchof P. Pharmacology of Sudden Death. 2006.
- Smith TW, Cain ME. Class III Antiarrhythmic Drugs: Amiodarone, Ibutilide, and Sotalol. 2004.
- Narayan S, Cain ME. Non-invasive techniques for assessing arrhythmia risk: T-wave alternans, signal-averaged ECGs and heart rate variability. 2003.
- Narayan SM, Cain ME. Identifying patients at risk for sudden cardiac death: Is low ejection fraction alone enough or do we need additional testing?. 2003.
- Cain ME, Smith JM, Cox JL. Surgery for atrial fibrillation: the next step in the development of a nonpharmacologic cure. 1998.
- Cain ME, Ambos HD, Arthur RM. Signal-averaged electrocardiography. Methods of analysis and clinical impact. 1997.
- Botteron GW, Cain ME. Lessons from mapping atrial fibrillation in humans: implications for ablation. 1997.
- Cain ME. Atrioventricular Nodal Reentrant Tachycardia. 1996.
- Cain ME. Palpitations. 1996.
- Cain ME, Ambos HD, Kavesh NG, Arthur RM. Signal-Averaged Electrocardiography. 1996.
- Sobel BE, Eisenberg PR, Cain ME. Medical Management of Heart Disease. 1996.
- Gamache MC, Cain ME. Cardiac arrhythmias. 1994.
- Lappas DG, Hogue CW, Cain ME, Cox JL. Anesthesia for electrophysiological procedures. 1993.
- Cain ME, Lindsay BD, Ambox HD. Value of frequency domain analysis in identifying patients with ventricular tachyarrhythmias. 1992.
- Cain ME, Ambos HD, Arthur RM, Lindsay BD. Signal-averaged electrocardiography. Methods of analysis and clinical impact. 1991; I.
- Lindsay BD, Branyas NA, Cain ME. The pre-excitations syndrome. 1990.
- Cain ME, Lindsay BD. Pre-excitations syndromes: diagnostic and management strategies. 1990.
- Cain ME, Lindsay BD. The preoperative electrophysiologic study. 1990.
- Cain ME, Lindsay BD, Arthur RM, Markham J, Ambos HD. Noninvasive detection of patients prone to life-threatening ventricular arrhythmias by frequency analysis of electrocardiographic signals. 1990.
- Boineau JP, Schuessler RB, Cain ME, Corr PB, Cox JL. Activation mapping during normal atrial rhythms and atrial flutter. 1990.
- Cain ME. Newer antiarrhythmic agents and their role in ventricular arrhythmias. An overview of management strategies for the 1990‘s. 1990.
- Cain ME. Indications for the treatment of ventricular arrhythmias. 1988.
- Cain ME, Ambos HD, Lindsay BDE. Frequenzanalyse des signalgemittelten Elektrokardiogramms zur Erkennung von Patienten mit anhaltenden ventrikularen Tachykardien. 1987.
- Cain ME, Ambos HD, Lindsay BD. Fast-Fourier transform analysis of the signal-averaged electrocardiogram in the management of patients with or prone to ventricular tachycardia or fibrillation. 1987.
- Boerner JA, Cain ME. Cardiac Arrhythmias. 1987.
- Cain ME, Cox JL. Surgical Treatment of Supraventricular Arrhythmias. 1987.
- Corr PB, Cain ME. Electrophysiology. 1987.
- Cox JL, Cain ME. Surgery for Pre-excitation Syndromes. 1986.
- Crossen KJ, Cain ME. Assessment and Management of Sinus Node Dysfunction. 1986; 55.
- Lindsay BD, Cain ME. Cardiac Arrhythmia. 1986.
- Cain ME, Rosenblum A. Cardiac dysrhythmias. 1983.
- Cain ME, Josephson ME. Quinidine. 1982.
- Cain ME, Josephson ME. Procainamide. 1982.
- Cain ME, Josephson ME. Disopyramide. 1982.
- Cain ME, Horowitz LN, Harken AH, Josephson ME. Surgical management of ventricular dysrhythmias. 1982.
- Cain ME, Josephson ME. Ventricular dysrhythmias: recent advances in assessment and management. 1982.
Evaluative Studies and Case Reports:
- Canavan TE, Schuessler RB, Cain ME, Lindsay BD, Boineau JP, Corr PB, Cox JL. Computerized global electrophysiological mapping of the atrium in a patient with multiple supraventricular tachyarrhythmias. Ann Thorac Surg. 1988; 46(2).
