Ali A. El Solh MD, MPH
Ali A. El Solh
MD, MPH
Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Pulmonary & Critical Care Medicine; Sleep Medicine
Professional Summary:
I hold clinical appointment at the VA WNY Healthcare System. Aside of my administrative duties, I attend and supervise the sleep clinic at the VA
My research focuses on the association between sleep apnea and cardiovascular diseases. My laboratory examines the burden of oxidative stress on endothelial function and the link to endothelial apoptosis. As part of a VA merit review grant, we are engaged in determining the impact of obstructive sleep apnea on the manifestations of post-traumatic stress disorder (PTSD) in veterans and whether treatment of sleep apnea alleviates the debilitating symptoms of PTSD. Toward that goal, we have adopted a patented screening tool to identify patients with sleep apnea.
My research in the critical care arena involves the epidemiology and risk factors of Pseudomonas infections with the type III secretory system. The goal is to develop a rapid diagnostic tool to identify these organisms early in the course of infection. My other projects include studying the role of adjuvant treatment with corticosteroids in the management of severe community acquired pneumonia, such as nursing home acquired pneumonia, the management of morbidly obese critically ill patients and the long-term outcomes of elderly patients after treatment from a critical care ailment.
Education and Training:
- MPH, Public Health, Medical College of Wisconsin (2002)
- MD, Medicine, American University of Beirut, Lebanon (1989)
- BCs, American University of Beirut, Lebanon (1985)
Employment:
- Associate Chief of Staff for Research and Devolpment, Research and Devolpment, VA Western New York Healthcare System (2013-present)
- Professor of Medicine, Medicine, University at Buffalo (2011-present)
- Research Professor, School of Health Related Professions, University at Buffalo (2008-present)
- Director, James P. Nolan Clinical Research Center, University at Buffalo (2001-present)
- Attending Physician/Pulmonary Service, Pulmonary, VAMC (1996-present)
- Interim Chief of Staff, Medicine, VA Western New York Healthcare System (2014–2016)
- Associate Professor, Medicine, University at Buffalo (2004–2011)
- Director/Medical ICU, Medical ICU, ECMC (1998–2008)
- Member/Critical Care Committee, Critical Care, ECMC (1998–2008)
- Assistant Professor, Medicine, University at Buffalo (1998–2004)
- Clinical Assistant Professor, Medicine, University at Buffalo (1997–1998)
- Attending Physician, Medicine, Buffalo General Hospital (1996–1998)
- Clinical Instructor, Medicine, University at Buffalo (1996–1997)
Awards and Honors:
- Visionary Innovator (2008)
Research Expertise:
- Health care associated pneumonia
- Morbid obesity in the intensive care unit
- Sleep disordered breathing in cardiovascular disease
Grants and Sponsored Research:
- October 2012–September 2015
A Randomized study comparing CPAP to oral appliance in patients with PTSD and sleep apnea
Veterans Affairs
Role: Principal Investigator - January 2010–January 2015
Randomized, Placebo-Controlled, Double-Blind Clinical Trial to Evaluate the Safety and Efficacy of Low-Dose Methylprednisolone in Hospitalized Veterans with Severe Community-Acquired Pneumonia. VA Cooperative study Program #574.
Veterans Affairs
Role: Principal Investigator - May 2011–May 2013
VA Cooperative Study No. 574ESCAPe [Extended Steroid (in) CAP(e)]
Veterans Administration
Role: Principal Investigator - January 2010–January 2011
Sleep apnea screening in patients with ischemic cardiac diseases. HSR&D Merit Review: PPO 10-087-1
Role: Principal Investigator - January 1999–December 2000
Obstructive sleep apnea in ischemic heart disease
Research for Health in Erie County
Role: Principal Investigator - January 1998–December 1999
The use of neural network in the diagnosis of sleep apnea
Research for Health in Erie County
Role: Principal Investigator - January 2007
Tigecycline Inhibits Staphylococcal Exotoxin-Induced Cytokines: An Anti-Inflammatory Property.
Wyeth
Role: Principal Investigator - January 2005
Linezolid In The Treatment Of Subjects With Nosocomial Pneumonia Proven To Be Due To Methicillin-Resistant Staphylococcus Aureus. Pfizer Pharmaceuticals Group.
Role: Principal Investigator - PRECEPT-D
Department of Veterans Affairs
Role: Principal Investigator
Patents:
- Articial Network Artificial neural network for predicting respiratory disturbances
Journal Articles:
- Jaoude PE, Vermont LN, Porhomayon J, El Solh AA. Sleep-Disordered Breathing in Patients with Post Traumatic Stress Disorder Ann Am Thorac Soc. 2014.
- Reddy R, Adamo D, Kufel T, Porhomayon J, El-Solh AA, El Solh AA. Treatment of opioid-related central sleep apnea with positive airway pressure: a systematic review. J Opioid Manag. 2014; 10(1).
- Porhomayon J, Nader ND, El Solh AA, Hite M, Scott J, Silinskie K. Pre- and post-intervention study to assess the impact of a sedation protocol in critically ill surgical patients. J Surg Res. 2013; 184(2).
- Hattemer A, Hauser A, Diaz M, Scheetz M, Shah N, Allen JP, Porhomayon J, El-Solh AA, El Solh AA. Bacterial and clinical characteristics of health care- and community-acquired bloodstream infections due to Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2013; 57(8).
