Ferdinand Schweser Ph.D.
Ferdinand Schweser
Ph.D.
Associate Professor, Neurology, Biomedical Engineering, Radiology Technical Director, Center for Biomedical Imaging
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Ageing; Anatomy; Artificial Intelligence; Biomedical Engineering; Biomedical Image Analysis; Biomedical Imaging; Biomedical Imaging; Biomedical Informatics; Biometal Imaging; Biophysical Modeling; Biophysics; Biostatistics; Brain Iron Homeostasis; Brain Research; Clinical Research; Disease Progression Modeling; Image Analysis; Image Processing and Analysis; Imaging Informatics; Inverse Imaging Problems; Magnetic Resonance Imaging (MRI) – High Resolution; Mathematical Modeling; Metabolic Imaging; Molecular Imaging; Molecular Imaging Techniques; Molecular Imaging Techniques; MRI - preclinical; MRI - Ultra-high field; MRI Methodology; Multimodal Imaging Technology; Multiple Sclerosis; Nanoparticles; Neurodegenerative Diseases; Neuroimaging; Neuroimaging Analysis; Neurology; Neuroradiology; Neuroscience; Nuclear Medicine; Preclinical Research; Quantitative Susceptibility Mapping; Quantitative Susceptibility Mapping; Radiological Physics; Radiology; Team Science; Technology; Translational imaging; Translational Research; Traumatic Brain Injury
Professional Summary:
My biomedical imaging research lab fosters translational team-science discovery from mouse to human. My lab is part of the Buffalo Neuroimaging Analysis Center (BNAC). In addition, my lab provides expertise in imaging physics and analysis for the Center for Biomedical Imaging (CBI), a core facility of UB’s Clinical and Translational Science Institute (CTSI), for which I serve as the Technical Director.
My research program targets several interrelated topics in biomedical imaging of neurological disease. The principle thread connecting these topics is the advancement of neuroimaging technology for noninvasive profiling of tissue pathology. The focus of my research program lies in the development and application of novel computational methods to quantify biophysical tissue properties with MRI, primarily those related to tissue iron. Disease progression is associated with disturbed brain iron homeostasis in many neurological diseases, such as multiple sclerosis (MS), providing a strong rationale for the study of brain iron.
I pioneered the development of an MRI method referred to as quantitative susceptibility mapping (QSM). QSM capitalizes on the observation that biological tissues perturb the static magnetic field of the MRI scanner in a predictable way that depends on their magnetizability (or: magnetic susceptibility), which is strongly affected by tissue iron. QSM measures these perturbations and computes the underlying spatial distribution of susceptibility by solving several physics-based inverse mathematical problems, a process to which I have made several groundbreaking contributions.
Alongside my methodological work, a major priority of my research program is the clinical translation of advanced research imaging technology. I pursue this ambition through extensive collaboration with colleagues at the Department of Neurology, the CBI, and external partners.
Education and Training:
- PhD, Medical Physics, Friedrich Schiller University Jena, Summa Cum Laude (2013)
- Certificate, Certified Photonics Professional, Friedrich Schiller University Jena (2008)
- MS, Physics, Friedrich Schiller University Jena, Summa Cum Laude (2008)
- Certificate, Correspondence study of physics and mathematics, University of Kaiserslautern (2003)
Employment:
- Associate Professor, Neurology, University at Buffalo (2021-present)
- Technical Director, Center for Biomedical Imaging, University at Buffalo (2020-present)
- Director of Sequence Development, Buffalo Neuroimaging Analysis Center (2015-present)
- Research Physicist, Buffalo Neuroimaging Analysis Center (2014-present)
- Faculty, Neuroscience Program, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2014-present)
- Graduate Faculty, University at Buffalo (2014-present)
- Assistant Professor, Neurology, University at Buffalo (2014–2021)
- Technical Director of MRI, Center for Biomedical Imaging, University at Buffalo (2015–2020)
- Postdoctoral Associate, Hans Berger Department of Neurology and Experimental Neurology, Jena University Hospital (2013)
- Postdoctoral Associate, Medical Physics, Jena University Hospital, Germany (2013)
- Research Associate, Medical Physics Group, Jena University Hospital Institute of Diagnostic and Interventional Radiology (2013)
- Research Assistant, Medical Physics, Jena University Hospital (2008–2009)
Awards and Honors:
- Editor’s Pick for the Month of July (2021)
- Scialog Fellow for Advancing Bioimaging (2021)
- Top Cited Article 2018-2019 (2020)
- Top Cited Article 2016 (2019)
- Distinguished Service to the Society (2018)
- Editor’s Pick for the Month of March (2018)
- Best Poster (2016)
- Distinguished Service to the Society (2015)
- Grateful Appreciation of Service to the Society (2015)
- Magna Cum Laude Merit Award (2015)
- Distinguished Service to the Society (2014)
- Award for best doctoral dissertation (2014)
- Junior Fellow (2014)
- Varian poster prize (2013)
- Young Investigator Award at 2nd Intl. QSM Workshop (2013)
- ISMRM Summa Cum Laude Merit Award (2013)
- IUPAP Young Scientist Medal in Medical Physics (2013)
- ISMRM 2013 Seed Grant Award (2013)
- Best poster presentation in ISMRM poster-highlights session (2013)
- DGMP Young Investigator Award (2012)
- Invitation to student poster-highlight session (2012)
- ISMRM Magna Cum Laude Merit Award (2012)
- ISMRM Magna Cum Laude Merit Award (2012)
- ISMRM Summa Cum Laude Merit Award (2012)
- ISMRM 1st place poster award (2011)
- Gorter Award (2011)
- Carl Zeiss Foundation doctoral scholarship (2009)
Research Expertise:
- Computational Imaging: biostatistics; machine learning; image processing; image analysis
- Inverse Problems: magnetostatics; source separation
- Magnetic Resonance Imaging (MRI): phase MRI; susceptibility MRI; iron MRI; preclinical imaging; multi-modal imaging
- Neuroimaging: Neurodegenerative disorder; aging
Research Centers:
- Buffalo Neuroimaging Analysis Center
- Clinical and Translational Research Center (CTRC)
- Jacobs Neurological Institute
UB 2020 Strategic Strengths:
- Health and Wellness Across the Lifespan
- Information and Computing Technology
Grants and Sponsored Research:
- April 2021–March 2026
Optimizing Chest Compressions Targeting Gas Exchange and Hemodynamics in a Transitional Cardiac Arrest Model
National Institutes of Health
Role: Co-Investigator
$1,642,389 - July 2021–June 2025
Deep gray matter iron and disease progression in multiple sclerosis.