Professional Memberships:
- American Clinical and Climatological Association (Member) (2012–present)
- Associated Medical Schools of New York (2006–present)
- American Association of Medical Colleges Council of Deans (2006–present)
- Clinical Research Forum (2006–present)
- Association of University Cardiologists (1997–present)
- Central Society for Clinical Research (1995–present)
- Association of Professors of Cardiology (1994–2006)
- International Society for Computerized Electrocardiography (1987–present)
- Heart Rhythm Society; Formerly North American Society of Pacing and Electrophysiology (1985–present)
- American Heart Association, Council on Basic Science (1984–present)
- American Heart Association, Council of Clinical Cardiology (1984–present)
- American College of Cardiology (1984–present)
- Cardiac Electrophysiology Society (1980–present)
- American Federation Clinical Research (1980–present)
- American Medical Association (1980–present)
- American Heart Association (1977–present)
Presentations:
- 22nd World Congress on Heart Disease, International Academy of Cardiology (2017)
- 4th John P. Boineau Memorial Lecture, Washington University in St. Louis, Cardiovascular Division, Department of Medicine, Division of Cardiothoracic Surgery, Department of Surgery (2016)
- "Prevention of Sudden Cardiac Death: Challenges and Opportunities" 21st World Congress on Heart Disease, International Academy of Cardiology, Electrophysiology: Sudden Death, Arrhthmias and Device Therapy (2016)
- 2016 Heart Rhythm Society 2016 Annual Scientific Sessions, Heart Rhythm Society (2016)
- 21st World Congress on Heart Disease, International Academy of Cardiology (2016)
- "The 2014 AF Guidelines: What‘s New?" 20th World Congress on Heart Disease, International Academy of Cardiology, Arrhythmia, Electrophysioogy and Stroke Prevention (2015)
- "Macro- and Micro-Level Connections for Collaboration, Teamwork, and Productivity" Tradeline Facility Strategies for Academic Medicine and Allied Health, Tradeline (2014)
- "How Is EP Best Practiced? Today's Realities and Tomorrow's Prospects" Heart Rhythm 2014 35th Annual Scientific Sessions, Heart Rhythm Society (2014)
- 19th World Congress on Heart Disease, International Academy of Cardiology (2014)
- "Sudden Cardiac Death/Advances in Implantable Rhythm Device Therapy" 18th World Congress in Heart Disease, International Academy of Cardiology (2013)
- "Navigating the Perfect Storm Facing Academic Cardiology" Association of Professors of Cardiology, Association of Professors of Cardiology (2013)
- "New Insights into Identification of Patients at Risk for Sudden Cardiac Death" 17th World Congress on Heart Disease, International Academy of Cardiology, Sudden Death and Novel Approaches to Arrhythmia Management (2012)
- 15th World Congress on Heart Disease, International Academy of Cardiology (2010)
- Heart Rhythm 2010, Heart Rhythm Society (2010)
- Heart Rhythm 2009, Heart Rhythm Society (2009)
- 11th International Workshop on Cardiac Arrhythmias (2009)
- American Heart Association Scientific Sessions 2009, American Heart Association (2009)
- 14th World Congress on Heart Disease, International Academy of Cardiology (2008)
- Heart Rhythm 2008, Heart Rhythm Society (2008)
- "How to Become a Clinical Investigator" , American College of Cardiology (2008)
- American Heart Association Scientific Sessions, American Heart Association (2007)
- 13th World Congress on Heart Disease, International Academy of Cardiology (2007)
- 10th International Workshop on Cardiac Arrhythmias (2007)
- Europace 2007 (2007)
- "How to Become a Clinical Investigator" , American College of Cardiology (2007)
- American Heart Association Scientific Sessions, American Heart Association (2006)
- 15th World Congress in Cardiac Electrophysiology and Cardiac Techniques (2006)
- XII International Symposium on Pacing (2006)
- Heart Rhythm Society 27th Annual Scientific Session, Heart Rhythm Society (2006)
- Heart Rhythm Society 26th Annual Scientific Session, Heart Rhythm Society (2005)
- Europace 2005 (2005)
- 12th World Congress on Heart Disease, International Academy of Cardiology (2005)
- 9th International Workshop on Cardiac Arrhythmias (2005)
- American Heart Association Scientific Sessions 2005, American Heart Association (2005)
- American College of Cardiology 54th Annual Scientific Sessions, American College of Cardiology (2005)
- 14th World Congress in Cardiac Electrophysiology and Cardiac Techniques, Cardiostim 2004 (2004)