- Porhomayon J, El Solh AA. Guideline-concordant antimicrobial therapy for healthcare-associated pneumonia: a systematic review and meta-analysis. Lung. 2013; 191(3).
- Porhomayon J, Akinnusi M, Kufel TJ, Popescu GK, El Solh AA. Effects of dietary weight loss on obstructive sleep apnea: a meta-analysis. Sleep Breath. 2013; 17(1).
- Porhomayon J, Papadakos P, Nader ND, El Solh AA. Weaning failure: My heart is not up to it. Chron Respir Dis. 2013; 10(3).
- Porhomayon J, El-Masri I, El Solh AA. Pneumonia immunization in older adults: review of vaccine effectiveness and strategies. Clin Interv Aging. 2012; 7.
- Porhomayon J, Saliba R, El Solh AA. Sleep disorders in morbid obesity. Eur J Intern Med. 2012; 23(3).
- Porhomayon J, El Solh AA, Nader ND. Assessment of Cardiac Output Monitoring Devices for Critically ill Surgical Patients.. Journal of Trauma, Injury, Infection, and Critical Care. 2010.
- Porhomayon J., El Solh AA, Nader N.. National survey to assess the content and availability of difficult airway cart in critical care.. Journal of Anesthesia. 2010; 24.
- Porhomayon J, El Solh AA, Nader ND. Application of airway pressure release ventilation.. Lung. 2010; 188.
- El Solh AA, Dhillon RS, Aquilina AT, Ramadan F, Patricia Nowak, Joan Davies. Impact of Invasive Strategy on Management of Antimicrobial Treatment Failure in Institutionalized Older People with Severe Pneumonia. American Journal Of Respiratory and Critical Care Medicine. 2002.
- Akinnusi M, El-Masri AR, Lawson Y, El-Solh AA, El Solh AA. Association of overlap syndrome with incident atrial fibrillation. Intern Emerg Med. 2020.
- El-Solh AA, Lawson Y, Wilding GE, El Solh AA. Impact of low arousal threshold on treatment of obstructive sleep apnea in patients with post-traumatic stress disorder. Sleep Breath. 2020.
- Hassinger AB, Bletnisky N, Dudekula R, El-Solh AA, El Solh AA. Selecting a pharmacotherapy regimen for patients with chronic insomnia. Expert Opin Pharmacother. 2020; 21(9).
- El-Solh AA, O'Brien N, Akinnusi M, Patel S, Vanguru L, Wijewardena C, El Solh AA. Predictors of cognitive behavioral therapy outcomes for insomnia in veterans with post-traumatic stress disorder. Sleep Breath. 2019; 23(2).
- Akinnusi M, El Solh AA, El Solh AA. Drug treatment strategies for insomnia in patients with post-traumatic stress disorder. Expert Opin Pharmacother. 2019; 20(6).
- Hill AT, Gold PM, El Solh AA, Metlay JP, Ireland B, Irwin RS, El Solh AA. Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report. Chest. 2019; 155(1).
- El-Solh AA, El Solh AA. Management of nightmares in patients with posttraumatic stress disorder: current perspectives. Nat Sci Sleep. 2018; 10.
- Hill AT, Gold PM, El Solh AA, Metlay JP, Ireland B, Irwin RS, El Solh AA. Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report. Chest. 2018.
- El-Solh AA, Riaz U, Roberts J, El Solh AA. Sleep Disorders in Patients With Posttraumatic Stress Disorder. Chest. 2018.
- El-Solh AA, Adamo D, Kufel T, El Solh AA. Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder. Sleep Breath. 2018; 22(1).
- El-Solh AA, Homish GG, Ditursi G, Lazarus J, Rao N, Adamo D, Kufel T, El Solh AA. A Randomized Crossover Trial Evaluating Continuous Positive Airway Pressure Versus Mandibular Advancement Device on Health Outcomes in Veterans With Posttraumatic Stress Disorder. J Clin Sleep Med. 2017; 13(11).
- Liu P, Capitano B, Stein A, El Solh AA. Clinical outcomes of linezolid and vancomycin in patients with nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus stratified by baseline renal function: a retrospective, cohort analysis. BMC Nephrol. 2017; 18(1).
- El Solh AA, Vermont L, Homish GG, Kufel TJ. The effect of continuous positive airway pressure on post-traumatic stress disorder symptoms in veterans with post-traumatic stress disorder and obstructive sleep apnea: a prospective study. Sleep Med. 2017; 33.
- Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB, Napolitano LM, O'Grady NP, Bartlett JG, Carratalà J, El Solh AA, Ewig S, Fey PD, File TM, Restrepo MI, Roberts JA, Waterer GW, Cruse P, Knight SL, Brozek JL, El Solh AA. Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis. 2016; 63(5).
- Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB, Napolitano LM, O'Grady NP, Bartlett JG, Carratalà J, El Solh AA, Ewig S, Fey PD, File TM, Restrepo MI, Roberts JA, Waterer GW, Cruse P, Knight SL, Brozek JL, El Solh AA. Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis. 2016; 63(5).
- Lal A, Jaoude PE, El Solh AA. Prolonged versus Intermittent Infusion of β-Lactams for the Treatment of Nosocomial Pneumonia: A Meta-Analysis. Infect Chemother. 2016; 48(2).