National Institutes of Health
Role: Principal Investigator
$1,808,000 - February 2020–December 2024
Buffalo Clinical and Translational Research Center
National Institutes of Health
Role: Co-Investigator
$19,101,902 - August 2021–July 2023
Advanced hybrid PET-MRI imaging pipeline at 9.4T
University at Buffalo
Role: Principal Investigator
$100,000 - September 2017–July 2022
The role of acute and chronic neuroinflammation on iron homeostasis and oligodendrocyte viability in the deep gray matter.
The Dana Foundation
Role: Principal Investigator
$200,000 - April 2016–March 2022
Physiological mechanisms of a biomarker of recovery from a concussion
National Institutes of Health
Role: Co-Investigator
$1,723,492 - January 2020–December 2021
Mapping magnetic properties of the aging brain
German Academic Exchange Service
Role: Co-Principal Investigator
$29,700 - July 2019–June 2021
Potential of inhibition of Poly ADP Ribose Polymerase as a therapeutic approach in blast induced cochlear and brain injury
Hearing Health Foundation
Role: Co-Principal Investigator
$29,308 - July 2016–July 2020
The Use of fMRI to Evaluate the Effects of Sound Therapy–Pilot Study
BUNY Buffalo State Research and Creativity Council
Role: Co-Investigator
$7,000 - March 2017–September 2018
Multimodal multiparametric brain mapping for pre-symptomatic diagnosis and treatment development in Krabbe Disease
Role: Principal Investigator
$48,000 - September 2013–September 2014
Disentangling of biophysical contributions to the MR-phase signal in the human brain by analyzing of the multipole field distribution due to the anisotropic magnetic susceptibility of the neuronal network
Friedrich Schiller University Jena
Role: Principal Investigator - May 2014–May 2014
UUP individual Development Award
University At Buffalo
Role: Principal Investigator - April 2013–April 2014
ISMRM Seed Grant
International Society for Magnetic Resonance in Medicine
Role: Principal Investigator - July 2013–September 2013
Research Internship in Science and Engineering (RISE)
German Academic Exchange Service (DAAD)
Role: Principal Investigator - January 2009–December 2011
Doctoral scholarship
Carl Zeiss Foundation
Role: Principal Investigator - July 2010–August 2010
Research Internship in Science and Engineering (RISE)
German Academic Exchange Service (DAAD)
Role: Co-Investigator
Patents:
- Separation of Biophysical Contrast Mechanisms in Biomedical Imaging (2019)
- Method for high accurate extraction of information from at least two-dimensional measurement data of an object, which are superimposed by a signal from external sources (2010)
- SAR hotspot reduction by temporal averaging in parallel transmission MRI (2010)
- Real-time local and global SAR estimation for patient safety and improved scanning performance. (2009)
Journal Articles:
- Marques JP, Meineke J, Milovic C, Bilgic B, Chan KS, Hedouin R, van der Zwaag W, Langkammer C, Schweser F. (2021) QSM reconstruction challenge 2.0: A realistic in silico head phantom for MRI data simulation and evaluation of susceptibility mapping procedures. Magnetic Resonance in Medicine (Jul), 86(1): 526-542. doi:10.1002/mrm.28716
- Dwyer M, Lyman C, Ferrari H, Bergsland N, Fuchs TA, Jakimovski D, Schweser F, Weinstock-Guttmann B, Benedict RHB, Riolo J, Silva D, Zivadinov R. (2021) DeepGRAI (Deep Gray Rating via Artificial Intelligence): Fast, feasible, and clinically relevant thalamic atrophy measurement on clinical quality T2-FLAIR MRI in multiple sclerosis. NeuroImage: Clinical (Mar), 30: 102652. doi:10.1016/j.nicl.2021.102652
- Bilgic B, Langkammer C, Marques J, Meineke J, Milovic C, Schweser F. (2021) QSM reconstruction challenge 2.0: Design and report of results. Magnetic resonance in medicine (Mar), 3(86): 1241-1255.
- Bergsland N, Benedict RHB, Dwyer MG, Fuchs TA, Jakimovski D, Schweser F, Tavazzi E, Weinstock-Guttman B, Zivadinov R. (2021) Thalamic Nuclei Volumes and Their Relationships to Neuroperformance in Multiple Sclerosis: A Cross-Sectional Structural MRI Study. J Magn Reson Imaging (Mar), 53(3): 731-739.
- Pol S, Liang S, Schweser F, Dhanraj R, Schubart A, Preda M, Sveinsson M, Ramasamy DP, Dwyer MG, Weckbecker G, Zivadinov R. (2021) Subcutaneous anti-CD20 antibody treatment delays gray matter atrophy in human myelin oligodendrocyte glycoprotein-induced EAE mice. Exp Neurol (Jan), 335: 113488-113488.