- European Society of Cardiology (2004)
- XI International Symposium on Pacing (2004)
- Heart Rhythm Society (formerly NASPE) 25th Annual Scientific Session, Heart Rhythm Society (formerly NASPE) (2004)
- "Major Topics in Cardiology Today" 37th Annual New York Cardiovascular Symposium (2004)
- American College of Cardiology 52nd Annual Scientific Sessions, American College of Cardiology (2003)
- 12th World Congress on Cardiac Pacing and Electrophysiology (2003)
- Eighth International Workshop on Cardiac Arrhythmias (2003)
- Europace 2003 (2003)
- North American Society of Pacing and Electrophysiology 24th Annual Scientific Session, North American Society of Pacing and Electrophysiology (2003)
- Joint US-Russia Symposium on New Development in Cardiac Arrhythmias, National Heart, Lung and Blood Intitute and Russian Cardiology Research Center (2003)
- "How to Become a Cardiovascular Investigator" , American College of Cardiology (2003)
- North American Society of Pacing and Electrophysiology 23rd Annual Scientific Session, North American Society of Pacing and Electrophysiology (2002)
- American College of Cardiology 51st Annual Scientific Sessions, American College of Cardiology (2002)
- EP '02 Spotlight Sunday Electrophysiology Symposium (2002)
- 66th Annual Scientific Meeting of the Japanese Circulation Society, Japanese Circulation Society (2002)
- Seventh Asian-Pacific Society of Pacing and Electrophysiology Scientific Sessions (2001)
- North American Society of Pacing and Electrophysiology 22nd Annual Scientific Session, North American Society of Pacing and Electrophysiology (2001)
- North American Society of Pacing and Electrophysiology 21st Annual Scientific Session, North American Society of Pacing and Electrophysiology (2000)
- American College of Cardiology 50th Annual Scientific Sessions, American College of Cardiology (2000)
- Seventh World Congress on Heart Failure, International Academy of Cardiology (2000)
- "Cardiac Electrophysiology Board Review Course" , North American Society of Pacing and Electrophysiology and American College of Cardiology (2000)
- American College of Cardiology 49th Annual Scientific Sessions, American College of Cardiology (1999)
- North American Society of Pacing and Electrophysiology 20th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1999)
- "Cardiac Electrophysiology Board Review Course" , North American Society of Pacing and Electrophysiology and American College of Cardiology (1999)
- North American Society of Pacing and Electrophysiology 19th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1998)
- American College of Cardiology Cardiovascular Board Review, American College of Cardiology (1998)
- Fifth International Symposium on High-Resolution ECG and Late Potentials and Noninvasive Electrophysiology, 11th International Congress - Cardiostim 98 (1998)
- "Cardiac Electrophysiology Board Review Course" , North American Society of Pacing and Electrophysiology and American College of Cardiology (1998)
- American College of Cardiology 46th Annual Scientific Sessions, American College of Cardiology (1997)
- North American Society of Pacing and Electrophysiology 18th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1997)
- North American Society of Pacing and Electrophysiology 17th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1996)
- American College of Cardiology 45th Annual Scientific Sessions, American College of Cardiology (1996)
- Symposium on Nonpharmacological Management of Atrial Fibrillation (1996)
- CME in the Orient, Thai Physicians Association of America/Washington University School of Medicine (1996)
- 29th Annual New York Cardiovascular Symposium (1996)
- "Cardiac Electrphysiology Board Review Course" , North American Society of Pacing and Electrophysiology and American College of Cardiology (1996)
- American Heart Association 68th Annual Scientific Sessions, American Heart Association (1995)
- 25th National Meeting, Spanish Society of Cardiology (1995)
- 42nd Scientific Sessions, Japanese College of Cardiology (1994)
- American Heart Association 67th Annual Scientific Sessions, American Heart Association (1994)
- North American Society of Pacing and Electrophysiology 15th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1994)
- "Clinical Electrophysiology Board Review Course" , American College of Cardiology (1994)
- North American Society of Pacing and Electrophysiology 14th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1993)