- Vertigan AE, Murad MH, Pringsheim T, Feinstein A, Chang AB, Newcombe PA, Rubin BK, McGarvey LP, Weir K, Altman KW, Weinberger M, Irwin RS, Adams TM, Altman KW, Barker AF, Birring SS, Blackhall F, Bolser DC, Boulet LP, Braman SS, Brightling C, Callahan-Lyon P, Canning BJ, Chang AB, Coeytaux R, Cowley T, Davenport P, Diekemper RL, Ebihara S, El Solh AA, Escalante P, Feinstein A, Field SK, Fisher D, French CT, Gibson P, Gold P, Gould MK, Grant C, Harding SM, Harnden A, Hill AT, Irwin RS, Kahrilas PJ, Keogh KA, Lane AP, Lim K, Malesker MA, Mazzone P, Mazzone S, McCrory DC, McGarvey L, Molasiotis A, Murad MH, Newcombe P, Nguyen HQ, Oppenheimer J, Prezant D, Pringsheim T, Restrepo MI, Rosen M, Rubin B, Ryu JH, Smith J, Tarlo SM, Vertigan AE, Wang G, Weinberger M, Weir K, Wiener RS, El Solh AA. Somatic Cough Syndrome (Previously Referred to as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children: CHEST Guideline and Expert Panel Report. Chest. 2015; 148(1).
- French CT, Diekemper RL, Irwin RS, Adams TM, Altman KW, Barker AF, Birring SS, Blackhall F, Bolser DC, Boulet LP, Braman SS, Brightling C, Callahan-Lyon P, Canning BJ, Chang AB, Coeytaux R, Cowley T, Davenport P, Diekemper RL, Ebihara S, El Solh AA, Escalante P, Feinstein A, Field SK, Fisher D, French CT, Gibson P, Gold P, Gould MK, Grant C, Harding SM, Harnden A, Hill AT, Irwin RS, Kahrilas PJ, Keogh KA, Lane AP, Lim K, Malesker MA, Mazzone P, Mazzone S, McCrory DC, McGarvey L, Molasiotis A, Murad MH, Newcombe P, Nguyen HQ, Oppenheimer J, Prezant D, Pringsheim T, Restrepo MI, Rosen M, Rubin B, Ryu JH, Smith J, Tarlo SM, Vertigan AE, Wang G, Weinberger M, Weir K, El Solh AA. Assessment of Intervention Fidelity and Recommendations for Researchers Conducting Studies on the Diagnosis and Treatment of Chronic Cough in the Adult: CHEST Guideline and Expert Panel Report. Chest. 2015; 148(1).
- Nader ND, Porhomayon J, El Solh AA, Adlparvar G, Jaoude PE. The impact of high versus low sedation dosin strategy on Post cognitive dysfunction in Survivors of Intensive Care Units: A Systemic Review and Meta-Analysis. Cardiovasc Thorac Res. 2015; 7(2).
- Alhajhusain A, Ali AW, Najmuddin A, Hussain K, Aqeel M, El Solh AA. Timing of tracheotomy in mechanically ventilated critically ill morbidly obese patients. Crit Care Res Pract. 2014; 2014.
- Troitino A, Labedi N, Kufel TJ, El Solh AA. Positive airway pressure therapy in patients with opioid-related central sleep apnea. Sleep Breath. 2014; 18(2).
- Anandam A, Patil M, Akinnusi M, Jaoude P., El Solh AA. Cardiovascular mortality in obstructive sleep apnoea treated with continuous positive airway pressure or oral appliance: an observational study. Respirology. 2013; 18(8).
- Akinnusi M, Jaoude P, Kufel T, El-Solh AA, El Solh AA. Toll-like receptor activity in patients with obstructive sleep apnea. Sleep Breath. 2013; 17(3).
- Troitino A, Labedi N, Kufel T, El-Solh AA, El Solh AA. Positive airway pressure therapy in patients with opioid-related central sleep apnea. Sleep Breath. 2013.
- Mador MJ, Goplani S, Gottumukkala VA, El-Solh AA, Akashdeep K, Khadka G, Abo-Khamis M, El Solh AA. Postoperative complications in obstructive sleep apnea. Sleep Breath. 2013; 17(2).
- Mador MJ, Goplani S, Gottumukkala VA, El Solh AA, Akashdeep K, Khadka G, Abo-Khamis M. Postoperative complications in obstructive sleep apnea Sleep Breath. 2013; 17(2).
- Akinnusi M, Saliba R, El-Solh AA, El Solh AA. Emerging therapies for obstructive sleep apnea. Lung. 2012; 190(4).
- Porhomayon J, El-Solh A, Papadakos Pj, Nader ND. Analytic Review: Cardiac Output Devices. Intern J Emerg Me. 2012; 7(2).
- Ioachimescu OC, El Solh AA. Pharmacotherapy of insomnia. Expert Opin Pharmacother. 2012; 13(9).
- El Solh AA, Hattemer A, Hauser AR, Alhajhusain A, Vora H. Clinical outcomes of type III Pseudomonas aeruginosa bacteremia. Crit Care Med. 2012; 40(4).
- Mador MJ, Goplani S., Gottumukkala V.A., El Solh AA, Akashdeep K, Khadka G, Abo Khamis M.. Postoperative complications in obstructive sleep apnea.. Sleep and Breathing. 2012.
- Porhomayon J, El-Solh A, Cangani S, Nader ND. Surgical Outcome in Obstructive Sleep Apnea. Lung. 2011; 189(5).
- El-Solh AA, El Solh AA. Association between pneumonia and oral care in nursing home residents. Lung. 2011; 189(3).