- Schweser F, Hagemeier J, Dwyer MG, Bergsland N, Hametner S, Weinstock-Guttman B, Zivadinov R. (2021) Decreasing brain iron in multiple sclerosis: The difference between concentration and content in iron MRI. Hum Brain Mapp (Jan), 5(42): 1463-1474.
- Zivadinov R, Schweser F, Dwyer MG, Pol S. (2020) Detection of Monocyte/Macrophage and Microglia Activation in the TMEV Model of Chronic Demyelination Using USPIO-Enhanced Ultrahigh-Field Imaging. J Neuroimaging (Nov), 30(6): 769-778.
- Subramanian K, Utriainen D, Ramasamy DP, Sethi SK, Schweser F, Beaver J, Hagemeier J, Weinstock-Guttman B, Rajagovindan R, Zivadinov R, Haacke EM. (2020) Longitudinal Magnetic Resonance Imaging of Cerebral Microbleeds in Multiple Sclerosis Patients. Diagnostics (Nov), 10(11)
- Milovic C, Tejos C, Acosta-Cabronero J, Özbay PS, Schweser F, Marques JP, Irarrazaval P, Bilgic B, Langkammer C. (2020) The 2016 QSM Challenge: Lessons learned and considerations for a future challenge design. Magnetic Resonance in Medicine (Aug), 84(4): 1624-1637.
- Karthikeyan B, Sonkawade SD, Pokharel S, Preda M, Schweser F, Zivadinov R, Kim M, Sharma UC, Sharma U. (2020) Tagged cine magnetic resonance imaging to quantify regional mechanical changes after acute myocardial infarction. Magn Reson Imaging (Jan), 66: 208-218.
- Bergsland N, Tavazzi E, Schweser F, Jakimovski D, Hagemeier J, Dwyer MG, Zivadinov R. (2019) Targeting Iron Dyshomeostasis for Treatment of Neurodegenerative Disorders. CNS Drugs (Nov), 33(11): 1073-1086.
- Deshpande HU, Mellis AM, Lisinski JM, Stein JS, Koffarnus MN, Paluch R, Schweser F, Zivadinov R, LaConte SM, Epstein LH, Bickel WK. (2019) Reinforcer pathology: Common neural substrates for delay discounting and snack purchasing in prediabetics. Brain Cogn (Jun), 132: 80-88.
- Bergsland N, Zivadinov R, Schweser F, Hagemeier J, Lichter D, Guttuso T. (2019) Ventral posterior substantia nigra iron increases over 3 years in Parkinson's disease. Mov Disord (Jun)
- Schweser F, Kyyriäinen J, Preda M, Pitkänen A, Toffolo K, Poulsen A, Donahue K, Levy B, Poulsen D. (2019) Visualization of thalamic calcium influx with quantitative susceptibility mapping as a potential imaging biomarker for repeated mild traumatic brain injury. Neuroimage (Jun), 200: 250-258.
- Soheili-Nezhad S, Sedghi A, Schweser F, Eslami Shahr Babaki A, Jahanshad N, Thompson PM, Beckmann CF, Sprooten E, Toghae M. (2019) Structural and Functional Reorganization of the Brain in Migraine Without Aura. Front Neurol (May), 10: 442-442.
- Pol S, Schweser F, Bertolino N, Preda M, Sveinsson M, Sudyn M, Babek N, Zivadinov R. (2019) Characterization of leptomeningeal inflammation in rodent experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis. Exp Neurol (Apr), 314: 82-90.
- Taege Y, Hagemeier J, Bergsland N, Dwyer MG, Weinstock-Guttman B, Zivadinov R, Schweser F. (2019) Assessment of mesoscopic properties of deep gray matter iron through a model-based simultaneous analysis of magnetic susceptibility and R2* - A pilot study in patients with multiple sclerosis and normal controls. Neuroimage (Feb), 186: 308-320.
- Shi R, Jung JH, Schweser F. (2019) Two-dimensional local Fourier image reconstruction via domain decomposition Fourier continuation method. PLoS One (Jan), 14(1): 0197963-0197963.
- Pol S, Sveinsson M, Sudyn M, Babek N, Siebert D, Bertolino N, Modica CM, Preda M, Schweser F, Zivadinov R. (2019) Teriflunomide's Effect on Glia in Experimental Demyelinating Disease: A Neuroimaging and Histologic Study. J Neuroimaging (Jan), 29(1): 52-61.
- Zivadinov R, Bergsland N, Hagemeier J, Ramasamy DP, Dwyer MG, Schweser F, Kolb C, Weinstock-Guttman B, Hojnacki D, Hojnacki DW. (2019) Cumulative gadodiamide administration leads to brain gadolinium deposition in early MS. Neurology (Jan), 93(6): 611-623.
- Schweser F, Zivadinov R. (2018) Quantitative susceptibility mapping (QSM) with an extended physical model for MRI frequency contrast in the brain: a proof-of-concept of quantitative susceptibility and residual (QUASAR) mapping. NMR Biomed (Dec), 31(12): 3999-3999.
- Zivadinov R, Tavazzi E, Bergsland N, Hagemeier J, Lin F, Dwyer MG, Carl E, Kolb C, Hojnacki D, Ramasamy D, Durfee J, Weinstock-Guttman B, Schweser F, Hojnacki DW. (2018) Brain Iron at Quantitative MRI Is Associated with Disability in Multiple Sclerosis. Radiology (Nov), 289(2): 487-496.
- Bergsland N, Schweser F, Dwyer MG, Weinstock-Guttman B, Benedict RHB, Zivadinov R. (2018) Thalamic white matter in multiple sclerosis: A combined diffusion-tensor imaging and quantitative susceptibility mapping study. Hum Brain Mapp (Oct), 39(10): 4007-4017.