- American College of Cardiology 42nd Annual Scientific Sessions, American College of Cardiology (1993)
- American Heart Association 66th Annual Scientific Sessions, American Heart Association (1993)
- 3rd Annual Japanese Symposium on High Resolution Electrocardiography (1993)
- 14th Hellenic Armed Forces Medical Conference (1992)
- First International Symposium on Cardiac Arrhythmias; 8th International Congress-Cardiostim 92 (1992)
- American College of Cardiology 41st Annual Scientific Sessions, American College of Cardiology (1992)
- American College of Cardiology Clinical Electrophysiology Board Review Course, American College of Cardiology (1992)
- American Heart Association 65th Annual Scientific Sessions, American Heart Association (1992)
- North American Society of Pacing and Electrophysiology 13th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1992)
- North American Society of Pacing and Electrophysiology IX World Symposium, North American Society of Pacing and Electrophysiology (1991)
- American College of Cardiology 40th Annual Scientific Sessions, American College of Cardiology (1991)
- 5th Puerto Rico Congress of Cardiology (1991)
- American College of Cardiology Heart House Learning Center Program, American College of Cardiology (1991)
- Mapfre Medicina Foundatino Symposium (1991)
- International Symposium on Cardiac Pacing and Electrophysiology (1991)
- American College of Cardiology Heart House Learning Center Program, American College of Cardiology (1990)
- American College of Cardiology 39th Annual Scientific Sessions, American College of Cardiology (1990)
- Joint USA-USSR Symposium on Coronary Artery Disease, NIH National Heart, Lung, Blood Institute and Cardiology Research Institute of the USSR (1990)
- American College of Cardiology 38th Annual Scientific Sessions, American College of Cardiology (1989)
- American Heart Association 62nd Annual Scientific Sessions, American Heart Association (1989)
- North American Society of Pacing and Electrophysiology 10th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1989)
- "Practical Application of Electrophysiologic Studies for Diagnosis and Management of Arrhythmias" Heart House Learning Center Program, American College of Cardiology (1989)
- North American Society of Pacing and Electrophysiology 9th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1988)
- American Heart Association 61st Annual Scientific Sessions, American Heart Association (1988)
- "Practical Application of Electrophysiologic Studies for Diagnosis and Management of Arrhythmias" Heart House Learning Center Program, American College of Cardiology (1988)
- North American Society of Pacing and Electrophysiology 8th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1987)
- American Heart Association 60th Annual Scientific Sessions, American Heart Association (1987)
- 20 Years of Programmed Stimulation of the Heart, Where to Go from Here (1987)
- International College of Angiology 29th Annual Meeting (1987)
- "Practical Application of Electrophysiologic Studies for Diagnosis and Management of Arrhythmias" Heart House Learning Center Program, American College of Cardiology (1987)
- International Workshop on the Patient at Risk of Sustained Ventricular Tachyarrhythmias (1986)
- International College of Angiology 28th Annual Meeting (1986)
- "Practical Application of Electrophysiologic Studies for Diagnosis and Management of Arrhythmias" Heart House Learning Center Program, American College of Cardiology (1986)
- North American Society of Pacing and Electrophysiology 6th Annual Scientific Session, North American Society of Pacing and Electrophysiology (1985)
- "Practical Application of Electrophysiologic Studies for Diagnosis and Management of Arrhythmias" Heart House Learning Center Program, American College of Cardiology (1985)
- "Practical Application of Electrophysiologic Studies for Diagnosis and Management of Arrhythmias" Heart House Learning Center Program, American College of Cariodology (1984)
Service Activities:
- HEALTHeLINK Board of Directors; Secretary (2017–present)
- HEALTHeLINK Executive Committee; Member (2014–present)
- Associated Medical Schools of New York; Vice-Chair (2011–present)
- HEALTHeLINK; Board Member (2011–present)
- Women and Children‘s Hospital of Buffalo Advisory Council; Buffalo, NY; Member (2009–2017)
- Women and Children‘s Hospital of Buffalo, Professional Steering Planning Committee‘s Inpatient Subcommittee; Buffalo, NY; Member (2009–2013)