- El Solh AA, Alhajhusain A, Saliba RG, Drinka P. Physicians‘ attitudes toward guidelines for the treatment of hospitalized nursing home-acquired pneumonia. J Am Med Dir Assoc. 2011; 12(4).
- El-Solh AA, Alhajhusain A, Saliba RG, Drinka P, El Solh AA. Physicians' attitudes toward guidelines for the treatment of hospitalized nursing home-acquired pneumonia. J Am Med Dir Assoc. 2011; 12(4).
- El Solh AA, Vora H., Knight III PR, Porhomayon J. Diagnostic utility of serum procalcitonin levels in pulmonary aspiration syndromes.. Critical Care Medicine. 2011; 39.
- El Solh AA, Moitheennazima B., Akinnusi M., Churder P., Lafornara A.. Combined oral appliance and positive airway pressure therapy for obstructive sleep apnea: a pilot study.. Sleep and Breathing. 2011; 15.
- Akinnusi M., Hattemer A., Gao W., El Solh AA. Linezolid modulation of lung innate immunity in a murine model of methicillin-resistant staphylococcus aureus pneumonia.. Critical Care Medicine. 2011; 39.
- El Solh AA. Nursing home acquired pneumonia: approach to management.. Current Opinion in Infectious Diseases. 2011; 24.
- El Solh AA, Alhajhusain A., Saliba, Drinka P.. Physicians’ attitudes toward guidelines for the treatment of hospitalized nursing-home acquired pneumonia.. . Journal of the American Medical Directors Association (in press). 2011; 12(4).
- El Solh AA, Niederman MS, Drinka P. Management of pneumonia in the nursing home. Chest. 2010; 138(6).
- El Solh AA, Ayyar L, Akinnusi M, Relia S, Akinnusi O. Positive airway pressure adherence in veterans with posttraumatic stress disorder. Sleep. 2010; 33(11).
- Drinka PJ, El Solh AA. The tongue, oral hygiene, and prevention of pneumonia in the institutionalized elderly. J Am Med Dir Assoc. 2010; 11(7).
- El Solh AA, Akinnusi ME, Moitheennazima B, Ayyar L, Relia S. Endothelial function in patients with post-CPAP residual sleepiness. J Clin Sleep Med. 2010; 6(3).
- El-Solh AA, Peter M, Alfarah Z, Akinnusi ME, Alabbas A, Pineda LA, El Solh AA. Antibiotic prescription patterns in hospitalized patients with nursing home-acquired pneumonia. J Hosp Med. 2010; 5(3).
- Albertson T., Dean N., El Solh AA, Gotfried M., Kaplan C., Niederman M.. Fluoroquinolones in the management of community-acquired pneumonia.. International Journal of Clinical Practice. 2010; 64.
- El Solh AA, Jaoude PE. Bicarbonate therapy in the treatment of septic shock.. Internal and Emergency Medicine. 2010; 5.
- El Solh AA, Ayyar L., Akinnusi M., Relia S., Akinnusi. Positive airway adherence in veterans with post traumatic stress disorder.. Sleep. 2010; 33.
- El Solh AA. Infectious pleural effusions can be identified by sTREM-1 levels.. Respiratory Medicine. 2010; 104.
- El Solh AA, Akinnusi M., Moitheennazima B., Ayyar L., Relia S.. Endothelial function in men with post-CPAP residual sleepiness.. Journal of Clinical Sleep Medicine. 2010; 6.
- Jaoude PE, Knight P., Ohtake P., El Solh AA. Biomarkers in the diagnosis of aspiration syndromes.. Expert Review of Molecular Diagnostics. 2010; 10.
- El Solh AA. The tongue, oral hygiene and prevention of pneumonia in the institutionalized elderly.. Journal of the American Medical Directors Association. 2010.
- El Solh AA, Niederman M., Drinka P.. Management of pneumonia in the nursing home.. Chest. 2010.
- El Solh AA, Alhajhusain A., Abou Jaoude P., Drinka P.. Validity of severity scores in hospitalized patients with nursing home acquired pneumonia.. Chest. 2010; 138.
- El Solh AA. Airway management in the obese patient. Clin Chest Med. 2009; 30(3).
- El Solh AA, Alhajhusain A. Update on the treatment of Pseudomonas aeruginosa pneumonia. J Antimicrob Chemother. 2009; 64(2).
- El Solh AA. Ceftobiprole: a new broad spectrum cephalosporin. Expert Opin Pharmacother. 2009; 10(10).
- El Solh AA, El Solh AA. Nursing home-acquired pneumonia. Semin Respir Crit Care Med. 2009; 30(1).
- El Solh AA, Akinnusi M., Alfarah Z., Patel A.. Impact of antibiotic guidelines on outcomes of hospitalized patients with nursing home acquired pneumonia.. Journal of the American Geriatrics Society. 2009; 77.
- El Solh AA, Amsterdam D., Alhajhusain A., Akinnusi M., Saliba R., Lynch S., Wiener-Kronish J.. Matrix metalloproteases in bronchoalveolar lavage fluid of patients with type III Pseudomonas aeruginosa pneumonia.. Journal of Infection. 2009; 59.
- El Solh AA, Akinnusi M., Patel A., Bhat A., Ten Brock E. Predicting optimal CPAP by neural network reduces titration failure: a randomized study.. Sleep and Breathing. 2009; 13(4).