- Zivadinov R, Polak P, Schweser F, Bergsland N, Hagemeier J, Dwyer MG, Ramasamy DP, Baker JG, Leddy JJ, Willer BS. (2018) Multimodal Imaging of Retired Professional Contact Sport Athletes Does Not Provide Evidence of Structural and Functional Brain Damage. J Head Trauma Rehabil (Sep), 33(5): 24-32.
- Zivadinov R, Ramasamy DP, Hagemeier J, Kolb C, Bergsland N, Schweser F, Dwyer MG, Weinstock-Guttman B, Hojnacki D, Hojnacki DW. (2018) Evaluation of Leptomeningeal Contrast Enhancement Using Pre-and Postcontrast Subtraction 3D-FLAIR Imaging in Multiple Sclerosis. AJNR Am J Neuroradiol (Feb).
- Tutino VM, Rajabzadeh-Oghaz H, Chandra AR, Gutierrez LC, Schweser F, Preda M, Chien A, Vakharia K, Ionita C, Siddiqui A, Kolega J, Ionita CN. (2018) 9.4T Magnetic Resonance Imaging of the Mouse Circle of Willis Enables Serial Characterization of Flow-Induced Vascular Remodeling by Computational Fluid Dynamics. Curr Neurovasc Res (Jan), 15(4): 312-325.
- Ziliotto N, Bernardi F, Jakimovski D, Baroni M, Marchetti G, Bergsland N, Ramasamy DP, Weinstock-Guttman B, Schweser F, Zamboni P, Ramanathan M, Zivadinov R. (2018) Hemostasis biomarkers in multiple sclerosis. Eur J Neurol (Jan), 25(9): 1169-1176.
- Schweser F, Raffaini Duarte Martins AL, Hagemeier J, Lin F, Hanspach J, Weinstock-Guttman B, Hametner S, Bergsland N, Dwyer MG, Zivadinov R. (2018) Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality. Neuroimage (Jan), 167: 438-452.
- Langkammer C, Schweser F, Shmueli K, Kames C, Li X, Guo L, Milovic C, Kim J, Wei H, Bredies K, Buch S, Guo Y, Liu Z, Meineke J, Rauscher A, Marques JP, Bilgic B. (2018) Quantitative susceptibility mapping: Report from the 2016 reconstruction challenge. Magn Reson Med (Jan), 79(3): 1661-1673.
- Hagemeier J, Ramanathan M, Schweser F, Dwyer MG, Lin F, Bergsland N, Weinstock-Guttman B, Zivadinov R. (2017) Iron-related gene variants and brain iron in multiple sclerosis and healthy individuals. Neuroimage Clin (Nov), 17: 530-540.
- Hanspach J, Dwyer MG, Bergsland NP, Feng X, Hagemeier J, Bertolino N, Polak P, Reichenbach JR, Zivadinov R, Schweser F. (2017) Methods for the computation of templates from quantitative magnetic susceptibility maps (QSM): Toward improved atlas- and voxel-based analyses (VBA). J Magn Reson Imaging (Nov), 46(5): 1474-1484.
- Modica CM, Schweser F, Sudyn ML, Bertolino N, Preda M, Polak P, Siebert DM, Krawiecki JC, Sveinsson M, Hagemeier J, Dwyer MG, Pol S, Zivadinov R. (2017) Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis. PLoS One (Aug), 12(8): 0182729-0182729.
- Hagemeier J, Zivadinov R, Dwyer MG, Polak P, Bergsland N, Weinstock-Guttman B, Zalis J, Deistung A, Reichenbach JR, Schweser F. (2017) Changes of deep gray matter magnetic susceptibility over 2Â years in multiple sclerosis and healthy control brain. Neuroimage Clin (Apr), 18: 1007-1016.
- Özbay PS, Deistung A, Feng X, Nanz D, Reichenbach JR, Schweser F. (2017) A comprehensive numerical analysis of background phase correction with V-SHARP. NMR Biomed (Apr), 30(4).
- Robinson SD, Bredies K, Khabipova D, Dymerska B, Marques JP, Schweser F. (2017) An illustrated comparison of processing methods for MR phase imaging and QSM: combining array coil signals and phase unwrapping. NMR Biomed (Apr), 30(4).
- Schweser F, Robinson SD, de Rochefort L, Li W, Bredies K. (2017) An illustrated comparison of processing methods for phase MRI and QSM: removal of background field contributions from sources outside the region of interest. NMR Biomed (Apr), 30(4).
- Deistung A, Schweser F, Reichenbach JR. (2017) Overview of quantitative susceptibility mapping. NMR Biomed (Apr), 30(4)
- Feng X, Deistung A, Dwyer MG, Hagemeier J, Polak P, Lebenberg J, Frouin F, Zivadinov R, Reichenbach JR, Schweser F. (2017) An improved FSL-FIRST pipeline for subcortical gray matter segmentation to study abnormal brain anatomy using quantitative susceptibility mapping (QSM). Magn Reson Imaging (Feb), 39: 110-122.
- Zivadinov R, Ramasamy DP, Benedict RR, Polak P, Hagemeier J, Magnano C, Dwyer MG, Bergsland N, Bertolino N, Weinstock-Guttman B, Kolb C, Hojnacki D, Utriainen D, Haacke EM, Schweser F. (2016) Cerebral Microbleeds in Multiple Sclerosis Evaluated on Susceptibility-weighted Images and Quantitative Susceptibility Maps: A Case-Control Study. Radiology (Dec), 281(3): 884-895.
- Langkammer C, Pirpamer L, Seiler S, Deistung A, Schweser F, Franthal S, Homayoon N, Katschnig-Winter P, Koegl-Wallner M, Pendl T, Stoegerer EM, Wenzel K, Fazekas F, Ropele S, Reichenbach JR, Schmidt R, Schwingenschuh P. (2016) Quantitative Susceptibility Mapping in Parkinson's Disease. PLoS One (Sep), 11(9): 0162460-0162460.