- The Palliative Care Institute Board of Directors; Buffalo, NY; Member (2009–2012)
- Women and Children‘s Hospital of Buffalo, Professional Steering Planning Committee‘s Transition Care Subcommittee; Buffalo, NY; Member (2009–2010)
- University at Buffalo School of Medicine and Biomedical Sciences Department of Gynecology and Obstetrics Diane and Morton Stenchever Memorial Lecturer; Guest Lecturer (2009)
- Circulation: Arrhythmias and Electrophysiology; Guest Editor (2008–present)
- Great Lakes Health of WNY, Professional Steering Committee; Buffalo, NY; Member (2008–present)
- Great Lakes Health System of WNY Board of Directors; Buffalo, NY; Member (2008–present)
- Circulation; Guest Editor (2007–2016)
- CUBRC Board of Directors; Buffalo, NY; Member (2007–2013)
- The Sarnoff Endowment for Cardiovascular Research Board of Directors; Immediate Past Chair (2007–2008)
- The Sarnoff Endowment for Cardiovascular Research Governance Committee; Chair (2007–2008)
- University at Buffalo School of Medicine and Biomedical Sciences Distinguished Lecturer, Alpha Omega Alpha; Guest Lecturer (2007)
- The Sarnoff Endowment for Cardiovascular Research Governance Committee; Member (2007–present)
- Heart Rhythm Society (NASPE) Publications Committee; Chair (2006–2010)
- The Sarnoff Endowment for Cardiovascular Research Board of Directors; Chair (2006–2007)
- Associated Medical Schools of New York; Board Member (2006–present)
- ECMC Lifeline Foundation Board of Directors; Eric County Medical Center Buffalo, NY; Member (2006–present)
- The Sarnoff Endowment for Cardiovascular Research Board of Directors; Member (2006–present)
- Washington University School of Medicine, Radiation Safety Committee; St. Louis, MO; Member (2005–2006)
- Heart Rhythm; Editorial Board Member (2004–2010)
- Nature Clinical Practice Cardiovascular Medicine Advisory Board; Member (2004–2010)
- Heart Rhythm Society (NASPE) International Coalition of Pacing and Electrophysiology Organization; Co-Chair (2004–2007)
- Association of Subspecialty Professors Advocacy Committee; Member (2004–2006)
- The Sarnoff Endowment for Cardiovascular Research Strategic Planning Committee; Co-Chair (2004–2006)
- Heart Rhythm Society, Board of Trustees; Past President (2004–2005)
- The Sarnoff Endowment for Cardiovascular Research, Scientific Board; Immediate Past Chair (2004–2005)
- Association of Professors of Cardiology; Past President (2004)
- Heart Rhythm Society (NASPE) Board of Trustees; President (2003–2004)
- The Sarnoff Endowment for Cardiovascular Research Scientific Board; Chair (2003–2004)
- Association of Professors of Cardiology; President (2003)
- FDA, Medical Devices Advisory Committee Circulatory System Devices Panel; Consultant (2003–present)
- Journal of American College of Cardiology; Editorial Board Member (2002–2006)
- The Sarnoff Endowment for Cardiovascular Research, Scientific Board; and Program Director; Vice-Chair (2002–2003)
- Association of Professors of Cardiology (President elect); Other (2002)
- Olympic Winter Games, Salt Lake 2002 Olympic Torch Relay; Member (2002)
- Journal of Interventional Cardiac Electrophysiology; Editorial Board Member (2001–2005)
- Heart Rhythm Soceity (NASPE), Board of Trustees (President elect); Heart Rhythm Society; Other (2001–2003)
- American College of Cardiology, Cardiac Arrhythmia Section, Annual Scientific Session Program Committee; Chair (2001–2002)
- Heart Rhythm Society (NASPE) 23rd Annual Scientific Sessions (Program Chair); Chair (2001–2002)
- Heart Rhythm Society (NASPE) Board of Trustees; First Vice President (2001–2002)
- ABIM Committee for Clinical Cardiac Electrophysiology (CCEP); American Board of Internal Medicine; Member (2000–2006)
- Washington University School of Medicine, Faculty Practice Plan Board; St. Louis, MO; Member (2000–2003)
- Association of Professors of Cardiology; Secretary/Treasurer (2000–2001)
- Heart Rhythm Society (NASPE) 22nd Annual Scientific Sessions (Abstract Chair); Chair (2000–2001)
- Heart Rhythm Society (NASPE), Board of Trustees (Second VP); Heart Rhythm Society; Vice President (2000–2001)
- The Sarnoff Endowment for Cardiovascular Research Scientific Board; Member (1999–2006)
- Heart Rhythm Society (NASPE) Executive Committee; Member (1999–2005)
- Heart Rhythm Society (NASPE) Annual Scientific Sessions Program Committee; Member (1999–2004)
- American College of Cardiology, Annual Scientific Sessions Program Committee; Member (1999–2002)