- Saliba R., Paasch L., El Solh AA. Tigecycline attenuates staphylococcal superantigen-induced T-cell proliferation and production of cytokines and chemokines.. Immunopharmacology and Immunotoxicology. 2009; 31(4).
- Akinnusi ME, Paasch LL, Szarpa KR, Wallace PK, El Solh AA. Impact of Nasal Continuous Positive Airway Pressure Therapy on Markers of Platelet Activation in Patients with Obstructive Sleep Apnea. Respiration. 2009; 77.
- El Solh AA. Nursing home acquired pneumonia.. Seminars in Respiratory and Critical Care Medicine.. 2009; 30.
- El Solh AA. Ceftobiprole: anew broad spectrum cephalosporin.. Expert Opinion on Pharmacotherapy. 2009; 10.
- El Solh AA, Alhajhusain A.. Update on the treatment of Pseudomonas aeruginosa.. Journal of Antimicrobial Chemotherapy. 2009; 64(2).
- Lisboa T., Re;;p J., Richart C., Anzueto A., El Solh AA. Obesity and critical care.. Clinical Pulmonary Medicine. 2009; 16.
- El Solh AA. Airway management of patients with obesity.. Clinics in Chest Medicine. 2009; 30(3).
- El Solh AA, Akinnusi ME, Berim IG, Peter AM, Paasch LL, Szarpa KR, El Solh AA. Hemostatic implications of endothelial cell apoptosis in obstructive sleep apnea. Sleep Breath. 2008; 12(4).
- Akinnusi ME, Paasch LL, Szarpa KR, Wallace PK, El Solh AA, El Solh AA. Impact of nasal continuous positive airway pressure therapy on markers of platelet activation in patients with obstructive sleep apnea. Respiration. 2008; 77(1).
- El Solh AA, Akinnusi ME, Wiener-Kronish JP, Lynch SV, Pineda LA, Szarpa K, El Solh AA. Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia. Am J Respir Crit Care Med. 2008; 178(5).
- El Solh AA, Akinnusi ME, Peter M, Berim I, Schultz MJ, Pineda L, El Solh AA. Triggering receptors expressed on myeloid cells in pulmonary aspiration syndromes. Intensive Care Med. 2008; 34(6).
- El Solh AA, Akinnusi ME, Alsawalha LN, Pineda LA,. Outcome of septic shock in older adults after implementation of the sepsis "bundle". J Am Geriatr Soc. 2008; 56(2).
- Akinnusi ME, Pineda LA, El Solh AA. Impact of obesity on intensive care morbidity and mortality: a meta-analysis. Crit Care Med. 2008; 36(1).
- Akinnusi ME, Pineda LA, El Solh AA, El Solh AA. Effect of obesity on intensive care morbidity and mortality: a meta-analysis. Crit Care Med. 2008; 36(1).
- El Solh AA, Florescu I., Dimov R., Razbadauskas A., Bochan M., Fichev G., Dukart G., Babinchak T., Cooper C. A., Ellis-Grosse E. J., Dartois N., Gandjini H. 307 Study Group. Efficacy and safety of tigecycline compared with vancomycin or linezolid for treatment of serious infections with methicillin-resistant Staphylococcus aureus or vancomycin-resistant enterococci: a Phase 3, multicentre, double-blind, rand. J Antimicrob Chemother. 2008; 62(1).
- El Solh AA, Saliba R, El Solh AA. Pharmacologic prevention of aspiration pneumonia: a systematic review. Am J Geriatr Pharmacother. 2007; 5(4).
- Akinnusi ME, El Solh AA, El Solh AA. The role of coagulation in pulmonary pathology. Inflamm Allergy Drug Targets. 2007; 6(4).
- El Solh AA, Aldik Z, Alnabhan M, Grant B,. Predicting effective continuous positive airway pressure in sleep apnea using an artificial neural network. Sleep Med. 2007; 8(5).
- El Solh AA, Akinnusi ME, Baddoura FH, Mankowski CR. Endothelial cell apoptosis in obstructive sleep apnea: a link to endothelial dysfunction. Am J Respir Crit Care Med. 2007; 175(11).
- El Solh AA, Choi G, Schultz MJ, Pineda LA, Mankowski C.. Clinical and hemostatic responses to treatment in ventilator-associated pneumonia: role of bacterial pathogens. Crit Care Med. 2007; 35(2).
- El Solh AA, Akinnusi ME, Pineda LA, Mankowski CR. Diagnostic yield of quantitative endotracheal aspirates in patients with severe nursing home-acquired pneumonia. Crit Care. 2007; 11(3).
- El Solh AA, Ramadan FH. Overview of respiratory failure in older adults. J Intensive Care Med. 2006; 21(6).
- Bosinski TJ, El Solh AA. Recombinant factor VIIa, its clinical properties, and the tissue factor pathway of coagulation. Mini Rev Med Chem. 2006; 6(10).
- Schünemann HJ, Jaeschke R, Cook DJ, Bria WF, El Solh AA, Ernst A, Fahy BF, Gould MK, Horan KL, Krishnan JA, Manthous CA, Maurer JR, McNicholas WT, Oxman AD, Rubenfeld G, Turino GM, Guyatt G. An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations. Am J Respir Crit Care Med. 2006; 174(5).
- El Solh AA, Aquilina AT, Pineda LA, Dhanvantri V, Grant BJ, Bouquin P. Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patients. Eur Respir J. 2006; 28(3).