- Doring TM, Granado V, Rueda F, Deistung A, Reichenbach JR, Tukamoto G, Gasparetto EL, Schweser F. (2016) Quantitative Susceptibility Mapping Indicates a Disturbed Brain Iron Homeostasis in Neuromyelitis Optica - A Pilot Study. PLoS One (May), 11(5): 0155027-0155027.
- Schweser F, Deistung A, Reichenbach JR. (2016) Foundations of MRI phase imaging and processing for Quantitative Susceptibility Mapping (QSM). Z Med Phys (Mar), 26(1): 6-34.
- Klohs J, Deistung A, Ielacqua GD, Seuwen A, Kindler D, Schweser F, Vaas M, Kipar A, Reichenbach JR, Rudin M. (2016) Quantitative assessment of microvasculopathy in arcAβ mice with USPIO-enhanced gradient echo MRI. J Cereb Blood Flow Metab (Jan), 36(9): 1614-1624.
- Reichenbach JR, Schweser F, Serres B, Deistung A. (2015) Quantitative Susceptibility Mapping: Concepts and Applications. Clin Neuroradiol (Oct), 25: 225-230.
- Prell T, Hartung V, Tietz F, Penzlin S, Ilse B, Schweser F, Deistung A, Bokemeyer M, Reichenbach JR, Witte OW, Grosskreutz J. (2015) Susceptibility-weighted imaging provides insight into white matter damage in amyotrophic lateral sclerosis. PLoS One (Jun), 10(6): 0131114-0131114.
- Hagemeier J, Tong O, Dwyer MG, Schweser F, Ramanathan M, Zivadinov R. (2015) Effects of diet on brain iron levels among healthy individuals: an MRI pilot study. Neurobiol Aging (Apr), 36(4): 1678-1685.
- Topfer R, Schweser F, Deistung A, Reichenbach JR, Wilman AH. (2015) SHARP edges: recovering cortical phase contrast through harmonic extension. Magn Reson Med (Feb), 73(2): 851-856.
- Löbel U, Schweser F, Nickel M, Deistung A, Grosse R, Hagel C, Fiehler J, Schulz A, Hartig M, Reichenbach JR, Kohlschütter A, Sedlacik J. (2014) Brain iron quantification by MRI in mitochondrial membrane protein-associated neurodegeneration under iron-chelating therapy. Ann Clin Transl Neurol (Dec), 1(12): 1041-1046.
- Hagemeier J, Dwyer MG, Bergsland N, Schweser F, Magnano CR, Heininen-Brown M, Ramasamy DP, Carl E, Kennedy C, Melia R, Polak P, Deistung A, Geurts JJ, Reichenbach JR, Zivadinov R. (2013) Effect of age on MRI phase behavior in the subcortical deep gray matter of healthy individuals. AJNR Am J Neuroradiol (Nov), 34(11): 2144-2151.
- Deistung A, Schäfer A, Schweser F, Biedermann U, Güllmar D, Trampel R, Turner R, Reichenbach JR. (2013) High-Resolution MR Imaging of the Human Brainstem In vivo at 7 Tesla. Front Hum Neurosci (Oct), 7: 710-710.
- Schweser F, Dwyer MG, Deistung A, Reichenbach JR, Zivadinov R. (2013) Impact of tissue atrophy on high-pass filtered MRI signal phase-based assessment in large-scale group-comparison studies: a simulation study. Front Physics (Oct)14.
- Klohs J, Politano IW, Deistung A, Grandjean J, Drewek A, Dominietto M, Keist R, Schweser F, Reichenbach JR, Nitsch RM, Knuesel I, Rudin M. (2013) Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging. PLoS One (Jun), 8(6): 66097-66097.
- Klohs J, Politano IW, Deistung A, Grandjean J, Drewek A, Dominietto M, Keist R, Schweser F, Reichenbach JR, Nitsch RM, Knuesel I, Rudin M. (2013) Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAß Mice Using Multi-Parametric Magnetic Resonance Imaging. PLoS One (Jun), 8(6): 66097-66097.
- Schweser F, Deistung A, Sommer K, Reichenbach JR. (2013) Toward online reconstruction of quantitative susceptibility maps: superfast dipole inversion. Magn Reson Med (Jun), 69(6): 1582-1594.
- Radbruch A, Mucke J, Schweser F, Deistung A, Ringleb PA, Ziener CH, Roethke M, Schlemmer HP, Heiland S, Reichenbach JR, Bendszus M, Rohde S. (2013) Comparison of susceptibility weighted imaging and TOF-angiography for the detection of Thrombi in acute stroke. PLoS One (May), 8(5): 63459-63459.
- Deistung A, Schweser F, Wiestler B, Abello M, Roethke M, Sahm F, Wick W, Nagel AM, Heiland S, Schlemmer HP, Bendszus M, Reichenbach JR, Radbruch A. (2013) Quantitative susceptibility mapping differentiates between blood depositions and calcifications in patients with glioblastoma. PLoS One (Mar), 8(3): 57924-57924.
- Deistung A, Schäfer A, Schweser F, Biedermann U, Turner R, Reichenbach JR. (2013) Toward in vivo histology: a comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, and R2*-imaging at ultra-high magnetic field strength. Neuroimage (Jan), 65: 299-314.
- Langkammer C, Schweser F, Krebs N, Deistung A, Goessler W, Scheurer E, Sommer K, Reishofer G, Yen K, Fazekas F, Ropele S, Reichenbach JR. (2012) Quantitative susceptibility mapping (QSM) as a means to measure brain iron? A post mortem validation study. Neuroimage (Sep), 62(3): 1593-1599.
