Michael Buck PhD

Michael Buck

Michael Buck
PhD

Professor and Director Genetics, Genomics and Bioinformatics

Department of Biochemistry

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Contact Information
Jacobs School of Medicine and Biomedical Sciences
Office 5148
955 Main Street
Buffalo, NY 14203
Buffalo, New York 14203
Phone: (716) 881-7569
Fax: NA
mjbuck@buffalo.edu



Professional Summary:

Dr. Buck’s research is focused on uncovering how epigenetics and the microbiome regulate cellular events. Dr. Buck’s laboratory uses multiple model systems to uncover fundamental biological principles which are subsequently translated to the study of human disease.

Instructions controlling cellular functions are contained within DNA that is wrapped and packaged around proteins into chromatin. Chromatin can be modified in response to the environment and these modifications can be passed onto their daughter cells. These modifications act as a cellular memory and are known as epigenetic modifications. Changes in epigenetic modifications are essential players in many disease pathways including: cancer, diabetes, obesity, and autism. Dr. Buck’s research is focused on uncovering how epigenetic changes redirect regulatory proteins and how regulatory proteins read epigenetic modifications.

Our bodies are populated by a diverse and complex population of thousands of microbes, mostly bacteria, but also viruses, fungi and archaea, termed the human microbiota. This co-inhabiting microbial ecosystem has been associated with various human disease including colon cancer, diabetes, periodontal disease, and others. To understand how the microbiota is affecting human health the Buck lab has developed robust and reproducible high-throughput approaches to examine thousands of samples and are currently defining causal relationships between the microbiota and human health.

Education and Training:

  • Fellowship, Gene regulation, chromatin, and genomics, Univeristy of North Carolina at Chapel Hill (2007)
  • PhD, Genetics, North Carolina State University (2003)
  • BS, Biotechnology, Rutgers University, Cum Laude (1997)

Employment:

  • Director, Genetics, Genomics and Bioinformatics, Jacobs School of Medicine and Biomedical Sciences (2021-present)
  • Professor, Biochemistry, Jacobs School of Medicine and Biomedical Sciences (2021-present)
  • Professor, Biomedical Informatics, Jacobs School of Medicine and Biomedical Sciences

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Contact Information

Jacobs School of Medicine and Biomedical Sciences
Office 5148
955 Main Street
Buffalo, NY 14203
Buffalo, New York 14203
Phone: (716) 881-7569
Fax: NA
mjbuck@buffalo.edu