- El Solh AA, Pineda LA, Bouquin P, Mankowski C. Determinants of short and long term functional recovery after hospitalization for community-acquired pneumonia in the elderly: role of inflammatory markers. BMC Geriatr. 2006; 6.
- El Solh AA, Saliba R, Bosinski T, Grant BJ, Berbary E, Miller N. Allopurinol improves endothelial function in sleep apnoea: a randomised controlled study. Eur Respir J. 2006; 27(5).
- El Solh AA, Bhora M, Pineda L, Dhillon R. Nosocomial pneumonia in elderly patients following cardiac surgery. Respir Med. 2006; 100(4).
- El Solh AA, Pineda LA, Bouquin, P., Mankowski, C.. Association between inflammatory markers and functional decline after community acquired pneumonia in the elderly: a prospective cohort study.. BMC Geriatrics. 2006; 6(12).
- El Solh AA, Aquilina AT, Pineda LA, Dhavantri V., Grant BJ, Bouquin, P.. Noninvasive ventilation for prevention of post extubation respiratory failure in obese patients.. European Respiratory. 2006; 28.
- El Solh AA, Schunemann H., Jaesckle R., Cook D., Bria W., Fahy B., Ernst A., Gould M., Horan K., Krishnan J., Manthous C., Maurer J., McNicholas W., Rubenfeld G., Turino G, Guyatt G. on behalf of the ATS Documents and Devel. Grading the quality of evidence and strength of recommendations in guidelines - An Official ATS Statement. American Journal of Respiratory and Critical Care Medicine. 2006; 174.
- El Solh AA, Abdo T., Pineda LA, Ramadan F, Berbary E.. A longitudinal study of idiopathic exudative lymphocytic pleural effusion in the elderly. Journal of the American Geriatrics Society. 2005; 53.
- El Solh AA, Abdo T, Pineda LA, Ramadan F, Berbary E. A longitudinal study of idiopathic exudative lymphocytic pleural effusion in older people. J Am Geriatr Soc. 2005; 53(11).
- Ramadan FH, Masoodi N, El Solh AA. Clinical factors associated with hyperkalemia in patients with congestive heart failure. J Clin Pharm Ther. 2005; 30(3).
- El Solh AA, Brewer T, Okada M, Bashir O, Gough M,. Indicators of recurrent hospitalization for pneumonia in the elderly. J Am Geriatr Soc. 2004; 52(12).
- El-Solh AA, Okada M, Pietrantoni C, Aquilina A, Berbary E, El Solh AA. Procoagulant and fibrinolytic activity in ventilator-associated pneumonia: impact of inadequate antimicrobial therapy. Intensive Care Med. 2004; 30(10).
- El Solh AA, Pietrantoni C, Bhat A, Bhora M, Berbary E,. Indicators of potentially drug-resistant bacteria in severe nursing home-acquired pneumonia. Clin Infect Dis. 2004; 39(4).
- El Solh AA, Bhat A, Gunen H, Berbary E. Extubation failure in the elderly. Respir Med. 2004; 98(7).
- El Solh AA. Clinical approach to the critically ill, morbidly obese patient. Am J Respir Crit Care Med. 2004; 169(5).
- Aquilina AT, Gunen H, Ramadan F, El Solh AA. Radiographic resolution of community-acquired bacterial pneumonia in the elderly. J Am Geriatr Soc. 2004; 52(2).
- Nara, W, El Solh AA. Sleep disorders in morbidly obese. Sleep Review. 2004; 5.
- El Solh AA, Pietantoni, C, Bhat, A, Okada, M, Zambon M, Aquilina AT, Berbary, E. Colonization of dental plaques: A reservoir of pathogens for hospital-acquired pneumonia in institutionalized elders. Chest. 2004; 126.
- El Solh AA, Okada M, Pietrantoni C, Aquilina AT, Berbary E. Procoagulant and fibrinolytic activity in ventilator associated pneumonia: impact of inadequate antimicrobial therapy.. Intensive Care Medicine. 2004; 30.
- Magalang UJ, Dmochowski J, Veeramachaneni S, Draw A, Mador MJ, El Solh AA, Grant BJ. Prediction of the apnea-hypopnea index from overnight pulse oximetry. Chest. 2003; 124(5).
- El Solh AA, Magalang UJ, Mador MJ, Dmochowski J, Veeramachaneni S, Saberi A, Draw AM, Lieber BB, Grant BJ. The utility of neural network in the diagnosis of Cheyne-Stokes respiration. J Med Eng Technol. 2003; 27(2).
- El Solh AA, Peitrantoni, C, Bhat, A, Aquilina, T, Okada, M, Grover, V, Gifford, N. Microbiology of severe aspiration in the elderly. American Journal of Respiratory & Critical Care Medicine. 2003; 167.
- El Solh AA, Okada, M, Bhat, A, Pietrantoni, C. Swallowing disorders post orotracheal intubation in the elderly. Intensive Care Medicine. 2003; 29.
- Pietrantoni C., El Solh AA. Respiratory complications of obesity: Weighty issues. Advance for Managers of Respiratory Care. 2003; 12.
- El Solh AA, Bozkanat E, Mador MJ, Grant BJ. Association between plasma endothelin-1 levels and Cheyne-Stokes respiration in patients with congestive heart failure. Chest. 2002; 121(6).
- El Solh AA, Mador MJ, Sikka P., Roth M., Dhillon RS, Grant BJ. Adhesion molecules in coronary artery disease patients with sleep apnea.. Chest. 2002; 121.