- Schweser F, Sommer K, Deistung A, Reichenbach JR. (2012) Quantitative susceptibility mapping for investigating subtle susceptibility variations in the human brain. Neuroimage (Sep), 62(3): 2083-2100.
- Klohs J, Deistung A, Schweser F, Grandjean J, Dominietto M, Waschkies C, Nitsch RM, Knuesel I, Reichenbach JR, Rudin M. (2011) Detection of cerebral microbleeds with quantitative susceptibility mapping in the ArcAbeta mouse model of cerebral amyloidosis. J Cereb Blood Flow Metab (Dec), 31(12): 2282-2292.
- Schweser F, Deistung A, Lehr BW, Reichenbach JR. (2011) Quantitative imaging of intrinsic magnetic tissue properties using MRI signal phase: an approach to in vivo brain iron metabolism?. Neuroimage (Feb), 54(4): 2789-2807.
- Schweser F, Deistung A, Lehr BW, Reichenbach JR. (2010) Differentiation between diamagnetic and paramagnetic cerebral lesions based on magnetic susceptibility mapping. Med Phys (Oct), 37(10): 5165-5178.
- Graesslin I, Glaesel D, Biederer S, Schweser F, Vernickel P, Bornert P, Annighoefer B, Stahl H, Dingemans H, Mens G, Harvey P, Katscher U. (2008) SAR in Parallel Transmission. PIERS (Jan), 4(6): 681.
Books and Book Chapters:
- Schweser F, Preda M, Zivadinov R. (2018) Susceptibility Weighted MRI in Rodents at 9.4 Tesla. In: Methods in Molecular Biology—Preclinical MRI: Methods and Protocols. Springer
Abstracts:
- Jochmann T, Haueisen J, Zivadinov R, Schweser F. (2021) DEEPOLE QUASAR–A deep learning-based approach for quantitative susceptibility and non-susceptibility phase mapping. 5th International Workshop on MRI Phase Contrast and QSM. Seoul, (Aug)Oral
- Salman F, Bergsland N, Dwyer MG, Weinstock-Guttman B, Zivadinov R, Schweser F. (2021) Decline of both iron concentration and iron content within the thalamus of patients with mul-tiple sclerosis over two years. Proc Intl Soc Mag Reson Med. (Aug), (2805)Poster
- Jochmann T, Jakimovski D, Küchler N, Zivadinov R, Haueisen J, Schweser F. (2021) Quantitative mapping of susceptibility and non-susceptibility frequency from gradient-echo phase images. 12th Ultrahigh Field Magnetic Resonance Symposium. Berlin, (Aug), (13)Poster
- Jochmann T, Schweser F, Küchler N, Jakimovski D, Zivadinov R, Haueisen J. (2021) Mapping Magnetic Susceptibility and Non-Susceptibility Sources from MRI Frequency Shift with Physics-informed Deep Learning. 6th International Workshop on Optimization and Inverse Problems in Electromagnetism. (Aug)Oral
- Benslimane I, Jochmann T, Zivadinov R, Schweser F. (2021) Unsupervised physics-informed deep learning (N=1) for solving inverse qMRI problems–Relaxometry and field mapping from multi-echo data. Proc Intl Soc Mag Reson Med. (Aug), (330)Oral
- Jochmann T, Jakimovski D, Küchler N, Zivadinov R, Haueisen J, Schweser F. (2021) Quantitative mapping of susceptibility and non-susceptibility frequency with DEEPOLE QUASAR. Proc Intl Soc Mag Reson Med. (Aug), (789)Oral
- Dhanraj R, Pol S, Paredes EC, Punugu V, Schweser F, Modica C, Bertolino N, Preda M, Dwyer MG, Zivadinov R. (2021) Detection of pathology sensitive multimodal MRI measures in Theiler’s Murine Encephalo-myelitis Virus Model of Chronic Demyelination. American Academy of Neurology (AAN). (Aug), (2803)Poster
- Choudhary P, Pol S, Preda M, Zivadinov R, Schweser F. (2020) Detection of metabolic alterations in the thalamus of the TMEV mouse model of multiple scle-rosis at 9.4 Tesla. Proc Intl Soc Mag Reson Med. (Aug), (2937)Poster
- Jochmann T, Haueisen J, Schweser F. (2020) How to train a Deep Convolutional Neural Network for Quantitative Susceptibility Mapping (QSM). Proc Intl Soc Mag Reson Med. (Aug), (3195)Poster
- Beadnall HN, Weinstock-Guttman B, Wang C, Hagemeier J, Bergsland N, Jakimovski D, Ra-manathan M, Ly L, Dwyer MG, Schweser F, Hardy T, Benedict RHB, Barnett M, Zivadinov R. (2020) Fingolimod therapy in real-world relapsing multiple sclerosis patients: cross-sectional and longitudinal assessment of cognition, quantitative MRI and deep gray matter quantitative susceptibility mapping. ECTRIMS-ACTRIMS 2020 (MSVirtual 2020). (Aug)Poster
- Zivadinov R, Schweser F, Dwyer MG, Pol S. (2020) Effect of anti-muCD52 antibody on brain and spinal cord imaging markers of neurodegenera-tion, microglia, and macrophage activation in the Theiler’s Murine Encephalomyelitis Virus model of chronic demyelination. American Academy of Neurology (AAN). (Aug), (2486)Poster
- Wack A, Schweser F, Slavakis K, McNerny K, Muldoon S, McGranor C, Kelly E, Miletich R, Wack D. (2020) Exploring Effects of Visual Based Activities Using DTI and Resting State Imaging. OHBM. (Aug), (1647)Poster
- Wack D, McNerny K, Slavakis K, Muldoon S, Schweser F, Wack A, McGranor C, Kelly E, Miletich R. (2020) Resting State and DTI Imaging of Speech in Noise. OHBM. (Aug), (1643)Poster
- Baader EF, Jochmann T, Haueisen J, Zivadinov R, Schweser F. (2020) U3-Net for Deep Vector QSM – Solving the Susceptibility Tensor Phase Model in Single-Orientation MRI. (Aug), (3202)Poster
