UB team proposes genome 'archipelago' as new model of how genomic information influences development & disease

Niagara Frontier Publications and Technology.org published the announcement about a UB team has developed a new model of how information in the genome is organized, called the novel genome archipelago model (GAM). The model provides new insights into how a multitude of interactions among genes may affect normal development as well as mutations that lead to cancer and other diseases. “GAM offers a physical basis for the idea of systems genomics, which has begun to emerge in recent years, in which individual genome elements are integrated into an ‘organism-like’ entity,” said Michal K. Stachowiak, professor in the department of pathology and anatomical sciences in the Jacobs School of Medicine and Biomedical Sciences.