- El Solh AA, Aquilina AT, Dhillon, R., Ramadan F, Nowak, P., Davies, J.. Antimicrobial treatment failure in institutionalized elderly with severe pneumonia.. . American Journal of Respiratory and Critical Care Medicine. 2002; 166.
- El Solh AA, Bozkanat, E, Roth, M, Mador M, Grant BJ. Association between plasma endothelian-1 levels and Cheyne-Stokes respiration in patients with congestive heart failure. Chest. 2002; 121.
- Sikka P, Bozkanat E, Jaafar W, Davies J, El Solh AA. Morbid obesity in the medical ICU. Chest. 2001; 120(6).
- Sikka P, Ramadan F, Davies J, El Solh AA. Etiology of severe pneumonia in the very elderly. Am J Respir Crit Care Med. 2001; 163(3 Pt).
- El Solh AA, Sikka, P, Ramadan F, Davies, J. Etiology of severe pneumonia in the very elderly. American Journal of Respiratory & Critical Care Medicine. 2001; 163.
- El Solh AA, Sikka, P, Jaafar, W, Bozkanat, E. Outcome of critically obese patients admitted to the medical intensive care unit. Chest. 2001; 120.
- El Solh AA, Sikka, P, Ramadan F. Outcome of severe pneumonia in the elderly predicted by recursive partitioning. Journal of the American Geriatrics Society. 2001; 49.
- Sikka, P, Jaafar, W, Bozkanat, E, El Solh AA. A comparison of severity of illness scoring systems for elderly patients with severe pneumonia. Intensive Care Medicine. 2000; 26.
- El-Solh AA, Hsiao CB, Goodnough S, Serghani J, Grant BJ, El Solh AA. Predicting active pulmonary tuberculosis using an artificial neural network. Chest. 1999; 116(4).
- el-Solh AA, Mador MJ, Ten-Brock E, Shucard DW, Abul-Khoudoud M, Grant BJ, El Solh AA. Validity of neural network in sleep apnea. Sleep. 1999; 22(1).
- El Solh AA, Mador MJ, Tenbrock E, Shucard DW, Abul-Khoudoud, M, Grant BJ. Validity of an artificial neural network in predicting sleep apnea. Sleep. 1999; 22.
- El Solh AA, Hsiao CB, Goodnough, S, Serghani, J, Grant BJ. Predicting active pulmonary tuberculosis using an artificial neural network. Chest. 1999; 116.
- El Solh AA, Nopper, J, Sherif, A, Aquilina AT, Grant BJ. Comparison of clinical and radiographic manifestations of uncommon nontuberculous myocobacterial disease in AIDS patients. Chest. 1998; 114.
- El Solh A, Joseph Mylotte, Sherif S, Serghani J, Brydon Grant. Validity of a decision tree for predicting active pulmonary tuberculosis from clinical and radiographic data.. Am J Respir Crit Care Med. 1997; 155(5).
- El-Solh A, Mylotte J, Sherif S, Serghani J, Grant BJ, El Solh AA. Validity of a decision tree for predicting active pulmonary tuberculosis. Am J Respir Crit Care Med. 1997; 155(5).
- El Solh AA, Grant BJ. A comparison of severity of illness scoring systems for critically ill obstetric patients.. Chest. 1996; 110(5).
- El-Solh AA, Stubeusz DL, Grant GB, Grant JB, El Solh AA. Outcome of AIDS patients requiring mechanical ventilation predicted by recursive partitioning. Chest. 1996; 109(6).
- El Solh AA. Outcome of patients with AIDS requiring mechanical ventilation predicted by recursive partitioning Chest. 1996; 109.
Books and Book Chapters:
- El Solh AA. What are the special considerations in the management of the morbidly obese patients in the ICU? Book Chapter in The Evidenced Based Practice of Critical Care. In Press.. 2010.
- El Solh AA. Health Care Associated Pneumonia. Book chapter in Respiratory Infections. 2010.
- El Solh AA. Anaerobic infections. Book chapter in Encyclopedia of Intensive Care Medicine. (In press). Encyclopedia of Intensive Care Medicine. 2010.
- El Solh AA. Aspiration syndromes (chapter of Respiratory Emergencies). 2006.
- Shucard D., Parmenter B., El Solh AA. Computer Analysis of Sleep. Chapter in Encyclopedia of Medical Devices and Instrumentation, 2nd Edition. 2006.
Abstracts:
- El Solh AA, Sikka P., Davies J., Aquilina AT, Naughton BJ, Ramadan F, Grant BJ. Etiology of severe pneumonia requiring mechanical ventilation in the elderly. (abstract). Am J Respir Crit Care Med. 2000; 161(A294).
- El Solh AA, Mylotte JM, Sherif S., Serghani J., Aquilina AT, Hsiao CB, Grant BJ. Prediction of active pulmonary tuberculosis using artificial neural network. (abstract). Am J Respir Crit Care Med. 1999; 159(A16).
- El Solh AA, Hsiao CB, Goodnough S., Grant BJ. Outcome of patients with Streptococcus pneumoniae bacteremia predicted by recursive partitioning. (abstract). Chest. 1999; 116(369S).
- El Solh AA, Mador MJ, Ten Brock E, Shucard D, Grant BJ. Validity of an artificial neural network in predicting sleep apnea. (abstract). Am J Respir Crit Care Med. 1998; 157(A852).