- Jochmann T, Kuechler N, Haueisen J, Schweser F. (2020) SOJU-Net—Denoising MR phase images with physics-informed deep learning using artificial Rician noise augmentation. Proc Intl Soc Mag Reson Med. (Aug), (3196)Poster
- Küchler N, Haueisen J, Schweser F, Jochmann T. (2020) A Fourier transformation based convolutional neural network layer for physics-informed deep learning of magnetic dipole inversion. German Society for Biomedical Engineering. (Aug), (p1570638759)Poster
- Chandrasekharan P, Schweser F. (2020) Magnetic Resonance Imaging as a Tool to Evaluate the Extent of Brain Injury in Term and Pre-term Ovine Models of Asphyxia. Eastern Society for Pediatric Research Scientific Meeting. (Aug)Poster
- Zivadinov R, Schweser F, Dwyer MG, Pol S. (2020) Detection of microglia activation in the Theiler’s Murine Encephalomyelitis Virus model of chronic demyelination using ultra-small superparamagnetic iron oxides (USPIO) nanoparticle enhanced high-field imaging. American Academy of Neurology (AAN). Toronto, (Aug), (2)Oral
- Salman F, Zivadinov R, Bergsland N, Dwyer MG, Weinstock-Guttman B, Schweser F. (2020) Trajectories of magnetic susceptibility in the pulvinar provide further evidence for accelerated decline of thalamic iron in multiple sclerosis. Proc Intl Soc Mag Reson Med. (Aug), (1385)Poster
- Pol S, Liang Q, Schweser F, Schubert A, Preda M, Sveinsson M, Ramsamay D, Dwyer MG, Weckbecker G, Zivadinov R. (2020) Subcutaneous anti-CD20 antibody treatment delays gray matter atrophy in human myelin oli-godendrocyte glycoprotein-induced experimental Autoimmune encephalomyelitis mice. American Academy of Neurology (AAN). (Aug), (2130)Poster
- Rajabzadeh-Oghaz H, Chandra AR, Gutierrez L, Schweser F, Ionita CN, Siddiqui A, Tutino V, Gimi B, Krol A. (2019) High-resolution MRI of the mouse cerebral vasculature to study hemodynamic-induced vascular remodeling. (Jan) 49
- Murdoch JB, Schweser F, Saleh MG, Edden, RAE. (2019) LCModel comparison of MEGA-PRESS and HERMES for GABA (and GSH) editing at 3T. (Jan) 2237
- Choudhary P, Pol S, Preda M, Sveinsson M, Zivadinov R, Schweser F. (2019) Longitudinal 9.4 Tesla 1H MRS in the thalamus of the Theiler’s encephalomyelitis virus (TMEV) mouse model of multiple sclerosis. (Jan) 3200
- Choudhary P, Weinstock NI, Preda M, Shin D, Zivadinov R, Wrabetz L, Schweser F. (2019) Longitudinal Multi-modal Multi-parametric Imaging of the Twitcher mouse model of Krabbe Disease. (Jan) 25
- Prakash Krishnan Muthaiah V, Schweser F, Preda M. (2019) Optimization of structural imaging on Chinchilla Lanigera as a pre-clinical model of Blast TBI. (Jan)
- Schweser F, Jochmann T, Zivadinov R. (2019) Overcoming the Rician Noise Bias of T2* Relaxometry with an Artificial Neural Network (ANN). (Jan) 4854
- Choudhary P, Weinstock NI, Preda M, Wrabetz L, Zivadinov R, Schweser F. (2019) Pre- and post-symptomatic longitudinal metabolic assessment of the Twitcher mouse model of Krabbe Disease at 9.4 Tesla. (Jan) 3200
- Smith Z, Bertolino N, Pol S, Preda M, Sveinsson M, Zivadinov R, Schweser F. (2019) Preclinical detection of leptomeningeal inflammation in the myelin oligodendrocyte glycoprotein (MOG) induced experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). (Jan) 3222
- Shi R, Jung J-H, Schweser F. (2019) Reduction of Gibbs artifacts with the Domain Decomposition Fourier Continuation Method. (Jan) 2459
- Marques, JP, Bilgic B, Meineke J, Milovic C, Chan K-S, Langkammer C, Schweser F. (2019) Towards QSM Challenge 2.0: Creation and Evaluation of a Realistic Magnetic Susceptibility Phantom. (Jan) 1122
- Jochmann T, Haueisen J, Zivadinov R, Schweser F. (2019) U2-Net for DEEPOLE QUASAR–A Physics-Informed Deep Convolutional Neural Network that Disentangles MRI Phase Contrast Mechanisms. (Jan) 320
Professional Memberships:
- Upstate New York Association Of Physicist In Medicine (UNYAPM) (2021–present)
- American Association of University Professors (AAUP) (2021–present)
- American Academy of Neurology (AAN) (2016–present)
- Association of the friends & sponsors of the Friedrich Schiller University Jena (2014–present)
- German Association of University Professors and Lecturers (DHV) (2013–present)
- German Society for Medical Physics (DGMP) (2012–present)
- European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) (2011–present)
- International Society for Magnetic Resonance in Medicine (ISMRM) (2010–present)
- German chapter of the ISMRM (DS-ISMRM) (2009–present)
- German Physical Society (DPG) (2002–present)
Presentations:
- "Ironing Out Iron in Multiple Sclerosis: There Is Too Much Brain Iron! … or Is There Not Enough?" Neurology Grand Rounds (2021)
- "Multimodal multiparametric brain mapping for pre-symptomatic diagnosis and treatment development in Krabbe Disease" Clinical and Translational Science Award Symposium (2019)
Service Activities:
