This facility offers high-throughput, next-generation sequencing on two illumina HiSeq2500 and MiSeq platforms. We have expertise in whole-genome, exome, epigenetic and microbiome sequencing, and we work in conjunction with a team of bioinformaticists to help facilitate rapid analysis and algorithm deployment, as well as data storage and management.
In addition to our deep sequencing offerings, we also provide gene expression analysis services on Affymetrix platforms, including 3’-expression, miRNA, exon and gene arrays.
Our illumina HiSeq 2500 platform supports a variety of different experiments, including whole-genome and candidate-region sequencing, transcriptome analysis, small RNA discovery, methylation profiling and protein-nucleic acid interaction analysis at a genome-wide scale. It is an excellent platform for projects that need broad coverage and can accommodate short read lengths.
Standard analysis of sequencing data generated at our facility includes FastQC quality reports and assay specific genomic alignments.
Our analysis offerings currently include:
Our Affymetrix Gene Chip System provides expression analysis services on all Affymetrix Gene Chips, including 3’-expression, miRNA, exon and gene arrays.
It performs sample quality analysis using the Agilent 2100 Bioanalyzer, target labeling, fragmentation, hybridization, staining and scanning.
Lab personnel conduct initial data analysis. You can arrange additional data analysis services with bioinformatics specialists at the University at Buffalo or Roswell Park Comprehensive Cancer Center.
UB New York State Center of Excellence in Bioinformatics and Life Sciences
Buffalo Niagara Medical Campus
701 Ellicott Street
Buffalo, NY 14203
Sujith A. Valiyaparambil
Center of Excellence in Bioinformatics and Life Sciences Lab #B3-123
701 Ellicott Street, Buffalo, NY 14203
Phone: (716) 881-7514
701 Ellicott Street Room B2-293 Center of Excellence BUFFALO, NY 14203