- Ten Brock E, El Solh AA, Miller M., Schnapp M., Graham S., Houck J., Grant BJ. The effect of partial ventriculectomy on exercise capacity and quality of life in patients with dilated cardiomyopathy. (abstract). Chest. 1998; 114(312S).
- El Solh AA, Mylotte JM, Sherif S., Serghani J., Grant BJ. Validity of decision tree for predicting active pulmonary tuberculosis from clinical and radiographic data. (abstract). Am J Respir Crit Care Med. 1997; 155(A27).
- El Solh AA, Nopper J., Sherif S., Aquilina AT, Grant BJ. Comparison of clinical and radiographic manifestations of uncommon nontuberculous mycobacterial disease in AIDS patients. (abstract). Am J Respir Crit Care Med. 1997; 155(A134).
- Grant BJ, El Solh AA, Stein P.D.. Artificial neural network for diagnosis of acute pulmonary embolism. (abstract). Am J Respir Crit Care Med. 1997; 155(A112).
- El Solh AA, Grant BJ. A comparison of severity of illness scoring systems for critically ill obstetric patients. (abstract). Am J Respir Crit Care Med. 1996; 153(A362).
- El Solh AA, Kumar N.M., Lwebuga-Mukasa JS. HIV-1 derived peptides modulate expression of protooncogenes in human bronchoalveolar carcinoma cell line, A549. (abstract). Am J Respir Crit Care Med. 1995; 151(A161).
- El Solh AA, Stubeusz D.L., Grant BJ. Outcome of patients with AIDS requiring mechanical ventilation predicted by recursive partitioning. (abstract). Am J Respir Crit Care Med. 1995; 151(A488).
- Kumar M.N., El Solh AA, Nair M.P.N., Schwartz SA, Lwebuga-Mukasa JS. Induction of protooncogenes and apoptosis in uninfected lung alveolar epithelial cells by HIV-1 derived peptides. (abstract). Great Lakes Lung Conference, Ontario, Canada.. 1995.
- Kumar, N.M., El Solh AA, Schwartz SA, Lwebuga-Mukasa JS. HIV-1 TAT and GP120-derived peptides modulate rat lung alveolar epithelial cell protooncogenes, and cytokine gene expression. (Abstract). Great Lakes Lung Conference, Ontario, Canada. 1994.
Evaluative Studies and Case Reports:
- El Solh AA, Niederman MS, Drinka P. Nursing home-acquired pneumonia: a review of risk factors and therapeutic approaches. Curr Med Res Opin. 2010; 26(12).
- El Solh AA, Bhora M, Pineda LA, Aquilina AT, Abbetessa L, Berbary E. Alveolar plasminogen activator inhibitor-1 predicts ARDS in aspiration pneumonitis. Intensive Care Med. 2006; 32(1).
- El-Solh A, Sikka P, Draw A, El Solh AA. A 58-year old woman with recurrent productive cough and diarrhea. Chest. 2000; 118(4).
- El Solh AA, Sikka, P, Draw, A. Pulmonary and Critical Pearls: A 58 y/o woman with recurrent productive cough and diarrhea. Chest. 2000; 118.
- El Solh AA. Poorly differentiated carcinoma of the mediastinum: A case of germ cell tumor. Resident & Staff Physician. 1997; 43(9).
- el-Solh A, Ameen K, Sherif S, El Solh AA. Endobronchial non-Hodgkin's lymphoma in an AIDS patient. Respir Med. 1995; 89(10).
- El Solh AA, Ameen, K, Sherif, S. Endobronchial non-hodgkin‘s lymphoma in an AIDS patient. Respiratory Medicine. 1995; 89.
Professional Memberships:
- Fellow, American College of Physicians (1998–present)
- Fellow, American College of Chest Physicians (1998–present)
- American College of Physicians/Am. Soc. of Internal Medicine; Medicine (1993–1998)
Service Activities:
- Editorial Board Member for Current Respiratory Medicine Reviews; Editorial Board Member (2004–present)
- Journal Reviewer; Cochrane Anesthesia Review Group; Reviewer (2004–present)
- Journal Reviewer; Critical Care Medicine; Reviewer (2004–present)
- Journal Reviewer; Chest; Reviewer (2004–present)
- Journal Reviewer; Expert Review of Anti-infective Therapy; Reviewer (2004–present)
- Member, Laboratory Medicine Utilization Review, ECMC; Member (2003–2004)
- Editorial Board Member for the Am. Jrn. of Respiratory & Critical Care Medicine; Editorial Board Member (2003–present)
- Journal Reviewer; Clinical Infectious Diseases; Reviewer (2003–present)
- Journal Reviewer; Journal of American Geriatrics Society; Reviewer (2003–present)
- National Study Section; Research Council, American Lung Association of New York; Member (2003–present)
- Member, Pharmacy&Therapeutics Committee, ECMC; Member (2001–2003)
- Journal Reviewer; American Journal of Respiratory & Critical Care Medicine; Reviewer (2001–present)
- Member, Clinical Pathway Committee, ECMC; Member (2000–2003)
- Member, Medical Executive Committee, BGH; Member (1997–1998)
- Member, Mortality & Morbidity Committee, ECMC; Member (1992–1993)
- Member, Quality Assurance Committee, ECMC; Member (1992–1993)
- Member, Pharmacy & Therapeutics Committee, ECMC; Member (1992–1993)