- National Institutes of Health 2022/01 Clinical Neuroimmunology and Brain Tumors (CNBT) meeting; Special Emphasis Panel/Scientific Review Group Member (2021)
- Faculty Senate; Senator (2021–present)
- Jezzard, P. & Choi, I.-Y. (Eds.). Advanced Neuro Magnetic Resonance Techniques and Applications. Academic Press (Elsevier).; Ad Hoc Book Chapter Reviewer (2021)
- The New England Journal of Medicine; Ad hoc Manuscript Reviewer (2021–present)
- Working Group for the procurement of a new human 3T MRI; Member (2020–present)
- Frontiers in Neuroscience; Ad hoc Manuscript Reviewer (2020–present)
- Annual Meeting of the International Society for Magnetic Resonance in Medicine Educational session: MR Physics for Scientists I.; Session chair (2020)
- Annual Meeting of the International Society for Magnetic Resonance in Medicine Oral scientific session: Contrast Mechanisms—Acquisition and Fitting Methods; Session chair (2020)
- Human Brain Mapping; Ad hoc Manuscript Reviewer (2020–present)
- European Journal of Neurology; Ad hoc Manuscript Reviewer (2019–present)
- Steering committee for the 2022 EPT-QSM Workshop in Lucca, Italy; Member (2019–present)
- Northeast Regional Conference on Complex Systems; Program Committee Member (2019–2020)
- Heliyon, Cell Press; Associate Editor for Clinical Research/Medical Imaging (2019–present)
- Journal of the Neurological Sciences; Ad hoc Manuscript Reviewer (2018–present)
- Frontiers Human Neuroscience; Ad hoc Manuscript Reviewer (2018–present)
- Magnetic Resonance Imaging; Ad hoc Manuscript Reviewer (2018–present)
- Steering Committee of the Clinical and Translational Science Institute; Alternate (2017–present)
- Neuroradiology; Ad hoc Manuscript Reviewer (2016–present)
- Buffalo Neuroimaging Analysis Center; Patient advisory council member (2016–present)
- Steering Committee of the Center for Biomedical Imaging (2015–present)
- NeuroImage: Clinical; Ad hoc Manuscript Reviewer (2015–present)
- PLOS ONE; Ad hoc Manuscript Reviewer (2015–present)
- International Journal of Molecular Sciences; Ad hoc Manuscript Reviewer (2015–present)
- BMC Medical Imaging; Ad hoc Manuscript Reviewer (2015–present)
- NMR in Biomedicine; Ad hoc Manuscript Reviewer (2014–present)
- Journal of Alzheimer's disease; Ad hoc Manuscript Reviewer (2014–present)
- Magnetic Resonance Materials in Physics, Biology and Medicine; Ad hoc Manuscript Reviewer (2014–present)
- IEEE Transactions on Medical Imaging; Ad hoc Manuscript Reviewer (2014–present)
- European Radiology; Ad hoc Manuscript Reviewer (2014–present)
- Journal of Magnetic Resonance Imaging; Ad hoc Manuscript Reviewer (2014–present)
- Magnetic Resonance in Medicine; Ad hoc Manuscript Reviewer (2014–present)
- Neuroimage; Ad hoc Manuscript Reviewer (2014–present)
- Journal of Neuroimaging; Ad hoc Manuscript Reviewer (2014–present)
- ISMRM Ad Hoc Committee on Standards for Quantitative MR; Committee Member (2014–2015)
- ISMRM Electro-Magnetic Tissue Properties Study Group; Committee Member (2014–2015)
- Second international workshop on MRI phase contrast and quantitative susceptibility mapping; Committee Member (2013)
- Frontiers in Brain Imaging Methods; Ad hoc Manuscript Reviewer (2013–present)
- IEEE Transactions on Biomedical Engineering; Ad hoc Manuscript Reviewer (2013–present)
- Journal of Magnetic Resonance Imaging; Ad hoc Manuscript Reviewer (2013–present)
- Frontiers in Biomedical Physics; Editorial Board Member (2013–present)
- Magnetic Resonance in Medicine; Ad hoc Manuscript Reviewer (2012–present)
- NeuroImage; Ad hoc Manuscript Reviewer (2012–present)
- European Radiology; Ad hoc Manuscript Reviewer (2012–present)
- First international workshop on MRI phase contrast and quantitative susceptibility mapping; Organizing Committee Member (2010–2011)
- Zeitschrift fuer Medizinische Physik; Ad hoc Manuscript Reviewer (2010–present)
- Del Monte Institute for Neuroscience Pilot Program, The University of Rochester, USA; Scientific Grant Reviewer
- Dutch Foundation for Fundamental Research on Matter, FOM, The Netherlands; Scientific Grant Reviewer
- FWF Austrian Science Fund, Austria; Scientific Grant Reviewer
- Israeli Ministry of Science & Technology, French-Israeli Cooperation program, Israel; Scientific Grant Reviewer
- National Sciences and Engineering Research Council of Canada, Discovery Grants, Canada; Scientific Grant Reviewer
- PennState Clinical and Translational Science Institute, CTSA Pilot Studies Program, USA; Scientific Grant Reviewer
- Stanford Synchrotron Radiation Lightsource, USA; Scientific Grant Reviewer
- Swiss National Science Foundation (SNSF), Spark program, Switzerland; Scientific Grant Reviewer
- The Netherlands Organization for Health Research and Development (ZonMw), The Investment Subsidy ZonMw/NWO BIG, The Netherlands; Scientific Grant Reviewer
- UK Medical Research Council, Clinical Research Training Fellowship—Pre Doc; Scientific Grant Reviewer