- Heart Rhythm Society (NASPE), Board of Trustees; Now Heart Rhythm Society; Secretary (1999–2000)
- Heart Rhythm Society Board of Trustees; formerly North American Society of Pacing and Electrophysiology; Member (1998–2006)
- ABIM Clinical Cardiac Electrophysiology Self-Evaluation Process (SEP); American Board of Internal Medicine; Member (1998–1999)
- Journal of Cardiovascular Electrophysiology; Editorial Board Member (1998–present)
- Heart Rhythm Society (NASPE) Committee on Health Policy; Member (1997–2000)
- Washington University School of Medicine, Faculty Practice Plan Strategic Planning Committee; School of Medicine St. Louis, MO; Member (1997–2000)
- Barnes-Jewish Hospital/Washington University, Medical Cost Management Cardiovascular Diseases Design Team; School of Medicine St. Louis, MO; Chair (1997–1999)
- Association of University Cardiologists; Member (1997–present)
- Barnes-Jewish Hospital/Washington University, Heart Services Clinical Service Line Steering Committee; Barnes-Jewish Hospital/Washington University School of Medicine Joint Office of Strategic Planning St. Louis, MO; Member (1996–2006)
- Barnes-Jewish Hospital/Washington University, Ambulatory Operations Design Team, Ambulatory Care Center; School of Medicine St. Louis, MO; Co-Chair (1996–2000)
- Barnes-Jewish Hospital/Washington University, Clinical Service Delivery Design Team, Heart Services Clinical Service Line; School of Medicine Joint Office of Strategic Planning St. Louis, MO; Co-Chair (1996–2000)
- American Heart Association, Board of Directors (Missouri Affiliate); Member (1996–1998)
- American Heart Association, Board of Directors (St. Louis Chapter); President (1996–1998)
- Clinical Cardiac Electrophysiology Training Programs, Residency Review Committee for Internal Medicine; Reviewer (1996)
- Heart Rhythm Society (NASPE) Long Range Planning Committee; Member (1995–2001)
- Heart Rhythm Society (NASPE) and American College of Cardiology Board Review Course in Clinical Electrophysiology and Pacing; Co-Director (1995–2000)
- Heart Rhythm Society (NASPE) Publications Committee; Chair (1995–1998)
- Central Society for Clinical Research; Member (1995–present)
- American College of Cardiology, Board of Governors Steering Committee; Member (1994–1995)
- American College of Cardiology, Board of Governors Working Group on Academic Medical Centers; Member (1994–1995)
- Heart Rhythm Society (NASPE) Government Relations Physicians Workforce, Clinical Resources and Education Committee; Member (1994–1995)
- Coronary Artery Disease/Review-in-Depth Management of Sustained Ventricular Arrhythmias; 1994; 8:649-685; Editor (1994)
- Association of Professors of Cardiology; Member (1993–2006)
- Journal American College of Cardiology; Editorial Board Member (1993–1997)
- Washington University School of Medicine, Promotions Committee, Department of Medicine; Member (1993–1997)
- American College of Cardiology, Cardiovascular Technology Assessment Committee; Member (1993–1994)
- American Heart Association, Board of Directors (St. Louis Chapter); Vice President (1992–1996)
- American College of Cardiology Board of Directors (Missouri Chapter); President (1992–1995)
- American College of Cardiology Board of Directors (Missouri) College Governor; Other (1991–1995)
- American College of Cardiology Board of Directors (Missouri) College Governor-Elect; Other (1991)
- Coronary Artery Disease/Review-in-Depth High Resolution Electrocardiography; 1991; 2:1-41; Editor (1991)
- American Heart Association, Board of Directors (St. Louis Chapter); Assistant Secretary (1990–1992)
- American Heart Association, Committee on Electrocardiography and Electrophysiology, Council on Clinical Cardiology; Member (1988–1990)
- American Heart Association, Task Force Committee on Standards for Analysis of Ventricular Late Potentials Present Using High Resolution Electrocardiog; American Heart Association American College of Cardiology European Society of Cardiology; Member (1988)
- NIH Experimental Cardiovascular Sciences Research Review Committee Special Study Section; National Heart, Lung, Blood Institute Bethesda, MD; Member (1987)
- American Journal of Cardiology; Editorial Board Member (1987–present)
- American Heart Association, Board of Directors St. Louis Chapter; Member (1986–2004)
- Heart Rhythm Society (NASPE) Publications Committee; Member (1986–2000)
- The Video Journal of Cardiology; Editorial Board Member (1985–1997)
- Circulation; Associate Editor (1983–1988)